Page last updated: 2024-11-03

ritanserin and Muscle Contraction

ritanserin has been researched along with Muscle Contraction in 9 studies

Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's6 (66.67)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wainscott, DB1
Cohen, ML2
Schenck, KW2
Audia, JE1
Nissen, JS1
Baez, M1
Kursar, JD1
Lucaites, VL1
Nelson, DL1
Bonhaus, DW1
Flippin, LA1
Greenhouse, RJ1
Jaime, S1
Rocha, C1
Dawson, M1
Van Natta, K1
Chang, LK1
Pulido-Rios, T1
Webber, A1
Leung, E1
Eglen, RM1
Martin, GR1
Hernández, M1
Barahona, MV1
Simonsen, U1
Recio, P1
Rivera, L1
Martínez, AC1
García-Sacristán, A1
Orensanz, LM1
Prieto, D1
Veasey, SC1
Panckeri, KA1
Hoffman, EA1
Pack, AI1
Hendricks, JC1
Okoro, EO1
Marwood, JF1
Wappler, F2
Scholz, J2
Oppermann, S1
von Richthofen, V1
Steinfath, M2
Schulte am Esch, J2
Fiege, M1
Richter, A1
Weisshorn, R1
Tuladhar, BR1
Womack, MD1
Naylor, RJ1
Kurz, KD1

Trials

1 trial available for ritanserin and Muscle Contraction

ArticleYear
Ritanserin attenuates the in vitro effects of the 5-HT2 receptor agonist DOI on skeletal muscles from malignant hyperthermia-susceptible patients.
    Journal of clinical anesthesia, 1997, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Amphetamines; Female; Humans; In Vitro Techniques; Male; Malignant Hyperthermia;

1997

Other Studies

8 other studies available for ritanserin and Muscle Contraction

ArticleYear
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate;

1993
RS-127445: a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist.
    British journal of pharmacology, 1999, Volume: 127, Issue:5

    Topics: Animals; Calcium; CHO Cells; Cricetinae; Humans; Male; Muscle Contraction; Pyrimidines; Radioligand

1999
Characterization of the 5-hydroxytryptamine receptors mediating contraction in the pig isolated intravesical ureter.
    British journal of pharmacology, 2003, Volume: 138, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Female; Guanethidine; In Vitro Techniques; Male; Muscle C

2003
The effects of serotonin antagonists in an animal model of sleep-disordered breathing.
    American journal of respiratory and critical care medicine, 1996, Volume: 153, Issue:2

    Topics: Animals; Diaphragm; Dogs; Electromyography; Laryngeal Muscles; Methysergide; Muscle Contraction; Mus

1996
Effects of 5HT2 receptor antagonists on responses to potassium depolarization in rat isolated aorta.
    Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:1

    Topics: Animals; Aorta, Thoracic; Cinnarizine; Cyproheptadine; Diltiazem; Drug Synergism; Felodipine; Female

1997
5-HT2 receptor antagonist-mediated inhibition of halothane-induced contractures in skeletal muscle specimens from malignant hyperthermia susceptible patients.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:4

    Topics: Adolescent; Adult; Anesthetics, Inhalation; Caffeine; Child; Dose-Response Relationship, Drug; Drug

1999
Pharmacological characterization of the 5-HT receptor-mediated contraction in the mouse isolated ileum.
    British journal of pharmacology, 2000, Volume: 131, Issue:8

    Topics: Animals; Atropine; Dioxanes; Dose-Response Relationship, Drug; Female; Granisetron; Ileum; In Vitro

2000
5-HT2-receptor antagonists: alpha 1- vs. 5-HT2-receptor blocking properties in blood vessels.
    Journal of cardiovascular pharmacology, 1988, Volume: 11 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Ergolines; Ketanserin; Male; Muscle Contracti

1988