Page last updated: 2024-11-03

risperidone and Dystonia

risperidone has been researched along with Dystonia in 46 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)

Research Excerpts

ExcerptRelevanceReference
" CASE REPORT A 27-year-old woman with schizophrenia on risperidone presented to our Emergency Department with a sensation of choking and respiratory distress, mimicking a panic attack."7.96Risperidone-Induced Acute Laryngeal Dystonia: A Case Report. ( Alkharboush, GA; Alsalamah, MA, 2020)
" Overall, 63 (94%) patients experienced at least one treatment-emergent adverse event (TEAE)."6.87A phase II study to evaluate the pharmacokinetics, safety, and tolerability of Risperidone ISM multiple intramuscular injections once every 4 weeks in patients with schizophrenia. ( Anta, L; Ayani, I; Gutierro, I; Litman, RE; Llaudó, J; Martínez, J, 2018)
"Young patients with intellectual disability (ID) have both diagnostic and therapeutic challenges."5.72Top-Up Clozapine for Risperidone LAI-Related Acute Dystonia and TR Bipolar in an Adolescent with ID- ( Alamiri, B; Naguy, A; Pridmore, S; Singh, A, 2022)
" This is the first known case of a patient developing dystonia after chronic use of low-dose olanzapine."5.62Late-Onset Dystonia With Low-Dose Olanzapine in an Older Person: A Case Report. ( Daniel, V; Sanon, M; See, S, 2021)
"Risperidone is a heterocyclic neuroleptic with prominent antiserotoninergic (5HT2) as well as antidopaminergic (D2) activity."5.31Risperidone in idiopathic and symptomatic dystonia: preliminary experience. ( Grassi, E; Latorraca, S; Marini, P; Piacentini, S; Sorbi, S, 2000)
" CASE REPORT A 27-year-old woman with schizophrenia on risperidone presented to our Emergency Department with a sensation of choking and respiratory distress, mimicking a panic attack."3.96Risperidone-Induced Acute Laryngeal Dystonia: A Case Report. ( Alkharboush, GA; Alsalamah, MA, 2020)
"Clozapine is a second-generation antipsychotic typically reserved for refractory psychotic disorders due to its high-risk side effect profile to include agranulocytosis, with its attendant need for regular blood draws."3.91An Unexpected Circumstance: Acute Dystonic Reaction in the Setting of Clozapine Administration. ( Ahmed, I; Kaplan, AM; Pitts, WB, 2019)
" Overall, 63 (94%) patients experienced at least one treatment-emergent adverse event (TEAE)."2.87A phase II study to evaluate the pharmacokinetics, safety, and tolerability of Risperidone ISM multiple intramuscular injections once every 4 weeks in patients with schizophrenia. ( Anta, L; Ayani, I; Gutierro, I; Litman, RE; Llaudó, J; Martínez, J, 2018)
" Adding risperidone to mirtazapine probably does not necessitate a change of the dosage of either drug, but more extensive investigations are needed."2.69Lack of drug interactions between mirtazapine and risperidone in psychiatric patients: a pilot study. ( Doorschot, CH; Loonen, AJ; Oostelbos, MC; Sitsen, JM, 1999)
"Risperidone has these pharmacologic properties."2.39Extrapyramidal side effects and tolerability of risperidone: a review. ( Owens, DG, 1994)
"Young patients with intellectual disability (ID) have both diagnostic and therapeutic challenges."1.72Top-Up Clozapine for Risperidone LAI-Related Acute Dystonia and TR Bipolar in an Adolescent with ID- ( Alamiri, B; Naguy, A; Pridmore, S; Singh, A, 2022)
" This is the first known case of a patient developing dystonia after chronic use of low-dose olanzapine."1.62Late-Onset Dystonia With Low-Dose Olanzapine in an Older Person: A Case Report. ( Daniel, V; Sanon, M; See, S, 2021)
" In the patient with laryngeal dystonia these symptoms appeared after restarting risperidone treatment, in the other patient after diminishing the dosage of risperidone and adding sertindole, and in the third patient the syndrome appeared after beginning ziprasidone."1.37Pisa syndrome and laryngeal dystonia induced by novel antipsychotics. ( Lerner, V; Miodownik, C; Witztum, E, 2011)
"In contrast, tardive dystonia is a long-lasting menace in the course of antipsychotic treatment, for which there is no established therapy."1.30Managing antipsychotic-induced acute and tardive dystonia. ( Raja, M, 1998)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's17 (36.96)18.2507
2000's13 (28.26)29.6817
2010's12 (26.09)24.3611
2020's4 (8.70)2.80

Authors

AuthorsStudies
See, S1
Daniel, V1
Sanon, M1
Naguy, A1
Pridmore, S1
Singh, A1
Alamiri, B1
van Renterghem, L1
Titeca, K1
Crunelle, CL1
Geerts, P1
Matthys, F1
Alkharboush, GA1
Alsalamah, MA1
Çirakli, S1
Kaplan, AM1
Pitts, WB1
Ahmed, I1
Anta, L1
Llaudó, J1
Ayani, I1
Martínez, J1
Litman, RE1
Gutierro, I1
Takaki, M1
Mizuki, Y1
Miki, T1
Abel Boenerjous, RS1
Zirker, W1
Masilamani, S1
Ganesh, M1
Jabbar, U1
Iskander, FH1
Chan, HY1
Chang, CJ1
Chiang, SC1
Chen, JJ1
Chen, CH1
Sun, HJ1
Hwu, HG1
Lai, MS1
Cordeiro, Q1
Zung, S1
Vallada, H1
Lamkin, S1
Buhl, D1
Yagmur, F1
Ulusoy, HB1
Buyukoglan, H1
Kaya, MG1
Page, CB1
Calver, LA1
Isbister, GK1
Miodownik, C1
Lerner, V1
Witztum, E1
Kaufmann, A1
Boesch, S1
Fleischhacker, WW1
Hofer, A1
Sharma, V1
Biswas, DD1
Nakagawa, S1
Koyama, T1
Yohanan, M1
Aulakh, JS1
Weith, J1
Hawkins, JW1
Willemsen, MA1
van der Wal, KG1
Czarnecki, K1
Kumar, N1
Josephs, KA1
Keshen, A1
Carandang, C1
Dickson, R1
Williams, R1
Dalby, JT1
Owens, DG1
Auchus, AP1
Freeman, A1
Green, RC1
Radford, JM1
Brown, TM1
Borison, RL1
Zuddas, A1
Cianchetti, C1
Faulk, RS1
Gilmore, JH1
Jensen, EW1
Perkins, DO1
Simpson, GM2
Meyer, JM1
Anand, HS1
Takhar, J1
Manchanda, R1
Brody, AL1
Brown, ES1
Raja, M1
Chong, SA1
Remington, G1
Tan, CH1
Vercueil, L1
Foucher, J1
Durrenberger, S1
de Leon, J1
Loonen, AJ1
Doorschot, CH1
Oostelbos, MC1
Sitsen, JM1
Kwak, YT1
Han, IW1
Baik, J1
Koo, MS1
Grassi, E1
Latorraca, S1
Piacentini, S1
Marini, P1
Sorbi, S1
Takahashi, H1
Narendran, R1
Young, CM1
Pato, MT1
Harada, K1
Sasaki, N1
Ikeda, H1
Nakano, N1
Ozawa, H1
Saito, T1

Reviews

5 reviews available for risperidone and Dystonia

ArticleYear
Acute Laryngeal Dystonia With Novel Antipsychotics: A Case Report and Review of Literature.
    Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:5

    Topics: Acute Disease; Aged; Antipsychotic Agents; Dystonia; Humans; Laryngeal Diseases; Male; Risperidone;

2015
[Extrapyramidal syndrome].
    Ryoikibetsu shokogun shirizu, 2003, Issue:38

    Topics: Acute Disease; Akathisia, Drug-Induced; Antipsychotic Agents; Basal Ganglia Diseases; Dibenzothiazep

2003
Extrapyramidal side effects and tolerability of risperidone: a review.
    The Journal of clinical psychiatry, 1994, Volume: 55 Suppl

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Clinical Trials as Topic; Dyskinesia, Drug-Induced; D

1994
Assessment of EPS and tardive dyskinesia in clinical trials. Collaborative Working Group on Clinical Trial Evaluations.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 12

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clinical Tri

1998
The treatment of tardive dyskinesia and tardive dystonia.
    The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 4

    Topics: Adult; Akathisia, Drug-Induced; Algorithms; Antipsychotic Agents; Benzodiazepines; Clozapine; Decisi

2000

Trials

4 trials available for risperidone and Dystonia

ArticleYear
A phase II study to evaluate the pharmacokinetics, safety, and tolerability of Risperidone ISM multiple intramuscular injections once every 4 weeks in patients with schizophrenia.
    International clinical psychopharmacology, 2018, Volume: 33, Issue:2

    Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Adm

2018
A randomised controlled study of risperidone and olanzapine for schizophrenic patients with neuroleptic-induced acute dystonia or parkinsonism.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Dystonia; Female; Hu

2010
Efficacy of risperidone in idiopathic segmental dystonia.
    Lancet (London, England), 1996, Jan-13, Volume: 347, Issue:8994

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Dystonia; Female; Humans; Male; Meige Syndrome; Middl

1996
Lack of drug interactions between mirtazapine and risperidone in psychiatric patients: a pilot study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 10, Issue:1

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Depression; Depressive Disorder

1999

Other Studies

37 other studies available for risperidone and Dystonia

ArticleYear
Late-Onset Dystonia With Low-Dose Olanzapine in an Older Person: A Case Report.
    The Senior care pharmacist, 2021, Oct-01, Volume: 36, Issue:10

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Dystonia; Female; Humans; Olanzapine; Risperidone

2021
Top-Up Clozapine for Risperidone LAI-Related Acute Dystonia and TR Bipolar in an Adolescent with ID-
    Psychopharmacology bulletin, 2022, 05-31, Volume: 52, Issue:2

    Topics: Adolescent; Antipsychotic Agents; Clozapine; Dystonia; Dystonic Disorders; Humans; Intellectual Disa

2022
[Oculogyric crisis as an isolated extrapyramidal symptom of auto-intoxication with risperidone].
    Tijdschrift voor psychiatrie, 2019, Volume: 61, Issue:9

    Topics: Antipsychotic Agents; Diagnosis, Differential; Dystonia; Female; Humans; Ocular Motility Disorders;

2019
Risperidone-Induced Acute Laryngeal Dystonia: A Case Report.
    The American journal of case reports, 2020, Jun-07, Volume: 21

    Topics: Adult; Antipsychotic Agents; Benztropine; Dystonia; Female; Humans; Laryngeal Diseases; Risperidone;

2020
Childhood dystonic reactions in the middle Black Sea region.
    Medicine, 2021, Jul-02, Volume: 100, Issue:26

    Topics: Age of Onset; Antipsychotic Agents; Aripiprazole; Biperiden; Child; Disease Susceptibility; Dopamine

2021
An Unexpected Circumstance: Acute Dystonic Reaction in the Setting of Clozapine Administration.
    Journal of pharmacy practice, 2019, Volume: 32, Issue:1

    Topics: Acute Disease; Adult; Antipsychotic Agents; Clozapine; Drug Interactions; Dystonia; Humans; Male; Ps

2019
Blonanserin improved dystonia induced by risperidone or olanzapine in two patients with schizophrenia.
    The Journal of neuropsychiatry and clinical neurosciences, 2014, Apr-01, Volume: 26, Issue:2

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Dystonia; Female; Humans; Olanzapine; Piperazines; Pip

2014
Elderly nursing home resident with head drop.
    Journal of the American Medical Directors Association, 2015, May-01, Volume: 16, Issue:5

    Topics: Aged; Antipsychotic Agents; Dopamine Antagonists; Dystonia; Dystonic Disorders; Female; Humans; Psyc

2015
Pisa syndrome induced by rapid increase and high dosage of risperidone.
    Arquivos de neuro-psiquiatria, 2008, Volume: 66, Issue:4

    Topics: Adolescent; Antipsychotic Agents; Dystonia; Humans; Male; Risperidone; Schizophrenia; Syndrome

2008
Extrapyramidal side effects: could you identify them in the emergency department?
    Journal of emergency nursing, 2009, Volume: 35, Issue:1

    Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Dopamine Antagonists; Dyskinesi

2009
Acute respiratory distress due to antipsychotic drugs.
    Pharmacopsychiatry, 2010, Volume: 43, Issue:3

    Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Drug Therapy, Co

2010
Risperidone overdose causes extrapyramidal effects but not cardiac toxicity.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Antipsychotic Agents; Basal Ganglia Diseases; Databases, Factual; Drug Overdose;

2010
Pisa syndrome and laryngeal dystonia induced by novel antipsychotics.
    The Israel journal of psychiatry and related sciences, 2011, Volume: 48, Issue:3

    Topics: Adult; Antipsychotic Agents; Dystonia; Humans; Imidazoles; Indoles; Laryngeal Diseases; Male; Middle

2011
Management of a risperidone-induced tardive Pisa syndrome: a case report.
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:3

    Topics: Abdomen; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Drug Monitoring; Dystonia; Female; Hu

2012
Antecollis, lingual dystonia, and mutism secondary to risperidone.
    The Journal of neuropsychiatry and clinical neurosciences, 2012,Summer, Volume: 24, Issue:3

    Topics: Antipsychotic Agents; Child; Dystonia; Female; Humans; Intellectual Disability; Mutism; Risperidone;

2012
Pisa syndrome in a patient in a wheelchair taking valproic acid.
    The American journal of psychiatry, 2006, Volume: 163, Issue:2

    Topics: Aged; Anticonvulsants; Antipsychotic Agents; Drug Therapy, Combination; Dystonia; Humans; Male; Psyc

2006
[Medication-induced mandibular luxation in a seven-year-old patient].
    Tijdschrift voor psychiatrie, 2008, Volume: 50, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Dopamine Uptake Inhibitors; Dystonia; Humans;

2008
Parkinsonism and tardive antecollis in frontotemporal dementia--increased sensitivity to newer antipsychotics?
    European journal of neurology, 2008, Volume: 15, Issue:2

    Topics: Antipsychotic Agents; Benzodiazepines; Dementia; Dibenzothiazepines; Dystonia; Humans; Male; Middle

2008
Acute dystonic reaction in an adolescent on risperidone when a concomitant stimulant medication is discontinued.
    Journal of child and adolescent psychopharmacology, 2007, Volume: 17, Issue:6

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys

2007
Dystonic reaction and relapse with clozapine discontinuation and risperidone intiation.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1994, Volume: 39, Issue:3

    Topics: Adult; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedu

1994
Agitated behavior relieved following treatment of cervical dystonia in dementia.
    Neurology, 1995, Volume: 45, Issue:2

    Topics: Alzheimer Disease; Botulinum Toxins; Chlorpromazine; Dystonia; Female; Humans; Isoxazoles; Middle Ag

1995
Unexpected dystonia while changing from clozapine to risperidone.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:3

    Topics: Adult; Antipsychotic Agents; Clozapine; Dystonia; Humans; Isoxazoles; Male; Piperidines; Risperidone

1995
Risperidone-induced dystonic reaction.
    The American journal of psychiatry, 1996, Volume: 153, Issue:4

    Topics: Adult; Antipsychotic Agents; Dystonia; Humans; Male; Ocular Motility Disorders; Risperidone; Schizop

1996
Dystonia while changing from clozapine to risperidone.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:3

    Topics: Antipsychotic Agents; Clozapine; Drug Interactions; Dystonia; Humans; Risperidone

1996
Re: Acute dystonic reaction with risperidone.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1996, Volume: 41, Issue:6

    Topics: Dystonia; Humans; Risperidone

1996
Acute dystonic reaction with risperidone.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1996, Volume: 41, Issue:1

    Topics: Adolescent; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Dy

1996
Acute dystonia induced by rapid increase in risperidone dosage.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:6

    Topics: Acute Disease; Adult; Antipsychotic Agents; Dystonia; Humans; Male; Risperidone; Schizophrenia, Para

1996
Extrapyramidal side effects with low-dose risperidone.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1997, Volume: 42, Issue:3

    Topics: Adult; Antipsychotic Agents; Delusions; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced;

1997
Managing antipsychotic-induced acute and tardive dystonia.
    Drug safety, 1998, Volume: 19, Issue:1

    Topics: Antipsychotic Agents; Cholinergic Antagonists; Clozapine; Dyskinesia, Drug-Induced; Dystonia; Humans

1998
Risperidone treatment of tardive dyskinesia and dystonia.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:5

    Topics: Antipsychotic Agents; Diazepam; Dopamine Antagonists; Drug Administration Schedule; Drug Therapy, Co

1999
Risperidone-induced tardive dystonia and psychosis.
    Lancet (London, England), 1999, Mar-20, Volume: 353, Issue:9157

    Topics: Antipsychotic Agents; Benzodiazepines; Dystonia; Facial Muscles; Humans; Male; Middle Aged; Neck Mus

1999
Acute dystonic reaction to lithium and risperidone.
    The Journal of neuropsychiatry and clinical neurosciences, 1999,Fall, Volume: 11, Issue:4

    Topics: Acute Disease; Aged; Aged, 80 and over; Antimanic Agents; Antipsychotic Agents; Dystonia; Humans; Li

1999
Relation between cholinesterase inhibitor and Pisa syndrome.
    Lancet (London, England), 2000, Jun-24, Volume: 355, Issue:9222

    Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Donepezil; Dopamine Antagonists; Dys

2000
Risperidone in idiopathic and symptomatic dystonia: preliminary experience.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2000, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Dopamine Antagonists; Dystonia; Humans; Hypnotics and Sedatives; Male; Middle Age

2000
Acute dystonia induced by adding midodrine, a selective alpha 1 agonist, to risperidone in a patient with catatonic schizophrenia.
    The Journal of neuropsychiatry and clinical neurosciences, 2000,Spring, Volume: 12, Issue:2

    Topics: Acute Disease; Adrenergic alpha-Agonists; Adult; Antipsychotic Agents; Dystonia; Female; Humans; Mid

2000
Possible risperidone-induced tardive dystonia.
    The Annals of pharmacotherapy, 2000, Volume: 34, Issue:12

    Topics: Age of Onset; Dopamine Antagonists; Dystonia; Humans; Male; Middle Aged; Risperidone

2000
Risperidone-induced Pisa syndrome.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:2

    Topics: Adult; Antipsychotic Agents; Dystonia; Humans; Male; Risperidone; Schizophrenia; Syndrome

2002