risperidone has been researched along with Glucose Intolerance in 4 studies
Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.
Glucose Intolerance: A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In conclusion, long-term administration of risperidone may exacerbate diabetes syndrome, nonalcoholic fatty liver disease, and kidney injury." | 5.62 | Risperidone Exacerbates Glucose Intolerance, Nonalcoholic Fatty Liver Disease, and Renal Impairment in Obese Mice. ( Chang, CC; Chang, GR; Chou, LS; Hou, PH; Hsiao, LW; Liao, HJ; Lin, TC; Mao, FC; Tsai, HP; Wu, CF; Yang, WC, 2021) |
| " After 4-week administration, clozapine (10mg/kg/d) and risperidone (1mg/kg/d) both caused glucose intolerance and insulin resistance in VD deficient rats, but not in rats with sufficient VD status." | 3.81 | Vitamin D deficiency exacerbates atypical antipsychotic-induced metabolic side effects in rats: involvement of the INSIG/SREBP pathway. ( Cai, H; Dang, R; Guo, R; He, X; Jiang, P; Li, H; Liu, Y; Wu, Y; Xu, P; Zhang, L; Zhu, W, 2015) |
| "In subproject Ι, 45 patients receiving the 2nd generation antipsychotics risperidone, clozapine or olanzapine were compared regarding prolactin (PRL), body mass index (BMI), insulin, homeostasis model assessment of insulin resistance (HOMA-IR) and blood lipids." | 3.77 | Effect of antipsychotic-induced hyperprolactinemia on anthropometric measures, insulin sensitivity and lipid profile in patients with schizophrenia or related psychoses. ( Berinder, K; Hulting, AL; Melkersson, K, 2011) |
| "To examine quantitatively the association between glucose intolerance including diabetes mellitus and the use of the atypical antipsychotics clozapine, olanzapine or risperidone, and to identify possible risk factors for the development of glucose intolerance during treatment with these drugs." | 3.71 | Glucose intolerance with atypical antipsychotics. ( Hägg, S; Hedenmalm, K; Mortimer, O; Spigset, O; Ståhl, M, 2002) |
| " In conclusion, long-term administration of risperidone may exacerbate diabetes syndrome, nonalcoholic fatty liver disease, and kidney injury." | 1.62 | Risperidone Exacerbates Glucose Intolerance, Nonalcoholic Fatty Liver Disease, and Renal Impairment in Obese Mice. ( Chang, CC; Chang, GR; Chou, LS; Hou, PH; Hsiao, LW; Liao, HJ; Lin, TC; Mao, FC; Tsai, HP; Wu, CF; Yang, WC, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsai, HP | 1 |
| Hou, PH | 1 |
| Mao, FC | 1 |
| Chang, CC | 1 |
| Yang, WC | 1 |
| Wu, CF | 1 |
| Liao, HJ | 1 |
| Lin, TC | 1 |
| Chou, LS | 1 |
| Hsiao, LW | 1 |
| Chang, GR | 1 |
| Dang, R | 1 |
| Jiang, P | 1 |
| Cai, H | 1 |
| Li, H | 1 |
| Guo, R | 1 |
| Wu, Y | 1 |
| Zhang, L | 1 |
| Zhu, W | 1 |
| He, X | 1 |
| Liu, Y | 1 |
| Xu, P | 1 |
| Melkersson, K | 1 |
| Berinder, K | 1 |
| Hulting, AL | 1 |
| Hedenmalm, K | 1 |
| Hägg, S | 1 |
| Ståhl, M | 1 |
| Mortimer, O | 1 |
| Spigset, O | 1 |
4 other studies available for risperidone and Glucose Intolerance
| Article | Year |
|---|---|
Risperidone Exacerbates Glucose Intolerance, Nonalcoholic Fatty Liver Disease, and Renal Impairment in Obese Mice.
Topics: Adipocytes; Adiponectin; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Ca | 2021 |
Vitamin D deficiency exacerbates atypical antipsychotic-induced metabolic side effects in rats: involvement of the INSIG/SREBP pathway.
Topics: Animals; Antipsychotic Agents; Body Weight; Clozapine; Disease Models, Animal; Eating; Glucose Intol | 2015 |
Effect of antipsychotic-induced hyperprolactinemia on anthropometric measures, insulin sensitivity and lipid profile in patients with schizophrenia or related psychoses.
Topics: Adult; Anthropometry; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Clozapine; Female; Gluco | 2011 |
Glucose intolerance with atypical antipsychotics.
Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Chlor | 2002 |