Page last updated: 2024-11-03

risperidone and Dyslipidemias

risperidone has been researched along with Dyslipidemias in 13 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Dyslipidemias: Abnormalities in the serum levels of LIPIDS, including overproduction or deficiency. Abnormal serum lipid profiles may include high total CHOLESTEROL, high TRIGLYCERIDES, low HIGH DENSITY LIPOPROTEIN CHOLESTEROL, and elevated LOW DENSITY LIPOPROTEIN CHOLESTEROL.

Research Excerpts

ExcerptRelevanceReference
"Risperidone use in children and adolescents is associated with the development of metabolic disorders including increased accumulation of body fat, dyslipidemia, and glucose and insulin metabolism dysregulation."7.96Exercise intervention for preventing risperidone-induced dyslipidemia and gluco-metabolic disorders in female juvenile rats. ( Deng, C; Han, M; Sylvester, E; Yi, W, 2020)
"Risperidone use in children and adolescents is associated with the development of metabolic disorders including increased accumulation of body fat, dyslipidemia, and glucose and insulin metabolism dysregulation."3.96Exercise intervention for preventing risperidone-induced dyslipidemia and gluco-metabolic disorders in female juvenile rats. ( Deng, C; Han, M; Sylvester, E; Yi, W, 2020)
"Children treated with risperidone or quetiapine are at a significant risk for developing obesity, elevated waist circumference, and dyslipidemia during 12 months of treatment."3.81Increased Risk of Obesity and Metabolic Dysregulation Following 12 Months of Second-Generation Antipsychotic Treatment in Children: A Prospective Cohort Study. ( Davidson, J; Nguyen, D; Panagiotopoulos, C; Ronsley, R, 2015)
"RLAI and OP show good short- and long-term safety when treating patients with schizophrenia, with uncommon discontinuation due to adverse effects."2.46Long-acting atypical injectable antipsychotics in the treatment of schizophrenia: safety and tolerability review. ( Cañas, F; Möller, HJ, 2010)
"Data for 60,162 subjects with type 1 diabetes up to the age of 25 years registered in the nationwide German/Austrian Diabetes Survey were included in the analysis."1.42Comparison of glycemic and metabolic control in youth with type 1 diabetes with and without antipsychotic medication: analysis from the nationwide German/Austrian Diabetes Survey (DPV). ( Bartus, B; Bollow, E; Galler, A; Haberland, H; Holl, RW; Meusers, M; Näke, A; Schober, E, 2015)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (46.15)29.6817
2010's6 (46.15)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Sylvester, E1
Yi, W1
Han, M1
Deng, C1
Pisano, S1
Gritti, A1
Catone, G1
Pascotto, A1
Galler, A1
Bollow, E1
Meusers, M1
Bartus, B1
Näke, A1
Haberland, H1
Schober, E1
Holl, RW1
Bonaccorso, S1
Sodhi, M1
Li, J1
Bobo, WV1
Chen, Y1
Tumuklu, M1
Theleritis, C1
Jayathilake, K1
Meltzer, HY1
Ronsley, R1
Nguyen, D1
Davidson, J1
Panagiotopoulos, C1
Lee, E1
Leung, CM1
Duncan, EJ1
Woolson, SL1
Hamer, RM1
Dunlop, BW1
Cañas, F1
Möller, HJ1
Adeneye, AA1
Agbaje, EO1
Olagunju, JA1
Lin, SK1
Chen, CK1
Wooten, J1
Perlis, RH1
Perez-Iglesias, R1
Crespo-Facorro, B1
Amado, JA1
Garcia-Unzueta, MT1
Ramirez-Bonilla, ML1
Gonzalez-Blanch, C1
Martinez-Garcia, O1
Vazquez-Barquero, JL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Monitoring of Metabolic Adverse Events of Second Generation Antipsychotics in a Naive Pediatric Population Followed in Mental Health Outpatient and Inpatient Clinical Settings (MEMAS Prospective Study)[NCT04395326]120 participants (Anticipated)Observational2017-01-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for risperidone and Dyslipidemias

ArticleYear
Long-acting atypical injectable antipsychotics in the treatment of schizophrenia: safety and tolerability review.
    Expert opinion on drug safety, 2010, Volume: 9, Issue:5

    Topics: Administration, Oral; Antipsychotic Agents; Benzodiazepines; Delayed-Action Preparations; Dyslipidem

2010
Metabolic effects of the atypical antipsychotics.
    Southern medical journal, 2007, Volume: 100, Issue:8

    Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Diabetes Mellitus; Dibenzothiazepine

2007
Treatment of bipolar disorder: the evolving role of atypical antipsychotics.
    The American journal of managed care, 2007, Volume: 13, Issue:7 Suppl

    Topics: Antipsychotic Agents; Aripiprazole; Arrhythmias, Cardiac; Benzodiazepines; Bipolar Disorder; Diabete

2007

Trials

2 trials available for risperidone and Dyslipidemias

ArticleYear
The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with increased body mass index and insulin resistance measures in bipolar disorder and schizophrenia.
    Bipolar disorders, 2015, Volume: 17, Issue:5

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Blood Glucose; Body Mass In

2015
A 12-week randomized clinical trial to evaluate metabolic changes in drug-naive, first-episode psychosis patients treated with haloperidol, olanzapine, or risperidone.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:11

    Topics: Adolescent; Adult; Anthropometry; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Body Mass In

2007

Other Studies

8 other studies available for risperidone and Dyslipidemias

ArticleYear
Exercise intervention for preventing risperidone-induced dyslipidemia and gluco-metabolic disorders in female juvenile rats.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 199

    Topics: Animals; Antipsychotic Agents; Blood Glucose; Body Mass Index; Dyslipidemias; Female; Glucose Tolera

2020
Antipsychotic-induced dyslipidemia treated with omega 3 fatty acid supplement in an 11-year-old psychotic child: a 1-year follow-up.
    Journal of child and adolescent psychopharmacology, 2013, Volume: 23, Issue:2

    Topics: Antipsychotic Agents; Child; Dietary Supplements; Dyslipidemias; Fatty Acids, Omega-3; Follow-Up Stu

2013
Comparison of glycemic and metabolic control in youth with type 1 diabetes with and without antipsychotic medication: analysis from the nationwide German/Austrian Diabetes Survey (DPV).
    Diabetes care, 2015, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Albuminuria; Antipsychotic Agents; Blood Glucose; Body Mass Index; Diabetes Compl

2015
Increased Risk of Obesity and Metabolic Dysregulation Following 12 Months of Second-Generation Antipsychotic Treatment in Children: A Prospective Cohort Study.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2015, Volume: 60, Issue:10

    Topics: Adolescent; Antipsychotic Agents; Anxiety Disorders; Attention Deficit and Disruptive Behavior Disor

2015
Atypical antipsychotics and metabolic outcomes in Chinese patients: a comparison of olanzapine and risperidone.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:6

    Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; China; Cross-Sectional Studies; Dose-Response Re

2008
Risk of lipid abnormality with haloperidol, olanzapine, quetiapine, and risperidone in a Veterans Affairs population.
    International clinical psychopharmacology, 2009, Volume: 24, Issue:4

    Topics: Antipsychotic Agents; Benzodiazepines; Case-Control Studies; Dibenzothiazepines; Dyslipidemias; Fema

2009
Metformin: an effective attenuator of risperidone-induced insulin resistance hyperglycemia and dyslipidemia in rats.
    Indian journal of experimental biology, 2011, Volume: 49, Issue:5

    Topics: Animals; Antipsychotic Agents; Blood Glucose; Disease Models, Animal; Dyslipidemias; Glyburide; Huma

2011
Reversal of antipsychotic-induced hyperprolactinemia, weight gain, and dyslipidemia by aripiprazole: A case report.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:8

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Dyslipidemias; Female; Humans; Hyperprolactinemia; Obesit

2006