Page last updated: 2024-11-03

risperidone and Gynecomastia

risperidone has been researched along with Gynecomastia in 19 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Gynecomastia: Enlargement of the BREAST in the males, caused by an excess of ESTROGENS. Physiological gynecomastia is normally observed in NEWBORNS; ADOLESCENT; and AGING males.

Research Excerpts

ExcerptRelevanceReference
"This open-label, prospective, 4-month study in hyperprolactinemic patients with schizophrenia explored whether prolactin levels decrease after switching antipsychotic therapy to olanzapine."9.12Improvement in hyperprolactinemia and reproductive comorbidities in patients with schizophrenia switched from conventional antipsychotics or risperidone to olanzapine. ( Ahl, J; Kinon, BJ; Liu-Seifert, H; Maguire, GA, 2006)
"The purpose of this study was to quantify the risk of gynecomastia with risperidone in adolescent and young adult males."7.81Risperidone and Risk of Gynecomastia in Young Men. ( Brophy, JM; Carleton, B; Etminan, M, 2015)
"Hyperprolactinemia is a common side effect in young males treated over the long term with risperidone."7.78Risk of hyperprolactinemia and sexual side effects in males 10-20 years old diagnosed with autism spectrum disorders or disruptive behavior disorder and treated with risperidone. ( Boot, AM; Buitelaar, JK; Roke, Y; Tenback, D; van Harten, PN, 2012)
"Risperidone is associated with hyperprolactinemia and its consequent symptoms such as gynecomastia, galactorrhea and sexual dysfunction in adults, and less so in adolescents."7.77Euprolactinemic gynecomastia and galactorrhea with risperidone-fluvoxamine combination. ( Praharaj, SK; Pratheesh, PJ; Srivastava, A, 2011)
"Studies performed in adult patients unambiguously demonstrate a marked effect of risperidone on prolactin blood levels, with possible clinical effects related to hyperprolactinemia, such as gynecomastia and galactorrhea."7.73Risperidone-induced symptomatic hyperprolactinaemia in adolescents. ( Eap, CB; Holzer, L, 2006)
"This open-label, prospective, 4-month study in hyperprolactinemic patients with schizophrenia explored whether prolactin levels decrease after switching antipsychotic therapy to olanzapine."5.12Improvement in hyperprolactinemia and reproductive comorbidities in patients with schizophrenia switched from conventional antipsychotics or risperidone to olanzapine. ( Ahl, J; Kinon, BJ; Liu-Seifert, H; Maguire, GA, 2006)
"The purpose of this study was to quantify the risk of gynecomastia with risperidone in adolescent and young adult males."3.81Risperidone and Risk of Gynecomastia in Young Men. ( Brophy, JM; Carleton, B; Etminan, M, 2015)
"Hyperprolactinemia is a common side effect in young males treated over the long term with risperidone."3.78Risk of hyperprolactinemia and sexual side effects in males 10-20 years old diagnosed with autism spectrum disorders or disruptive behavior disorder and treated with risperidone. ( Boot, AM; Buitelaar, JK; Roke, Y; Tenback, D; van Harten, PN, 2012)
"Risperidone is associated with hyperprolactinemia and its consequent symptoms such as gynecomastia, galactorrhea and sexual dysfunction in adults, and less so in adolescents."3.77Euprolactinemic gynecomastia and galactorrhea with risperidone-fluvoxamine combination. ( Praharaj, SK; Pratheesh, PJ; Srivastava, A, 2011)
"Studies performed in adult patients unambiguously demonstrate a marked effect of risperidone on prolactin blood levels, with possible clinical effects related to hyperprolactinemia, such as gynecomastia and galactorrhea."3.73Risperidone-induced symptomatic hyperprolactinaemia in adolescents. ( Eap, CB; Holzer, L, 2006)
" Risperidone had the highest adjusted reporting ratios for hyperprolactinemia (EBGM 34."3.73Atypical antipsychotics and pituitary tumors: a pharmacovigilance study. ( Doraiswamy, PM; Levine, JG; Szarfman, A; Tonning, JM, 2006)
"To review the evidence concerning treatment-related gynecomastia in patients taking spironolactone, antiandrogens, 5 alpha-reductase inhibitors, lipid-lowering and psychotropic drugs."2.72Drug-induced gynecomastia: A systematic review and meta-analysis of randomized clinical trials. ( Magri, V; Montanari, E; Perletti, G; Stamatiou, K; Trinchieri, A; Trinchieri, M, 2021)
" In addition, adverse events were also evaluated."1.34[A naturalistic, observational study of outpatients with schizophrenia: efficacy and safety results after 6 months. The International Schizophrenia Outpatient Health Outcomes study, IC-SOHO]. ( Agoston, T; István, S; Tamás, T; Zoltán, J, 2007)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (15.79)18.2507
2000's7 (36.84)29.6817
2010's8 (42.11)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Trinchieri, A1
Perletti, G1
Magri, V1
Stamatiou, K1
Trinchieri, M1
Montanari, E1
Eugene, AR2
Eugene, B2
Etminan, M2
Heran, B1
Carleton, B2
Brophy, JM2
Koplewicz, HS1
Findling, RL1
Daneman, D1
Dyer, O1
Emsley, R1
Oosthuizen, P1
Koen, L1
Niehaus, DJ1
Medori, R1
Rabinowitz, J1
Pratheesh, PJ1
Praharaj, SK1
Srivastava, A1
Roke, Y1
Buitelaar, JK1
Boot, AM1
Tenback, D1
van Harten, PN1
Lambert, M1
Haro, JM1
Novick, D1
Edgell, ET1
Kennedy, L1
Ratcliffe, M1
Naber, D1
Mendhekar, DN1
Andrade, CR1
Kinon, BJ1
Ahl, J1
Liu-Seifert, H1
Maguire, GA1
Holzer, L1
Eap, CB1
Szarfman, A1
Tonning, JM1
Levine, JG1
Doraiswamy, PM1
István, S1
Agoston, T1
Tamás, T1
Zoltán, J1
Shiwach, RS1
Carmody, TJ1
Benazzi, F1
Dartnall, NA1
Holmes, JP1
Morgan, SN1
McDougle, CJ1

Reviews

1 review available for risperidone and Gynecomastia

ArticleYear
Drug-induced gynecomastia: A systematic review and meta-analysis of randomized clinical trials.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2021, Dec-21, Volume: 93, Issue:4

    Topics: Antipsychotic Agents; Gynecomastia; Humans; Male; Pharmaceutical Preparations; Randomized Controlled

2021

Trials

1 trial available for risperidone and Gynecomastia

ArticleYear
Improvement in hyperprolactinemia and reproductive comorbidities in patients with schizophrenia switched from conventional antipsychotics or risperidone to olanzapine.
    Psychoneuroendocrinology, 2006, Volume: 31, Issue:5

    Topics: Antipsychotic Agents; Benzodiazepines; Body Weight; Estradiol; Female; Galactorrhea; Gynecomastia; H

2006

Other Studies

17 other studies available for risperidone and Gynecomastia

ArticleYear
An opportunity for clinical pharmacology trained physicians to improve patient drug safety: A retrospective analysis of adverse drug reactions in teenagers.
    F1000Research, 2018, Volume: 7

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Biomarkers; Child; Child, Preschool; Databases,

2018
An opportunity for clinical pharmacology trained physicians to improve patient drug safety: A retrospective analysis of adverse drug reactions in teenagers.
    F1000Research, 2018, Volume: 7

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Biomarkers; Child; Child, Preschool; Databases,

2018
An opportunity for clinical pharmacology trained physicians to improve patient drug safety: A retrospective analysis of adverse drug reactions in teenagers.
    F1000Research, 2018, Volume: 7

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Biomarkers; Child; Child, Preschool; Databases,

2018
An opportunity for clinical pharmacology trained physicians to improve patient drug safety: A retrospective analysis of adverse drug reactions in teenagers.
    F1000Research, 2018, Volume: 7

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Biomarkers; Child; Child, Preschool; Databases,

2018
Risperidone use and risk for gynecomastia in men.
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Case-Control Studies; Databases, Factual; Gyne

2014
Risperidone and Risk of Gynecomastia in Young Men.
    Journal of child and adolescent psychopharmacology, 2015, Volume: 25, Issue:9

    Topics: Adolescent; Adult; Antipsychotic Agents; Case-Control Studies; Gynecomastia; Humans; Male; Risk; Ris

2015
From the Editor-in-Chief's Desk.
    Journal of child and adolescent psychopharmacology, 2015, Volume: 25, Issue:9

    Topics: Bipolar Disorder; Depression; Gynecomastia; Humans; Mental Processes; Quetiapine Fumarate; Reward; R

2015
Prolactin Levels During Long-Term Risperidone Treatment in Children and Adolescents: a reanalysis of data.
    The Journal of clinical psychiatry, 2016, Volume: 77, Issue:2

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Data I

2016
Johnson & Johnson is ordered to pay $70m to boy who developed gynecomastia.
    BMJ (Clinical research ed.), 2016, Jul-11, Volume: 354

    Topics: Antipsychotic Agents; Compensation and Redress; Drug Labeling; Gynecomastia; Humans; Legislation, Dr

2016
Oral versus injectable antipsychotic treatment in early psychosis: post hoc comparison of two studies.
    Clinical therapeutics, 2008, Volume: 30, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Antipsychotic Agents; Delayed-Action Preparations; Double-B

2008
Euprolactinemic gynecomastia and galactorrhea with risperidone-fluvoxamine combination.
    Psychopharmacology bulletin, 2011, Volume: 44, Issue:1

    Topics: Drug Therapy, Combination; Fluvoxamine; Galactorrhea; Gynecomastia; Humans; Male; Obsessive-Compulsi

2011
Risk of hyperprolactinemia and sexual side effects in males 10-20 years old diagnosed with autism spectrum disorders or disruptive behavior disorder and treated with risperidone.
    Journal of child and adolescent psychopharmacology, 2012, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child;

2012
Olanzapine vs. other antipsychotics in actual out-patient settings: six months tolerability results from the European Schizophrenia Out-patient Health Outcomes study.
    Acta psychiatrica Scandinavica, 2005, Volume: 111, Issue:3

    Topics: Adult; Ambulatory Care; Amenorrhea; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Clozapin

2005
Unilateral gynecomastia induced by risperidone in a geriatric male patient.
    Indian journal of medical sciences, 2005, Volume: 59, Issue:8

    Topics: Aged; Antipsychotic Agents; Gynecomastia; Humans; Male; Risperidone

2005
Risperidone-induced symptomatic hyperprolactinaemia in adolescents.
    Journal of clinical psychopharmacology, 2006, Volume: 26, Issue:2

    Topics: Adolescent; Antipsychotic Agents; Drug Monitoring; Female; Galactorrhea; Gynecomastia; Humans; Hyper

2006
Atypical antipsychotics and pituitary tumors: a pharmacovigilance study.
    Pharmacotherapy, 2006, Volume: 26, Issue:6

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Amenorrhea; Antipsychotic Agents; Aripiprazole;

2006
[A naturalistic, observational study of outpatients with schizophrenia: efficacy and safety results after 6 months. The International Schizophrenia Outpatient Health Outcomes study, IC-SOHO].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2007, Volume: 9, Issue:3

    Topics: Adult; Aggression; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Dibenzo

2007
Prolactogenic effects of risperidone in male patients--a preliminary study.
    Acta psychiatrica Scandinavica, 1998, Volume: 98, Issue:1

    Topics: Antipsychotic Agents; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedul

1998
Gynecomastia with risperidone-fluoxetine combination.
    Pharmacopsychiatry, 1999, Volume: 32, Issue:1

    Topics: Adult; Antipsychotic Agents; Drug Combinations; Fluoxetine; Gynecomastia; Humans; Male; Psychiatric

1999
Brief report: two-year control of behavioral symptoms with risperidone in two profoundly retarded adults with autism.
    Journal of autism and developmental disorders, 1999, Volume: 29, Issue:1

    Topics: Adult; Autistic Disorder; Compulsive Behavior; Dopamine Antagonists; Female; Gynecomastia; Humans; I

1999