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ritanserin and Chemical Dependence

ritanserin has been researched along with Chemical Dependence in 5 studies

Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.

Research Excerpts

ExcerptRelevanceReference
" Currently, a full clinical development program of ritanserin in cocaine and alcohol abuse is ongoing."6.17Addiction and the potential for therapeutic drug development. ( Janssen, PA, 1994)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Peng, Y1
McCorvy, JD1
Harpsøe, K1
Lansu, K1
Yuan, S1
Popov, P1
Qu, L1
Pu, M1
Che, T1
Nikolajsen, LF1
Huang, XP1
Wu, Y1
Shen, L1
Bjørn-Yoshimoto, WE1
Ding, K1
Wacker, D1
Han, GW1
Cheng, J1
Katritch, V1
Jensen, AA1
Hanson, MA1
Zhao, S1
Gloriam, DE1
Roth, BL1
Stevens, RC1
Liu, ZJ1
Janssen, PA2
Johnson, BA1
Chen, YR1
Swann, AC1
Schmitz, J1
Lesser, J1
Ruiz, P1
Johnson, P1
Clyde, C1
Meert, T1
Clincke, G1
Meert, TF1
Awouters, F1
Niemegeers, CJ1
Schellekens, KH1

Reviews

1 review available for ritanserin and Chemical Dependence

ArticleYear
Addiction and the potential for therapeutic drug development.
    EXS, 1994, Volume: 71

    Topics: Alcoholism; Animals; Cocaine; Disease Models, Animal; Double-Blind Method; Humans; Research Design;

1994

Trials

2 trials available for ritanserin and Chemical Dependence

ArticleYear
Addiction and the potential for therapeutic drug development.
    EXS, 1994, Volume: 71

    Topics: Alcoholism; Animals; Cocaine; Disease Models, Animal; Double-Blind Method; Humans; Research Design;

1994
Ritanserin in the treatment of cocaine dependence.
    Biological psychiatry, 1997, Nov-15, Volume: 42, Issue:10

    Topics: Adult; Cocaine; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Ritanserin; Serotonin

1997

Other Studies

3 other studies available for ritanserin and Chemical Dependence

ArticleYear
5-HT
    Cell, 2018, 02-08, Volume: 172, Issue:4

    Topics: Ergotamine; HEK293 Cells; Humans; Obesity; Protein Domains; Receptor, Serotonin, 5-HT2C; Ritanserin;

2018
Evidence for a possible role of the 5-HT2 antagonist ritanserin in drug abuse.
    Annals of the New York Academy of Sciences, 1992, Jun-28, Volume: 654

    Topics: Alcoholic Intoxication; Animals; Cocaine; Fentanyl; Lysergic Acid Diethylamide; Motor Activity; Rats

1992
Ritanserin reduces abuse of alcohol, cocaine, and fentanyl in rats.
    Pharmacopsychiatry, 1991, Volume: 24, Issue:5

    Topics: Animals; Cocaine; Drinking; Ethanol; Fentanyl; Male; Rats; Rats, Inbred Strains; Ritanserin; Substan

1991