ritanserin has been researched along with Obsessive-Compulsive Disorder in 5 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The selective serotonin reuptake inhibitor (SSRI) fluvoxamine has been used in an attempt to understand whether there is a biological distinction among anxiety disorders." | 7.69 | Biological dissection of anxiety disorders: the clinical role of selective serotonin reuptake inhibitors with particular reference to fluvoxamine. ( De Leeuw, AS; den Boer, JA; van Vliet, IM; Westenberg, HG, 1995) |
| "The selective serotonin reuptake inhibitor (SSRI) fluvoxamine has been used in an attempt to understand whether there is a biological distinction among anxiety disorders." | 3.69 | Biological dissection of anxiety disorders: the clinical role of selective serotonin reuptake inhibitors with particular reference to fluvoxamine. ( De Leeuw, AS; den Boer, JA; van Vliet, IM; Westenberg, HG, 1995) |
| " Each subject was tested two times, receiving both times the same dosage of mCPP or placebo with ritanserin or placebo pre-treatment." | 2.73 | Hypersensitivity of 5-HT2 receptors in OCD patients. An increased prolactin response after a challenge with meta-chlorophenylpiperazine and pre-treatment with ritanserin and placebo. ( de Leeuw, AS; Westenberg, HG, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tucci, MC | 1 |
| Dvorkin-Gheva, A | 1 |
| Johnson, E | 1 |
| Wong, M | 1 |
| Szechtman, H | 1 |
| de Leeuw, AS | 2 |
| Westenberg, HG | 2 |
| Kaurav, BP | 1 |
| Wanjari, MM | 1 |
| Chandekar, A | 1 |
| Chauhan, NS | 1 |
| Upmanyu, N | 1 |
| den Boer, JA | 1 |
| van Vliet, IM | 1 |
| Bach, M | 1 |
| Aigner, M | 1 |
| Lenz, G | 1 |
1 trial available for ritanserin and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Hypersensitivity of 5-HT2 receptors in OCD patients. An increased prolactin response after a challenge with meta-chlorophenylpiperazine and pre-treatment with ritanserin and placebo.
Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Male; Middle Aged; Obsessiv | 2008 |
4 other studies available for ritanserin and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
5-HT2A/C receptors do not mediate the attenuation of compulsive checking by mCPP in the quinpirole sensitization rat model of obsessive-compulsive disorder (OCD).
Topics: Animals; Compulsive Behavior; Disease Models, Animal; Male; Obsessive-Compulsive Disorder; Piperazin | 2015 |
Influence of Withania somnifera on obsessive compulsive disorder in mice.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Female; Male; Mice; Motor Activity; Obsessive-Co | 2012 |
Biological dissection of anxiety disorders: the clinical role of selective serotonin reuptake inhibitors with particular reference to fluvoxamine.
Topics: Anxiety Disorders; Fluvoxamine; Humans; Maprotiline; Obsessive-Compulsive Disorder; Panic; Receptors | 1995 |
Ritanserin as adjunct to fluoxetine treatment of OCD patients with psychotic features.
Topics: Adult; Antidepressive Agents, Second-Generation; Drug Therapy, Combination; Female; Fluoxetine; Huma | 1997 |