risperidone has been researched along with Huntington Disease in 15 studies
Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Risperidone was an effective treatment in this case." | 5.62 | Bilateral chorea following severe traumatic brain injury treated with risperidone. ( Koffer, J; Krasna, D; Montgomery, E; Segal, M, 2021) |
| "Risperidone has been shown in several trials to have a statistically significant benefit when used in a therapeutic context." | 3.01 | Neuropharmacological effect of risperidone: From chemistry to medicine. ( Afzal, O; Al-Abbasi, FA; Alfawaz Altamimi, AS; Almalki, WH; Alzarea, SI; Bhat, AA; Dua, K; Gupta, G; Kazmi, I; Singh, SK, 2023) |
| "Risperidone was an effective treatment in this case." | 1.62 | Bilateral chorea following severe traumatic brain injury treated with risperidone. ( Koffer, J; Krasna, D; Montgomery, E; Segal, M, 2021) |
| "UHDRS (Unified Huntington's Disease Rating Scale) motor scores were obtained from medical records as an index of disease progression." | 1.42 | Examining Huntington's disease patient and informant concordance on frontally mediated behaviors. ( Cimino, CR; Hergert, DC; Sanchez-Ramos, J, 2015) |
| "We described a 32-year-old woman with Huntington's disease (HD) who presented with severe chorea, psychosis and cognitive abnormalities." | 1.33 | Clinical experience with risperidone and memantine in the treatment of Huntington's disease. ( Cakir, A; Cankurtaran, ES; Ozalp, E; Soygur, H, 2006) |
| "A positive family history of Huntington's disease and DNA analysis helped to establish the diagnosis." | 1.30 | Psychiatric and neuropsychological abnormalities in Huntington's disease: a case study. ( Brafman, I; Brenner, R; Madhusoodanan, S; Moise, D; Sindagi, J, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bhat, AA | 2 |
| Gupta, G | 2 |
| Afzal, O | 2 |
| Kazmi, I | 2 |
| Al-Abbasi, FA | 2 |
| Alfawaz Altamimi, AS | 2 |
| Almalki, WH | 2 |
| Alzarea, SI | 2 |
| Singh, SK | 2 |
| Dua, K | 2 |
| Krasna, D | 1 |
| Montgomery, E | 1 |
| Koffer, J | 1 |
| Segal, M | 1 |
| Ding, J | 1 |
| Gadit, AM | 1 |
| Hergert, DC | 1 |
| Sanchez-Ramos, J | 1 |
| Cimino, CR | 1 |
| Kao, YH | 1 |
| Chern, Y | 1 |
| Yang, HT | 1 |
| Chen, HM | 1 |
| Lin, CJ | 1 |
| Coppen, EM | 1 |
| Roos, RA | 1 |
| Johnston, TG | 1 |
| Cankurtaran, ES | 1 |
| Ozalp, E | 1 |
| Soygur, H | 1 |
| Cakir, A | 1 |
| Chou, KL | 1 |
| Borek, LL | 1 |
| Friedman, JH | 1 |
| Soliman, S | 1 |
| Haque, S | 1 |
| George, E | 1 |
| Madhusoodanan, S | 2 |
| Brenner, R | 2 |
| Moise, D | 1 |
| Sindagi, J | 1 |
| Brafman, I | 1 |
| Dallocchio, C | 1 |
| Buffa, C | 1 |
| Tinelli, C | 1 |
| Mazzarello, P | 1 |
| Parsa, MA | 1 |
| Szigethy, E | 1 |
| Voci, JM | 1 |
| Meltzer, HY | 1 |
| Erdemoglu, AK | 1 |
| Boratav, C | 1 |
3 reviews available for risperidone and Huntington Disease
| Article | Year |
|---|---|
Neuropharmacological effect of risperidone: From chemistry to medicine.
Topics: Antipsychotic Agents; Humans; Huntington Disease; Psychotic Disorders; Risperidone; Schizophrenia | 2023 |
Neuropharmacological effect of risperidone: From chemistry to medicine.
Topics: Antipsychotic Agents; Humans; Huntington Disease; Psychotic Disorders; Risperidone; Schizophrenia | 2023 |
Neuropharmacological effect of risperidone: From chemistry to medicine.
Topics: Antipsychotic Agents; Humans; Huntington Disease; Psychotic Disorders; Risperidone; Schizophrenia | 2023 |
Neuropharmacological effect of risperidone: From chemistry to medicine.
Topics: Antipsychotic Agents; Humans; Huntington Disease; Psychotic Disorders; Risperidone; Schizophrenia | 2023 |
Current Pharmacological Approaches to Reduce Chorea in Huntington's Disease.
Topics: Antipsychotic Agents; Benzodiazepines; Humans; Huntington Disease; Olanzapine; Risperidone; Tetraben | 2017 |
The management of psychosis in movement disorder patients.
Topics: Antipsychotic Agents; Clozapine; Haloperidol; Humans; Huntington Disease; Lewy Body Disease; Parkins | 2007 |
1 trial available for risperidone and Huntington Disease
| Article | Year |
|---|---|
Effectiveness of risperidone in Huntington chorea patients.
Topics: Antipsychotic Agents; Female; Humans; Huntington Disease; Male; Middle Aged; Risperidone; Treatment | 1999 |
11 other studies available for risperidone and Huntington Disease
| Article | Year |
|---|---|
Bilateral chorea following severe traumatic brain injury treated with risperidone.
Topics: Activities of Daily Living; Brain Injuries, Traumatic; Chorea; Humans; Huntington Disease; Male; Ris | 2021 |
Psychosis with Huntington's disease: role of antipsychotic medications.
Topics: Aggression; Antipsychotic Agents; Humans; Huntington Disease; Male; Middle Aged; Psychotic Disorders | 2014 |
Examining Huntington's disease patient and informant concordance on frontally mediated behaviors.
Topics: Adult; Aged; Antipsychotic Agents; Awareness; Cognition Disorders; Disease Progression; Female; Fron | 2015 |
Regulation of P-glycoprotein expression in brain capillaries in Huntington's disease and its impact on brain availability of antipsychotic agents risperidone and paliperidone.
Topics: Animals; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological A | 2016 |
Risperidone long-acting injection and Huntington's disease: case series with significant psychiatric and behavioural symptoms.
Topics: Adolescent; Adult; Antipsychotic Agents; Behavioral Symptoms; Cognition; Delayed-Action Preparations | 2011 |
Clinical experience with risperidone and memantine in the treatment of Huntington's disease.
Topics: Adult; Cognition; Dopamine Antagonists; Drug Therapy, Combination; Excitatory Amino Acid Antagonists | 2006 |
Stalking and Huntington's disease: a neurobiological link?
Topics: Aggression; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Female; Fluvoxamine; For | 2007 |
Psychiatric and neuropsychological abnormalities in Huntington's disease: a case study.
Topics: Antipsychotic Agents; Cognition Disorders; Female; Humans; Huntington Disease; Middle Aged; Psychoti | 1998 |
Use of risperidone in psychosis associated with Huntington's disease.
Topics: Antipsychotic Agents; Female; Humans; Huntington Disease; Middle Aged; Psychotic Disorders; Risperid | 1998 |
Risperidone in treatment of choreoathetosis of Huntington's disease.
Topics: Clozapine; Dopamine Antagonists; Female; Humans; Huntington Disease; Middle Aged; Risperidone; Serot | 1997 |
Risperidone in chorea and psychosis of Huntington's disease.
Topics: Adult; Antipsychotic Agents; Female; Humans; Huntington Disease; Psychotic Disorders; Risperidone | 2002 |