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ritanserin and Mental Disorders

ritanserin has been researched along with Mental Disorders in 5 studies

Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.

Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.

Research Excerpts

ExcerptRelevanceReference
"Treatment with ritanserin appeared to be ineffective."2.67Serotonin function in panic disorder: a double blind placebo controlled study with fluvoxamine and ritanserin. ( Den Boer, JA; Westenberg, HG, 1990)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leysen, JE1
Schotte, A1
Den Boer, JA1
Westenberg, HG1
Hoppenbrowers, ML1
Gelders, Y1
Vanden Bussche, G1
Janssen, PA1
Klieser, E1
Strauss, WH1

Reviews

2 reviews available for ritanserin and Mental Disorders

ArticleYear
Role and localization of serotonin-5HT2 receptors.
    Progress in histochemistry and cytochemistry, 1992, Volume: 26, Issue:1-4

    Topics: Animals; Blood Platelets; Brain Chemistry; Humans; Mental Disorders; Muscle, Smooth; Neurons; Organ

1992
Ritanserin (R 55667) an original thymosthenic.
    Bollettino chimico farmaceutico, 1986, Volume: 125, Issue:12

    Topics: Humans; Mental Disorders; Piperidines; Ritanserin; Serotonin Antagonists

1986

Trials

2 trials available for ritanserin and Mental Disorders

ArticleYear
Serotonin function in panic disorder: a double blind placebo controlled study with fluvoxamine and ritanserin.
    Psychopharmacology, 1990, Volume: 102, Issue:1

    Topics: Adult; beta-Endorphin; Blood Platelets; Double-Blind Method; Fear; Female; Fluvoxamine; Humans; Hydr

1990
The relevance of pharmacological studies to sleep research in psychiatry.
    Pharmacopsychiatry, 1988, Volume: 21, Issue:1

    Topics: Clinical Trials as Topic; Humans; Mental Disorders; Piperidines; Ritanserin; Serotonin Antagonists;

1988

Other Studies

1 other study available for ritanserin and Mental Disorders

ArticleYear
Study to establish the indication for the selective S2 antagonist ritanserin.
    Pharmacopsychiatry, 1988, Volume: 21, Issue:6

    Topics: Adult; Depressive Disorder; Female; Humans; Male; Mental Disorders; Middle Aged; Piperidines; Psychi

1988