ritanserin has been researched along with Tuberous Sclerosis in 1 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
Tuberous Sclerosis: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kovalenko, A | 1 |
| Sanin, A | 1 |
| Kosmas, K | 1 |
| Zhang, L | 1 |
| Wang, J | 1 |
| Akl, EW | 1 |
| Giannikou, K | 1 |
| Probst, CK | 1 |
| Hougard, TR | 1 |
| Rue, RW | 1 |
| Krymskaya, VP | 1 |
| Asara, JM | 1 |
| Lam, HC | 1 |
| Kwiatkowski, DJ | 1 |
| Henske, EP | 1 |
| Filippakis, H | 1 |
1 other study available for ritanserin and Tuberous Sclerosis
| Article | Year |
|---|---|
Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex.
Topics: Angiolipoma; Animals; Autophagy; Cell Proliferation; Chloroquine; Diacylglycerol Kinase; Down-Regula | 2021 |