Page last updated: 2024-11-03

risperidone and Movement Disorders

risperidone has been researched along with Movement Disorders in 33 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
"This study aims to determine the effectiveness of paliperidone extended release (ER) on cognitive function in patients with schizophrenia in comparison with risperidone."9.16Paliperidone ER versus risperidone for neurocognitive function in patients with schizophrenia: a randomized, open-label, controlled trial. ( Bae, KY; Chung, YC; Kim, JM; Kim, SW; Kim, SY; Lee, JH; Lee, YH; Shin, IS; Yoon, JS, 2012)
"This case report documents the response of a young, first-episode, neuroleptic naive male with severe catatonic schizophrenia to the novel antipsychotic, risperidone."7.70Acute and longer-term effects of risperidone in a case of first-episode catatonic schizophrenia. ( Caudle, C; Kopala, LC, 1998)
" The results from the literature underline the necessity of caution and patient monitoring when risperidone dosing is modified during methylphenidate therapy."6.72Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance. ( Burden, AM; Stämpfli, D; Weiler, S, 2021)
"This study aims to determine the effectiveness of paliperidone extended release (ER) on cognitive function in patients with schizophrenia in comparison with risperidone."5.16Paliperidone ER versus risperidone for neurocognitive function in patients with schizophrenia: a randomized, open-label, controlled trial. ( Bae, KY; Chung, YC; Kim, JM; Kim, SW; Kim, SY; Lee, JH; Lee, YH; Shin, IS; Yoon, JS, 2012)
"Long-acting injectable risperidone was assessed in schizophrenia patients who were symptomatically stable on conventional depot antipsychotics and who were then switched to long-acting risperidone."5.11Long-acting injectable risperidone: safety and efficacy in stable patients switched from conventional depot antipsychotics. ( Eerdekens, E; Eerdekens, M; Jacko, M; Turner, M, 2004)
"The effects of risperidone and olanzapine on cognitive functioning in patients with schizophrenia were compared in a randomized, double-blind trial."5.10Changes in cognitive functioning with risperidone and olanzapine treatment: a large-scale, double-blind, randomized study. ( Green, MF; Harvey, PD; McGurk, SR; Meltzer, HY, 2003)
" Risperidone is associated with relatively few motor side effects compared with the traditional antipsychotics, and weight gain is less likely with risperidone than with either clozapine or olanzapine."4.80Risperidone side effects. ( Conley, RR, 2000)
"We describe the first child with guanidinoacetate methyltransferase (GAMT) deficiency who developed neuroleptic malignant syndrome (NMS) after the treatment of risperidone without elevated creatine kinase (CK) levels."3.96Coexistence of guanidinoacetate methyltransferase (GAMT) deficiency and neuroleptic malignant syndrome without creatine kinase elevation. ( Ayanoğlu, M; Aydin, HI; Korgali, E; Sezer, T; Sönmez, FM, 2020)
"To describe a cohort of young users of risperidone and quetiapine in the province of Manitoba (Canada) and assess the risk for movement disorders in the two treatments."3.85Movement Disorders in Children and Adolescents Receiving Antipsychotic Pharmacotherapy: A Population-Based Study. ( Alessi-Severini, S; Biscontri, RG; Bugden, S; Collins, DM; Jha, S; Katz, LY, 2017)
"Antipsychotic drugs have been used in the treatment of schizophrenia and their long-term use can cause movement disorders, such as tardive dyskinesia (TD) in humans mainly typical ones such as haloperidol."3.83Alteration of Cytokines Levels in the Striatum of Rats: Possible Participation in Vacuous Chewing Movements Induced by Antipsycotics. ( De Freitas, CM; Duarte, MM; Fachinetto, R; Ferrari, MC; Leal, CQ; Peroza, LR; Schaffer, LF, 2016)
" In the present study we investigated the influence of two common MDR1 polymorphisms on the improvement of psychopathological symptoms and occurrence of extrapyramidal side effects (EPS) in Slovenian schizophrenia patients acutely treated with risperidone."3.76MDR1 gene polymorphisms and response to acute risperidone treatment. ( Dolzan, V; Grabnar, I; Kastelic, M; Koprivsek, J; Locatelli, I; Mandelli, L; Plesnicar, BK; Serretti, A, 2010)
"This case report documents the response of a young, first-episode, neuroleptic naive male with severe catatonic schizophrenia to the novel antipsychotic, risperidone."3.70Acute and longer-term effects of risperidone in a case of first-episode catatonic schizophrenia. ( Caudle, C; Kopala, LC, 1998)
" The results from the literature underline the necessity of caution and patient monitoring when risperidone dosing is modified during methylphenidate therapy."2.72Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance. ( Burden, AM; Stämpfli, D; Weiler, S, 2021)
"RLAI and OP show good short- and long-term safety when treating patients with schizophrenia, with uncommon discontinuation due to adverse effects."2.46Long-acting atypical injectable antipsychotics in the treatment of schizophrenia: safety and tolerability review. ( Cañas, F; Möller, HJ, 2010)
"A large cohort of 1528 patients with parkinsonism was analyzed, gathering data on demography, motor and non-motor characteristics, as well as the final etiologic diagnoses based on established criteria."1.36The differential diagnoses of parkinsonism: findings from a cohort of 1528 patients and a 10 years comparison in tertiary movement disorders clinics. ( Munhoz, RP; Teive, HA; Werneck, LC, 2010)
"Aripiprazole is a novel, third-generation antipsychotic with comparable efficacy to SGAs, but a more favorable side effect profile."1.36Aripiprazole as a viable alternative for treating delusions of parasitosis. ( Bhutani, T; Busse, KL; Koo, JY; Ladizinski, B, 2010)
"Central pontine and extrapontine myelinolysis (CPEM) are rare conditions usually associated with rapid correction of hyponatremia."1.34Psychotic disorder in a patient with central and extrapontine myelinolysis. ( Krystal, A; Lim, L, 2007)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (6.06)18.2507
2000's11 (33.33)29.6817
2010's18 (54.55)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Ayanoğlu, M1
Korgali, E1
Sezer, T1
Aydin, HI1
Sönmez, FM1
Stämpfli, D1
Weiler, S1
Burden, AM1
Biscontri, RG1
Jha, S1
Collins, DM1
Bugden, S1
Katz, LY1
Alessi-Severini, S1
Chatterjee, B1
Sharan, P1
Kruse, JL1
Davis, MC1
Saddichha, S1
Talukdar, D1
Gopal, S1
Xu, H1
Bossie, C1
Burón, JA1
Fu, DJ1
Savitz, A1
Nuamah, I1
Hough, D1
Alblowi, MA1
Alosaimi, FD1
Peroza, LR1
Schaffer, LF1
De Freitas, CM1
Leal, CQ1
Ferrari, MC1
Duarte, MM1
Fachinetto, R1
Thomas Antérion, C1
Convers, P1
Desmales, S1
Borg, C1
Laurent, B1
Kastelic, M1
Koprivsek, J1
Plesnicar, BK1
Serretti, A1
Mandelli, L1
Locatelli, I1
Grabnar, I1
Dolzan, V1
Munhoz, RP1
Werneck, LC1
Teive, HA1
Cañas, F1
Möller, HJ1
Caroff, SN1
Davis, VG1
Miller, DD1
Davis, SM1
Rosenheck, RA3
McEvoy, JP1
Campbell, EC1
Saltz, BL1
Riggio, S1
Chakos, MH1
Swartz, MS1
Keefe, RS1
Stroup, TS1
Lieberman, JA1
Suzuki, T1
Takeuchi, H1
Watanabe, K1
Ladizinski, B1
Busse, KL1
Bhutani, T1
Koo, JY1
Pringsheim, T1
Kovacs, N1
Balas, I1
Janszky, J1
Simon, M1
Fekete, S1
Komoly, S1
Chrisphonte, P1
Ostroff, RB1
Gadit, A1
Kim, SW1
Chung, YC1
Lee, YH1
Lee, JH1
Kim, SY1
Bae, KY1
Kim, JM1
Shin, IS1
Yoon, JS1
Harvey, PD1
Green, MF1
McGurk, SR1
Meltzer, HY1
Karakurum, B1
Karatas, M1
Yildirim, T1
Turner, M1
Eerdekens, E1
Jacko, M1
Eerdekens, M1
Erickson, CA1
Stigler, KA1
Posey, DJ1
McDougle, CJ1
Lim, L1
Krystal, A1
Evidente, VG1
Gwinn-Hardy, K1
Caviness, JN1
Alder, CH1
Glazer, WM1
Conley, RR1
Masand, PS1
Kopala, LC1
Caudle, C1
Friedlander, R1
Lazar, S1
Klancnik, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparative Effectiveness of Antipsychotic Medications in Patients With Schizophrenia (CATIE Schizophrenia Trial)[NCT00014001]Phase 41,600 participants Interventional2000-12-31Completed
Effect of Varenicline on Smoking Cessation in Patients With Schizophrenia: Evaluation of Antipsychotic Drug-Induced Neurological Symptoms as Correlates of Response[NCT03495024]Phase 410 participants (Anticipated)Interventional2019-01-01Recruiting
Paliperidone ER Versus Risperidone for Neurocognitive Function in Patients With Schizophrenia: a Randomized, Open-label, Controlled Trial[NCT00827840]Phase 458 participants (Actual)Interventional2008-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for risperidone and Movement Disorders

ArticleYear
Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance.
    European child & adolescent psychiatry, 2021, Volume: 30, Issue:7

    Topics: Attention Deficit Disorder with Hyperactivity; Combined Modality Therapy; Comorbidity; Conduct Disor

2021
Long-acting atypical injectable antipsychotics in the treatment of schizophrenia: safety and tolerability review.
    Expert opinion on drug safety, 2010, Volume: 9, Issue:5

    Topics: Administration, Oral; Antipsychotic Agents; Benzodiazepines; Delayed-Action Preparations; Dyslipidem

2010
Open forum: effectiveness versus efficacy of second-generation antipsychotics: haloperidol without anticholinergics as a comparator.
    Psychiatric services (Washington, D.C.), 2005, Volume: 56, Issue:1

    Topics: Antipsychotic Agents; Cholinergic Antagonists; Clinical Trials as Topic; Depression; Female; Haloper

2005
Risperidone in pervasive developmental disorders.
    Expert review of neurotherapeutics, 2005, Volume: 5, Issue:6

    Topics: Antipsychotic Agents; Child; Child Development Disorders, Pervasive; Diabetes Mellitus; Expert Testi

2005
Extrapyramidal side effects, tardive dyskinesia, and the concept of atypicality.
    The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 3

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Brain; Clozapine; Dibenzothiazepines;

2000
Risperidone side effects.
    The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 8

    Topics: Antipsychotic Agents; Benzodiazepines; Drug Administration Schedule; Humans; Hyperprolactinemia; Inc

2000

Trials

4 trials available for risperidone and Movement Disorders

ArticleYear
Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Dibenzothiazepines; Female; H

2011
Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Dibenzothiazepines; Female; H

2011
Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Dibenzothiazepines; Female; H

2011
Treatment outcomes of patients with tardive dyskinesia and chronic schizophrenia.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Dibenzothiazepines; Female; H

2011
Paliperidone ER versus risperidone for neurocognitive function in patients with schizophrenia: a randomized, open-label, controlled trial.
    International clinical psychopharmacology, 2012, Volume: 27, Issue:5

    Topics: Adolescent; Adult; Antipsychotic Agents; Cognition Disorders; Delayed-Action Preparations; Depressio

2012
Changes in cognitive functioning with risperidone and olanzapine treatment: a large-scale, double-blind, randomized study.
    Psychopharmacology, 2003, Volume: 169, Issue:3-4

    Topics: Adolescent; Adult; Arousal; Benzodiazepines; Cognition Disorders; Diagnostic and Statistical Manual

2003
Long-acting injectable risperidone: safety and efficacy in stable patients switched from conventional depot antipsychotics.
    International clinical psychopharmacology, 2004, Volume: 19, Issue:4

    Topics: Adult; Antipsychotic Agents; Clopenthixol; Delayed-Action Preparations; Dose-Response Relationship,

2004

Other Studies

23 other studies available for risperidone and Movement Disorders

ArticleYear
Coexistence of guanidinoacetate methyltransferase (GAMT) deficiency and neuroleptic malignant syndrome without creatine kinase elevation.
    Brain & development, 2020, Volume: 42, Issue:5

    Topics: Child; Creatine Kinase; Dopamine Antagonists; Guanidinoacetate N-Methyltransferase; Humans; Language

2020
Movement Disorders in Children and Adolescents Receiving Antipsychotic Pharmacotherapy: A Population-Based Study.
    Journal of child and adolescent psychopharmacology, 2017, Volume: 27, Issue:10

    Topics: Adolescent; Antipsychotic Agents; Basal Ganglia Diseases; Child; Cohort Studies; Female; Humans; Mal

2017
Tardive dyskinesia in a pregnant woman with low dose, short-duration risperidone: possible role of estrogen-induced dopaminergic hypersensitivity.
    The Journal of neuropsychiatry and clinical neurosciences, 2014,Winter, Volume: 26, Issue:1

    Topics: Adult; Bipolar Disorder; Dopamine Antagonists; Estrogens; Female; Humans; Movement Disorders; Pregna

2014
New-onset extrapyramidal symptoms following oxcarbazepine discontinuation in a child receiving risperidone.
    Journal of child and adolescent psychopharmacology, 2014, Volume: 24, Issue:3

    Topics: Antipsychotic Agents; Carbamazepine; Child; Drug Interactions; Drug Therapy, Combination; Humans; Ma

2014
Serpentine tongue syndrome associated with risperidone long-acting injection treatment.
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:5

    Topics: Antipsychotic Agents; Humans; Male; Middle Aged; Movement Disorders; Risperidone; Syndrome; Tongue

2014
Incidence of tardive dyskinesia: a comparison of long-acting injectable and oral paliperidone clinical trial databases.
    International journal of clinical practice, 2014, Volume: 68, Issue:12

    Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-B

2014
Tardive dyskinesia occurring in a young woman after withdrawal of an atypical antipsychotic drug.
    Neurosciences (Riyadh, Saudi Arabia), 2015, Volume: 20, Issue:4

    Topics: Adult; Antipsychotic Agents; Female; Humans; Movement Disorders; Psychotic Disorders; Risperidone; S

2015
Alteration of Cytokines Levels in the Striatum of Rats: Possible Participation in Vacuous Chewing Movements Induced by Antipsycotics.
    Neurochemical research, 2016, Volume: 41, Issue:9

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Corpus Striatum; Cytokines; Haloperidol; Male; Move

2016
An odd manifestation of the Capgras syndrome: loss of familiarity even with the sexual partner.
    Neurophysiologie clinique = Clinical neurophysiology, 2008, Volume: 38, Issue:3

    Topics: Aged; Amnesia; Antipsychotic Agents; Atrophy; Brain; Capgras Syndrome; Donepezil; Hallucinations; Hu

2008
MDR1 gene polymorphisms and response to acute risperidone treatment.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Mar-17, Volume: 34, Issue:2

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Me

2010
The differential diagnoses of parkinsonism: findings from a cohort of 1528 patients and a 10 years comparison in tertiary movement disorders clinics.
    Clinical neurology and neurosurgery, 2010, Volume: 112, Issue:5

    Topics: Aged; Antipsychotic Agents; Cinnarizine; Cohort Studies; Diagnosis, Differential; Female; Flunarizin

2010
Is there a real difference in severity of tardive dyskinesia between risperidone and olanzapine?
    The Journal of clinical psychiatry, 2010, Volume: 71, Issue:11

    Topics: Antipsychotic Agents; Benzodiazepines; Humans; Movement Disorders; Olanzapine; Psychotic Disorders;

2010
Aripiprazole as a viable alternative for treating delusions of parasitosis.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:12

    Topics: Aged, 80 and over; Antipsychotic Agents; Aripiprazole; Delusions; Female; Humans; Mental Disorders;

2010
Missed diagnosis of tardive dystonia in an adolescent girl treated with risperidone.
    Journal of child and adolescent psychopharmacology, 2011, Volume: 21, Issue:2

    Topics: Adolescent; Antipsychotic Agents; Delayed Diagnosis; Female; Humans; Movement Disorders; Risperidone

2011
Status dystonicus in tardive dystonia successfully treated by bilateral deep brain stimulation.
    Clinical neurology and neurosurgery, 2011, Volume: 113, Issue:9

    Topics: Adolescent; Antipsychotic Agents; Clonazepam; Deep Brain Stimulation; Disability Evaluation; Electro

2011
Perphenazine suspension: a new, old treatment, side effects and continuous use.
    The Psychiatric quarterly, 2012, Volume: 83, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Cholinergic Antagonists; Clinical Trials as Topic; Dru

2012
Risperidone associated tardive dyskinesia--a less common phenomenon.
    BMJ case reports, 2011, Sep-04, Volume: 2011

    Topics: Anxiety; Depression; Humans; Male; Middle Aged; Movement Disorders; Risperidone; Serotonin Antagonis

2011
Risperidone as an alternative treatment for paroxysmal kinesigenic dyskinesia.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2003, Volume: 24, Issue:2

    Topics: Antipsychotic Agents; Brain Neoplasms; Chorea; Complementary Therapies; Female; Hematoma; Humans; Ma

2003
Psychotic disorder in a patient with central and extrapontine myelinolysis.
    Psychiatry and clinical neurosciences, 2007, Volume: 61, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Antiparkinson Agents; Antipsychotic Agents; Baclofen; Fema

2007
Risperidone is effective in severe hemichorea/hemiballismus.
    Movement disorders : official journal of the Movement Disorder Society, 1999, Volume: 14, Issue:2

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Chorea; Dopamine Antagonists; Female; Humans; Movemen

1999
Side effects of antipsychotics in the elderly.
    The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 8

    Topics: Age Factors; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Clinical Trials as Topic; Clozapine

2000
Acute and longer-term effects of risperidone in a case of first-episode catatonic schizophrenia.
    Journal of psychopharmacology (Oxford, England), 1998, Volume: 12, Issue:3

    Topics: Adolescent; Antipsychotic Agents; Humans; Male; Movement Disorders; Psychiatric Status Rating Scales

1998
Atypical antipsychotic use in treating adolescents and young adults with developmental disabilities.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2001, Volume: 46, Issue:8

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Intellectual Disability; M

2001