Page last updated: 2024-11-03

risperidone and Pregnancy

risperidone has been researched along with Pregnancy in 68 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"A search of the Benefit Risk Management Worldwide Safety database, using a selection of preferred terms from the Medical Dictionary of Regulatory Activities, was performed to identify all cases of pregnancy or fetal/neonatal outcomes reported in association with risperidone treatment from its first market launch (international birth date, 1 June 1993) to 31 December 2004."8.84Evaluating the postmarketing experience of risperidone use during pregnancy: pregnancy and neonatal outcomes. ( Coppola, D; Kwarta, RF; Russo, LJ; Schmider, J; Varughese, R, 2007)
"This study aimed to determine the effects of pregnancy and ontogeny on risperidone and paliperidone pharmacokinetics by assessing their serum concentrations in two subjects and constructing a customized physiologically-based pharmacokinetic (PBPK) model."8.31Physiologically-based pharmacokinetic model to investigate the effect of pregnancy on risperidone and paliperidone pharmacokinetics: Application to a pregnant woman and her neonate. ( Fujioka, K; Fujiwara, N; Horai, T; Iijima, K; Imafuku, H; Ito, T; Mahdy, WYB; Omura, T; Otsuka, I; Yamamoto, K; Yano, I, 2023)
"While numerous studies have confirmed the efficacy of risperidone long-acting injectable (RLAI) on many clinical outcomes in patients with schizophrenia, there is no data regarding its influence on employment status."7.83Remission and employment status in schizophrenia and other psychoses: One-year prospective study in Croatian patients treated with risperidone long acting injection. ( Emsley, R; Filipcic, IS; Grosic, V; Mihaljevic-Peles, A; Pedisic, I; Sagud, M, 2016)
"The aims of this study were to investigate bone mass, body composition and light microscopic pathology examinations of femur in an animal model of schizophrenia (pharmacologically induced by postnatally administered phencyclidine-PCP) and to further examine the effects of chronic treatment with risperidone on these parameters in rats."7.79Chronic risperidone exposure does not show any evidence of bone mass deterioration in animal model of schizophrenia. ( Doknic, M; Jasovic-Gasic, M; Maric, N; Pekic, S; Petronijevic, M; Petronijevic, N; Popovic, V; Radonjic, N; Sopta, J, 2013)
"Data on the use of long-acting injectable (LAI) risperidone, the first atypical depot antipsychotic, during pregnancy are limited."7.74Use of long-acting injectable risperidone before and throughout pregnancy in schizophrenia. ( Kim, JM; Kim, KM; Kim, SW; Shin, HY; Shin, IS; Yang, SJ; Yoon, JS, 2007)
"A follow-up of a case of pregnancy with risperidone microspheres is reported."7.73Follow-up of a pregnancy with risperidone microspheres. ( Dabbert, D; Heinze, M, 2006)
" The parturient developed exaggerated hypotension, refractory to conventional treatment with ephedrine and IV fluids, that eventually responded to large doses of phenylephrine."7.72Risperidone and exaggerated hypotension during a spinal anesthetic. ( Hepner, DL; Williams, JH, 2004)
"Schizophrenia is a disorder of a neurodevelopmental origin manifested symptomatically after puberty."5.37Risperidone administered during asymptomatic period of adolescence prevents the emergence of brain structural pathology and behavioral abnormalities in an animal model of schizophrenia. ( Arad, M; Piontkewitz, Y; Weiner, I, 2011)
"Valnoctamide could be an important valproate substitute for women of childbearing age with bipolar disorder who may become pregnant."5.14Valnoctamide as a valproate substitute with low teratogenic potential in mania: a double-blind, controlled, add-on clinical trial. ( Agam, G; Applebaum, J; Belmaker, RH; Bersudsky, Y; Gaiduk, Y; Mishory, A; Podberezsky, A; Sharony, L, 2010)
"A search of the Benefit Risk Management Worldwide Safety database, using a selection of preferred terms from the Medical Dictionary of Regulatory Activities, was performed to identify all cases of pregnancy or fetal/neonatal outcomes reported in association with risperidone treatment from its first market launch (international birth date, 1 June 1993) to 31 December 2004."4.84Evaluating the postmarketing experience of risperidone use during pregnancy: pregnancy and neonatal outcomes. ( Coppola, D; Kwarta, RF; Russo, LJ; Schmider, J; Varughese, R, 2007)
"This study aimed to determine the effects of pregnancy and ontogeny on risperidone and paliperidone pharmacokinetics by assessing their serum concentrations in two subjects and constructing a customized physiologically-based pharmacokinetic (PBPK) model."4.31Physiologically-based pharmacokinetic model to investigate the effect of pregnancy on risperidone and paliperidone pharmacokinetics: Application to a pregnant woman and her neonate. ( Fujioka, K; Fujiwara, N; Horai, T; Iijima, K; Imafuku, H; Ito, T; Mahdy, WYB; Omura, T; Otsuka, I; Yamamoto, K; Yano, I, 2023)
" Peak prolactin levels/any hyperprolactinemia/triple-upper-limit-of-normal-prolactin level were highest with risperidone (median = 56."4.31Antipsychotic-Related Prolactin Levels and Sexual Dysfunction in Mentally Ill Youth: A 3-Month Cohort Study. ( Carlson, HE; Correll, CU; Kazimi, MM; Koch, MT, 2023)
" The authors examined the risk of developing gestational diabetes associated with the continuation of treatment with aripiprazole, ziprasidone, quetiapine, risperidone, and olanzapine during pregnancy compared with discontinuation of these antipsychotic drugs."3.88Continuation of Atypical Antipsychotic Medication During Early Pregnancy and the Risk of Gestational Diabetes. ( Bateman, BT; Cohen, JM; Cohen, LS; Desai, RJ; Glynn, RJ; Hernandez-Diaz, S; Huybrechts, KF; Mogun, H; Park, Y; Patorno, E, 2018)
"Rodents exposed prenatally to valproic acid (VPA) exhibit autism spectrum disorder (ASD)-like behavioral abnormalities."3.85Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice. ( Ago, Y; Hara, Y; Hasebe, S; Hashimoto, H; Kawase, H; Matsuda, T; Nakazawa, T; Takuma, K; Tanabe, W; Taruta, A; Tsukada, S, 2017)
" Among AAPDs, risperidone (RIS) ranked third after olanzapine (OLZ) and quetiapine (QUE) used during pregnancy, as OLZ is associated to substantial weight gain in adults and offspring."3.83Effects of prenatal exposure to antipsychotic risperidone on developmental neurotoxicity, apoptotic neurodegeneration and neurobehavioral sequelae in rat offspring. ( Singh, KP; Singh, M; Singh, MK, 2016)
"While numerous studies have confirmed the efficacy of risperidone long-acting injectable (RLAI) on many clinical outcomes in patients with schizophrenia, there is no data regarding its influence on employment status."3.83Remission and employment status in schizophrenia and other psychoses: One-year prospective study in Croatian patients treated with risperidone long acting injection. ( Emsley, R; Filipcic, IS; Grosic, V; Mihaljevic-Peles, A; Pedisic, I; Sagud, M, 2016)
"Overall, our data suggest that maternal inflammation may contribute to an increased risk for schizophrenia through mechanisms involving metabolic function and myelin formation and that risperidone in adolescence may prevent or reverse such changes."3.81Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence. ( Cagney, G; Cannon, M; Cotter, DR; Dicker, P; English, J; Farrelly, L; Föcking, M; Piontkewitz, Y; Wynne, K, 2015)
" Given the scarcity of adequate data on its prenatal toxicity, a comparative teratogenicity study of valnoctamide and two of the most commonly used drugs to treat bipolar disorder, risperidone and olanzapine, was carried out in a mouse model system."3.81Comparative teratogenicity analysis of valnoctamide, risperidone, and olanzapine in mice. ( Bialer, M; Finnell, RH; Lin, LY; Ogle, K; Wlodarczyk, BJ, 2015)
"The aims of this study were to investigate bone mass, body composition and light microscopic pathology examinations of femur in an animal model of schizophrenia (pharmacologically induced by postnatally administered phencyclidine-PCP) and to further examine the effects of chronic treatment with risperidone on these parameters in rats."3.79Chronic risperidone exposure does not show any evidence of bone mass deterioration in animal model of schizophrenia. ( Doknic, M; Jasovic-Gasic, M; Maric, N; Pekic, S; Petronijevic, M; Petronijevic, N; Popovic, V; Radonjic, N; Sopta, J, 2013)
"Perinatal phencyclidine (PCP) administration to rats represents one of the actual animal models of schizophrenia."3.78Risperidone reverses phencyclidine induced decrease in glutathione levels and alterations of antioxidant defense in rat brain. ( Doknić, M; Jevtić, G; Petronijević, ND; Popović, V; Radonjić, NV; Stojković, T; Velimirović, M, 2012)
" The authors report a case of a woman with schizophrenia wherein risperidone was used successfully in two consecutive pregnancies."3.74Risperidone therapy in two successive pregnancies. ( Lohia, D; Mendhekar, D, 2008)
"Data on the use of long-acting injectable (LAI) risperidone, the first atypical depot antipsychotic, during pregnancy are limited."3.74Use of long-acting injectable risperidone before and throughout pregnancy in schizophrenia. ( Kim, JM; Kim, KM; Kim, SW; Shin, HY; Shin, IS; Yang, SJ; Yoon, JS, 2007)
"The authors conducted a prospective observational study of women treated with an atypical antipsychotic or haloperidol during pregnancy."3.74Atypical antipsychotic administration during late pregnancy: placental passage and obstetrical outcomes. ( Beach, AJ; Calamaras, MR; DeVane, CL; Donovan, J; Gibson, BB; Knight, BT; Nemeroff, CB; Newport, DJ; Owens, MJ; Stowe, ZN; Viguera, AC; Winn, S, 2007)
"A follow-up of a case of pregnancy with risperidone microspheres is reported."3.73Follow-up of a pregnancy with risperidone microspheres. ( Dabbert, D; Heinze, M, 2006)
" The parturient developed exaggerated hypotension, refractory to conventional treatment with ephedrine and IV fluids, that eventually responded to large doses of phenylephrine."3.72Risperidone and exaggerated hypotension during a spinal anesthetic. ( Hepner, DL; Williams, JH, 2004)
"Our case (36-year old) has suffered schizophrenia (DSM-IV) for 5 years and used these drugs (risperidone, quetiapine, mirtazapine, thioridazine, diazepam, hydroxyzine, clomipramine, fluvoxamine, alprazolam, carbamazepine, biperiden, haloperidol, ampicillin+sulbactam, enoxaparin, oxerutine) in her third pregnancy."3.72Use of polypharmacotherapy in pregnancy: a prospective outcome in a case. ( Kadioglu, M; Kalyoncu, NI; Kesim, M; Ulku, C; Yaris, E; Yaris, F, 2004)
"Mucopolysaccharidosis IIIA (MPS IIIA) is a lysosomal storage disorder characterized by progressive mental deterioration and severe behavioral problems."2.75Clinical overview of children with mucopolysaccharidosis type III A and effect of Risperidone treatment on children and their mothers psychological status. ( Coker, M; Demiral, N; Erermis, S; Kalkan Ucar, S; Ozbaran, B; Yuncu, Z, 2010)
"Schizophrenia is a severe neuropsychiatric disease associated with substantially higher mortality."1.62Interacting effects of the MAM model of schizophrenia and antipsychotic treatment: Untargeted proteomics approach in adipose tissue. ( Bienertova-Vasku, J; Horska, K; Hruska, P; Kucera, J; Kuruczova, D; Micale, V; Ruda-Kucerova, J, 2021)
" The current report presents adverse events in an infant exposed to a combination of risperidone and haloperidol through breast milk."1.51Adverse Events in a Breastfed Infant Exposed to Risperidone and Haloperidol. ( Uguz, F, 2019)
"Infant delirium is an under-recognized clinical entity in neonatal intensive care, and earlier identification and treatment could minimize morbidities associated with this condition."1.46A case of infant delirium in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB, 2017)
"Schizophrenia is associated with behavioral and brain structural abnormalities, of which the hippocampus appears to be one of the most consistent region affected."1.43Maturation- and sex-sensitive depression of hippocampal excitatory transmission in a rat schizophrenia model. ( Attali, B; Patrich, E; Peretz, A; Piontkewitz, Y; Weiner, I, 2016)
"Risperidone was discontinued and, owing to ongoing psychosis, olanzapine was initiated."1.38Antipsychotics leading to neuroleptic malignant syndrome in pregnancy. ( Aghajanian, P; Dossett, E; Ghaffari, N; Lee, RH, 2012)
"Schizophrenia is a disorder of a neurodevelopmental origin manifested symptomatically after puberty."1.37Risperidone administered during asymptomatic period of adolescence prevents the emergence of brain structural pathology and behavioral abnormalities in an animal model of schizophrenia. ( Arad, M; Piontkewitz, Y; Weiner, I, 2011)
"Transient prenatal vitamin D deficiency is considered a neurodevelopmental animal model in schizophrenia research."1.35Transient prenatal vitamin D deficiency is associated with changes of synaptic plasticity in the dentate gyrus in adult rats. ( Becker, A; Grecksch, G; Höllt, V; Rüthrich, H, 2009)
"Antipsychotic treatment during pregnancy is indicated when risk of drug exposure to the fetus is outweighed by the untreated psychosis in the mother."1.35Distinct neurobehavioral consequences of prenatal exposure to sulpiride (SUL) and risperidone (RIS) in rats. ( Hao, Y; Liu, H; Liu, Z; Lu, XH; Ouyang, X; Xu, L; Zuo, J, 2008)
"Transient prenatal Vitamin D deficiency is considered a developmental model in schizophrenia research."1.33Pharmacological treatment to augment hole board habituation in prenatal Vitamin D-deficient rats. ( Becker, A; Grecksch, G, 2006)
"Risperidone was the antipsychotic employed and elevation of prolactin concentrations were noted each time."1.32Delusions of pregnancy associated with increased prolactin concentrations produced by antipsychotic treatment. ( Ali, JA; Ali, LJ; Desai, KD, 2003)
"Family history of psychiatric illness and the presence of obstetric complications were estimated by a semistructured questionnaire."1.31Does risperidone act better in schizophrenic patients who have a family or obstetric history? ( Borkowska, A; Rybakowski, JK, 2002)

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.47)18.2507
2000's22 (32.35)29.6817
2010's36 (52.94)24.3611
2020's9 (13.24)2.80

Authors

AuthorsStudies
Elnahas, EM2
Abuelezz, SA1
Mohamad, MI1
Nabil, MM1
Abdelraouf, SM1
Bahaa, N1
Hassan, GAM1
Aboul-Fotouh, S2
Lian, J1
Han, M1
Su, Y1
Hodgson, J1
Deng, C1
Mishra, A1
Singla, R1
Kumar, R1
Sharma, A1
Joshi, R1
Sarma, P1
Kaur, G1
Prajapat, M1
Bhatia, A1
Medhi, B1
Mahdy, WYB1
Yamamoto, K1
Ito, T1
Fujiwara, N1
Fujioka, K1
Horai, T1
Otsuka, I1
Imafuku, H1
Omura, T1
Iijima, K1
Yano, I1
Koch, MT1
Carlson, HE1
Kazimi, MM1
Correll, CU1
Habib, MZ1
Aboul-Ela, YM1
Ebeid, MA1
Tarek, M1
Sadek, DR1
Negm, EA1
Abdelhakam, DA1
Amini, A1
Namvarpour, Z1
Namvarpour, M1
Raoofi, A1
Kucera, J1
Horska, K1
Hruska, P1
Kuruczova, D1
Micale, V1
Ruda-Kucerova, J1
Bienertova-Vasku, J1
Rush Ortegon, E1
Ferguson, J1
Coffey, BJ1
Kuppili, PP1
Gupta, R1
Pattanayak, RD1
Khandelwal, SK1
Farrelly, L2
Rosato-Siri, MV1
Föcking, M2
Codagnone, M1
Reines, A1
Dicker, P2
Wynne, K2
Farrell, M1
Cannon, M2
Cagney, G2
Pasquini, JM1
Cotter, DR2
Hara, Y1
Ago, Y1
Taruta, A1
Hasebe, S1
Kawase, H1
Tanabe, W1
Tsukada, S1
Nakazawa, T1
Hashimoto, H1
Matsuda, T1
Takuma, K1
Park, Y1
Hernandez-Diaz, S2
Bateman, BT2
Cohen, JM2
Desai, RJ2
Patorno, E2
Glynn, RJ1
Cohen, LS1
Mogun, H2
Huybrechts, KF2
Newcomer, JW1
Nicol, GE1
Wang, H1
Li, JT1
Zhang, Y1
Liu, R1
Wang, XD1
Si, TM1
Su, YA1
Lertxundi, U1
Erezuma, I1
Hernandez, R1
Medrano, J1
Garcia, M1
Aguirre, C1
Takahashi, K1
Nakagawasai, O1
Sakuma, W1
Nemoto, W1
Odaira, T1
Lin, JR1
Onogi, H1
Srivastava, LK1
Tan-No, K1
Uguz, F1
Petronijevic, N1
Sopta, J1
Doknic, M2
Radonjic, N1
Petronijevic, M1
Pekic, S1
Maric, N1
Jasovic-Gasic, M1
Popovic, V2
Chatterjee, B1
Sharan, P1
Ennis, ZN1
Damkier, P1
Piontkewitz, Y4
English, J1
Kulkarni, J3
Storch, A1
Baraniuk, A1
Gilbert, H1
Gavrilidis, E1
Worsley, R1
Wlodarczyk, BJ1
Ogle, K1
Lin, LY1
Bialer, M1
Finnell, RH1
Patrich, E1
Peretz, A1
Weiner, I3
Attali, B1
Colombel, M1
Rebillard, C1
Nathou, C1
Dollfus, S1
Singh, KP3
Singh, MK3
Singh, M1
Gautam, S1
Dejene, SZ1
Panchaud, A1
Cohen, L1
Mihaljevic-Peles, A1
Sagud, M1
Filipcic, IS1
Grosic, V1
Pedisic, I1
Emsley, R1
Edwards, LE1
Hutchison, LB1
Hornik, CD1
Smith, PB1
Cotten, CM1
Bidegain, M1
Llorca, PM1
Bouhours, P1
Moreau-Mallet, V1
Mendhekar, D1
Lohia, D1
Kalkan Ucar, S1
Ozbaran, B1
Demiral, N1
Yuncu, Z1
Erermis, S1
Coker, M1
Pasini, A1
D'Agati, E1
Casarelli, L1
Curatolo, P1
Grecksch, G2
Rüthrich, H1
Höllt, V1
Becker, A2
Arad, M1
McCauley-Elsom, K2
Gurvich, C1
Elsom, SJ1
Bersudsky, Y1
Applebaum, J1
Gaiduk, Y1
Sharony, L1
Mishory, A1
Podberezsky, A1
Agam, G1
Belmaker, RH1
Weggelaar, NM1
Keijer, WJ1
Janssen, PK1
Richtand, NM3
Ahlbrand, R3
Horn, P1
Stanford, K1
Bronson, SL2
McNamara, RK2
Roenker, NL1
Gudelsky, G1
Kern, JR1
Waterman, H1
Bernstein, HG1
Dobrowolny, H1
Bogerts, B1
Keilhoff, G1
Ghaffari, N1
Dossett, E1
Lee, RH1
Aghajanian, P1
Stojković, T1
Radonjić, NV1
Velimirović, M1
Jevtić, G1
Petronijević, ND1
Salinas Botrán, A1
Urgelés Puértolas, D1
Peregrin Abad, E1
Wilson, CA1
Terry, AV1
Rosengarten, H1
Quartermain, D1
Borkowska, A1
Rybakowski, JK1
Ali, JA1
Desai, KD1
Ali, LJ1
Williams, JH1
Hepner, DL1
Yaris, F1
Yaris, E1
Kadioglu, M1
Ulku, C1
Kesim, M1
Kalyoncu, NI1
Rueter, LE1
Ballard, ME1
Gallagher, KB1
Basso, AM1
Curzon, P1
Kohlhaas, KL1
Curtis, V1
Kato, R1
Sato, J1
Suzuki, H1
Taylor, B1
Welge, JA1
Ostrander, MM1
Burr, J1
Hayes, S1
Coolen, LM1
Pritchard, LM1
Logue, A1
Herman, JP1
Kim, SW1
Kim, KM1
Kim, JM1
Shin, IS1
Shin, HY1
Yang, SJ1
Yoon, JS1
Dabbert, D1
Heinze, M1
Coppola, D1
Russo, LJ1
Kwarta, RF1
Varughese, R1
Schmider, J1
Newport, DJ1
Calamaras, MR1
DeVane, CL1
Donovan, J1
Beach, AJ1
Winn, S1
Knight, BT1
Gibson, BB1
Viguera, AC1
Owens, MJ1
Nemeroff, CB1
Stowe, ZN1
Zuo, J1
Liu, Z1
Ouyang, X1
Liu, H1
Hao, Y1
Xu, L1
Lu, XH1
Hill, RC1
McIvor, RJ1
Wojnar-Horton, RE1
Hackett, LP1
Ilett, KF1
Ratnayake, T1
Libretto, SE1
Gil-ad, I1
Shtaif, B1
Shiloh, R1
Weizman, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Medication Safety and Contraceptive Counseling for Reproductive Aged Women With Psychiatric Conditions[NCT02292056]50 participants (Anticipated)Interventional2013-09-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for risperidone and Pregnancy

ArticleYear
Pregnancy exposure to olanzapine, quetiapine, risperidone, aripiprazole and risk of congenital malformations. A systematic review.
    Basic & clinical pharmacology & toxicology, 2015, Volume: 116, Issue:4

    Topics: Abnormalities, Drug-Induced; Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Female; Hum

2015
Antipsychotic use in pregnancy.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:9

    Topics: Abnormalities, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Female; Huma

2015
Antipsychotics in pregnancy.
    Journal of psychiatric and mental health nursing, 2010, Volume: 17, Issue:2

    Topics: Abnormalities, Drug-Induced; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Diabete

2010
Women are not the same as men: specific clinical issues for female patients with bipolar disorder.
    Bipolar disorders, 2005, Volume: 7 Suppl 1

    Topics: Anticonvulsants; Antidepressive Agents; Benzodiazepines; Bipolar Disorder; Counseling; Dibenzothiaze

2005
Evaluating the postmarketing experience of risperidone use during pregnancy: pregnancy and neonatal outcomes.
    Drug safety, 2007, Volume: 30, Issue:3

    Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Adult; Antipsychotic Agents;

2007

Trials

2 trials available for risperidone and Pregnancy

ArticleYear
Clinical overview of children with mucopolysaccharidosis type III A and effect of Risperidone treatment on children and their mothers psychological status.
    Brain & development, 2010, Volume: 32, Issue:2

    Topics: Adolescent; Antipsychotic Agents; Child; Child Behavior Disorders; Child, Preschool; Cross-Over Stud

2010
Valnoctamide as a valproate substitute with low teratogenic potential in mania: a double-blind, controlled, add-on clinical trial.
    Bipolar disorders, 2010, Volume: 12, Issue:4

    Topics: Adult; Amides; Animals; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Double-Blind Method

2010

Other Studies

61 other studies available for risperidone and Pregnancy

ArticleYear
Novel role of peroxisome proliferator activated receptor-α in valproic acid rat model of autism: Mechanistic study of risperidone and metformin monotherapy versus combination.
    Progress in neuro-psychopharmacology & biological psychiatry, 2022, 06-08, Volume: 116

    Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Behavior, Animal; Disease Models, Animal; Fema

2022
The long-lasting effects of early antipsychotic exposure during juvenile period on adult behaviours - A study in a poly I:C rat model.
    Pharmacology, biochemistry, and behavior, 2022, Volume: 219

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Female; Humans; Male; Olanzapine; Poly I-C; Pregnancy;

2022
Granulocyte Colony-Stimulating Factor Improved Core Symptoms of Autism Spectrum Disorder via Modulating Glutamatergic Receptors in the Prefrontal Cortex and Hippocampus of Rat Brains.
    ACS chemical neuroscience, 2022, 10-19, Volume: 13, Issue:20

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autism Spectrum Disorder; Brain;

2022
Physiologically-based pharmacokinetic model to investigate the effect of pregnancy on risperidone and paliperidone pharmacokinetics: Application to a pregnant woman and her neonate.
    Clinical and translational science, 2023, Volume: 16, Issue:4

    Topics: Adult; Child; Cytochrome P-450 CYP2D6; Female; Humans; Infant, Newborn; Models, Biological; Paliperi

2023
Antipsychotic-Related Prolactin Levels and Sexual Dysfunction in Mentally Ill Youth: A 3-Month Cohort Study.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2023, Volume: 62, Issue:9

    Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Cohort Studies; Erectile Dysfunctio

2023
Risperidone impedes glutamate excitotoxicity in a valproic acid rat model of autism: Role of ADAR2 in AMPA GluA2 RNA editing.
    European journal of pharmacology, 2023, Sep-15, Volume: 955

    Topics: Adenosine Deaminase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autism Spect

2023
Risperidone accelerates bone loss in rats with autistic-like deficits induced by maternal lipopolysaccharides exposure.
    Life sciences, 2020, Oct-01, Volume: 258

    Topics: Animals; Animals, Newborn; Autistic Disorder; Behavior, Animal; Biomechanical Phenomena; Bone Resorp

2020
Interacting effects of the MAM model of schizophrenia and antipsychotic treatment: Untargeted proteomics approach in adipose tissue.
    Progress in neuro-psychopharmacology & biological psychiatry, 2021, 06-08, Volume: 108

    Topics: Adipose Tissue; Animals; Antipsychotic Agents; Disease Models, Animal; Female; Haloperidol; Intra-Ab

2021
A Prepubertal Girl with Delusions of Pregnancy.
    Journal of child and adolescent psychopharmacology, 2021, Volume: 31, Issue:5

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Delusions; Female; Humans; Hyperprolactinemia;

2021
Delusional denial of pregnancy: Unique presentation of Cotard's syndrome in a patient with schizophrenia.
    Asian journal of psychiatry, 2017, Volume: 30

    Topics: Adult; Antipsychotic Agents; Delusions; Denial, Psychological; Female; Humans; Pregnancy; Pregnancy

2017
The Effects of Prenatal Iron Deficiency and Risperidone Treatment on the Rat Frontal Cortex:  A Proteomic Analysis.
    Proteomics, 2017, Volume: 17, Issue:17-18

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Female; Frontal Lobe; Iron;

2017
Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice.
    Psychopharmacology, 2017, Volume: 234, Issue:21

    Topics: Animals; Aripiprazole; Autism Spectrum Disorder; Dendritic Spines; Disease Models, Animal; Dopamine;

2017
Continuation of Atypical Antipsychotic Medication During Early Pregnancy and the Risk of Gestational Diabetes.
    The American journal of psychiatry, 2018, 06-01, Volume: 175, Issue:6

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Diabetes, Gestational; Female; Humans; Olanzapine; Pipera

2018
Gestational Diabetes Risk During Treatment With Antipsychotic Medications.
    The American journal of psychiatry, 2018, 06-01, Volume: 175, Issue:6

    Topics: Antipsychotic Agents; Diabetes, Gestational; Female; Humans; Pregnancy; Risk; Risperidone

2018
Prenatal Exposure to Antipsychotics Disrupts the Plasticity of Dentate Neurons and Memory in Adult Male Mice.
    The international journal of neuropsychopharmacology, 2019, 01-01, Volume: 22, Issue:1

    Topics: Animals; Antipsychotic Agents; Dentate Gyrus; Female; Haloperidol; Male; Memory; Mice, Inbred C57BL;

2019
Antipsychotics and pituitary tumors: an analysis of the European pharmacovigilance database (EudraVigilance).
    International clinical psychopharmacology, 2019, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Child; Databases, Factual; Female; Halop

2019
Prenatal treatment with methylazoxymethanol acetate as a neurodevelopmental disruption model of schizophrenia in mice.
    Neuropharmacology, 2019, 05-15, Volume: 150

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Clozapine; Disease Models, Animal; Fe

2019
Adverse Events in a Breastfed Infant Exposed to Risperidone and Haloperidol.
    Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 2019, Volume: 14, Issue:9

    Topics: Antipsychotic Agents; Dietary Exposure; Drug Therapy, Combination; Female; Haloperidol; Humans; Infa

2019
Chronic risperidone exposure does not show any evidence of bone mass deterioration in animal model of schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Oct-01, Volume: 46

    Topics: Animals; Animals, Newborn; Antipsychotic Agents; Bone Density; Bone Resorption; Female; Male; Pregna

2013
Tardive dyskinesia in a pregnant woman with low dose, short-duration risperidone: possible role of estrogen-induced dopaminergic hypersensitivity.
    The Journal of neuropsychiatry and clinical neurosciences, 2014,Winter, Volume: 26, Issue:1

    Topics: Adult; Bipolar Disorder; Dopamine Antagonists; Estrogens; Female; Humans; Movement Disorders; Pregna

2014
Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence.
    Developmental neuroscience, 2015, Volume: 37, Issue:1

    Topics: Aging; Animals; Antipsychotic Agents; Disease Models, Animal; Female; Male; Myelin Sheath; Prefronta

2015
Comparative teratogenicity analysis of valnoctamide, risperidone, and olanzapine in mice.
    Bipolar disorders, 2015, Volume: 17, Issue:6

    Topics: Amides; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Disea

2015
Maturation- and sex-sensitive depression of hippocampal excitatory transmission in a rat schizophrenia model.
    Brain, behavior, and immunity, 2016, Volume: 51

    Topics: Animals; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; Hippocampus; Male; Orga

2016
[Can men be included in the population subjected to puerperal psychosis? A case report].
    L'Encephale, 2016, Volume: 42, Issue:4

    Topics: Adolescent; Affective Disorders, Psychotic; Antipsychotic Agents; Delusions; Denial, Psychological;

2016
Effects of prenatal exposure to antipsychotic risperidone on developmental neurotoxicity, apoptotic neurodegeneration and neurobehavioral sequelae in rat offspring.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2016, Volume: 52

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Annexin A5; Antipsychotic Agents; Apop

2016
Effect of in utero exposure to the atypical anti-psychotic risperidone on histopathological features of the rat placenta.
    International journal of experimental pathology, 2016, Volume: 97, Issue:2

    Topics: Animals; Antipsychotic Agents; Female; Fetal Development; Maternal Exposure; Maternal-Fetal Exchange

2016
Antipsychotic Use in Pregnancy and the Risk for Congenital Malformations.
    JAMA psychiatry, 2016, 09-01, Volume: 73, Issue:9

    Topics: Abnormalities, Drug-Induced; Adult; Antipsychotic Agents; Cohort Studies; Female; Heart Defects, Con

2016
Remission and employment status in schizophrenia and other psychoses: One-year prospective study in Croatian patients treated with risperidone long acting injection.
    Psychiatria Danubina, 2016, Volume: 28, Issue:3

    Topics: Adult; Croatia; Delayed-Action Preparations; Employment; Female; Humans; Injections, Intramuscular;

2016
In utero exposure to atypical antipsychotic drug, risperidone: Effects on fetal neurotoxicity in hippocampal region and cognitive impairment in rat offspring.
    Progress in neuro-psychopharmacology & biological psychiatry, 2017, 04-03, Volume: 75

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antipsychotic Agents; Apoptosis; Avoidance Learning

2017
A case of infant delirium in the neonatal intensive care unit.
    Journal of neonatal-perinatal medicine, 2017, Volume: 10, Issue:1

    Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acid

2017
Improved symptom control, functioning and satisfaction in French patients treated with long-acting injectable risperidone.
    L'Encephale, 2008, Volume: 34, Issue:2

    Topics: Adult; Antipsychotic Agents; Catchment Area, Health; Delayed-Action Preparations; Depression, Postpa

2008
Risperidone therapy in two successive pregnancies.
    The Journal of neuropsychiatry and clinical neurosciences, 2008,Fall, Volume: 20, Issue:4

    Topics: Antipsychotic Agents; Female; Humans; Infant, Newborn; Male; Pregnancy; Pregnancy Complications; Pre

2008
Dose-dependent effect of risperidone treatment in a case of 22q13.3 deletion syndrome.
    Brain & development, 2010, Volume: 32, Issue:5

    Topics: Abnormalities, Multiple; Adolescent; Aggression; Animals; Antipsychotic Agents; Chromosome Deletion;

2010
Transient prenatal vitamin D deficiency is associated with changes of synaptic plasticity in the dentate gyrus in adult rats.
    Psychoneuroendocrinology, 2009, Volume: 34 Suppl 1

    Topics: Animals; Dentate Gyrus; Female; Haloperidol; Long-Term Potentiation; Male; Neuronal Plasticity; Preg

2009
Risperidone administered during asymptomatic period of adolescence prevents the emergence of brain structural pathology and behavioral abnormalities in an animal model of schizophrenia.
    Schizophrenia bulletin, 2011, Volume: 37, Issue:6

    Topics: Age Factors; Animals; Antipsychotic Agents; Behavior, Animal; Brain; Disease Models, Animal; Female;

2011
A case report of risperidone distribution and excretion into human milk: how to give good advice if you have not enough data available.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:1

    Topics: Adult; Female; Humans; Infant; Milk, Human; Patient Education as Topic; Pregnancy; Pregnancy Complic

2011
Effects of risperidone and paliperidone pre-treatment on locomotor response following prenatal immune activation.
    Journal of psychiatric research, 2011, Volume: 45, Issue:9

    Topics: Amphetamine; Animals; Animals, Newborn; Antipsychotic Agents; Central Nervous System Stimulants; Dis

2011
Effect of paliperidone and risperidone on extracellular glutamate in the prefrontal cortex of rats exposed to prenatal immune activation or MK-801.
    Neuroscience letters, 2011, Aug-18, Volume: 500, Issue:3

    Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; Extracellular Space; Fem

2011
Effects of risperidone treatment in adolescence on hippocampal neurogenesis, parvalbumin expression, and vascularization following prenatal immune activation in rats.
    Brain, behavior, and immunity, 2012, Volume: 26, Issue:2

    Topics: Animals; Bromodeoxyuridine; Female; Hippocampus; Male; Neurogenesis; Parvalbumins; Poly I-C; Pregnan

2012
Antipsychotics leading to neuroleptic malignant syndrome in pregnancy.
    Obstetrics and gynecology, 2012, Volume: 119, Issue:2 Pt 2

    Topics: Adult; Antipsychotic Agents; Female; Haloperidol; Humans; Neuroleptic Malignant Syndrome; Pregnancy;

2012
Risperidone reverses phencyclidine induced decrease in glutathione levels and alterations of antioxidant defense in rat brain.
    Progress in neuro-psychopharmacology & biological psychiatry, 2012, Oct-01, Volume: 39, Issue:1

    Topics: Animals; Antioxidants; Antipsychotic Agents; Brain; Disease Models, Animal; Female; Glutamate-Cystei

2012
[Postpartum psychosis associated with cabergoline].
    Medicina clinica, 2013, Jan-05, Volume: 140, Issue:1

    Topics: Adult; Antipsychotic Agents; Cabergoline; Cesarean Section; Dopamine Agonists; Ergolines; Female; Ha

2013
Variable maternal stress in rats alters locomotor activity, social behavior, and recognition memory in the adult offspring.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 104

    Topics: Adrenergic Uptake Inhibitors; Amphetamine; Animals; Antipsychotic Agents; Atomoxetine Hydrochloride;

2013
Effect of prenatal administration of haloperidol, risperidone, quetiapine and olanzapine on spatial learning and retention in adult rats.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 72, Issue:3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Dibenzothiazepines; Drinking; Female; Haloper

2002
Does risperidone act better in schizophrenic patients who have a family or obstetric history?
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:7-8

    Topics: Adolescent; Adult; Age of Onset; Antipsychotic Agents; Cognition Disorders; Female; Humans; Male; Me

2002
Delusions of pregnancy associated with increased prolactin concentrations produced by antipsychotic treatment.
    The international journal of neuropsychopharmacology, 2003, Volume: 6, Issue:2

    Topics: Adult; Antipsychotic Agents; Benztropine; Delusions; Dibenzothiazepines; Female; Humans; Middle Aged

2003
Risperidone and exaggerated hypotension during a spinal anesthetic.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Anesthesia, Spinal; Antimanic Agents

2004
Use of polypharmacotherapy in pregnancy: a prospective outcome in a case.
    Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:3

    Topics: Adult; Antipsychotic Agents; Apgar Score; Dibenzothiazepines; Drug Therapy, Combination; Female; Hum

2004
Chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia.
    Psychopharmacology, 2004, Volume: 176, Issue:3-4

    Topics: Acoustic Stimulation; Animals; Animals, Newborn; Antipsychotic Agents; Behavior, Animal; Clozapine;

2004
[Anesthesia for cesarean section in a parturient taking risperidone and haloperidol].
    Masui. The Japanese journal of anesthesiology, 2005, Volume: 54, Issue:3

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Antipsychotic Agents; Cesarean Section; Female;

2005
Risperidone pretreatment prevents elevated locomotor activity following neonatal hippocampal lesions.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:1

    Topics: Amphetamine; Animals; Animals, Newborn; Antipsychotic Agents; Circadian Rhythm; Dentate Gyrus; Dopam

2006
Pharmacological treatment to augment hole board habituation in prenatal Vitamin D-deficient rats.
    Behavioural brain research, 2006, Jan-06, Volume: 166, Issue:1

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Exploratory Behavior; Female; Glycine; Habituation,

2006
Use of long-acting injectable risperidone before and throughout pregnancy in schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Mar-30, Volume: 31, Issue:2

    Topics: Adult; Antipsychotic Agents; Drug Administration Schedule; Female; Humans; Injections; Pregnancy; Ri

2007
Follow-up of a pregnancy with risperidone microspheres.
    Pharmacopsychiatry, 2006, Volume: 39, Issue:6

    Topics: Adult; Antipsychotic Agents; Birth Weight; Female; Humans; Infant; Infant, Newborn; Microspheres; Pr

2006
Managing psychosis in pregnancy.
    The Australian and New Zealand journal of psychiatry, 2007, Volume: 41, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Case Management; Child Custody; Cooperative Behavior;

2007
Atypical antipsychotic administration during late pregnancy: placental passage and obstetrical outcomes.
    The American journal of psychiatry, 2007, Volume: 164, Issue:8

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Female; Fetal Blood; Haloperidol;

2007
Distinct neurobehavioral consequences of prenatal exposure to sulpiride (SUL) and risperidone (RIS) in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Feb-15, Volume: 32, Issue:2

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Body Weight; Brain; Conditioning, Psychological; Di

2008
FDA approved new drug bulletin: risperidone (risperdal).
    RN, 1994, Volume: 57, Issue:6

    Topics: Adult; Antipsychotic Agents; Child; Drug Interactions; Female; Humans; Isoxazoles; Patient Education

1994
Risperidone distribution and excretion into human milk: case report and estimated infant exposure during breast-feeding.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:2

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Breast Feeding; Female; Humans; Infant, Newborn; Isox

2000
No complications with risperidone treatment before and throughout pregnancy and during the nursing period.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:1

    Topics: Adult; Antipsychotic Agents; Female; Humans; Pregnancy; Pregnancy Complications; Pregnancy Outcome;

2002
Evaluation of the neurotoxic activity of typical and atypical neuroleptics: relevance to iatrogenic extrapyramidal symptoms.
    Cellular and molecular neurobiology, 2001, Volume: 21, Issue:6

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Brain; Cell Cycle; Cell Survival; Clozapine;

2001