ritanserin has been researched along with Anorexia in 4 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When ritanserin was tested for its ability to block the anorectic effect of exogenous 5HT, it inhibited the effect of intraperitoneal (IP) 5HT, but proved to be completely inactive versus the effect of 5HT injected into the hypothalamic paraventricular nucleus, which is highly sensitive to this effect of 5HT." | 5.27 | Effect of the 5HT2 antagonist ritanserin on food intake and on 5HT-induced anorexia in the rat. ( Marini, S; Massi, M, 1987) |
| "When ritanserin was tested for its ability to block the anorectic effect of exogenous 5HT, it inhibited the effect of intraperitoneal (IP) 5HT, but proved to be completely inactive versus the effect of 5HT injected into the hypothalamic paraventricular nucleus, which is highly sensitive to this effect of 5HT." | 1.27 | Effect of the 5HT2 antagonist ritanserin on food intake and on 5HT-induced anorexia in the rat. ( Marini, S; Massi, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| von Meyenburg, C | 1 |
| Langhans, W | 1 |
| Hrupka, BJ | 1 |
| Grignaschi, G | 1 |
| Mantelli, B | 1 |
| Samanin, R | 1 |
| Raghavendra, V | 1 |
| Kulkarni, SK | 1 |
| Massi, M | 1 |
| Marini, S | 1 |
4 other studies available for ritanserin and Anorexia
| Article | Year |
|---|---|
Evidence that the anorexia induced by lipopolysaccharide is mediated by the 5-HT2C receptor.
Topics: Adrenergic beta-Antagonists; Aminopyridines; Animals; Anorexia; Dopamine Antagonists; Dose-Response | 2003 |
The hypophagic effect of restraint stress in rats can be mediated by 5-HT2 receptors in the paraventricular nucleus of the hypothalamus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amidines; Animals; Anorexia; Anorexia Nervosa; Disease Model | 1993 |
Melatonin reversal of DOI-induced hypophagia in rats; possible mechanism by suppressing 5-HT(2A) receptor-mediated activation of HPA axis.
Topics: Adrenal Glands; Amphetamines; Animals; Anorexia; Ascorbic Acid; Exploratory Behavior; Feeding Behavi | 2000 |
Effect of the 5HT2 antagonist ritanserin on food intake and on 5HT-induced anorexia in the rat.
Topics: Animals; Anorexia; Brain; Drinking Behavior; Feeding and Eating Disorders; Feeding Behavior; Food De | 1987 |