ritanserin has been researched along with Chemical Dependence in 5 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Currently, a full clinical development program of ritanserin in cocaine and alcohol abuse is ongoing." | 6.17 | Addiction and the potential for therapeutic drug development. ( Janssen, PA, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peng, Y | 1 |
| McCorvy, JD | 1 |
| Harpsøe, K | 1 |
| Lansu, K | 1 |
| Yuan, S | 1 |
| Popov, P | 1 |
| Qu, L | 1 |
| Pu, M | 1 |
| Che, T | 1 |
| Nikolajsen, LF | 1 |
| Huang, XP | 1 |
| Wu, Y | 1 |
| Shen, L | 1 |
| Bjørn-Yoshimoto, WE | 1 |
| Ding, K | 1 |
| Wacker, D | 1 |
| Han, GW | 1 |
| Cheng, J | 1 |
| Katritch, V | 1 |
| Jensen, AA | 1 |
| Hanson, MA | 1 |
| Zhao, S | 1 |
| Gloriam, DE | 1 |
| Roth, BL | 1 |
| Stevens, RC | 1 |
| Liu, ZJ | 1 |
| Janssen, PA | 2 |
| Johnson, BA | 1 |
| Chen, YR | 1 |
| Swann, AC | 1 |
| Schmitz, J | 1 |
| Lesser, J | 1 |
| Ruiz, P | 1 |
| Johnson, P | 1 |
| Clyde, C | 1 |
| Meert, T | 1 |
| Clincke, G | 1 |
| Meert, TF | 1 |
| Awouters, F | 1 |
| Niemegeers, CJ | 1 |
| Schellekens, KH | 1 |
1 review available for ritanserin and Chemical Dependence
| Article | Year |
|---|---|
Addiction and the potential for therapeutic drug development.
Topics: Alcoholism; Animals; Cocaine; Disease Models, Animal; Double-Blind Method; Humans; Research Design; | 1994 |
2 trials available for ritanserin and Chemical Dependence
| Article | Year |
|---|---|
Addiction and the potential for therapeutic drug development.
Topics: Alcoholism; Animals; Cocaine; Disease Models, Animal; Double-Blind Method; Humans; Research Design; | 1994 |
Ritanserin in the treatment of cocaine dependence.
Topics: Adult; Cocaine; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Ritanserin; Serotonin | 1997 |
3 other studies available for ritanserin and Chemical Dependence
| Article | Year |
|---|---|
5-HT
Topics: Ergotamine; HEK293 Cells; Humans; Obesity; Protein Domains; Receptor, Serotonin, 5-HT2C; Ritanserin; | 2018 |
Evidence for a possible role of the 5-HT2 antagonist ritanserin in drug abuse.
Topics: Alcoholic Intoxication; Animals; Cocaine; Fentanyl; Lysergic Acid Diethylamide; Motor Activity; Rats | 1992 |
Ritanserin reduces abuse of alcohol, cocaine, and fentanyl in rats.
Topics: Animals; Cocaine; Drinking; Ethanol; Fentanyl; Male; Rats; Rats, Inbred Strains; Ritanserin; Substan | 1991 |