Page last updated: 2024-11-03

ritanserin and Lung Neoplasms

ritanserin has been researched along with Lung Neoplasms in 3 studies

Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.

Lung Neoplasms: Tumors or cancer of the LUNG.

Research Excerpts

ExcerptRelevanceReference
"Ritanserin was tested in the clinic as a serotonin receptor inverse agonist but recently emerged as a novel kinase inhibitor with potential applications in cancer."1.48Chemoproteomic Discovery of a Ritanserin-Targeted Kinase Network Mediating Apoptotic Cell Death of Lung Tumor Cells. ( Borne, AL; Campbell, ST; Franks, CE; Hsu, KL; Shin, M; Zhang, L, 2018)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Zhou, D1
Liu, T1
Rao, X1
Jie, X1
Chen, Y1
Wu, Z1
Deng, H1
Zhang, D1
Wang, J2
Wu, G1
Kovalenko, A1
Sanin, A1
Kosmas, K1
Zhang, L2
Akl, EW1
Giannikou, K1
Probst, CK1
Hougard, TR1
Rue, RW1
Krymskaya, VP1
Asara, JM1
Lam, HC1
Kwiatkowski, DJ1
Henske, EP1
Filippakis, H1
Campbell, ST1
Franks, CE1
Borne, AL1
Shin, M1
Hsu, KL1

Other Studies

3 other studies available for ritanserin and Lung Neoplasms

ArticleYear
Targeting diacylglycerol kinase α impairs lung tumorigenesis by inhibiting cyclin D3.
    Thoracic cancer, 2023, Volume: 14, Issue:13

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D3; Diacylgly

2023
Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex.
    Cancer research, 2021, 04-15, Volume: 81, Issue:8

    Topics: Angiolipoma; Animals; Autophagy; Cell Proliferation; Chloroquine; Diacylglycerol Kinase; Down-Regula

2021
Chemoproteomic Discovery of a Ritanserin-Targeted Kinase Network Mediating Apoptotic Cell Death of Lung Tumor Cells.
    Molecular pharmacology, 2018, Volume: 94, Issue:5

    Topics: Amino Acid Sequence; Apoptosis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Line, Tu

2018