Page last updated: 2024-11-03

risperidone and Syndrome

risperidone has been researched along with Syndrome in 40 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"Six of 13 outpatients with schizophrenia who participated in a ten-week open trial of risperidone had an initial good response to the medication followed by development of intolerable affect, including feelings of agitation and depression and periods of crying and insomnia."9.08A syndrome of increased affect in response to risperidone among patients with schizophrenia. ( Ashleigh, EA; Larsen, PD, 1998)
"A patient with comorbid intellectual disability, catatonic schizophrenia, and recurrent oneiroid state of consciousness improved on long-acting risperidone and remains well at the three-year follow-up."7.81Effectiveness of long-acting risperidone in a patient with comorbid intellectual disability, catatonic schizophrenia, and oneiroid syndrome. ( Alessi, MC; Angeletti, G; Callovini, G; Criscuolo, S; Del Casale, A; Ferri, VR; Girardi, P; Janiri, D; Kotzalidis, GD; Massolo, AC; Rapinesi, C; Serata, D, 2015)
"To report a case of risperidone-induced Pisa syndrome in a patient with multiple sclerosis (MS) that resolved with lurasidone, recurred with chlorpromazine, and was complicated by possible drug-drug interactions."7.79Risperidone-induced Pisa syndrome in MS: resolution with lurasidone and recurrence with Chlorpromazine. ( Diefenderfer, LA; Iuppa, CA, 2013)
"Long-acting injectable (LAI) formulations of antipsychotics are valuable treatment alternatives for patients with psychotic disorders, and understanding their safe use is critical."5.37Are the long-acting intramuscular formulations of risperidone or paliperidone palmitate associated with post-injection delirium/sedation syndrome? An assessment of safety databases. ( Alphs, L; Gopal, S; Karcher, K; Kent, J; Kushner, S; Nuamah, I; Singh, J; Sliwa, JK, 2011)
"Six of 13 outpatients with schizophrenia who participated in a ten-week open trial of risperidone had an initial good response to the medication followed by development of intolerable affect, including feelings of agitation and depression and periods of crying and insomnia."5.08A syndrome of increased affect in response to risperidone among patients with schizophrenia. ( Ashleigh, EA; Larsen, PD, 1998)
"A patient with comorbid intellectual disability, catatonic schizophrenia, and recurrent oneiroid state of consciousness improved on long-acting risperidone and remains well at the three-year follow-up."3.81Effectiveness of long-acting risperidone in a patient with comorbid intellectual disability, catatonic schizophrenia, and oneiroid syndrome. ( Alessi, MC; Angeletti, G; Callovini, G; Criscuolo, S; Del Casale, A; Ferri, VR; Girardi, P; Janiri, D; Kotzalidis, GD; Massolo, AC; Rapinesi, C; Serata, D, 2015)
"To report a case of risperidone-induced Pisa syndrome in a patient with multiple sclerosis (MS) that resolved with lurasidone, recurred with chlorpromazine, and was complicated by possible drug-drug interactions."3.79Risperidone-induced Pisa syndrome in MS: resolution with lurasidone and recurrence with Chlorpromazine. ( Diefenderfer, LA; Iuppa, CA, 2013)
"Both risperidone and clozapine have been shown to be effective against negative symptoms."3.78New pharmacotherapeutic modalities for negative symptoms in psychosis. ( Lindenmayer, JP, 1995)
"This study evaluates the relationship between plasma homovanillic acid (pHVA) levels, which have been used to study the role of central dopamine in schizophrenia, and the positive/negative syndrome in first episode schizophrenic patients before and after antipsychotic treatment."3.75Plasma homovanillic acid differences in clinical subgroups of first episode schizophrenic patients. ( Baeza, I; Bernardo, M; Castro-Fornieles, J; de la Serna, E; Deulofeu, R; Goti, J; Salvà, J, 2009)
" A case of 'PANDAS' is presented to increase physician awareness of this disorder and to document effectiveness of risperidone in chorea and treatment-resistant disruptive behavior associated with this syndrome."3.70Risperidone in the treatment of choreiform movements and aggressiveness in a child with "PANDAS". ( Bhatara, VS; Kleinsasser, BJ; Misra, LK; Sanchez, JD, 1999)
"When the concepts of dementia praecox and schizophrenia were introduced by Kraepelin and Bleuler, emphasis was laid on the negative symptoms, regarded as fundamental."2.39Principal components and further possibilities with the PANSS. ( Lindström, E; von Knorring, L, 1995)
"Cotard syndrome was first described in 1880 by Jules Cotard as a novel subtype of anxious depression and is presently understood as a rare cluster of mood and psychotic symptoms centered on nihilistic delusions including the absence of organs and a perception of being dead."1.62Cotard Syndrome in an Adolescent With a First Episode of Psychosis. ( Boles, MK; Boyanchek, I; McGreal, AE, 2021)
"This short report provides guidance for antipsychotic medication dosing to improve early intervention outcomes."1.56Early behavioral and developmental interventions in ADNP-syndrome: A case report of SWI/SNF-related neurodevelopmental syndrome. ( Hopkin, R; Pedapati, E; Shillington, A; Suhrie, K, 2020)
"Pulmonary embolism was seen in our patient a week after starting risperidone."1.48Pseudo-Wellens' syndrome in pulmonary embolism. ( Basnyat, S; Bhattacharya, PT; Sedhai, YR, 2018)
"She also exhibited precocious puberty and growth hormone deficiency and required treatment for improving final height."1.40Endocrinological anomalies in a patient with 12q14 microdeletion syndrome. Completing phenotype of this exceptional short stature condition. ( Marco, FC; Nso-Roca, AP; Ricote, JM; Ruiz, MJ, 2014)
"Long-acting injectable (LAI) formulations of antipsychotics are valuable treatment alternatives for patients with psychotic disorders, and understanding their safe use is critical."1.37Are the long-acting intramuscular formulations of risperidone or paliperidone palmitate associated with post-injection delirium/sedation syndrome? An assessment of safety databases. ( Alphs, L; Gopal, S; Karcher, K; Kent, J; Kushner, S; Nuamah, I; Singh, J; Sliwa, JK, 2011)
" In the patient with laryngeal dystonia these symptoms appeared after restarting risperidone treatment, in the other patient after diminishing the dosage of risperidone and adding sertindole, and in the third patient the syndrome appeared after beginning ziprasidone."1.37Pisa syndrome and laryngeal dystonia induced by novel antipsychotics. ( Lerner, V; Miodownik, C; Witztum, E, 2011)
"Usher's syndrome is a genetic disorder that causes congenital sensorineural hearing loss, visual impairment due to progressive pigmentary retinopathy, and, often, vestibular dysfunction."1.31The relationship between Usher's syndrome and psychosis with Capgras syndrome. ( Medalia, A; Waldeck, T; Wyszynski, B, 2001)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (15.00)18.2507
2000's17 (42.50)29.6817
2010's14 (35.00)24.3611
2020's3 (7.50)2.80

Authors

AuthorsStudies
Shillington, A1
Pedapati, E1
Hopkin, R1
Suhrie, K1
Valadas, MTTRT1
Bravo, LEA1
McGreal, AE1
Boles, MK1
Boyanchek, I1
Kuppili, PP1
Gupta, R1
Pattanayak, RD1
Khandelwal, SK1
Sedhai, YR1
Basnyat, S1
Bhattacharya, PT1
Iuppa, CA1
Diefenderfer, LA1
Nso-Roca, AP1
Marco, FC1
Ricote, JM1
Ruiz, MJ1
Saddichha, S1
Talukdar, D1
Serata, D1
Rapinesi, C1
Kotzalidis, GD1
Alessi, MC1
Janiri, D1
Massolo, AC1
Ferri, VR1
Criscuolo, S1
Callovini, G1
Angeletti, G1
Girardi, P1
Del Casale, A1
Cordeiro, Q1
Zung, S1
Vallada, H1
Lamkin, S1
Buhl, D1
Pasini, A1
D'Agati, E1
Casarelli, L1
Curatolo, P1
Baeza, I1
Castro-Fornieles, J1
Deulofeu, R1
de la Serna, E1
Goti, J1
Salvà, J1
Bernardo, M1
Alphs, L1
Gopal, S1
Karcher, K1
Kent, J1
Sliwa, JK1
Kushner, S1
Nuamah, I1
Singh, J1
Danivas, V1
Behere, RV1
Varambally, S1
Rao, NP1
Venkatasubramanian, G1
Gangadhar, BN1
Chou, PH1
Lin, BT1
Lan, TH1
Chan, CH1
Schweitzer, I1
Miodownik, C1
Lerner, V1
Witztum, E1
Bonci, G1
Varghese, E1
Mahgoub, N1
Zugman, A1
Pan, PM1
Gadelha, A1
Mansur, RB1
Asevedo, E1
Cunha, GR1
Silva, PF1
Brietzke, E1
Bressan, RA1
Nakagawa, S1
Koyama, T1
Maeda, K1
Shirayama, Y1
Nukina, S1
Yoshioka, S1
Kawahara, R1
Eren, I1
Ozcankaya, R1
Altinyazar, V1
Mendhekar, DN1
Kozian, R1
Nishimura, K1
Mikami, Y1
Tsuchibuchi, S1
Horikawa, N1
Niederhofer, H1
Kessler, H1
Kraft, S1
Lindenmayer, JP1
von Knorring, L1
Lindström, E1
Ashleigh, EA1
Larsen, PD1
Schwartz, M1
Beny, A1
Sharf, B1
Kleinsasser, BJ1
Misra, LK1
Bhatara, VS1
Sanchez, JD1
Kornreich, C1
Dan, B1
Verbanck, P1
Pelc, I1
Kwak, YT1
Han, IW1
Baik, J1
Koo, MS1
Blanch, J1
Corbella, B1
García, F1
Parellada, E1
Gatell, JM1
Waldeck, T1
Wyszynski, B1
Medalia, A1
Harada, K1
Sasaki, N1
Ikeda, H1
Nakano, N1
Ozawa, H1
Saito, T1
Jagadheesan, K1
Nizamie, SH1
Hillert, A1
Maier, W1
Wetzel, H1
Benkert, O1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Open-label, Flexible-dose Adjunctive Bromocriptine for Patients With Schizophrenia and Impaired Glucose Tolerance[NCT03575000]Phase 420 participants (Anticipated)Interventional2023-11-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for risperidone and Syndrome

ArticleYear
[Extrapyramidal syndrome].
    Ryoikibetsu shokogun shirizu, 2003, Issue:38

    Topics: Acute Disease; Akathisia, Drug-Induced; Antipsychotic Agents; Basal Ganglia Diseases; Dibenzothiazep

2003
[Neuropsychiatric symptoms in Sotos syndrome. Case report and review of the literature].
    Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater, 2008, Volume: 22, Issue:1

    Topics: Adult; Antipsychotic Agents; Brain; Carbamazepine; Chromosome Deletion; Citalopram; Compulsive Behav

2008
New pharmacotherapeutic modalities for negative symptoms in psychosis.
    Acta psychiatrica Scandinavica. Supplementum, 1995, Volume: 388

    Topics: Affective Symptoms; Antipsychotic Agents; Clozapine; Humans; Isoxazoles; Piperidines; Psychiatric St

1995
Principal components and further possibilities with the PANSS.
    Acta psychiatrica Scandinavica. Supplementum, 1995, Volume: 388

    Topics: Affective Symptoms; Antipsychotic Agents; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating

1995

Trials

2 trials available for risperidone and Syndrome

ArticleYear
New pharmacotherapeutic modalities for negative symptoms in psychosis.
    Acta psychiatrica Scandinavica. Supplementum, 1995, Volume: 388

    Topics: Affective Symptoms; Antipsychotic Agents; Clozapine; Humans; Isoxazoles; Piperidines; Psychiatric St

1995
A syndrome of increased affect in response to risperidone among patients with schizophrenia.
    Psychiatric services (Washington, D.C.), 1998, Volume: 49, Issue:4

    Topics: Adult; Antipsychotic Agents; Anxiety; Disease Susceptibility; Follow-Up Studies; Humans; Male; Middl

1998

Other Studies

35 other studies available for risperidone and Syndrome

ArticleYear
Early behavioral and developmental interventions in ADNP-syndrome: A case report of SWI/SNF-related neurodevelopmental syndrome.
    Molecular genetics & genomic medicine, 2020, Volume: 8, Issue:6

    Topics: Antipsychotic Agents; Autism Spectrum Disorder; Behavioral Symptoms; Child, Preschool; Early Medical

2020
De Clérambault's syndrome revisited: a case report of Erotomania in a male.
    BMC psychiatry, 2020, 10-23, Volume: 20, Issue:1

    Topics: Aged; Aggression; Delusions; Female; Humans; Male; Middle Aged; Prognosis; Risperidone; Syndrome

2020
Cotard Syndrome in an Adolescent With a First Episode of Psychosis.
    Journal of psychiatric practice, 2021, 05-05, Volume: 27, Issue:3

    Topics: Adolescent; Antipsychotic Agents; Delusions; Electroconvulsive Therapy; Female; Humans; Psychotic Di

2021
Delusional denial of pregnancy: Unique presentation of Cotard's syndrome in a patient with schizophrenia.
    Asian journal of psychiatry, 2017, Volume: 30

    Topics: Adult; Antipsychotic Agents; Delusions; Denial, Psychological; Female; Humans; Pregnancy; Pregnancy

2017
Pseudo-Wellens' syndrome in pulmonary embolism.
    BMJ case reports, 2018, Dec-19, Volume: 11, Issue:1

    Topics: Antipsychotic Agents; Chest Pain; Coronary Stenosis; Electrocardiography; Humans; Male; Pulmonary Em

2018
Risperidone-induced Pisa syndrome in MS: resolution with lurasidone and recurrence with Chlorpromazine.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:9

    Topics: Adult; Antipsychotic Agents; Child Development Disorders, Pervasive; Chlorpromazine; Gait Ataxia; Hu

2013
Endocrinological anomalies in a patient with 12q14 microdeletion syndrome. Completing phenotype of this exceptional short stature condition.
    Journal of pediatric endocrinology & metabolism : JPEM, 2014, Volume: 27, Issue:5-6

    Topics: Antipsychotic Agents; Body Height; Child; Child Behavior Disorders; Chromosome Deletion; Dwarfism; E

2014
Serpentine tongue syndrome associated with risperidone long-acting injection treatment.
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:5

    Topics: Antipsychotic Agents; Humans; Male; Middle Aged; Movement Disorders; Risperidone; Syndrome; Tongue

2014
Effectiveness of long-acting risperidone in a patient with comorbid intellectual disability, catatonic schizophrenia, and oneiroid syndrome.
    International journal of psychiatry in medicine, 2015, Volume: 50, Issue:3

    Topics: Adult; Ambroxol; Antipsychotic Agents; Brain; Dreams; Follow-Up Studies; Humans; Intellectual Disabi

2015
Pisa syndrome induced by rapid increase and high dosage of risperidone.
    Arquivos de neuro-psiquiatria, 2008, Volume: 66, Issue:4

    Topics: Adolescent; Antipsychotic Agents; Dystonia; Humans; Male; Risperidone; Schizophrenia; Syndrome

2008
Extrapyramidal side effects: could you identify them in the emergency department?
    Journal of emergency nursing, 2009, Volume: 35, Issue:1

    Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Dopamine Antagonists; Dyskinesi

2009
Dose-dependent effect of risperidone treatment in a case of 22q13.3 deletion syndrome.
    Brain & development, 2010, Volume: 32, Issue:5

    Topics: Abnormalities, Multiple; Adolescent; Aggression; Animals; Antipsychotic Agents; Chromosome Deletion;

2010
Plasma homovanillic acid differences in clinical subgroups of first episode schizophrenic patients.
    Psychiatry research, 2009, Jul-30, Volume: 168, Issue:2

    Topics: Adult; Antipsychotic Agents; Dopamine; Female; Follow-Up Studies; Homovanillic Acid; Humans; Male; P

2009
Are the long-acting intramuscular formulations of risperidone or paliperidone palmitate associated with post-injection delirium/sedation syndrome? An assessment of safety databases.
    Current drug safety, 2011, Feb-01, Volume: 6, Issue:1

    Topics: Chemistry, Pharmaceutical; Clinical Trials as Topic; Conscious Sedation; Databases, Factual; Delayed

2011
Electroconvulsive therapy in the treatment of delirious mania: a report of 2 patients.
    The journal of ECT, 2010, Volume: 26, Issue:4

    Topics: Adolescent; Antimanic Agents; Bipolar Disorder; Catatonia; Delirium; Electroconvulsive Therapy; Fema

2010
Chronic Cotard's syndrome: recovery from 2 years' bed-ridden status.
    Psychiatry and clinical neurosciences, 2011, Volume: 65, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Chronic Disease; Delusions; Drug The

2011
Anticonvulsant hypersensitivity syndrome: a rare and serious complication.
    The Medical journal of Australia, 2011, Jun-06, Volume: 194, Issue:11

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Anticonvulsants; Antipsychotic Agents; Bipolar Di

2011
Pisa syndrome and laryngeal dystonia induced by novel antipsychotics.
    The Israel journal of psychiatry and related sciences, 2011, Volume: 48, Issue:3

    Topics: Adult; Antipsychotic Agents; Dystonia; Humans; Imidazoles; Indoles; Laryngeal Diseases; Male; Middle

2011
A case of Diogenes syndrome: clinical and ethical challenges.
    Journal of the American Geriatrics Society, 2012, Volume: 60, Issue:9

    Topics: Aged, 80 and over; Antihypertensive Agents; Antipsychotic Agents; Diagnosis, Differential; Female; G

2012
Brain tumor in a patient with attenuated psychosis syndrome.
    Schizophrenia research, 2013, Volume: 144, Issue:1-3

    Topics: Adolescent; Antipsychotic Agents; Brain Neoplasms; Cognitive Behavioral Therapy; Combined Modality T

2013
Charles Bonnet syndrome with visual hallucinations of childhood experience: successful treatment of 1 patient with risperidone.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:9

    Topics: Antipsychotic Agents; Cataract Extraction; Child; Diabetic Retinopathy; Female; Hallucinations; Huma

2003
Risperidone-induced rabbit syndrome in mood disorder.
    European psychiatry : the journal of the Association of European Psychiatrists, 2004, Volume: 19, Issue:7

    Topics: Antipsychotic Agents; Depressive Disorder, Major; Diagnosis, Differential; Hallucinations; Humans; M

2004
Rabbit syndrome induced by combined lithium and risperidone.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2005, Volume: 50, Issue:6

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Bipolar Disorder; Drug Therapy, Combination; Dy

2005
[Brief case report. Duloxetine in Cotard syndrome].
    Psychiatrische Praxis, 2005, Volume: 32, Issue:8

    Topics: Affective Disorders, Psychotic; Aged; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines;

2005
Pisa syndrome resolved after switching to olanzapine.
    The Journal of neuropsychiatry and clinical neurosciences, 2007,Spring, Volume: 19, Issue:2

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Diagnostic and Statistical Manual of Mental Disorders;

2007
Efficacy of risperidone treatment in Smith-Magenis syndrome (del 17 pll. 2).
    Psychiatria Danubina, 2007, Volume: 19, Issue:3

    Topics: Abnormalities, Multiple; Adolescent; Aggression; Antipsychotic Agents; Attention Deficit Disorder wi

2007
Risperidone-induced rabbit syndrome.
    The British journal of psychiatry : the journal of mental science, 1998, Volume: 173

    Topics: Aged; Antipsychotic Agents; Basal Ganglia Diseases; Female; Humans; Mouth Diseases; Risperidone; Syn

1998
Risperidone in the treatment of choreiform movements and aggressiveness in a child with "PANDAS".
    South Dakota journal of medicine, 1999, Volume: 52, Issue:9

    Topics: Aggression; Antipsychotic Agents; Autoimmune Diseases; Child; Child Behavior Disorders; Chorea; Huma

1999
Treating Charles Bonnet syndrome: understanding inconsistency.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:3

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Hallucinations; Haloperidol; Humans; Male; Psychotic

2000
Relation between cholinesterase inhibitor and Pisa syndrome.
    Lancet (London, England), 2000, Jun-24, Volume: 355, Issue:9222

    Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Donepezil; Dopamine Antagonists; Dys

2000
Manic syndrome associated with efavirenz overdose.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Jul-15, Volume: 33, Issue:2

    Topics: Adult; Alkynes; Anti-HIV Agents; Antipsychotic Agents; Benzoxazines; Bipolar Disorder; Cyclopropanes

2001
The relationship between Usher's syndrome and psychosis with Capgras syndrome.
    Psychiatry, 2001,Fall, Volume: 64, Issue:3

    Topics: Aged; Antipsychotic Agents; Capgras Syndrome; Diagnosis, Differential; Female; Hearing Loss, Sensori

2001
Risperidone-induced Pisa syndrome.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:2

    Topics: Adult; Antipsychotic Agents; Dystonia; Humans; Male; Risperidone; Schizophrenia; Syndrome

2002
Risperidone-induced Pisa syndrome.
    The Australian and New Zealand journal of psychiatry, 2002, Volume: 36, Issue:1

    Topics: Adult; Antipsychotic Agents; Dystonic Disorders; Female; Humans; Intellectual Disability; Posture; P

2002
Risperidone in the treatment of disorders with a combined psychotic and depressive syndrome--a functional approach.
    Pharmacopsychiatry, 1992, Volume: 25, Issue:5

    Topics: Adult; Aged; Antipsychotic Agents; Depressive Disorder; Female; Humans; Isoxazoles; Male; Middle Age

1992