risperidone has been researched along with Galactorrhea in 26 studies
Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.
Galactorrhea: Excessive or inappropriate LACTATION in females or males, and not necessarily related to PREGNANCY. Galactorrhea can occur either unilaterally or bilaterally, and be profuse or sparse. Its most common cause is HYPERPROLACTINEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This open-label, prospective, 4-month study in hyperprolactinemic patients with schizophrenia explored whether prolactin levels decrease after switching antipsychotic therapy to olanzapine." | 9.12 | Improvement in hyperprolactinemia and reproductive comorbidities in patients with schizophrenia switched from conventional antipsychotics or risperidone to olanzapine. ( Ahl, J; Kinon, BJ; Liu-Seifert, H; Maguire, GA, 2006) |
| "This study was conducted to prospectively examine the effect of switching from risperidone to olanzapine on female schizophrenia patients who experienced menstrual disturbances, galactorrhea, and/or sexual dysfunction." | 9.10 | Effects of olanzapine on prolactin levels of female patients with schizophrenia treated with risperidone. ( Bahk, WM; Chae, JH; Dickson, RA; Jun, TY; Kim, DJ; Kim, KS; Pae, CU, 2002) |
| "Risperidone is associated with hyperprolactinemia and its consequent symptoms such as gynecomastia, galactorrhea and sexual dysfunction in adults, and less so in adolescents." | 7.77 | Euprolactinemic gynecomastia and galactorrhea with risperidone-fluvoxamine combination. ( Praharaj, SK; Pratheesh, PJ; Srivastava, A, 2011) |
| "Risperidone, as all atypical antipsychotics, can cause hyperprolactinemia which can in turn lead to galactorrhea." | 7.76 | Galactorrhea - side effect of risperidone in combination with depakine chrono in a patient with bipolar disorder. ( Grahovac, T; Pavlović, E; Peitl, MV; Peitl, V, 2010) |
| "Studies performed in adult patients unambiguously demonstrate a marked effect of risperidone on prolactin blood levels, with possible clinical effects related to hyperprolactinemia, such as gynecomastia and galactorrhea." | 7.73 | Risperidone-induced symptomatic hyperprolactinaemia in adolescents. ( Eap, CB; Holzer, L, 2006) |
| "We report on the occurrence of galactorrhea and amenorrhea associated with prolactin elevation after 6 months of treatment with risperidone." | 7.71 | Risperidone induced galactorrhea: a case analysis. ( Hariharan, J; Mohsin, J, 2002) |
| "We report on the occurrence of galactorrhea associated with a prolactin elevation within weeks of treatment with risperidone." | 7.70 | Risperidone-induced galactorrhea associated with a prolactin elevation. ( Gupta, S; Popli, A; Rangwani, SR, 1998) |
| "Risperidone was switched to another antipsychotic." | 5.34 | Risperidone-induced polydipsia and polyphagia associated with galactorrhea, abdominal pain, and rapid weight gain in an adolescent Hispanic female. ( Afzal, KI; Briones, DF; DeVargas, C, 2007) |
| "This open-label, prospective, 4-month study in hyperprolactinemic patients with schizophrenia explored whether prolactin levels decrease after switching antipsychotic therapy to olanzapine." | 5.12 | Improvement in hyperprolactinemia and reproductive comorbidities in patients with schizophrenia switched from conventional antipsychotics or risperidone to olanzapine. ( Ahl, J; Kinon, BJ; Liu-Seifert, H; Maguire, GA, 2006) |
| "This study was conducted to prospectively examine the effect of switching from risperidone to olanzapine on female schizophrenia patients who experienced menstrual disturbances, galactorrhea, and/or sexual dysfunction." | 5.10 | Effects of olanzapine on prolactin levels of female patients with schizophrenia treated with risperidone. ( Bahk, WM; Chae, JH; Dickson, RA; Jun, TY; Kim, DJ; Kim, KS; Pae, CU, 2002) |
| " Peak prolactin levels/any hyperprolactinemia/triple-upper-limit-of-normal-prolactin level were highest with risperidone (median = 56." | 4.31 | Antipsychotic-Related Prolactin Levels and Sexual Dysfunction in Mentally Ill Youth: A 3-Month Cohort Study. ( Carlson, HE; Correll, CU; Kazimi, MM; Koch, MT, 2023) |
| "Risperidone is associated with hyperprolactinemia and its consequent symptoms such as gynecomastia, galactorrhea and sexual dysfunction in adults, and less so in adolescents." | 3.77 | Euprolactinemic gynecomastia and galactorrhea with risperidone-fluvoxamine combination. ( Praharaj, SK; Pratheesh, PJ; Srivastava, A, 2011) |
| "Risperidone, as all atypical antipsychotics, can cause hyperprolactinemia which can in turn lead to galactorrhea." | 3.76 | Galactorrhea - side effect of risperidone in combination with depakine chrono in a patient with bipolar disorder. ( Grahovac, T; Pavlović, E; Peitl, MV; Peitl, V, 2010) |
| "Studies performed in adult patients unambiguously demonstrate a marked effect of risperidone on prolactin blood levels, with possible clinical effects related to hyperprolactinemia, such as gynecomastia and galactorrhea." | 3.73 | Risperidone-induced symptomatic hyperprolactinaemia in adolescents. ( Eap, CB; Holzer, L, 2006) |
| " Risperidone had the highest adjusted reporting ratios for hyperprolactinemia (EBGM 34." | 3.73 | Atypical antipsychotics and pituitary tumors: a pharmacovigilance study. ( Doraiswamy, PM; Levine, JG; Szarfman, A; Tonning, JM, 2006) |
| "Risperidone induced galactorrhea and hyperprolactinemia have been reported but its role in the growth of prolactinoma is not yet conclusive, due to extreme rarity of such cases." | 3.72 | Effect of risperidone on prolactinoma--a case report. ( Jiloha, RC; Mendhekar, DN; Srivastava, PK, 2004) |
| "We report on the occurrence of galactorrhea and amenorrhea associated with prolactin elevation after 6 months of treatment with risperidone." | 3.71 | Risperidone induced galactorrhea: a case analysis. ( Hariharan, J; Mohsin, J, 2002) |
| "We report on the occurrence of galactorrhea associated with a prolactin elevation within weeks of treatment with risperidone." | 3.70 | Risperidone-induced galactorrhea associated with a prolactin elevation. ( Gupta, S; Popli, A; Rangwani, SR, 1998) |
| "Ziprasidone was superior to risperidone in decreasing the PANSS positive symptoms subscore and the CGI-S score, and in increasing the GAF-F score." | 2.75 | Effectiveness of second-generation antipsychotics: a naturalistic, randomized comparison of olanzapine, quetiapine, risperidone, and ziprasidone. ( Johnsen, E; Jørgensen, HA; Kroken, RA; Wentzel-Larsen, T, 2010) |
| "Weight gain was found to be lower in the elderly for antipsychotic drugs, in particular for olanzapine." | 1.39 | Age and adverse drug reactions from psychopharmacological treatment: data from the AMSP drug surveillance programme in Switzerland. ( Baumann, P; Greil, W; Grohmann, R; Häberle, A; Schuhmann, T, 2013) |
| "Risperidone was switched to another antipsychotic." | 1.34 | Risperidone-induced polydipsia and polyphagia associated with galactorrhea, abdominal pain, and rapid weight gain in an adolescent Hispanic female. ( Afzal, KI; Briones, DF; DeVargas, C, 2007) |
| " In addition, adverse events were also evaluated." | 1.34 | [A naturalistic, observational study of outpatients with schizophrenia: efficacy and safety results after 6 months. The International Schizophrenia Outpatient Health Outcomes study, IC-SOHO]. ( Agoston, T; István, S; Tamás, T; Zoltán, J, 2007) |
| "Risperidone-associated increase in serum prolactin levels was not significantly correlated to the emergence of possible prolactin-related side effects." | 1.30 | Prolactin levels and adverse events in patients treated with risperidone. ( Brecher, M; Davis, JM; de Coster, R; Kleinberg, DL; Van Baelen, B, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 15 (57.69) | 29.6817 |
| 2010's | 6 (23.08) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Koch, MT | 1 |
| Carlson, HE | 1 |
| Kazimi, MM | 1 |
| Correll, CU | 1 |
| Lenz, K | 1 |
| Perry-Rose, J | 1 |
| Shad, M | 1 |
| Greil, W | 1 |
| Häberle, A | 1 |
| Schuhmann, T | 1 |
| Grohmann, R | 1 |
| Baumann, P | 1 |
| Emsley, R | 1 |
| Oosthuizen, P | 1 |
| Koen, L | 1 |
| Niehaus, DJ | 1 |
| Medori, R | 1 |
| Rabinowitz, J | 1 |
| Peitl, MV | 1 |
| Peitl, V | 1 |
| Grahovac, T | 1 |
| Pavlović, E | 1 |
| Johnsen, E | 1 |
| Kroken, RA | 1 |
| Wentzel-Larsen, T | 1 |
| Jørgensen, HA | 1 |
| Pratheesh, PJ | 1 |
| Praharaj, SK | 1 |
| Srivastava, A | 1 |
| Howland, RH | 1 |
| Hariharan, J | 1 |
| Mohsin, J | 1 |
| Gupta, SC | 1 |
| Jagadheesan, K | 1 |
| Basu, S | 1 |
| Paul, SE | 1 |
| Ilett, KF | 1 |
| Hackett, LP | 1 |
| Kristensen, JH | 1 |
| Vaddadi, KS | 1 |
| Gardiner, SJ | 1 |
| Begg, EJ | 1 |
| Mendhekar, DN | 1 |
| Jiloha, RC | 1 |
| Srivastava, PK | 1 |
| Lambert, M | 1 |
| Haro, JM | 1 |
| Novick, D | 1 |
| Edgell, ET | 1 |
| Kennedy, L | 1 |
| Ratcliffe, M | 1 |
| Naber, D | 1 |
| Kinon, BJ | 1 |
| Ahl, J | 1 |
| Liu-Seifert, H | 1 |
| Maguire, GA | 1 |
| Holzer, L | 1 |
| Eap, CB | 1 |
| Szarfman, A | 1 |
| Tonning, JM | 1 |
| Levine, JG | 1 |
| Doraiswamy, PM | 1 |
| Afzal, KI | 1 |
| Briones, DF | 1 |
| DeVargas, C | 1 |
| István, S | 1 |
| Agoston, T | 1 |
| Tamás, T | 1 |
| Zoltán, J | 1 |
| Schreiber, S | 1 |
| Segman, RH | 1 |
| Popli, A | 1 |
| Gupta, S | 2 |
| Rangwani, SR | 1 |
| Canuso, CM | 1 |
| Hanau, M | 1 |
| Jhamb, KK | 1 |
| Green, AI | 1 |
| Kleinberg, DL | 1 |
| Davis, JM | 1 |
| de Coster, R | 1 |
| Van Baelen, B | 1 |
| Brecher, M | 1 |
| Mabini, R | 1 |
| Wergowske, G | 1 |
| Baker, FM | 1 |
| Wallmeroth, A | 1 |
| Staub, JJ | 1 |
| Frank, B | 1 |
| Madhusoodanan, S | 1 |
| Kim, KS | 1 |
| Pae, CU | 1 |
| Chae, JH | 1 |
| Bahk, WM | 1 |
| Jun, TY | 1 |
| Kim, DJ | 1 |
| Dickson, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use, Effects and Side-effects of Second-generation Antipsychotics in a Naturalistic Setting.[NCT00932529] | Phase 4 | 226 participants (Actual) | Interventional | 2003-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for risperidone and Galactorrhea
| Article | Year |
|---|---|
Effectiveness of second-generation antipsychotics: a naturalistic, randomized comparison of olanzapine, quetiapine, risperidone, and ziprasidone.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Drug Administration Schedule; Dysk | 2010 |
Improvement in hyperprolactinemia and reproductive comorbidities in patients with schizophrenia switched from conventional antipsychotics or risperidone to olanzapine.
Topics: Antipsychotic Agents; Benzodiazepines; Body Weight; Estradiol; Female; Galactorrhea; Gynecomastia; H | 2006 |
Effects of olanzapine on prolactin levels of female patients with schizophrenia treated with risperidone.
Topics: Adolescent; Adult; Amenorrhea; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Female | 2002 |
23 other studies available for risperidone and Galactorrhea
| Article | Year |
|---|---|
Antipsychotic-Related Prolactin Levels and Sexual Dysfunction in Mentally Ill Youth: A 3-Month Cohort Study.
Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Cohort Studies; Erectile Dysfunctio | 2023 |
Delayed galactorrhea after discontinuation of risperidone in a schizophrenia patient.
Topics: Adult; Antipsychotic Agents; Galactorrhea; Humans; Male; Risperidone; Schizophrenia; Time | 2017 |
Age and adverse drug reactions from psychopharmacological treatment: data from the AMSP drug surveillance programme in Switzerland.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; An | 2013 |
Oral versus injectable antipsychotic treatment in early psychosis: post hoc comparison of two studies.
Topics: Administration, Oral; Adolescent; Adult; Antipsychotic Agents; Delayed-Action Preparations; Double-B | 2008 |
Galactorrhea - side effect of risperidone in combination with depakine chrono in a patient with bipolar disorder.
Topics: Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Dose-Response Relationship, Drug; Drug Ther | 2010 |
Euprolactinemic gynecomastia and galactorrhea with risperidone-fluvoxamine combination.
Topics: Drug Therapy, Combination; Fluvoxamine; Galactorrhea; Gynecomastia; Humans; Male; Obsessive-Compulsi | 2011 |
The challenges of clinical psychopharmacological management.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Community Mental Health Services; Comorbidity; Coopera | 2012 |
Risperidone induced galactorrhea: a case analysis.
Topics: Adult; Antipsychotic Agents; Female; Galactorrhea; Humans; Risperidone; Schizophrenia | 2002 |
Risperidone-induced galactorrhoea: a case series.
Topics: Adult; Depressive Disorder, Major; Female; Galactorrhea; Humans; Risperidone; Selective Serotonin Re | 2003 |
Transfer of risperidone and 9-hydroxyrisperidone into human milk.
Topics: Adult; Area Under Curve; Breast Feeding; Depression, Postpartum; Female; Galactorrhea; Humans; Infan | 2004 |
Effect of risperidone on prolactinoma--a case report.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Female; | 2004 |
Olanzapine vs. other antipsychotics in actual out-patient settings: six months tolerability results from the European Schizophrenia Out-patient Health Outcomes study.
Topics: Adult; Ambulatory Care; Amenorrhea; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Clozapin | 2005 |
Risperidone-induced symptomatic hyperprolactinaemia in adolescents.
Topics: Adolescent; Antipsychotic Agents; Drug Monitoring; Female; Galactorrhea; Gynecomastia; Humans; Hyper | 2006 |
Atypical antipsychotics and pituitary tumors: a pharmacovigilance study.
Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Amenorrhea; Antipsychotic Agents; Aripiprazole; | 2006 |
Risperidone-induced polydipsia and polyphagia associated with galactorrhea, abdominal pain, and rapid weight gain in an adolescent Hispanic female.
Topics: Abdominal Pain; Adolescent; Bipolar Disorder; Drinking Behavior; Feeding Behavior; Female; Galactorr | 2007 |
[A naturalistic, observational study of outpatients with schizophrenia: efficacy and safety results after 6 months. The International Schizophrenia Outpatient Health Outcomes study, IC-SOHO].
Topics: Adult; Aggression; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Dibenzo | 2007 |
Risperidone-induced galactorrhea.
Topics: Adult; Antipsychotic Agents; Female; Galactorrhea; Humans; Psychotic Disorders; Risperidone | 1997 |
Risperidone-induced galactorrhea associated with a prolactin elevation.
Topics: Adult; Antipsychotic Agents; Dose-Response Relationship, Drug; Female; Galactorrhea; Humans; Prolact | 1998 |
Olanzapine use in women with antipsychotic-induced hyperprolactinemia.
Topics: Adult; Amenorrhea; Antipsychotic Agents; Benzodiazepines; Female; Galactorrhea; Humans; Hyperprolact | 1998 |
Prolactin levels and adverse events in patients treated with risperidone.
Topics: Adult; Antipsychotic Agents; Female; Galactorrhea; Humans; Male; Prolactin; Randomized Controlled Tr | 1999 |
Galactorrhea and gynecomastia in a hypothyroid male being treated with risperidone.
Topics: Adult; Galactorrhea; Humans; Hypothyroidism; Male; Neurocognitive Disorders; Prolactin; Risperidone; | 2000 |
[Galactorrhea and secondary amenorrhea in hyperprolactinemia].
Topics: Adult; Amenorrhea; Antipsychotic Agents; Diagnosis, Differential; Female; Galactorrhea; Humans; Hype | 2000 |
Risperidone-associated galactorrhea in a male teenager.
Topics: Adolescent; Antipsychotic Agents; Depressive Disorder, Major; Galactorrhea; Humans; Male; Risperidon | 2001 |