risperidone has been researched along with Pituitary Neoplasms in 10 studies
Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.
Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Risperidone had the highest adjusted reporting ratios for hyperprolactinemia (EBGM 34." | 3.73 | Atypical antipsychotics and pituitary tumors: a pharmacovigilance study. ( Doraiswamy, PM; Levine, JG; Szarfman, A; Tonning, JM, 2006) |
| "Risperidone induced galactorrhea and hyperprolactinemia have been reported but its role in the growth of prolactinoma is not yet conclusive, due to extreme rarity of such cases." | 3.72 | Effect of risperidone on prolactinoma--a case report. ( Jiloha, RC; Mendhekar, DN; Srivastava, PK, 2004) |
| "The hazard ratio of confirmed pituitary tumors with mass effect was 1." | 1.38 | Follow-up study of a pharmacovigilance signal: no evidence of increased risk with risperidone of pituitary tumor with mass effect. ( Jiang, R; McAfee, AT; McCarren, M; Qiu, H; Wang, Y; Ziyadeh, N, 2012) |
| "Methadone (Mtd) is a widely used opioid drug associated with the side effect of hyperprolactinemia." | 1.37 | Inhibitory action of methadone and its metabolites on erg-mediated K+ current in GH₃ pituitary tumor cells. ( Chen, BS; Chen, CT; Hsu, TI; Huang, MH; Kang, YF; Shen, AY; Wang, TS; Wu, HM; Wu, SN, 2011) |
| " Preclinical evidence shows that chronic administration of antipsychotics can cause pituitary adenomas in female mice." | 1.34 | Atypical antipsychotics and pituitary neoplasms in the WHO database. ( Doraiswamy, PM; Edwards, R; Mueller-Oerlinghausen, B; Schott, G; Star, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ranjan, R | 1 |
| Nath, S | 1 |
| Mohapatra, D | 1 |
| Mishra, BR | 1 |
| Lertxundi, U | 1 |
| Erezuma, I | 1 |
| Hernandez, R | 1 |
| Medrano, J | 1 |
| Garcia, M | 1 |
| Aguirre, C | 1 |
| Sainani, A | 1 |
| Cabral, S | 1 |
| Huang, MH | 1 |
| Shen, AY | 1 |
| Wang, TS | 1 |
| Wu, HM | 1 |
| Kang, YF | 1 |
| Chen, CT | 1 |
| Hsu, TI | 1 |
| Chen, BS | 1 |
| Wu, SN | 1 |
| Ng, KW | 1 |
| Lee, J | 1 |
| Swapna, V | 1 |
| McCarren, M | 1 |
| Qiu, H | 1 |
| Ziyadeh, N | 1 |
| Jiang, R | 1 |
| Wang, Y | 1 |
| McAfee, AT | 1 |
| Molitch, ME | 1 |
| Mendhekar, DN | 1 |
| Jiloha, RC | 1 |
| Srivastava, PK | 1 |
| Szarfman, A | 1 |
| Tonning, JM | 1 |
| Levine, JG | 1 |
| Doraiswamy, PM | 2 |
| Schott, G | 1 |
| Star, K | 1 |
| Edwards, R | 1 |
| Mueller-Oerlinghausen, B | 1 |
10 other studies available for risperidone and Pituitary Neoplasms
| Article | Year |
|---|---|
"I am a sinner": Rathke's cleft cyst masquerading as delusion of guilt.
Topics: Antipsychotic Agents; Central Nervous System Cysts; Delusions; Female; Guilt; Humans; Magnetic Reson | 2018 |
Antipsychotics and pituitary tumors: an analysis of the European pharmacovigilance database (EudraVigilance).
Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Child; Databases, Factual; Female; Halop | 2019 |
Risperidone and pituitary adenomas.
Topics: Adult; Antipsychotic Agents; Female; Humans; Pituitary Neoplasms; Risperidone; Schizophrenia | 2009 |
Inhibitory action of methadone and its metabolites on erg-mediated K+ current in GH₃ pituitary tumor cells.
Topics: Animals; Cell Line, Tumor; Ether-A-Go-Go Potassium Channels; Methadone; Naloxone; Narcotics; Neurons | 2011 |
Management of a patient with schizophrenia and underlying pituitary macroadenoma.
Topics: Adenoma; Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bromocriptine; Dopamine Antagon | 2010 |
Follow-up study of a pharmacovigilance signal: no evidence of increased risk with risperidone of pituitary tumor with mass effect.
Topics: Adenoma; Adult; Aged; Case-Control Studies; Cohort Studies; Female; Follow-Up Studies; Humans; Longi | 2012 |
Atypical antipsychotics and pituitary tumors.
Topics: Adenoma; Female; Humans; Male; Pharmacovigilance; Pituitary Neoplasms; Risperidone | 2012 |
Effect of risperidone on prolactinoma--a case report.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Female; | 2004 |
Atypical antipsychotics and pituitary tumors: a pharmacovigilance study.
Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Amenorrhea; Antipsychotic Agents; Aripiprazole; | 2006 |
Atypical antipsychotics and pituitary neoplasms in the WHO database.
Topics: Adenoma; Adult; Adverse Drug Reaction Reporting Systems; Amisulpride; Antipsychotic Agents; Causalit | 2007 |