Page last updated: 2024-11-03

risperidone and Sleep Initiation and Maintenance Disorders

risperidone has been researched along with Sleep Initiation and Maintenance Disorders in 16 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.

Research Excerpts

ExcerptRelevanceReference
" This 53-wk, Phase-III double-blind study was designed to assess the non-inferiority of PP to risperidone long-acting injectable (RIS-LAI) in schizophrenia treatment."9.16A randomized trial of paliperidone palmitate and risperidone long-acting injectable in schizophrenia. ( Eerdekens, M; Fleischhacker, WW; Gassmann-Mayer, C; Gopal, S; Hough, D; Lane, R; Lim, P; Remmerie, B, 2012)
"In this multicenter, double-blind, 16-week, placebo-controlled study conducted at 43 American sites from July 2006 to October 2007, patients with chronic, stable schizophrenia or schizoaffective disorder diagnosed with DSM-IV-TR were randomly assigned to receive aripiprazole (2-15 mg/d) or placebo in addition to a stable regimen of quetiapine (400-800 mg/d) or risperidone (4-8 mg/d)."9.14A multicenter, randomized, double-blind, placebo-controlled, 16-week study of adjunctive aripiprazole for schizophrenia or schizoaffective disorder inadequately treated with quetiapine or risperidone monotherapy. ( Assunção-Talbott, S; Carson, WH; Correll, CU; Goff, DC; Kane, JM; Kirkpatrick, B; Marder, SR; Pikalov, A; Sun, W; Vester-Blokland, E, 2009)
"The safety and efficacy of the first long-acting injectable atypical antipsychotic, risperidone, were assessed in stable patients with schizophrenia switched from oral antipsychotic medications."9.11Safety and efficacy of long-acting risperidone in schizophrenia: a 12-week, multicenter, open-label study in stable patients switched from typical and atypical oral antipsychotics. ( Berry, SA; Eerdekens, E; Eerdekens, M; Lindenmayer, JP, 2004)
" Thus, we compared ziprasidone and risperidone in patients with acute exacerbation of schizophrenia or schizoaffective disorder."9.11Efficacy and tolerability of ziprasidone versus risperidone in patients with acute exacerbation of schizophrenia or schizoaffective disorder: an 8-week, double-blind, multicenter trial. ( Addington, DE; Benattia, I; Dineen, M; Pantelis, C; Romano, SJ, 2004)
"The subjects were 20 outpatients with schizophrenia or schizoaffective disorder who were clinically stable on a regimen of clozapine at the time of screening."9.08Different side effect profiles of risperidone and clozapine in 20 outpatients with schizophrenia or schizoaffective disorder: a pilot study. ( Daniel, DG; Goldberg, TE; Kleinman, JE; Lubick, LJ; Pickar, D; Weinberger, DR; Williams, TS, 1996)
" This 53-wk, Phase-III double-blind study was designed to assess the non-inferiority of PP to risperidone long-acting injectable (RIS-LAI) in schizophrenia treatment."5.16A randomized trial of paliperidone palmitate and risperidone long-acting injectable in schizophrenia. ( Eerdekens, M; Fleischhacker, WW; Gassmann-Mayer, C; Gopal, S; Hough, D; Lane, R; Lim, P; Remmerie, B, 2012)
"In this multicenter, double-blind, 16-week, placebo-controlled study conducted at 43 American sites from July 2006 to October 2007, patients with chronic, stable schizophrenia or schizoaffective disorder diagnosed with DSM-IV-TR were randomly assigned to receive aripiprazole (2-15 mg/d) or placebo in addition to a stable regimen of quetiapine (400-800 mg/d) or risperidone (4-8 mg/d)."5.14A multicenter, randomized, double-blind, placebo-controlled, 16-week study of adjunctive aripiprazole for schizophrenia or schizoaffective disorder inadequately treated with quetiapine or risperidone monotherapy. ( Assunção-Talbott, S; Carson, WH; Correll, CU; Goff, DC; Kane, JM; Kirkpatrick, B; Marder, SR; Pikalov, A; Sun, W; Vester-Blokland, E, 2009)
"The safety and efficacy of the first long-acting injectable atypical antipsychotic, risperidone, were assessed in stable patients with schizophrenia switched from oral antipsychotic medications."5.11Safety and efficacy of long-acting risperidone in schizophrenia: a 12-week, multicenter, open-label study in stable patients switched from typical and atypical oral antipsychotics. ( Berry, SA; Eerdekens, E; Eerdekens, M; Lindenmayer, JP, 2004)
" Thus, we compared ziprasidone and risperidone in patients with acute exacerbation of schizophrenia or schizoaffective disorder."5.11Efficacy and tolerability of ziprasidone versus risperidone in patients with acute exacerbation of schizophrenia or schizoaffective disorder: an 8-week, double-blind, multicenter trial. ( Addington, DE; Benattia, I; Dineen, M; Pantelis, C; Romano, SJ, 2004)
"The subjects were 20 outpatients with schizophrenia or schizoaffective disorder who were clinically stable on a regimen of clozapine at the time of screening."5.08Different side effect profiles of risperidone and clozapine in 20 outpatients with schizophrenia or schizoaffective disorder: a pilot study. ( Daniel, DG; Goldberg, TE; Kleinman, JE; Lubick, LJ; Pickar, D; Weinberger, DR; Williams, TS, 1996)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (18.75)18.2507
2000's5 (31.25)29.6817
2010's6 (37.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Shimizu, Y1
Taga, M1
Takahashi, Y1
Yamamoto, Y1
Masauji, T1
Herrera-Huerta, CA1
Hernández-Salas, LP1
Magallanes-Cano, EM1
Cawkwell, P1
Lawler, A1
Maneta, E1
Coffey, BJ1
Kane, JM1
Correll, CU1
Goff, DC1
Kirkpatrick, B1
Marder, SR1
Vester-Blokland, E1
Sun, W1
Carson, WH1
Pikalov, A1
Assunção-Talbott, S1
Fleischhacker, WW1
Gopal, S1
Lane, R1
Gassmann-Mayer, C1
Lim, P1
Hough, D1
Remmerie, B1
Eerdekens, M2
Salinas Botrán, A1
Urgelés Puértolas, D1
Peregrin Abad, E1
Baandrup, L1
Jennum, P1
Lublin, H1
Glenthoj, B1
Andrade, C1
Suresh Kumar, PN1
Khazaie, H1
Rezaie, L1
Darvishi, F1
Najafi, F1
Avis, K1
Lindenmayer, JP1
Eerdekens, E1
Berry, SA1
Eren, I1
Ozcankaya, R1
Altinyazar, V1
Addington, DE1
Pantelis, C1
Dineen, M1
Benattia, I1
Romano, SJ1
Yamashita, H1
Mori, K1
Nagao, M1
Okamoto, Y1
Morinobu, S1
Yamawaki, S1
Byerly, MJ1
Greer, RA1
Evans, DL1
Daniel, DG1
Goldberg, TE1
Weinberger, DR1
Kleinman, JE1
Pickar, D1
Lubick, LJ1
Williams, TS1
Doan, RJ1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Randomized, Double-blind, Placebo-controlled, 16 Week Study of Aripiprazole Used as Dual Therapy in the Treatment of Patients With Chronic Stable Schizophrenia or Schizoaffective Disorder Demonstrating an Inadequate Response to Quetiapine o[NCT00325689]Phase 4323 participants (Actual)Interventional2006-07-31Completed
A Randomized, Double-Blind, Parallel Group, Comparative Study of Flexibly Dosed Paliperidone Palmitate (25, 50, 75, or 100 mg eq.) Administered Every 4 Weeks and Flexibly Dosed RISPERDAL CONSTA (25, 37.5, or 50 mg) Administered Every 2 Weeks in Subjects W[NCT00210717]Phase 3748 participants (Actual)Interventional2005-02-28Completed
Open-Label Trial Exploring A Switching Regimen From Oral Neuroleptics, Other Than Risperidone, To Risperidone Depot Microspheres[NCT00034775]Phase 3141 participants (Actual)Interventional2001-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for risperidone and Sleep Initiation and Maintenance Disorders

ArticleYear
Treatment options for residual insomnia in schizophrenia.
    Acta psychiatrica Scandinavica, 2013, Volume: 127, Issue:1

    Topics: Antipsychotic Agents; Central Nervous System Depressants; Humans; Isoxazoles; Melatonin; Paliperidon

2013

Trials

7 trials available for risperidone and Sleep Initiation and Maintenance Disorders

ArticleYear
A multicenter, randomized, double-blind, placebo-controlled, 16-week study of adjunctive aripiprazole for schizophrenia or schizoaffective disorder inadequately treated with quetiapine or risperidone monotherapy.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:10

    Topics: Adult; Ambulatory Care; Antipsychotic Agents; Aripiprazole; Diagnostic and Statistical Manual of Men

2009
A randomized trial of paliperidone palmitate and risperidone long-acting injectable in schizophrenia.
    The international journal of neuropsychopharmacology, 2012, Volume: 15, Issue:1

    Topics: Administration, Oral; Adult; Antipsychotic Agents; Buttocks; Delayed-Action Preparations; Double-Bli

2012
Treatment of paradoxical insomnia with atypical antipsychotic drugs. A comparison of olanzapine and risperidone.
    Neurosciences (Riyadh, Saudi Arabia), 2013, Volume: 18, Issue:1

    Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Cross-Sectional Studies; Female; Follow-Up Studi

2013
Safety and efficacy of long-acting risperidone in schizophrenia: a 12-week, multicenter, open-label study in stable patients switched from typical and atypical oral antipsychotics.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:8

    Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Diarrhea; Drug Administration Schedule; Dr

2004
Efficacy and tolerability of ziprasidone versus risperidone in patients with acute exacerbation of schizophrenia or schizoaffective disorder: an 8-week, double-blind, multicenter trial.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:12

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Double-Blind Method; Female; Follow-Up Studies

2004
Influence of aging on the improvement of subjective sleep quality by atypical antipsychotic drugs in patients with schizophrenia: comparison of middle-aged and older adults.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005, Volume: 13, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepin

2005
Different side effect profiles of risperidone and clozapine in 20 outpatients with schizophrenia or schizoaffective disorder: a pilot study.
    The American journal of psychiatry, 1996, Volume: 153, Issue:3

    Topics: Akathisia, Drug-Induced; Ambulatory Care; Clozapine; Cognition Disorders; Cross-Over Studies; Humans

1996

Other Studies

8 other studies available for risperidone and Sleep Initiation and Maintenance Disorders

ArticleYear
Risk assessment of accidental falls in patients taking trazodone, quetiapine, or risperidone for insomnia: A single-center, case-control study.
    Neuropsychopharmacology reports, 2022, Volume: 42, Issue:4

    Topics: Accidental Falls; Case-Control Studies; Child; Humans; Quetiapine Fumarate; Risk Assessment; Risperi

2022
Cycloid psychosis and its longitudinal diagnosis: case report.
    Actas espanolas de psiquiatria, 2020, Volume: 48, Issue:1

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Female; Haloperidol; Humans; Hypnotics and Sedat

2020
Staying Up at Night: Overlapping Bipolar and Obsessive-Compulsive Disorder Symptoms in an Adolescent with Autism Spectrum Disorder.
    Journal of child and adolescent psychopharmacology, 2016, Volume: 26, Issue:1

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Autism Spectrum Disorder

2016
[Postpartum psychosis associated with cabergoline].
    Medicina clinica, 2013, Jan-05, Volume: 140, Issue:1

    Topics: Adult; Antipsychotic Agents; Cabergoline; Cesarean Section; Dopamine Agonists; Ergolines; Female; Ha

2013
Treating residual insomnia in schizophrenia: examining the options.
    Acta psychiatrica Scandinavica, 2013, Volume: 127, Issue:1

    Topics: Antipsychotic Agents; Central Nervous System Depressants; Humans; Isoxazoles; Melatonin; Paliperidon

2013
Risperidone-induced rabbit syndrome in mood disorder.
    European psychiatry : the journal of the Association of European Psychiatrists, 2004, Volume: 19, Issue:7

    Topics: Antipsychotic Agents; Depressive Disorder, Major; Diagnosis, Differential; Hallucinations; Humans; M

2004
Behavioral stimulation associated with risperidone initiation.
    The American journal of psychiatry, 1995, Volume: 152, Issue:7

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Anxiety; Benzodiazepines; Confusion; Female; Humans;

1995
Risperidone for insomnia in PDDs.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:10

    Topics: Antipsychotic Agents; Autistic Disorder; Child; Child, Preschool; Dose-Response Relationship, Drug;

1998