ritanserin has been researched along with Hypertension, Portal in 6 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven dogs with secondary biliary cirrhosis and portal hypertension due to chronic bile duct ligation were evaluated." | 1.28 | Serotonin blockade in conscious, unrestrained cirrhotic dogs with portal hypertension. ( Huet, PM; Mastaï, R; Rocheleau, B, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ladero Quesada, JM | 1 |
| Díez Ordóñez, S | 1 |
| Gallego Beuter, JJ | 1 |
| Hernández Lezana, A | 1 |
| Herraiz Serrano, ML | 1 |
| Díaz-Rubio García, M | 1 |
| Fernández, M | 2 |
| Pizcueta, P | 1 |
| García-Pagán, JC | 1 |
| Feu, F | 1 |
| Cirera, I | 1 |
| Bosch, J | 2 |
| Rodés, J | 2 |
| Pomier-Layrargues, G | 1 |
| Giroux, L | 2 |
| Rocheleau, B | 2 |
| Huet, PM | 3 |
| Nevens, F | 1 |
| Pizcueta, MP | 1 |
| Mastai, R | 2 |
| Semret, M | 1 |
6 other studies available for ritanserin and Hypertension, Portal
| Article | Year |
|---|---|
[Addition of ritanserin to the treatment with propranolol in cirrhotic patients: effects on portal pressure].
Topics: Adult; Aged; Drug Therapy, Combination; Humans; Hypertension, Portal; Middle Aged; Propranolol; Rita | 1994 |
Effects of ritanserin, a selective and specific S2-serotonergic antagonist, on portal pressure and splanchnic hemodynamics in rats with long-term bile duct ligation.
Topics: Animals; Bile Ducts; Blood Pressure; Hemodynamics; Hypertension, Portal; Ligation; Male; Portal Syst | 1993 |
Combined treatment of portal hypertension with ritanserin and propranolol in conscious and unrestrained cirrhotic rats.
Topics: Animals; Consciousness; Drug Therapy, Combination; Hemodynamics; Hypertension, Portal; Liver Cirrhos | 1992 |
Effects of ritanserin, a selective and specific S2-serotonergic antagonist, on portal pressure and splanchnic hemodynamics in portal hypertensive rats.
Topics: Animals; Blood Pressure; Hemodynamics; Hypertension, Portal; Male; Portal System; Rats; Rats, Inbred | 1991 |
Ritanserin decreases portal pressure in conscious and unrestrained cirrhotic rats.
Topics: Animals; Consciousness; Depression, Chemical; Hemodynamics; Hypertension, Portal; Liver Cirrhosis, E | 1990 |
Serotonin blockade in conscious, unrestrained cirrhotic dogs with portal hypertension.
Topics: Animals; Blood Pressure; Cardiac Output; Common Bile Duct; Dogs; Female; Heart Rate; Hypertension, P | 1989 |