Page last updated: 2024-11-03

risperidone and Glioma

risperidone has been researched along with Glioma in 7 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
" The present study examines the effects of antipsychotic drugs, haloperidol and risperidone, on the expression of HSP70 produced by MK-801 in rat C6 glioma cells."7.74Effects of haloperidol and risperidone on the expression of heat shock protein 70 in MK-801-treated rat C6 glioma cells. ( Chai, YG; Choi, J; Choi, MR; Kim, D; Kim, DJ; Kim, SH; Lee, JS; Park, YC; Roh, K; Roh, S; Yang, BH, 2008)
" We used two-dimensional gel electrophoresis coupled with MALDI-TOF/TOF mass spectrometry protein identification to analyze differentially expressed proteins in haloperidol-, risperidone-, and clozapine-treated C6 glioma cells."3.79Two-dimensional gel electrophoresis revealed antipsychotic drugs induced protein expression modulations in C6 glioma cells. ( Chen, ML, 2013)
" The present study examines the effects of antipsychotic drugs, haloperidol and risperidone, on the expression of HSP70 produced by MK-801 in rat C6 glioma cells."3.74Effects of haloperidol and risperidone on the expression of heat shock protein 70 in MK-801-treated rat C6 glioma cells. ( Chai, YG; Choi, J; Choi, MR; Kim, D; Kim, DJ; Kim, SH; Lee, JS; Park, YC; Roh, K; Roh, S; Yang, BH, 2008)
"Risperidone can activate the Akt-GSK3β signaling pathway in the U251 cells, and PI3K is a common regulatory site in Akt-GSK3β signaling and D2 receptor gene expression."1.40[Regulation of PI3K-Akt-GSK3β signaling pathway in U251 cells by risperidone]. ( Gu, X; Li, T; Liang, L; Ma, X; Wang, Y; Wei, J; Xiang, B, 2014)
"Alniditan is a new migraine-abortive agent."1.29Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin ( Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R, 1996)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leysen, JE1
Gommeren, W1
Heylen, L1
Luyten, WH1
Van de Weyer, I1
Vanhoenacker, P1
Haegeman, G1
Schotte, A1
Van Gompel, P1
Wouters, R1
Lesage, AS1
Liang, L1
Wang, Y1
Wei, J1
Gu, X1
Xiang, B1
Ma, X1
Li, T1
Roh, K1
Roh, S1
Yang, BH1
Lee, JS1
Chai, YG1
Choi, MR1
Park, YC1
Kim, DJ1
Kim, D1
Choi, J1
Kim, SH1
Chen, ML1
de Souza, DF1
Wartchow, K1
Hansen, F1
Lunardi, P1
Guerra, MC1
Nardin, P1
Gonçalves, CA1
Kagaya, A1
Motohashi, N1
Kugaya, A1
Yamaji, T1
Hayashi, T1
Okamoto, Y1
Shinno, H1
Takebayashi, M1
Uchitomi, Y1
Yamawaki, S1
Griffon, N1
Pilon, C1
Sautel, F1
Schwartz, JC1
Sokoloff, P1

Other Studies

7 other studies available for risperidone and Glioma

ArticleYear
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
    Molecular pharmacology, 1996, Volume: 50, Issue:6

    Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorde

1996
[Regulation of PI3K-Akt-GSK3β signaling pathway in U251 cells by risperidone].
    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2014, Volume: 31, Issue:6

    Topics: Antipsychotic Agents; Cell Line, Tumor; Glioma; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase

2014
Effects of haloperidol and risperidone on the expression of heat shock protein 70 in MK-801-treated rat C6 glioma cells.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Dec-12, Volume: 32, Issue:8

    Topics: Animals; Cell Line, Tumor; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagoni

2008
Two-dimensional gel electrophoresis revealed antipsychotic drugs induced protein expression modulations in C6 glioma cells.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Jan-10, Volume: 40

    Topics: Animals; Antipsychotic Agents; Cell Line, Tumor; Clozapine; Electrophoresis, Gel, Two-Dimensional; F

2013
Interleukin-6-induced S100B secretion is inhibited by haloperidol and risperidone.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Jun-03, Volume: 43

    Topics: Animals; Antipsychotic Agents; Cell Line, Tumor; Cytokines; Enzyme-Linked Immunosorbent Assay; Glial

2013
Cyclic GMP generation mediated by 5-HT-2 receptors via nitric oxide-dependent pathway and its effect on the desensitization of 5-HT-2 receptors in C6 glioma cells.
    Journal of neural transmission. General section, 1995, Volume: 100, Issue:1

    Topics: Animals; Arginine; Calcium; Chelating Agents; Cyclic GMP; Dopamine Antagonists; Edetic Acid; Egtazic

1995
Antipsychotics with inverse agonist activity at the dopamine D3 receptor.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:10

    Topics: Animals; Antipsychotic Agents; Calcium; CHO Cells; Clozapine; Colforsin; Cricetinae; Cyclic AMP; DNA

1996