ritanserin has been researched along with Depression, Endogenous in 10 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of pretreatment with ritanserin, a potent and selective serotonin-S2 (5-HT2) receptor antagonist, on the prolactin (PRL) response to electroconvulsive therapy (ECT) was studied in seven female patients suffering from major depressive disorder." | 3.68 | Ritanserin, a 5-HT2 receptor antagonist, does not modify ECT-induced prolactin release. ( Markianos, M; Papadimitriou, G; Papakostas, Y; Stefanis, C, 1990) |
| "Ritanserin treatment was very well tolerated; no serious adverse experiences were reported." | 2.67 | 5-HT2 receptor antagonism in dysthymic disorder: a double-blind placebo-controlled study with ritanserin. ( Bersani, G; Ciani, N; Grispini, A; Marini, S; Pasini, A; Pozzi, F, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kubera, M | 1 |
| Maes, M | 1 |
| Kenis, G | 1 |
| Kim, YK | 1 |
| LasoĊ, W | 1 |
| Lapierre, YD | 2 |
| Bakish, D | 1 |
| Weinstein, R | 1 |
| Klein, J | 1 |
| Wiens, A | 1 |
| Jones, B | 1 |
| Horn, E | 1 |
| Browne, M | 1 |
| Bourget, D | 1 |
| Blanchard, A | 1 |
| Staner, L | 1 |
| Kempenaers, C | 1 |
| Simonnet, MP | 1 |
| Fransolet, L | 1 |
| Mendlewicz, J | 1 |
| da Roza Davis, JM | 1 |
| Sharpley, AL | 1 |
| Solomon, RA | 1 |
| Cowen, PJ | 1 |
| Bersani, G | 1 |
| Pozzi, F | 1 |
| Marini, S | 1 |
| Grispini, A | 1 |
| Pasini, A | 1 |
| Ciani, N | 1 |
| Papakostas, Y | 1 |
| Markianos, M | 1 |
| Papadimitriou, G | 1 |
| Stefanis, C | 1 |
| Janssen, PA | 1 |
| Paiva, T | 1 |
| Arriaga, F | 1 |
| Wauquier, A | 1 |
| Lara, E | 1 |
| Largo, R | 1 |
| Leitao, JN | 1 |
| Klieser, E | 1 |
| Strauss, WH | 1 |
1 review available for ritanserin and Depression, Endogenous
| Article | Year |
|---|---|
Pharmacological therapy of dysthymia.
Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Benzamides; Benzodiazepines; Depressive Disorde | 1994 |
5 trials available for ritanserin and Depression, Endogenous
| Article | Year |
|---|---|
Ritanserin, imipramine, and placebo in the treatment of dysthymic disorder.
Topics: Adult; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Psychiatric Statu | 1993 |
Sleep and 5-HT2 receptor sensitivity in recovered depressed patients.
Topics: Adult; Aged; Depressive Disorder; Double-Blind Method; Electroencephalography; Female; Humans; Male; | 1992 |
5-HT2 receptor antagonism in dysthymic disorder: a double-blind placebo-controlled study with ritanserin.
Topics: Adult; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Personality Inve | 1991 |
Does ritanserin, a potent serotonin-S2 antagonist, restore energetic functions during the night?
Topics: Clinical Trials as Topic; Depressive Disorder; Humans; Piperidines; Ritanserin; Schizophrenia; Serot | 1987 |
Effects of ritanserin on sleep disturbances of dysthymic patients.
Topics: Adult; Depressive Disorder; Female; Humans; Male; Middle Aged; Piperidines; Psychiatric Status Ratin | 1988 |
4 other studies available for ritanserin and Depression, Endogenous
| Article | Year |
|---|---|
Effects of serotonin and serotonergic agonists and antagonists on the production of tumor necrosis factor alpha and interleukin-6.
Topics: Adult; Depressive Disorder; Dose-Response Relationship, Drug; Female; Fenclonine; Humans; Immunocomp | 2005 |
5-HT2 receptor antagonism and slow-wave sleep in major depression.
Topics: Adult; Depressive Disorder; Female; Humans; Male; Middle Aged; Placebos; Ritanserin; Serotonin Antag | 1992 |
Ritanserin, a 5-HT2 receptor antagonist, does not modify ECT-induced prolactin release.
Topics: Aged; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Middle Aged; Piperidines; Prol | 1990 |
Study to establish the indication for the selective S2 antagonist ritanserin.
Topics: Adult; Depressive Disorder; Female; Humans; Male; Mental Disorders; Middle Aged; Piperidines; Psychi | 1988 |