ritanserin has been researched along with Anesthesia Related Hyperthermia in 4 studies
Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.
| Excerpt | Relevance | Reference |
|---|---|---|
| "During halothane-induced malignant hyperthermia (MH), plasma levels of serotonin (5-hydroxytryptamine, 5-HT) increase in pigs." | 1.29 | Lack of prophylactic or therapeutic efficacy of 5-HT2A receptor antagonists in halothane-induced porcine malignant hyperthermia. ( Gerdes, C; Löscher, W; Richter, A, 1994) |
| "Ritanserin did not cause any significant changes of IP levels compared to the basal concentrations in MHS and MHN pigs." | 1.29 | Effects of the 5-HT2 receptor antagonist ritanserin on halothane-induced increase of inositol phosphates in porcine malignant hyperthermia. ( Löscher, W; Richter, A; Scholz, J; Tonner, PH; Wappler, F, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Löscher, W | 2 |
| Gerdes, C | 1 |
| Richter, A | 3 |
| Scholz, J | 3 |
| Tonner, PH | 1 |
| Wappler, F | 3 |
| Oppermann, S | 1 |
| von Richthofen, V | 1 |
| Steinfath, M | 2 |
| Schulte am Esch, J | 2 |
| Fiege, M | 1 |
| Weisshorn, R | 1 |
1 trial available for ritanserin and Anesthesia Related Hyperthermia
| Article | Year |
|---|---|
Ritanserin attenuates the in vitro effects of the 5-HT2 receptor agonist DOI on skeletal muscles from malignant hyperthermia-susceptible patients.
Topics: Adolescent; Adult; Amphetamines; Female; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; | 1997 |
3 other studies available for ritanserin and Anesthesia Related Hyperthermia
| Article | Year |
|---|---|
Lack of prophylactic or therapeutic efficacy of 5-HT2A receptor antagonists in halothane-induced porcine malignant hyperthermia.
Topics: Animals; Blood Pressure; Body Temperature; Dantrolene; Female; Halothane; Heart Rate; Ketanserin; Ma | 1994 |
Effects of the 5-HT2 receptor antagonist ritanserin on halothane-induced increase of inositol phosphates in porcine malignant hyperthermia.
Topics: Anesthetics, Inhalation; Animals; Halothane; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mali | 1996 |
5-HT2 receptor antagonist-mediated inhibition of halothane-induced contractures in skeletal muscle specimens from malignant hyperthermia susceptible patients.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Caffeine; Child; Dose-Response Relationship, Drug; Drug | 1999 |