ritanserin has been researched along with Pyrexia in 9 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As part of our characterization of the developmental consequences of prenatal cocaine exposure, cocaine was injected into eggs containing viable chicken embryos on embryonic day (E) 18 and the fever response to the endotoxin lipopolysaccharide (LPS) and a delayed-type hypersensitivity response to phytohemagglutinin (PHA) were assessed postnatally." | 3.71 | Embryonic "binge" cocaine exposure alters neural-immune and neural-endocrine interactions in young chickens: involvement of serotonin(2) receptors. ( Schrott, LM; Sparber, SB, 2001) |
| " LPS administration induces a syndrome collectively known as sickness behavior, manifest as altered thermoregulatory processes leading to fever, and increased serum concentrations of neuroendocrine hormones, including corticosterone." | 3.70 | Late embryonic ritanserin exposure fails to alter normal responses to immune system stimulation in young chicks. ( Bodensteiner, KE; Schrott, LM; Sparber, SB; Sweeney, WA, 1999) |
| "Pretreatment with propranolol (10 mg/kg), a 5-HT(1A) receptor antagonist as well as a beta-blocker, and dantrolene (20 mg/kg), a peripheral muscle relaxant, did not prevent the death of the animals, even though these two drugs suppressed the increase in rectal temperature to some extent." | 1.31 | Potent serotonin (5-HT)(2A) receptor antagonists completely prevent the development of hyperthermia in an animal model of the 5-HT syndrome. ( Katoh, S; Nisijima, K; Yoshino, T; Yui, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wierońska, JM | 2 |
| Stachowicz, K | 2 |
| Pałucha-Poniewiera, A | 2 |
| Acher, F | 1 |
| Brański, P | 2 |
| Pilc, A | 2 |
| Schrott, LM | 2 |
| Sweeney, WA | 1 |
| Bodensteiner, KE | 1 |
| Sparber, SB | 2 |
| Raghavendra, V | 1 |
| Kulkarni, SK | 1 |
| Nisijima, K | 1 |
| Yoshino, T | 1 |
| Yui, K | 1 |
| Katoh, S | 1 |
| Yamada, J | 1 |
| Sugimoto, Y | 1 |
| Ohkura, M | 1 |
| Inoue, K | 1 |
| Mechan, AO | 1 |
| Esteban, B | 1 |
| O'Shea, E | 1 |
| Elliott, JM | 1 |
| Colado, MI | 1 |
| Green, AR | 1 |
| Lecci, A | 1 |
| Borsini, F | 1 |
| Mancinelli, A | 1 |
| D'Aranno, V | 1 |
| Stasi, MA | 1 |
| Volterra, G | 1 |
| Meli, A | 1 |
9 other studies available for ritanserin and Pyrexia
| Article | Year |
|---|---|
Metabotropic glutamate receptor 4 novel agonist LSP1-2111 with anxiolytic, but not antidepressant-like activity, mediated by serotonergic and GABAergic systems.
Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Antidepressive Agents; Diazepam; Fever; Flumazenil; GA | 2010 |
On the mechanism of anti-hyperthermic effects of LY379268 and LY487379, group II mGlu receptors activators, in the stress-induced hyperthermia in singly housed mice.
Topics: Amino Acids; Analysis of Variance; Animals; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, | 2012 |
Late embryonic ritanserin exposure fails to alter normal responses to immune system stimulation in young chicks.
Topics: Adjuvants, Immunologic; Animals; Antipsychotic Agents; Chick Embryo; Chickens; Corticosterone; Fever | 1999 |
Melatonin reversal of DOI-induced hypophagia in rats; possible mechanism by suppressing 5-HT(2A) receptor-mediated activation of HPA axis.
Topics: Adrenal Glands; Amphetamines; Animals; Anorexia; Ascorbic Acid; Exploratory Behavior; Feeding Behavi | 2000 |
Potent serotonin (5-HT)(2A) receptor antagonists completely prevent the development of hyperthermia in an animal model of the 5-HT syndrome.
Topics: 5-Hydroxytryptophan; Animals; Anterior Hypothalamic Nucleus; Antidepressive Agents; Body Temperature | 2001 |
Embryonic "binge" cocaine exposure alters neural-immune and neural-endocrine interactions in young chickens: involvement of serotonin(2) receptors.
Topics: Animals; Basophils; Chick Embryo; Chickens; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Fev | 2001 |
Effects of the 5-HT2 receptor antagonist, ritanserin on hyperthermia and depletion of 5-HT in frontal cortex induced by a 5-HT releasing drug, p-chloroamphetamine (PCA) in mice.
Topics: Animals; Body Temperature; Fever; Male; Mice; p-Chloroamphetamine; Prefrontal Cortex; Receptors, Ser | 2001 |
The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to rats.
Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Animals; Benzazepines; Body Temperature; Corpus Striat | 2002 |
Effect of serotoninergic drugs on stress-induced hyperthermia (SIH) in mice.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Body | 1990 |