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ritanserin and Hypercapnia

ritanserin has been researched along with Hypercapnia in 2 studies

Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.

Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.

Research Excerpts

ExcerptRelevanceReference
"To elucidate the role of serotonin in the maintenance of normal breathing and upper airway (UA) patency in obesity, we studied the effects of systemic administration of ritanserin, a serotonin (5-HT) 2A and 2C receptor antagonist, on ventilation (V E) during room air breathing and during hypoxic (10% O2) and hypercapnic (4% CO2) ventilatory challenges in awake young (6-8 wk) and older (7-8 mo) obese and lean Zucker (Z) rats."3.71Serotonergic modulation of ventilation and upper airway stability in obese Zucker rats. ( Farkas, GA; Krasney, JA; Lee, SD; Magalang, UJ; Nakano, H, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Negri, L1
Lattanzi, R1
Tabacco, F1
Melchiorri, P1
Nakano, H1
Magalang, UJ1
Lee, SD1
Krasney, JA1
Farkas, GA1

Other Studies

2 other studies available for ritanserin and Hypercapnia

ArticleYear
Respiratory and cardiovascular effects of the mu-opioid receptor agonist [Lys7]dermorphin in awake rats.
    British journal of pharmacology, 1998, Volume: 124, Issue:2

    Topics: Analgesia; Animals; Blood Pressure; Hypercapnia; Injections, Intravenous; Injections, Intraventricul

1998
Serotonergic modulation of ventilation and upper airway stability in obese Zucker rats.
    American journal of respiratory and critical care medicine, 2001, Volume: 163, Issue:5

    Topics: Age Factors; Analysis of Variance; Animals; Hypercapnia; Hyperoxia; Linear Models; Obesity; Plethysm

2001