ritanserin has been researched along with Nelson Syndrome in 1 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
Nelson Syndrome: A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketanserin was given to 2 patients with Nelson's syndrome, with only transient ACTH decrease in one, and no changes in ACTH response to CRH after 1 month treatment in both cases." | 2.69 | Effect of the serotonin antagonists ritanserin and ketanserin in Cushing's disease. ( Belluardo, P; Boscaro, M; Fallo, F; Fava, GA; Franceschetto, A; Sonino, N, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sonino, N | 1 |
| Fava, GA | 1 |
| Fallo, F | 1 |
| Franceschetto, A | 1 |
| Belluardo, P | 1 |
| Boscaro, M | 1 |
1 trial available for ritanserin and Nelson Syndrome
| Article | Year |
|---|---|
Effect of the serotonin antagonists ritanserin and ketanserin in Cushing's disease.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Female; Hormones; Humans; Hydrocor | 2000 |