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ritanserin and Liver Cirrhosis, Biliary

ritanserin has been researched along with Liver Cirrhosis, Biliary in 1 studies

Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.

Liver Cirrhosis, Biliary: FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.

Research Excerpts

ExcerptRelevanceReference
"Eleven dogs with secondary biliary cirrhosis and portal hypertension due to chronic bile duct ligation were evaluated."1.28Serotonin blockade in conscious, unrestrained cirrhotic dogs with portal hypertension. ( Huet, PM; Mastaï, R; Rocheleau, B, 1989)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mastaï, R1
Rocheleau, B1
Huet, PM1

Other Studies

1 other study available for ritanserin and Liver Cirrhosis, Biliary

ArticleYear
Serotonin blockade in conscious, unrestrained cirrhotic dogs with portal hypertension.
    Hepatology (Baltimore, Md.), 1989, Volume: 9, Issue:2

    Topics: Animals; Blood Pressure; Cardiac Output; Common Bile Duct; Dogs; Female; Heart Rate; Hypertension, P

1989