ritanserin has been researched along with Sleep Initiation and Maintenance Disorders in 3 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ritanserin treatment was associated with a dose-related prolongation of subjects' QTc interval recording on the electrocardiogram." | 2.68 | Ritanserin in the treatment of alcohol dependence--a multi-center clinical trial. Ritanserin Study Group. ( Anton, RF; Bohn, MJ; Clyde, C; Galloway, GP; Jasinski, DR; Johnson, BA; Kranzler, H; Mason, BJ; Pettinati, HM; Rawson, R; Weinreib, R, 1996) |
| "Ritanserin was given at a daily dose of 10 mg for 28 days and was preceded (10 days) and followed (2 days) by a placebo." | 2.67 | The effects of ritanserin on mood and sleep in abstinent alcoholic patients. ( Alterwain, P; Alvariño, F; Estévez, F; Giusti, M; Labraga, P; Monti, JM; Olivera, S, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Monti, JM | 1 |
| Alterwain, P | 1 |
| Estévez, F | 1 |
| Alvariño, F | 1 |
| Giusti, M | 1 |
| Olivera, S | 1 |
| Labraga, P | 1 |
| Johnson, BA | 1 |
| Jasinski, DR | 1 |
| Galloway, GP | 1 |
| Kranzler, H | 1 |
| Weinreib, R | 1 |
| Anton, RF | 1 |
| Mason, BJ | 1 |
| Bohn, MJ | 1 |
| Pettinati, HM | 1 |
| Rawson, R | 1 |
| Clyde, C | 1 |
| Dahlitz, M | 1 |
| Wells, P | 1 |
| James, R | 1 |
| Idzikowski, C | 1 |
| Parkes, JD | 1 |
2 trials available for ritanserin and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
The effects of ritanserin on mood and sleep in abstinent alcoholic patients.
Topics: Adult; Affect; Alcoholism; Anxiety; Humans; Male; Middle Aged; Ritanserin; Sleep; Sleep Initiation a | 1993 |
Ritanserin in the treatment of alcohol dependence--a multi-center clinical trial. Ritanserin Study Group.
Topics: Adult; Alcoholism; Double-Blind Method; Female; Headache; Humans; Male; Middle Aged; Rhinitis; Ritan | 1996 |
1 other study available for ritanserin and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Treatment of insomnia with ritanserin.
Topics: Adult; Female; Humans; Piperidines; Ritanserin; Serotonin Antagonists; Sleep Initiation and Maintena | 1990 |