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ritanserin and Dyskinesia, Drug-Induced

ritanserin has been researched along with Dyskinesia, Drug-Induced in 3 studies

Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.

Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)

Research Excerpts

ExcerptRelevanceReference
"Ritanserin pretreatment blunted systemic SKF 82958-induced hyperlocomotion and returned intrastriatal D1-mediated hyperactivity to sham lesion levels."1.32Intrastriatal serotonin 5-HT2 receptors mediate dopamine D1-induced hyperlocomotion in 6-hydroxydopamine-lesioned rats. ( Bishop, C; Kamdar, DP; Walker, PD, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bishop, C1
Kamdar, DP1
Walker, PD1
Marchese, G1
Bartholini, F1
Ruiu, S1
Casti, P1
Casu, GL1
Pani, L1
Maertens de Noordhout, A1
Delwaide, PJ1

Other Studies

3 other studies available for ritanserin and Dyskinesia, Drug-Induced

ArticleYear
Intrastriatal serotonin 5-HT2 receptors mediate dopamine D1-induced hyperlocomotion in 6-hydroxydopamine-lesioned rats.
    Synapse (New York, N.Y.), 2003, Volume: 50, Issue:2

    Topics: Animals; Benzazepines; Denervation; Dopamine; Dopamine Agonists; Drug Interactions; Dyskinesia, Drug

2003
Ritanserin counteracts both rat vacuous chewing movements and nigro-striatal tyrosine hydroxylase-immunostaining alterations induced by haloperidol.
    European journal of pharmacology, 2004, Jan-01, Volume: 483, Issue:1

    Topics: Animals; Antipsychotic Agents; Cell Size; Dyskinesia, Drug-Induced; Haloperidol; Immunohistochemistr

2004
Open pilot trial of ritanserin in parkinsonism.
    Clinical neuropharmacology, 1986, Volume: 9, Issue:5

    Topics: Aged; Antiparkinson Agents; Dyskinesia, Drug-Induced; Humans; Levodopa; Parkinson Disease; Pilot Pro

1986