ritonavir and Conjunctivitis--Allergic

ritonavir has been researched along with Conjunctivitis--Allergic* in 1 studies

Other Studies

1 other study(ies) available for ritonavir and Conjunctivitis--Allergic

ArticleYear
Ritonavir and Topical Ocular Corticosteroid Induced Cushing's Syndrome in an Adolescent With HIV-1 Infection.
    The Pediatric infectious disease journal, 2017, Volume: 36, Issue:5

    Cushing's syndrome after topical ocular corticosteroid use is extremely rare. We describe a case of symptomatic Cushing's syndrome in an adolescent male with sight-threatening vernal keratoconjunctivitis on antiretroviral therapy for HIV-1 infection that included ritonavir, a potent cytochrome p450 CYP3A4 inhibitor. CYP3A4 inhibition reduces the metabolism of exogenous corticosteroids leading to suppression of endogenous steroid production and Cushing's syndrome.

    Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Conjunctivitis, Allergic; Cushing Syndrome; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; HIV Infections; HIV Protease Inhibitors; Humans; Male; Ritonavir

2017