Page last updated: 2024-11-03

ritanserin and Bipolar Disorder

ritanserin has been researched along with Bipolar Disorder in 2 studies

Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of ritanserin to obtain a better improvement in patients with mania seems to support the 5-HT hypothesis of bipolar disorder."5.10Ritanserin as an adjunct to lithium and haloperidol for the treatment of medication-naive patients with acute mania: a double blind and placebo controlled trial. ( Akhondzadeh, S; Amini, H; Mohajari, H; Reza Mohammadi, M, 2003)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akhondzadeh, S1
Mohajari, H1
Reza Mohammadi, M1
Amini, H1
Miller, CH1
Hummer, M1
Pycha, R1
Fleischhacker, WW1

Trials

1 trial available for ritanserin and Bipolar Disorder

ArticleYear
Ritanserin as an adjunct to lithium and haloperidol for the treatment of medication-naive patients with acute mania: a double blind and placebo controlled trial.
    BMC psychiatry, 2003, Jun-19, Volume: 3

    Topics: Acute Disease; Adult; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Haloperidol;

2003

Other Studies

1 other study available for ritanserin and Bipolar Disorder

ArticleYear
The effect of ritanserin on treatment-resistant neuroleptic induced akathisia: case reports.
    Progress in neuro-psychopharmacology & biological psychiatry, 1992, Volume: 16, Issue:2

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Male; Psycho

1992