ritanserin has been researched along with Leukoencephalopathy, Progressive Multifocal in 3 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
Leukoencephalopathy, Progressive Multifocal: An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
O'Hara, BA | 2 |
Gee, GV | 1 |
Atwood, WJ | 2 |
Haley, SA | 1 |
Loignon, M | 1 |
Toma, E | 1 |
Schaumburg, C | 1 |
Lane, TE | 1 |
1 review available for ritanserin and Leukoencephalopathy, Progressive Multifocal
Article | Year |
---|---|
Treatment options for progressive multifocal leukoencephalopathy in HIV-infected persons: current status and future directions.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Coinfection; Cy | 2016 |
2 other studies available for ritanserin and Leukoencephalopathy, Progressive Multifocal
Article | Year |
---|---|
Susceptibility of Primary Human Choroid Plexus Epithelial Cells and Meningeal Cells to Infection by JC Virus.
Topics: Cell Line; Choroid Plexus; Epithelial Cells; Humans; JC Virus; Leukoencephalopathy, Progressive Mult | 2018 |
Human embryonic stem cell-derived oligodendrocyte progenitor cells express the serotonin receptor and are susceptible to JC virus infection.
Topics: Antibodies, Monoclonal; Antigens; Biomarkers; Cell Line; Embryonic Stem Cells; Fetus; Humans; JC Vir | 2008 |