Page last updated: 2024-11-03

risperidone and Intellectual Disability

risperidone has been researched along with Intellectual Disability in 83 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Research Excerpts

ExcerptRelevanceReference
"62 subjects with intellectual disability underwent to a 2-arm, parallel group pragmatic trial of olanzapine and risperidone with balanced randomisation and blind assessment of outcome at 4, 8, 12, 16, 20 and 24 weeks after a switch (cross-tapering) from a 24-week treatment with FGAs."9.15Olanzapine vs. risperidone in treating aggressive behaviours in adults with intellectual disability: a single blind study. ( Amore, M; Bertelli, M; Rossi, M; Tamborini, S; Villani, D, 2011)
"We report on an open-label, naturalistic study using risperidone to treat disruptive behaviors and self-injury in children with Down syndrome, severe intellectual disability, and comorbid autism spectrum disorders (DS+ASDs)."9.13Risperidone use in children with Down syndrome, severe intellectual disability, and comorbid autistic spectrum disorders: a naturalistic study. ( Capone, GT; Goyal, P; Grados, M; Kammann, H; Smith, B, 2008)
"As part of an ongoing, prospective, ABA design, double-blind crossover study of risperidone versus placebo for the treatment of aggressive, destructive and self-injurious behavior in persons aged 6-65 years with mental retardation (MR) and autism, we measured the weight of 19 subjects at each study visit."9.09Weight gain in a controlled study of risperidone in children, adolescents and adults with mental retardation and autism. ( Crandall, K; Hellings, JA; Schroeder, SR; Wallace, D; Zarcone, JR, 2001)
"We randomly assigned 38 adolescents (33 boys; 10 subjects with slightly subaverage IQ, 14 with borderline IQ, and 14 with mild mental retardation), who were hospitalized for treatment of psychiatric disorders associated with severe aggression, to receive risperidone or placebo."9.09A randomized controlled trial of risperidone in the treatment of aggression in hospitalized adolescents with subaverage cognitive abilities. ( Buitelaar, JK; Cohen-Kettenis, P; Melman, CT; van der Gaag, RJ, 2001)
" The Special Topic Advisory Panel on Transitioning to Risperidone Therapy in Patients With Mental Retardation and Developmental Disabilities comprised academic clinicians with at least 10 years' experience in the field of mental retardation and developmental disabilities."8.82Treatment of behavior disorders in mental retardation: report on transitioning to atypical antipsychotics, with an emphasis on risperidone. ( Aman, MG; Gharabawi, GM, 2004)
"Risperidone is a widely used, second-generation antipsychotic approved for treating schizophrenia as well as for treating aggression in children and adolescents with mental retardation."7.85Mild Hypothermia in a Child with Low-Dose Risperidone. ( Denzer, C; Freudenmann, RW; Gahr, M; Grau, K; Plener, PL, 2017)
"A patient with comorbid intellectual disability, catatonic schizophrenia, and recurrent oneiroid state of consciousness improved on long-acting risperidone and remains well at the three-year follow-up."7.81Effectiveness of long-acting risperidone in a patient with comorbid intellectual disability, catatonic schizophrenia, and oneiroid syndrome. ( Alessi, MC; Angeletti, G; Callovini, G; Criscuolo, S; Del Casale, A; Ferri, VR; Girardi, P; Janiri, D; Kotzalidis, GD; Massolo, AC; Rapinesi, C; Serata, D, 2015)
"We report several cases in which patients with autistic disorder with mental retardation who received risperidone experienced urinary incontinence."7.80Risperidone-associated urinary incontinence in patients with autistic disorder with mental retardation. ( Imasaka, Y; Iwata, K; Kumazaki, H; Mimura, M; Tomoda, A; Watanabe, K, 2014)
"Two children aged 11 and 10 years, diagnosed with autism and mental retardation, have developed new-onset diurnal and nocturnal enuresis respectively on their first and second weeks of risperidone monotherapy (1."7.74Risperidone-induced enuresis in two children with autistic disorder. ( Hergüner, S; Mukaddes, NM, 2007)
"We present a patient with juvenile neuronal ceroid lipofuscinosis who developed a neuroleptic malignant syndrome when treated for hallucinations with a very low dose of risperidone, an atypical neuroleptic medication with usually few extrapyramidal side-effects."7.72Neuroleptic malignant syndrome in juvenile neuronal ceroid lipofuscinosis associated with low-dose risperidone therapy. ( Buyse, GM; Proost, JE; Van Hove, JL; Vercammen, L, 2003)
"The current investigation lends support to data that note weight gain with risperidone in adults with mental retardation."7.71Weight gain with risperidone among patients with mental retardation: effect of calorie restriction. ( Cohen, S; Glazewski, R; Khan, A; Khan, S, 2001)
"Young patients with intellectual disability (ID) have both diagnostic and therapeutic challenges."5.72Top-Up Clozapine for Risperidone LAI-Related Acute Dystonia and TR Bipolar in an Adolescent with ID- ( Alamiri, B; Naguy, A; Pridmore, S; Singh, A, 2022)
"Risperidone has proven efficacy with reduced likelihood of causing extrapyramidal symptoms in the treatment of schizophrenia."5.30Risperidone for aggression and self-injurious behavior in adults with mental retardation. ( Cohen, SA; Ihrig, K; Kerrick, JM; Lott, RS, 1998)
"Many autistic patients with mental retardation have difficulties with explosivity and aggression."5.30Risperidone and explosive aggressive autism. ( Barnhill, LJ; Horrigan, JP, 1997)
"62 subjects with intellectual disability underwent to a 2-arm, parallel group pragmatic trial of olanzapine and risperidone with balanced randomisation and blind assessment of outcome at 4, 8, 12, 16, 20 and 24 weeks after a switch (cross-tapering) from a 24-week treatment with FGAs."5.15Olanzapine vs. risperidone in treating aggressive behaviours in adults with intellectual disability: a single blind study. ( Amore, M; Bertelli, M; Rossi, M; Tamborini, S; Villani, D, 2011)
"We report on an open-label, naturalistic study using risperidone to treat disruptive behaviors and self-injury in children with Down syndrome, severe intellectual disability, and comorbid autism spectrum disorders (DS+ASDs)."5.13Risperidone use in children with Down syndrome, severe intellectual disability, and comorbid autistic spectrum disorders: a naturalistic study. ( Capone, GT; Goyal, P; Grados, M; Kammann, H; Smith, B, 2008)
"The results of this post hoc analysis of affective symptoms of DBDs using data from a previously published randomized, double-blind clinical comparison of risperidone and placebo in the treatment of children with DBDs and subaverage intelligence suggest that risperidone was effective in treating the factors of explosive irritability; agitated, expansive, grandiose; and depression."5.12Risperidone for the treatment of affective symptoms in children with disruptive behavior disorder: a post hoc analysis of data from a 6-week, multicenter, randomized, double-blind, parallel-arm study. ( Biederman, J; Faraone, SV; Mick, E; Pandina, G; Spencer, T; Wozniak, J, 2006)
"To determine whether risperidone is effective in reducing symptoms of disruptive behaviors (such as aggression, impulsivity, defiance of authority figures, and property destruction) associated with conduct disorder, oppositional defiant disorder, and disruptive behavior disorder-not otherwise specified in children with subaverage IQs."5.10Effects of risperidone on conduct and disruptive behavior disorders in children with subaverage IQs. ( Aman, M; Binder, C; Carroll, A; Fisman, S; Snyder, R; Turgay, A, 2002)
"As part of an ongoing, prospective, ABA design, double-blind crossover study of risperidone versus placebo for the treatment of aggressive, destructive and self-injurious behavior in persons aged 6-65 years with mental retardation (MR) and autism, we measured the weight of 19 subjects at each study visit."5.09Weight gain in a controlled study of risperidone in children, adolescents and adults with mental retardation and autism. ( Crandall, K; Hellings, JA; Schroeder, SR; Wallace, D; Zarcone, JR, 2001)
"We randomly assigned 38 adolescents (33 boys; 10 subjects with slightly subaverage IQ, 14 with borderline IQ, and 14 with mild mental retardation), who were hospitalized for treatment of psychiatric disorders associated with severe aggression, to receive risperidone or placebo."5.09A randomized controlled trial of risperidone in the treatment of aggression in hospitalized adolescents with subaverage cognitive abilities. ( Buitelaar, JK; Cohen-Kettenis, P; Melman, CT; van der Gaag, RJ, 2001)
"Antipsychotics, particularly risperidone, appear to be effective in reducing problem behaviors in children with intellectual disability."4.93Pharmacotherapy for mental health problems in people with intellectual disability. ( Findling, RL; Ji, NY, 2016)
" The Special Topic Advisory Panel on Transitioning to Risperidone Therapy in Patients With Mental Retardation and Developmental Disabilities comprised academic clinicians with at least 10 years' experience in the field of mental retardation and developmental disabilities."4.82Treatment of behavior disorders in mental retardation: report on transitioning to atypical antipsychotics, with an emphasis on risperidone. ( Aman, MG; Gharabawi, GM, 2004)
"Risperidone is a widely used, second-generation antipsychotic approved for treating schizophrenia as well as for treating aggression in children and adolescents with mental retardation."3.85Mild Hypothermia in a Child with Low-Dose Risperidone. ( Denzer, C; Freudenmann, RW; Gahr, M; Grau, K; Plener, PL, 2017)
"A patient with comorbid intellectual disability, catatonic schizophrenia, and recurrent oneiroid state of consciousness improved on long-acting risperidone and remains well at the three-year follow-up."3.81Effectiveness of long-acting risperidone in a patient with comorbid intellectual disability, catatonic schizophrenia, and oneiroid syndrome. ( Alessi, MC; Angeletti, G; Callovini, G; Criscuolo, S; Del Casale, A; Ferri, VR; Girardi, P; Janiri, D; Kotzalidis, GD; Massolo, AC; Rapinesi, C; Serata, D, 2015)
"We report several cases in which patients with autistic disorder with mental retardation who received risperidone experienced urinary incontinence."3.80Risperidone-associated urinary incontinence in patients with autistic disorder with mental retardation. ( Imasaka, Y; Iwata, K; Kumazaki, H; Mimura, M; Tomoda, A; Watanabe, K, 2014)
"Two children aged 11 and 10 years, diagnosed with autism and mental retardation, have developed new-onset diurnal and nocturnal enuresis respectively on their first and second weeks of risperidone monotherapy (1."3.74Risperidone-induced enuresis in two children with autistic disorder. ( Hergüner, S; Mukaddes, NM, 2007)
"Atypical antipsychotics, especially clozapine and olanzapine, have been increasingly associated with weight gain and other adverse metabolic events (diabetes mellitus, hyperlipidemia) in non-mentally retarded populations."3.73Metabolic effects associated with atypical antipsychotic treatment in the developmentally disabled. ( Ball, MP; Bodfish, JW; Heeth, WL; Mahorney, SL; McKee, JR, 2005)
"We present a patient with juvenile neuronal ceroid lipofuscinosis who developed a neuroleptic malignant syndrome when treated for hallucinations with a very low dose of risperidone, an atypical neuroleptic medication with usually few extrapyramidal side-effects."3.72Neuroleptic malignant syndrome in juvenile neuronal ceroid lipofuscinosis associated with low-dose risperidone therapy. ( Buyse, GM; Proost, JE; Van Hove, JL; Vercammen, L, 2003)
"The current investigation lends support to data that note weight gain with risperidone in adults with mental retardation."3.71Weight gain with risperidone among patients with mental retardation: effect of calorie restriction. ( Cohen, S; Glazewski, R; Khan, A; Khan, S, 2001)
"In people with intellectual disability (ID) and challenging behaviour, antipsychotics (AP) are often used off-label and for a long period."3.01Antipsychotics withdrawal in adults with intellectual disability and challenging behaviour: study protocol for a multicentre double-blind placebo-controlled randomised trial. ( Beumer, S; Hamers, P; Maes-Festen, D; Oppewal, A, 2021)
"Risperidone has shown safety and efficacy for aggressive and destructive behaviors in short-term studies."2.72A crossover study of risperidone in children, adolescents and adults with mental retardation. ( Fleming, KK; Hellings, JA; Marquis, JG; Reese, RM; Schroeder, SR; Valdovinos, MG; Zarcone, JR, 2006)
"Risperidone was also associated with significantly greater improvement than placebo on all other Nisonger Child Behavior Rating Form subscales at endpoint, as well as on the Aberrant Behavior Checklist subscales for irritability, lethargy/social withdrawal, and hyperactivity; the Behavior Problems Inventory aggressive/destructive behavior subscale; a visual analogue scale of the most troublesome symptom; and the Clinical Global Impression change score."2.70Double-blind, placebo-controlled study of risperidone for the treatment of disruptive behaviors in children with subaverage intelligence. ( Aman, MG; De Smedt, G; Derivan, A; Findling, RL; Lyons, B, 2002)
"Risperidone was given in daily doses ranging from 0."2.69Open-label treatment with risperidone of 26 psychiatrically-hospitalized children and adolescents with mixed diagnoses and aggressive behavior. ( Buitelaar, JK, 2000)
"Risperidone (1-8 mg/day) was associated with a 50 percent or greater reduction in at least one target behavior frequency in 61 percent of patients."2.68Clinical and economic aspects of risperidone treatment in adults with mental retardation and behavioral disturbance. ( Cohen, SA; Kerrick, JM; Lott, RS, 1996)
"Risperidone was significantly superior to placebo in its effect on the Aberrant Behaviour Checklist and the Clinical Global Impression."2.67Risperidone as add-on therapy in behavioural disturbances in mental retardation: a double-blind placebo-controlled cross-over study. ( Buttiëns, M; Dierick, G; Geutjens, J; Heylen, S; Sieben, G; Thiry, P; Vanden Borre, R; Vermote, R, 1993)
"Probably pseudohypoaldosteronism was a coincidental finding in this girl with a CDK13 mutation, but because only limited information is known about CDK13-related disorders, further investigation could be more informative to clarify this presentation."2.61One-month-old girl presenting with pseudohypoaldosteronism leading to the diagnosis of CDK13-related disorder: a case report and review of the literature. ( Ayman, A; Kremer, AK; van den Akker, M; Yakubov, R, 2019)
" They responded well to the reduction in dosage or to withdrawal of the apparent causing agent."2.49[Medication-related oculogyric crises: a description of four cases and a review of the literature]. ( Campistol, J; Darling, A; Perez-Duenas, B; Poo, P, 2013)
" Although there are some reports in literature, the side effect profile in this population remains poorly defined and there is a need to raise awareness among clinicians across specialties."1.91Recognising side effects of antipsychotics in children with intellectual disabilities. ( Anand, G; Lee, J; Shepperd, R; Smith, M, 2023)
"Young patients with intellectual disability (ID) have both diagnostic and therapeutic challenges."1.72Top-Up Clozapine for Risperidone LAI-Related Acute Dystonia and TR Bipolar in an Adolescent with ID- ( Alamiri, B; Naguy, A; Pridmore, S; Singh, A, 2022)
"There were significant gaps in adverse effect monitoring in this cohort."1.51Adherence to Antipsychotic Adverse Effect Monitoring Among a Referred Sample of Children with Intellectual Disabilities. ( Javaheri, KR; McLennan, JD, 2019)
"A 55-year-old woman with a history of mental retardation and infantile psychosis is hospitalized for worsening of her psychiatric symptoms."1.43[Case report: Neuroleptic malignant syndrome and diagnostic difficulties]. ( Khouri, C; Logerot, S; Mallaret, M; Planès, S; Villier, C, 2016)
"She also exhibited precocious puberty and growth hormone deficiency and required treatment for improving final height."1.40Endocrinological anomalies in a patient with 12q14 microdeletion syndrome. Completing phenotype of this exceptional short stature condition. ( Marco, FC; Nso-Roca, AP; Ricote, JM; Ruiz, MJ, 2014)
"The patient had profound mental retardation, had an IQ in the range of less than 20 to 25, and was nonverbal."1.34Risperidone for the treatment of fecal smearing in a developmentally disabled adult. ( Brahm, NC; Brown, RC; Farmer, KC, 2007)
" During the subsequent week, rates of problem behavior typically decreased without reinstating the prior dosage of medication."1.34Temporary increases in problem behavior and sleep disruption following decreases in medication: a descriptive analysis of conditional rates. ( Dornbusch, K; Rapp, JT; Swanson, G, 2007)
"The structural background of mental retardation, the function of the affected cerebral structures, is not completely clarified."1.32[Experience with Risperidone in the treatment of institutionalized mentally retarded patients, with special reference to treatment of aggressive states]. ( Fehér, L; Hal, V, 2004)
""B" was an 11-year-old girl with mild mental retardation and aggression who was treated with risperidone 1 mg per day."1.32Risperidone-induced obsessive-compulsive symptoms in two children. ( Avci, A; Diler, RS; Scahill, L; Yolga, A, 2003)
"Risperidone was able to reduce the aggressive behavior in this patient."1.31Risperidone for controlling aggressive behavior in a mentally retarded child: a case report. ( Intaprasert, S; Maneeton, N; Srisurapanont, M, 2001)
"Many autistic patients with mental retardation have difficulties with explosivity and aggression."1.30Risperidone and explosive aggressive autism. ( Barnhill, LJ; Horrigan, JP, 1997)
"Weight gain was observed in 5 of 6 patients, with a median increase of 5."1.30Risperidone in children and adolescents with pervasive developmental disorder: pilot trial and follow-up. ( Armenteros, J; Munoz-Silva, DM; Pataki, C; Perry, R; Silva, RR, 1997)
"Risperidone has proven efficacy with reduced likelihood of causing extrapyramidal symptoms in the treatment of schizophrenia."1.30Risperidone for aggression and self-injurious behavior in adults with mental retardation. ( Cohen, SA; Ihrig, K; Kerrick, JM; Lott, RS, 1998)

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (14.46)18.2507
2000's39 (46.99)29.6817
2010's27 (32.53)24.3611
2020's5 (6.02)2.80

Authors

AuthorsStudies
Beumer, S1
Hamers, P1
Oppewal, A1
Maes-Festen, D1
Naguy, A1
Pridmore, S1
Singh, A1
Alamiri, B1
Hodgins, GE1
Winsor, K1
Barnhill, J1
Lee, J1
Shepperd, R1
Smith, M1
Anand, G1
Yakubov, R1
Ayman, A1
Kremer, AK1
van den Akker, M1
Espadas, C1
Ballester, P1
Londoño, AC1
Almenara, S1
Aguilar, V1
Belda, C1
Pérez, E1
Peiró, AM1
Lambrechts, S1
Devriendt, K1
Vogels, A1
Ramerman, L2
Hoekstra, PJ2
de Kuijper, G2
Scheers, T1
Vink, M1
Vrijmoeth, P1
Javaheri, KR1
McLennan, JD1
Gnanavel, S1
Nso-Roca, AP1
Marco, FC1
Ricote, JM1
Ruiz, MJ1
Adler, BA1
Wink, LK1
Early, M1
Shaffer, R1
Minshawi, N1
McDougle, CJ3
Erickson, CA1
Kumazaki, H1
Watanabe, K1
Imasaka, Y1
Iwata, K1
Tomoda, A1
Mimura, M1
Kiliçaslan, F1
Bayazit, H1
Kandemir, H1
Çalik, M1
Kandemir, SB1
Guler, K1
Serata, D1
Rapinesi, C2
Kotzalidis, GD2
Alessi, MC1
Janiri, D1
Massolo, AC1
Ferri, VR1
Criscuolo, S1
Callovini, G1
Angeletti, G1
Girardi, P2
Del Casale, A2
Ji, NY1
Findling, RL2
Khouri, C1
Planès, S1
Logerot, S1
Villier, C1
Mallaret, M1
Sacco, M1
De Giorgi, R1
Giardini, M1
D'Andreagiovanni, M1
Carlino, N1
Brugnoli, R1
Grau, K1
Plener, PL1
Gahr, M1
Denzer, C1
Freudenmann, RW1
Scahill, L2
Aman, MG3
McCracken, JT1
Vitiello, B1
Pasini, A1
D'Agati, E1
Casarelli, L1
Curatolo, P1
Romeo, R1
Knapp, M2
Tyrer, P2
Crawford, M1
Oliver-Africano, P2
Dickens, S1
Ahmed, Z1
Bouras, N2
Cooray, S1
Deb, S1
Hare, M1
Meade, M1
Reece, B1
Bhaumik, S1
Harley, D1
Piachaud, J1
Regan, A1
Ade Thomas, D1
Karatela, S1
Rao, B1
Dzendrowskyj, T1
Lenôtre, L1
Watson, J1
Valdovinos, MG3
Bailey, L1
Taylor, SL1
Amore, M1
Bertelli, M1
Villani, D1
Tamborini, S1
Rossi, M1
Janowsky, DS1
Hu, Q1
Buneviciute, J1
Davis, JM1
Budisteanu, M1
Papuc, SM1
Tutulan-Cunita, A1
Budisteanu, B1
Arghir, A1
Usta, MG1
Tufan, AE1
Cüceloğlu, EA1
Gandal, MJ1
Sisti, J1
Klook, K1
Ortinski, PI1
Leitman, V1
Liang, Y1
Thieu, T1
Anderson, R1
Pierce, RC1
Jonak, G1
Gur, RE1
Carlson, G1
Siegel, SJ1
Sharma, V1
Biswas, DD1
Banga, A1
Connor, DF1
Pringsheim, T1
Gorman, D1
Darling, A1
Poo, P1
Perez-Duenas, B1
Campistol, J1
De Smedt, G1
Derivan, A1
Lyons, B1
Turgay, A2
Binder, C2
Snyder, R2
Fisman, S2
Aman, M2
Carroll, A1
Levitas, A1
Yoo, JH1
Williams, DC1
Napolitano, DA1
Peyton, RT1
Baer, DM1
Schroeder, SR6
Diler, RS1
Yolga, A1
Avci, A1
Vercammen, L1
Buyse, GM1
Proost, JE1
Van Hove, JL1
Mosolov, SN1
Kabanov, SO1
Hal, V1
Fehér, L1
Gharabawi, GM1
Correia Filho, AG1
Bodanese, R1
Silva, TL1
Alvares, JP1
Rohde, LA1
McKee, JR1
Bodfish, JW1
Mahorney, SL1
Heeth, WL1
Ball, MP1
Hellings, JA4
Zarcone, JR4
Reese, RM3
Gaughan, E1
Marquis, JG1
Fleming, KK1
Reyes, M1
Croonenberghs, J1
Augustyns, I1
Eerdekens, M1
Biederman, J1
Mick, E1
Faraone, SV1
Wozniak, J1
Spencer, T1
Pandina, G1
Brahm, NC1
Farmer, KC1
Brown, RC1
Hergüner, S2
Mukaddes, NM2
Niederhofer, H1
Rapp, JT1
Swanson, G1
Dornbusch, K1
Matson, JL1
Wilkins, J1
Ruedrich, SL1
Swales, TP1
Rossvanes, C1
Diana, L1
Arkadiev, V1
Lim, K1
Capone, GT1
Goyal, P1
Grados, M1
Smith, B1
Kammann, H1
Trollor, JN1
Somerville, ER1
Somerville, HM1
Purdon, SE1
Lit, W1
Labelle, A1
Jones, BD1
Vanden Borre, R1
Vermote, R1
Buttiëns, M1
Thiry, P1
Dierick, G1
Geutjens, J1
Sieben, G1
Heylen, S1
Levin, GM1
Lazowick, AL1
Powell, HS1
Simon, EW1
Blubaugh, KM1
Pippidis, M1
Lott, RS2
Kerrick, JM2
Cohen, SA2
Horrigan, JP1
Barnhill, LJ1
Demb, HB1
Khan, BU1
Perry, R1
Pataki, C1
Munoz-Silva, DM1
Armenteros, J1
Silva, RR1
Ihrig, K1
Dartnall, NA1
Holmes, JP1
Morgan, SN1
Hässler, F2
Fegert, JM1
Buitelaar, JK2
Williams, H1
Clarke, R1
Martin, J1
Holt, G1
Cohen, S1
Glazewski, R1
Khan, S1
Khan, A1
Van Bellinghen, M1
De Troch, C1
van der Gaag, RJ1
Cohen-Kettenis, P1
Melman, CT1
Hammock, R1
Levine, WR1
Maneeton, N1
Intaprasert, S1
Srisurapanont, M1
Crandall, K2
Wallace, D1
Friedlander, R1
Lazar, S1
Klancnik, J1
Marquis, J1
Fleming, K1
Shores, R1
Williams, D1
Jagadheesan, K1
Nizamie, SH1
Buchmann, J1
Bohne, S1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Investigation of the Impact of Atypical Antipsychotics on Brain Functioning in Youths With Conduct Disorder[NCT01867398]12 participants (Actual)Observational2013-04-29Terminated
The Safety And Efficacy Of Risperidone Versus Placebo In Conduct Disorder and Other Disruptive Behavior Disorders In Mild, Moderate And Borderline Mentally Retarded Children Aged 5 To 12 Years[NCT00266552]Phase 3118 participants (Actual)InterventionalCompleted
The Safety And Efficacy Of Risperidone Versus Placebo In Conduct Disorder In Mild, Moderate And Borderline Mentally Retarded Children Aged 5 To 12 Years[NCT00250354]Phase 3110 participants (Actual)Interventional1997-09-30Completed
Severe Aberrant Behavior Among Persons With Mental Retardation. Project III: Behavioral Selectivity of Atypical Neuroleptic Drugs: Effects on Cognitive and Social Behaviors[NCT00065273]Phase 350 participants Interventional1998-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for risperidone and Intellectual Disability

ArticleYear
Pharmacotherapy of Disruptive Behaviors in Children with Intellectual Disabilities.
    Paediatric drugs, 2022, Volume: 24, Issue:5

    Topics: Aggression; Attention Deficit and Disruptive Behavior Disorders; Child; Conduct Disorder; Humans; In

2022
One-month-old girl presenting with pseudohypoaldosteronism leading to the diagnosis of CDK13-related disorder: a case report and review of the literature.
    Journal of medical case reports, 2019, Dec-29, Volume: 13, Issue:1

    Topics: CDC2 Protein Kinase; Chelating Agents; DNA Mutational Analysis; Female; Humans; Infant; Intellectual

2019
Pharmacotherapy for mental health problems in people with intellectual disability.
    Current opinion in psychiatry, 2016, Volume: 29, Issue:2

    Topics: Aggression; Anticonvulsants; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Ce

2016
Second-generation antipsychotics for the treatment of disruptive behaviour disorders in children: a systematic review.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2012, Volume: 57, Issue:12

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Child,

2012
[Medication-related oculogyric crises: a description of four cases and a review of the literature].
    Revista de neurologia, 2013, Feb-01, Volume: 56, Issue:3

    Topics: Adolescent; Anticonvulsants; Antipsychotic Agents; Aripiprazole; Child; Child Behavior Disorders; Ch

2013
[The appearance of metabolic syndrome in treatment with atypical antipsychotics].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2003, Volume: 103, Issue:11

    Topics: Adolescent; Adult; Age Factors; Aged; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Body W

2003
Treatment of behavior disorders in mental retardation: report on transitioning to atypical antipsychotics, with an emphasis on risperidone.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:9

    Topics: Adult; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Basal Ganglia Dise

2004
[Psychopharmacological therapy of self-injurious behavior in mentally retarded individuals].
    Der Nervenarzt, 1999, Volume: 70, Issue:11

    Topics: Adult; Dopamine Antagonists; Dose-Response Relationship, Drug; Humans; Intellectual Disability; Male

1999

Trials

23 trials available for risperidone and Intellectual Disability

ArticleYear
Antipsychotics withdrawal in adults with intellectual disability and challenging behaviour: study protocol for a multicentre double-blind placebo-controlled randomised trial.
    BMC psychiatry, 2021, 09-06, Volume: 21, Issue:1

    Topics: Adult; Antipsychotic Agents; Behavioral Symptoms; Double-Blind Method; Humans; Intellectual Disabili

2021
Is risperidone effective in reducing challenging behaviours in individuals with intellectual disabilities after 1 year or longer use? A placebo-controlled, randomised, double-blind discontinuation study.
    Journal of intellectual disability research : JIDR, 2019, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Child; Double-Blind Method; Drug Administration Sched

2019
The treatment of challenging behaviour in intellectual disabilities: cost-effectiveness analysis.
    Journal of intellectual disability research : JIDR, 2009, Volume: 53, Issue:7

    Topics: Adult; Aggression; Antipsychotic Agents; Combined Modality Therapy; Cost-Benefit Analysis; Double-Bl

2009
Overcoming the barriers experienced in conducting a medication trial in adults with aggressive challenging behaviour and intellectual disabilities.
    Journal of intellectual disability research : JIDR, 2010, Jan-01, Volume: 54, Issue:1

    Topics: Adult; Aggression; Antipsychotic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Evid

2010
Olanzapine vs. risperidone in treating aggressive behaviours in adults with intellectual disability: a single blind study.
    Journal of intellectual disability research : JIDR, 2011, Volume: 55, Issue:2

    Topics: Adult; Aggression; Antipsychotic Agents; Benzodiazepines; Female; Humans; Intellectual Disability; L

2011
Double-blind, placebo-controlled study of risperidone for the treatment of disruptive behaviors in children with subaverage intelligence.
    The American journal of psychiatry, 2002, Volume: 159, Issue:8

    Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Comorb

2002
Double-blind, placebo-controlled study of risperidone for the treatment of disruptive behaviors in children with subaverage intelligence.
    The American journal of psychiatry, 2002, Volume: 159, Issue:8

    Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Comorb

2002
Double-blind, placebo-controlled study of risperidone for the treatment of disruptive behaviors in children with subaverage intelligence.
    The American journal of psychiatry, 2002, Volume: 159, Issue:8

    Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Comorb

2002
Double-blind, placebo-controlled study of risperidone for the treatment of disruptive behaviors in children with subaverage intelligence.
    The American journal of psychiatry, 2002, Volume: 159, Issue:8

    Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Comorb

2002
Long-term safety and efficacy of risperidone for the treatment of disruptive behavior disorders in children with subaverage IQs.
    Pediatrics, 2002, Volume: 110, Issue:3

    Topics: Antipsychotic Agents; Child; Child Behavior Disorders; Dopamine Antagonists; Female; Humans; Intelle

2002
Effects of risperidone on conduct and disruptive behavior disorders in children with subaverage IQs.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2002, Volume: 41, Issue:9

    Topics: Analysis of Variance; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Chi

2002
Rate-decreasing effects of the atypical neuroleptic risperidone attenuated by conditions of reinforcement in a woman with mental retardation.
    Journal of applied behavior analysis, 2003,Summer, Volume: 36, Issue:2

    Topics: Adult; Antipsychotic Agents; Attention; Autistic Disorder; Behavior Therapy; Bipolar Disorder; Discr

2003
Comparison of risperidone and methylphenidate for reducing ADHD symptoms in children and adolescents with moderate mental retardation.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2005, Volume: 44, Issue:8

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys

2005
Risperidone-induced prolactin elevation in a prospective study of children, adolescents, and adults with mental retardation and pervasive developmental disorders.
    Journal of child and adolescent psychopharmacology, 2005, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Age Factors; Antipsychotic Agents; Child; Child Development Disorders, Pervasive;

2005
A crossover study of risperidone in children, adolescents and adults with mental retardation.
    Journal of autism and developmental disorders, 2006, Volume: 36, Issue:3

    Topics: Adolescent; Adult; Aggression; Antipsychotic Agents; Autistic Disorder; Child; Cross-Over Studies; D

2006
Long-term use of risperidone in children with disruptive behavior disorders and subaverage intelligence: efficacy, safety, and tolerability.
    Journal of child and adolescent psychopharmacology, 2006, Volume: 16, Issue:3

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Behavior; Child; Co

2006
Risperidone for the treatment of affective symptoms in children with disruptive behavior disorder: a post hoc analysis of data from a 6-week, multicenter, randomized, double-blind, parallel-arm study.
    Clinical therapeutics, 2006, Volume: 28, Issue:5

    Topics: Affective Symptoms; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Depre

2006
Antipsychotic drugs for aggression in intellectual disability.
    Lancet (London, England), 2008, Jan-05, Volume: 371, Issue:9606

    Topics: Aggression; Antipsychotic Agents; Haloperidol; Humans; Intellectual Disability; Risperidone

2008
Risperidone use in children with Down syndrome, severe intellectual disability, and comorbid autistic spectrum disorders: a naturalistic study.
    Journal of developmental and behavioral pediatrics : JDBP, 2008, Volume: 29, Issue:2

    Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Autistic Disorder; Central Nervous

2008
Risperidone as add-on therapy in behavioural disturbances in mental retardation: a double-blind placebo-controlled cross-over study.
    Acta psychiatrica Scandinavica, 1993, Volume: 87, Issue:3

    Topics: Adolescent; Adult; Antipsychotic Agents; Basal Ganglia Diseases; Double-Blind Method; Drug Therapy,

1993
Clinical and economic aspects of risperidone treatment in adults with mental retardation and behavioral disturbance.
    Psychopharmacology bulletin, 1996, Volume: 32, Issue:4

    Topics: Adult; Aged; Female; Humans; Intellectual Disability; Male; Mental Disorders; Middle Aged; Prognosis

1996
Open-label treatment with risperidone of 26 psychiatrically-hospitalized children and adolescents with mixed diagnoses and aggressive behavior.
    Journal of child and adolescent psychopharmacology, 2000,Spring, Volume: 10, Issue:1

    Topics: Adolescent; Aggression; Antipsychotic Agents; Child; Female; Hospitalization; Humans; Intellectual D

2000
Risperidone in the treatment of behavioral disturbances in children and adolescents with borderline intellectual functioning: a double-blind, placebo-controlled pilot trial.
    Journal of child and adolescent psychopharmacology, 2001,Spring, Volume: 11, Issue:1

    Topics: Adolescent; Adolescent Behavior; Antipsychotic Agents; Child; Child Behavior Disorders; Double-Blind

2001
A randomized controlled trial of risperidone in the treatment of aggression in hospitalized adolescents with subaverage cognitive abilities.
    The Journal of clinical psychiatry, 2001, Volume: 62, Issue:4

    Topics: Adolescent; Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; B

2001
Weight gain in a controlled study of risperidone in children, adolescents and adults with mental retardation and autism.
    Journal of child and adolescent psychopharmacology, 2001,Fall, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Aggression; Antipsychotic Agents; Autistic Disorder; Child; Cross-Over Stud

2001
Effects of risperidone on aberrant behavior of persons with developmental disabilities: I. A double-blind crossover study using multiple measures.
    American journal of mental retardation : AJMR, 2001, Volume: 106, Issue:6

    Topics: Adolescent; Adult; Aged; Aggression; Child; Cross-Over Studies; Dose-Response Relationship, Drug; Do

2001

Other Studies

52 other studies available for risperidone and Intellectual Disability

ArticleYear
Top-Up Clozapine for Risperidone LAI-Related Acute Dystonia and TR Bipolar in an Adolescent with ID-
    Psychopharmacology bulletin, 2022, 05-31, Volume: 52, Issue:2

    Topics: Adolescent; Antipsychotic Agents; Clozapine; Dystonia; Dystonic Disorders; Humans; Intellectual Disa

2022
Recognising side effects of antipsychotics in children with intellectual disabilities.
    BMJ case reports, 2023, Jan-04, Volume: 16, Issue:1

    Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Child; Drug-Related Side Effects and Adverse Reactio

2023
Multimorbidity and psychotropic polypharmacy among participants with autism spectrum disorder with intellectual disability.
    Psychiatry research, 2020, Volume: 292

    Topics: Adult; Autism Spectrum Disorder; Cohort Studies; Comorbidity; Female; Humans; Intellectual Disabilit

2020
Low-Dose Aripiprazole and Risperidone for Treating Problem Behavior in Children With Pitt-Hopkins Syndrome.
    Journal of clinical psychopharmacology, 2018, Volume: 38, Issue:3

    Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Child; Facies; Female; Humans; Hyperventilation; Int

2018
Changes in Health-Related Quality of Life in People With Intellectual Disabilities Who Discontinue Long-Term Used Antipsychotic Drugs for Challenging Behaviors.
    Journal of clinical pharmacology, 2019, Volume: 59, Issue:2

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Child; Double-Blind Method; Female; Humans; Intellect

2019
Adherence to Antipsychotic Adverse Effect Monitoring Among a Referred Sample of Children with Intellectual Disabilities.
    Journal of child and adolescent psychopharmacology, 2019, Volume: 29, Issue:3

    Topics: Adolescent; Antipsychotic Agents; Body Mass Index; Canada; Community Mental Health Services; Drug-Re

2019
Smith-Magneis syndrome: behavioural phenotype mimics ADHD.
    BMJ case reports, 2014, Jan-06, Volume: 2014

    Topics: Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Child; Combined Modality Therapy; D

2014
Endocrinological anomalies in a patient with 12q14 microdeletion syndrome. Completing phenotype of this exceptional short stature condition.
    Journal of pediatric endocrinology & metabolism : JPEM, 2014, Volume: 27, Issue:5-6

    Topics: Antipsychotic Agents; Body Height; Child; Child Behavior Disorders; Chromosome Deletion; Dwarfism; E

2014
Drug-refractory aggression, self-injurious behavior, and severe tantrums in autism spectrum disorders: a chart review study.
    Autism : the international journal of research and practice, 2015, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aggression; Antipsychotic Agents; Aripiprazole; Autistic Disorder; Child; Child D

2015
Risperidone-associated urinary incontinence in patients with autistic disorder with mental retardation.
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:5

    Topics: Adult; Aged; Antipsychotic Agents; Autistic Disorder; Fecal Incontinence; Female; Humans; Intellectu

2014
Motor Weakness Related to Risperidone.
    Journal of child and adolescent psychopharmacology, 2015, Volume: 25, Issue:6

    Topics: Antipsychotic Agents; Child Behavior Disorders; Child, Preschool; Humans; Intellectual Disability; M

2015
Effectiveness of long-acting risperidone in a patient with comorbid intellectual disability, catatonic schizophrenia, and oneiroid syndrome.
    International journal of psychiatry in medicine, 2015, Volume: 50, Issue:3

    Topics: Adult; Ambroxol; Antipsychotic Agents; Brain; Dreams; Follow-Up Studies; Humans; Intellectual Disabi

2015
[Case report: Neuroleptic malignant syndrome and diagnostic difficulties].
    L'Encephale, 2016, Volume: 42, Issue:3

    Topics: Antipsychotic Agents; Dantrolene; Female; Humans; Intellectual Disability; Middle Aged; Muscle Relax

2016
Effectiveness of switching from oral ziprasidone to risperidone in a patient with comorbid autistic disorder, profound intellectual disability, Gilbert syndrome, and exacerbation of psychosis.
    Psychiatria Danubina, 2016, Volume: 28, Issue:1

    Topics: Adult; Antipsychotic Agents; Autistic Disorder; Comorbidity; Gilbert Disease; Humans; Intellectual D

2016
Mild Hypothermia in a Child with Low-Dose Risperidone.
    Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie, 2017, Volume: 45, Issue:4

    Topics: Aggression; Attention Deficit Disorder with Hyperactivity; Child; Cognitive Behavioral Therapy; Comb

2017
Beware of over-interpreting negative trials.
    Journal of autism and developmental disorders, 2008, Volume: 38, Issue:9

    Topics: Adult; Antipsychotic Agents; Awareness; Clinical Trials as Topic; Humans; Intellectual Disability; P

2008
Dose-dependent effect of risperidone treatment in a case of 22q13.3 deletion syndrome.
    Brain & development, 2010, Volume: 32, Issue:5

    Topics: Abnormalities, Multiple; Adolescent; Aggression; Animals; Antipsychotic Agents; Chromosome Deletion;

2010
Examining risperidone use in those diagnosed with autism 1 year after FDA approval.
    The Journal of clinical psychiatry, 2010, Volume: 71, Issue:5

    Topics: Adolescent; Adult; Age of Onset; Antipsychotic Agents; Autistic Disorder; Child; Humans; Intellectua

2010
Minimum effective and relapse-associated doses of risperidone and olanzapine in aggressive, intellectually disabled adults.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:2

    Topics: Adult; Age Factors; Aggression; Benzodiazepines; Dose-Response Relationship, Drug; Female; Humans; I

2011
Novel clinical finding in MECP2 duplication syndrome.
    European child & adolescent psychiatry, 2011, Volume: 20, Issue:7

    Topics: Child; Child Development; Chromosomes, Human, X; Cognitive Behavioral Therapy; Early Intervention, E

2011
Diphenhydramine use in the treatment of risperidone-induced sialorrhea.
    Journal of child and adolescent psychopharmacology, 2012, Volume: 22, Issue:3

    Topics: Adolescent; Antipsychotic Agents; Diphenhydramine; Dose-Response Relationship, Drug; Follow-Up Studi

2012
GABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction.
    Translational psychiatry, 2012, Jul-17, Volume: 2

    Topics: Animals; Autistic Disorder; Baclofen; Disease Models, Animal; Evoked Potentials, Auditory; Explorato

2012
Antecollis, lingual dystonia, and mutism secondary to risperidone.
    The Journal of neuropsychiatry and clinical neurosciences, 2012,Summer, Volume: 24, Issue:3

    Topics: Antipsychotic Agents; Child; Dystonia; Female; Humans; Intellectual Disability; Mutism; Risperidone;

2012
Effectiveness of naltrexone for treating pathologic skin picking behavior in an adolescent with Prader-Willi syndrome.
    Journal of child and adolescent psychopharmacology, 2012, Volume: 22, Issue:5

    Topics: Adolescent; Antipsychotic Agents; Behavior Therapy; Compulsive Behavior; Humans; Intellectual Disabi

2012
Reader response to, "Effects of risperidone on aberrant behavior in persons with developmental disabilities: I. A double-blind crossover study using multiple measures".
    American journal of mental retardation : AJMR, 2003, Volume: 108, Issue:3

    Topics: Antipsychotic Agents; Cross-Over Studies; Double-Blind Method; Humans; Intellectual Disability; Ment

2003
Risperidone-induced obsessive-compulsive symptoms in two children.
    Journal of child and adolescent psychopharmacology, 2003, Volume: 13 Suppl 1

    Topics: Adult; Aggression; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Female; Huma

2003
Neuroleptic malignant syndrome in juvenile neuronal ceroid lipofuscinosis associated with low-dose risperidone therapy.
    Journal of inherited metabolic disease, 2003, Volume: 26, Issue:6

    Topics: Adult; Antipsychotic Agents; Creatine Kinase; Dopamine; Female; Fever; Hallucinations; Humans; Intel

2003
[Experience with Risperidone in the treatment of institutionalized mentally retarded patients, with special reference to treatment of aggressive states].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Aggression; Antipsychotic Agents; Dopamine Antagonists; Female; Humans; Hungary; Instit

2004
Metabolic effects associated with atypical antipsychotic treatment in the developmentally disabled.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:9

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Body Mass Index; Cholesterol; Comorbidi

2005
Risperidone for the treatment of fecal smearing in a developmentally disabled adult.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2007, Feb-15, Volume: 64, Issue:4

    Topics: Adult; Antipsychotic Agents; Behavior Control; Disabled Persons; Feces; Hepatitis B; Humans; Intelle

2007
Risperidone-induced enuresis in two children with autistic disorder.
    Journal of child and adolescent psychopharmacology, 2007, Volume: 17, Issue:4

    Topics: Antipsychotic Agents; Autistic Disorder; Benzodiazepines; Child; Diurnal Enuresis; Humans; Intellect

2007
Efficacy of risperidone treatment in Smith-Magenis syndrome (del 17 pll. 2).
    Psychiatria Danubina, 2007, Volume: 19, Issue:3

    Topics: Abnormalities, Multiple; Adolescent; Aggression; Antipsychotic Agents; Attention Deficit Disorder wi

2007
Temporary increases in problem behavior and sleep disruption following decreases in medication: a descriptive analysis of conditional rates.
    Behavior modification, 2007, Volume: 31, Issue:6

    Topics: Adolescent; Aggression; Antipsychotic Agents; Child; Dose-Response Relationship, Drug; Female; Human

2007
Atypical antipsychotic medication improves aggression, but not self-injurious behaviour, in adults with intellectual disabilities.
    Journal of intellectual disability research : JIDR, 2008, Volume: 52, Issue:Pt 2

    Topics: Adult; Aggression; Antipsychotic Agents; Benzodiazepines; Body Weight; Dibenzothiazepines; Dose-Resp

2008
Risperidone-induced double incontinence.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, May-15, Volume: 32, Issue:4

    Topics: Adolescent; Antipsychotic Agents; Autistic Disorder; Child; Fecal Incontinence; Female; Humans; Inte

2008
Antipsychotics in individuals with intellectual disability.
    Lancet (London, England), 2008, May-03, Volume: 371, Issue:9623

    Topics: Antipsychotic Agents; Behavior Control; Haloperidol; Humans; Intellectual Disability; Randomized Con

2008
Risperidone in the treatment of pervasive developmental disorder.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1994, Volume: 39, Issue:7

    Topics: Adolescent; Adult; Antipsychotic Agents; Autistic Disorder; Child; Child Development Disorders, Perv

1994
Neuroleptic malignant syndrome with risperidone.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:2

    Topics: Adult; Antipsychotic Agents; Dose-Response Relationship, Drug; Humans; Intellectual Disability; Male

1996
Substituting traditional antipsychotics with risperidone for individuals with mental retardation.
    Mental retardation, 1996, Volume: 34, Issue:6

    Topics: Adult; Aged; Antipsychotic Agents; Comorbidity; Dose-Response Relationship, Drug; Dyskinesia, Drug-I

1996
Risperidone and explosive aggressive autism.
    Journal of autism and developmental disorders, 1997, Volume: 27, Issue:3

    Topics: Activities of Daily Living; Adolescent; Adult; Aggression; Antipsychotic Agents; Autistic Disorder;

1997
Risperidone in young children with pervasive developmental disorders and other developmental disabilities.
    Journal of child and adolescent psychopharmacology, 1996,Spring, Volume: 6, Issue:1

    Topics: Aggression; Autistic Disorder; Child; Child Development Disorders, Pervasive; Child, Preschool; Huma

1996
Brief report: risperidone for severely disturbed behavior and tardive dyskinesia in developmentally disabled adults.
    Journal of autism and developmental disorders, 1997, Volume: 27, Issue:4

    Topics: Adult; Aggression; Antipsychotic Agents; Comorbidity; Dose-Response Relationship, Drug; Drug Adminis

1997
Risperidone in children and adolescents with pervasive developmental disorder: pilot trial and follow-up.
    Journal of child and adolescent psychopharmacology, 1997, Volume: 7, Issue:3

    Topics: Adolescent; Anger; Child; Child Development Disorders, Pervasive; Dopamine Antagonists; Female; Huma

1997
Risperidone for aggression and self-injurious behavior in adults with mental retardation.
    Journal of autism and developmental disorders, 1998, Volume: 28, Issue:3

    Topics: Adult; Aggression; Antipsychotic Agents; Behavior Therapy; Combined Modality Therapy; Female; Humans

1998
Brief report: two-year control of behavioral symptoms with risperidone in two profoundly retarded adults with autism.
    Journal of autism and developmental disorders, 1999, Volume: 29, Issue:1

    Topics: Adult; Autistic Disorder; Compulsive Behavior; Dopamine Antagonists; Female; Gynecomastia; Humans; I

1999
Use of the atypical antipsychotics Olanzapine and Risperidone in adults with intellectual disability.
    Journal of intellectual disability research : JIDR, 2000, Volume: 44 ( Pt 2)

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Female; Follow-Up St

2000
Weight gain with risperidone among patients with mental retardation: effect of calorie restriction.
    The Journal of clinical psychiatry, 2001, Volume: 62, Issue:2

    Topics: Aggression; Antipsychotic Agents; Diet; Dose-Response Relationship, Drug; Energy Intake; Humans; Int

2001
Brief report: effects of clozapine on self-injurious behavior of two risperidone nonresponders with mental retardation.
    Journal of autism and developmental disorders, 2001, Volume: 31, Issue:1

    Topics: Adult; Clozapine; Dose-Response Relationship, Drug; Humans; Intellectual Disability; Male; Middle Ag

2001
Risperidone for controlling aggressive behavior in a mentally retarded child: a case report.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2001, Volume: 84, Issue:6

    Topics: Aggression; Antipsychotic Agents; Child; Humans; Intellectual Disability; Male; Risperidone

2001
Atypical antipsychotic use in treating adolescents and young adults with developmental disabilities.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2001, Volume: 46, Issue:8

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Intellectual Disability; M

2001
Risperidone-induced Pisa syndrome.
    The Australian and New Zealand journal of psychiatry, 2002, Volume: 36, Issue:1

    Topics: Adult; Antipsychotic Agents; Dystonic Disorders; Female; Humans; Intellectual Disability; Posture; P

2002
[Possibilities and limits of treatment of aggressive behavior in patients with mental retardation with risperidone].
    Der Nervenarzt, 2002, Volume: 73, Issue:3

    Topics: Adult; Aggression; Antipsychotic Agents; Female; Follow-Up Studies; Humans; Intellectual Disability;

2002