ritanserin has been researched along with Cocaine Abuse in 4 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ago, Y | 1 |
| Nakamura, S | 1 |
| Baba, A | 1 |
| Matsuda, T | 1 |
| Robbins, SJ | 2 |
| Ehrman, RN | 2 |
| Childress, AR | 1 |
| Cornish, JW | 2 |
| O'Brien, CP | 2 |
| Schenk, S | 1 |
| Maany, I | 1 |
| Fudala, PJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ritanserin in Treatment of Cocaine Dependence[NCT00000187] | Phase 2 | 80 participants (Actual) | Interventional | 1992-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ritanserin and Cocaine Abuse
| Article | Year |
|---|---|
Neuropsychotoxicity of abused drugs: effects of serotonin receptor ligands on methamphetamine- and cocaine-induced behavioral sensitization in mice.
Topics: Amphetamine-Related Disorders; Animals; Behavior, Animal; Brain; Bridged Bicyclo Compounds, Heterocy | 2008 |
1 trial available for ritanserin and Cocaine Abuse
| Article | Year |
|---|---|
A randomized, double-blind, placebo-controlled study of ritanserin pharmacotherapy for cocaine dependence.
Topics: Adult; Affect; Analysis of Variance; Anti-Anxiety Agents; Behavior, Addictive; Cocaine-Related Disor | 2001 |
2 other studies available for ritanserin and Cocaine Abuse
| Article | Year |
|---|---|
Mood state and recent cocaine use are not associated with levels of cocaine cue reactivity.
Topics: Adult; Affect; Arousal; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Cues; Drug Administration | 2000 |
Effects of the serotonin 5-HT(2) antagonist, ritanserin, and the serotonin 5-HT(1A) antagonist, WAY 100635, on cocaine-seeking in rats.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Mal | 2000 |