Page last updated: 2024-11-03

risperidone and Drug-Related Side Effects and Adverse Reactions

risperidone has been researched along with Drug-Related Side Effects and Adverse Reactions in 42 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Drug-Related Side Effects and Adverse Reactions: Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.

Research Excerpts

ExcerptRelevanceReference
"Sertindole and risperidone are effective and well-tolerated in patients with treatment-resistant schizophrenia."9.15A double-blind, randomized study comparing the efficacy and safety of sertindole and risperidone in patients with treatment-resistant schizophrenia. ( Buckley, PF; Daniel, DG; Kane, JM; Potkin, SG, 2011)
"This cross-sectional study aimed to compare the effects of treatment with an atypical antipsychotic drug (olanzapine or risperidone) on quality of life (QoL) and to document adverse effects in 115 patients diagnosed with schizophrenia who attended the ambulatory service of Hospital Dr."7.79Quality of life and adverse effects of olanzapine versus risperidone therapy in patients with schizophrenia. ( Chaves, KM; de Araújo Júnior, RF; de Araújo, AA; de Paula Soares Rachetti, V; do Socorro Costa Feitosa Alves, M; Filgueira Júnior, A; Guerra, GC; Ribeiro, SB; Serrano-Blanco, A; Soares, LA, 2013)
" We hypothesized that a low dose of risperidone in combination with sertraline would reduce serious adverse effects without decreasing treatment response."7.30Efficacy of low-dose risperidone in combination with sertraline in first-episode drug-naïve patients with schizophrenia: a randomized controlled open-label study. ( Lang, X; Wu, F; Xiu, M; Xue, M; Zang, X; Zhang, X, 2023)
"Schizophrenia is a severe disorder that significantly affects the quality of life and total functioning of patients and their caregivers."6.50Individualizing clozapine and risperidone treatment for schizophrenia patients. ( Assimakopoulos, K; Bartsakoulia, M; Iconomou, G; Mitropoulos, K; Papadima, EM; Patrinos, GP; Squassina, A; Tsermpini, EE, 2014)
"Adverse changes in adiposity and insulin sensitivity were observed during 12 weeks of antipsychotic treatment in youths, with the greatest fat increases on olanzapine."5.27Metabolic Effects of Antipsychotics on Adiposity and Insulin Sensitivity in Youths: A Randomized Clinical Trial. ( Flavin, KS; Newcomer, JW; Nicol, GE; Patterson, BW; Schechtman, KB; Schweiger, JA; Yingling, MD, 2018)
"Sertindole and risperidone are effective and well-tolerated in patients with treatment-resistant schizophrenia."5.15A double-blind, randomized study comparing the efficacy and safety of sertindole and risperidone in patients with treatment-resistant schizophrenia. ( Buckley, PF; Daniel, DG; Kane, JM; Potkin, SG, 2011)
" (2) Articles published between 2004 and 2008 were identified by a PubMed search with the keywords weight gain, metabolic, glucose, insulin, and lipid AND dose combined with amisulpride, aripiprazole, clozapine, quetiapine, risperidone, sertindole, and ziprasidone."4.85Are weight gain and metabolic side effects of atypical antipsychotics dose dependent? A literature review. ( De Hert, M; Simon, V; van Winkel, R, 2009)
"A wide variety of patient groups may benefit from treatment with long-acting risperidone, including patients with suboptimal efficacy, particularly as a result of partial compliance, patients experiencing side-effects with another antipsychotic agent or those with a first episode of schizophrenia."4.83Clinical experience and management considerations with long-acting risperidone. ( Parellada, E, 2006)
"Paliperidone palmitate (PP), a long-acting intramuscular formulation of paliperidone, has been marketed in Europe within the last 10 years and provides an important treatment option for patients with schizophrenia."4.02Fatal and life-threatening ADRs associated with paliperidone palmitate: an observational study in the French pharmacovigilance database. ( Boels, D; Citterio-Quentin, A; Jolliet, P; Mahé, J; Moragny, J; Olry, A, 2021)
"This cross-sectional study compared quality of life and side effects in 108 users of olanzapine or risperidone suffering schizophrenia and being attended at psychiatric ambulatory services in Rio Grande do Norte, Brazil."3.83Quality of Life and Hormonal, Biochemical, and Anthropometric Profile Between Olanzapine and Risperidone Users. ( de Araújo Júnior, RF; de Araújo, AA; Dos Santos, AC; Guerra, GC; Lemos, TM; Medeiros, CA; Ribeiro, SB; Rubio-Valera, M; Serrano-Blanco, A, 2016)
"This cross-sectional study aimed to compare the effects of treatment with an atypical antipsychotic drug (olanzapine or risperidone) on quality of life (QoL) and to document adverse effects in 115 patients diagnosed with schizophrenia who attended the ambulatory service of Hospital Dr."3.79Quality of life and adverse effects of olanzapine versus risperidone therapy in patients with schizophrenia. ( Chaves, KM; de Araújo Júnior, RF; de Araújo, AA; de Paula Soares Rachetti, V; do Socorro Costa Feitosa Alves, M; Filgueira Júnior, A; Guerra, GC; Ribeiro, SB; Serrano-Blanco, A; Soares, LA, 2013)
" We hypothesized that a low dose of risperidone in combination with sertraline would reduce serious adverse effects without decreasing treatment response."3.30Efficacy of low-dose risperidone in combination with sertraline in first-episode drug-naïve patients with schizophrenia: a randomized controlled open-label study. ( Lang, X; Wu, F; Xiu, M; Xue, M; Zang, X; Zhang, X, 2023)
"Genetic variants in pharmacodynamic genes could represent valuable markers of AR risk and antipsychotic safety."2.78Pharmacodynamic genetic variants related to antipsychotic adverse reactions in healthy volunteers. ( Abad-Santos, F; Ayuso, C; Borobia, AM; Cabaleiro, T; Carcas, AJ; López-Rodríguez, R; Novalbos, J; Ochoa, D; Román, M, 2013)
" The most common dosage of RLAI used at endpoint was 25 mg every 14 days (60%)."2.73Long-term safety and efficacy of long-acting risperidone in elderly psychotic patients. ( Glue, P; Kissling, W; Medori, R; Simpson, S, 2007)
"Preschool children tolerated low-dose risperidone well with no serious adverse effects observed over a 6-month treatment period."2.72Risperidone in preschool children with autistic spectrum disorders: an investigation of safety and efficacy. ( Belden, A; Heffelfinger, A; Luby, J; Mrakotsky, C; Spitznagel, E; Stalets, MM; Williams, M, 2006)
"Schizophrenia is a severe disorder that significantly affects the quality of life and total functioning of patients and their caregivers."2.50Individualizing clozapine and risperidone treatment for schizophrenia patients. ( Assimakopoulos, K; Bartsakoulia, M; Iconomou, G; Mitropoulos, K; Papadima, EM; Patrinos, GP; Squassina, A; Tsermpini, EE, 2014)
" Although there are some reports in literature, the side effect profile in this population remains poorly defined and there is a need to raise awareness among clinicians across specialties."1.91Recognising side effects of antipsychotics in children with intellectual disabilities. ( Anand, G; Lee, J; Shepperd, R; Smith, M, 2023)
"Retrospective studies using spontaneous reporting system databases have provided a great understanding of adverse drug reactions (ADRs) in the real world, complementing the data obtained from randomized controlled trials."1.72Characteristics of adverse reactions among antipsychotic drugs using the Korean Adverse Event Reporting System database from 2010 to 2019. ( Byeon, SJ; Chung, SJ; Oh, S, 2022)
"Lithium carbonate was associated with increased risks of rash (PT), drug interaction (PT), and tubulointerstitial diseases (SMQ)."1.72Analysis of adverse drug events in patients with bipolar disorders using the Japanese Adverse Drug Event Report database. ( Nabekura, T; Uwai, Y, 2022)
"Drug-induced weight gain is a profound side effect of numerous commonly used medications."1.72Drug-induced weight gain in the last 10 years: a descriptive study. ( Ahmed, NJ; Alahmari, A; Almalki, ZS; Alshehri, AM, 2022)
"There were significant gaps in adverse effect monitoring in this cohort."1.51Adherence to Antipsychotic Adverse Effect Monitoring Among a Referred Sample of Children with Intellectual Disabilities. ( Javaheri, KR; McLennan, JD, 2019)
" Total dyskinesia score (DyskinesiaS) and total Parkinson score (ParkinsonS) were calculated from the Maryland Psychiatric Research Center Involuntary Movement Scale, total UKU-Cognition score was calculated from the UKU Side Effect Rating Scale."1.42Neurological Adverse Effects of Antipsychotics in Children and Adolescents. ( Alda, JA; Andrés Nestares, P; Arango, C; Baeza, I; Cantarero, CM; Castro-Fornieles, J; de la Serna, E; Garcia-Amador, M; Merchán-Naranjo, J; Moreno, C; Muñoz, D; Tapia, C, 2015)
"Weight gain was found to be lower in the elderly for antipsychotic drugs, in particular for olanzapine."1.39Age and adverse drug reactions from psychopharmacological treatment: data from the AMSP drug surveillance programme in Switzerland. ( Baumann, P; Greil, W; Grohmann, R; Häberle, A; Schuhmann, T, 2013)
" Thus, the aim of this study was to investigate the putative association of genetic markers with the occurrence of four frequently observed adverse events secondary to risperidone treatment: sleepiness, weight gain, extrapyramidal symptoms and sexual adverse events."1.39Association of common genetic variants with risperidone adverse events in a Spanish schizophrenic population. ( Abad-Santos, F; Almoguera, B; Ayuso, C; Baca-García, E; Dal-Ré, R; Dorado, P; Fernandez-Piqueras, J; Llerena, A; Lopez-Castroman, J; Riveiro-Alvarez, R; Vaquero-Lorenzo, C, 2013)
" There was a dose-response relation for all drugs except quetiapine."1.38Differential risk of death in older residents in nursing homes prescribed specific antipsychotic drugs: population based cohort study. ( Avorn, J; Crystal, S; Gerhard, T; Huybrechts, KF; Levin, R; Lucas, JA; Olfson, M; Schneeweiss, S, 2012)
"5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects."1.32Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.38)18.2507
2000's8 (19.05)29.6817
2010's22 (52.38)24.3611
2020's11 (26.19)2.80

Authors

AuthorsStudies
Matthews, EJ1
Kruhlak, NL1
Weaver, JL1
Benz, RD1
Contrera, JF1
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W1
Morgan, RE1
van Staden, CJ1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Afshari, CA1
Hamadeh, HK1
Oh, S1
Byeon, SJ1
Chung, SJ1
Eaton, C1
Yong, K1
Walter, V1
Mbizvo, GK1
Rhodes, S1
Chin, RF1
Uwai, Y1
Nabekura, T1
Ahmed, NJ1
Alshehri, AM1
Almalki, ZS1
Alahmari, A1
Lee, J1
Shepperd, R1
Smith, M1
Anand, G1
Seifert, J1
Maier, HB1
Toto, S1
Dabbert, D1
Lang, X1
Xue, M1
Zang, X1
Wu, F1
Xiu, M1
Zhang, X1
Maruf, AA1
Stein, K1
Arnold, PD1
Aitchison, KJ1
Müller, DJ1
Bousman, C1
Das, A1
Boels, D1
Mahé, J1
Olry, A1
Citterio-Quentin, A1
Moragny, J1
Jolliet, P1
Nicol, GE2
Ivanov, I1
Rafaniello, C1
Sessa, M1
Bernardi, FF1
Pozzi, M1
Cheli, S1
Cattaneo, D1
Baldelli, S1
Molteni, M1
Bernardini, R1
Rossi, F1
Clementi, E1
Bravaccio, C1
Radice, S1
Capuano, A1
Schoretsanitis, G1
Drukker, M1
Van Os, J1
Schruers, KRJ1
Bak, M1
Yingling, MD1
Flavin, KS1
Schweiger, JA1
Patterson, BW1
Schechtman, KB1
Newcomer, JW1
Eugene, AR2
Eugene, B2
Javaheri, KR1
McLennan, JD1
Downing, L1
Kim, DD1
Procyshyn, RM`1
Tibbo, P1
Greil, W1
Häberle, A1
Schuhmann, T1
Grohmann, R1
Baumann, P1
López-Rodríguez, R1
Cabaleiro, T1
Ochoa, D1
Román, M1
Borobia, AM1
Carcas, AJ1
Ayuso, C2
Novalbos, J1
Abad-Santos, F2
Ameis, SH1
Corbett-Dick, P1
Cole, L1
Correll, CU1
Tsermpini, EE1
Assimakopoulos, K1
Bartsakoulia, M1
Iconomou, G1
Papadima, EM1
Mitropoulos, K1
Squassina, A1
Patrinos, GP1
de Araújo, AA2
Ribeiro, SB2
Dos Santos, AC1
Lemos, TM1
Medeiros, CA1
Guerra, GC2
de Araújo Júnior, RF2
Serrano-Blanco, A2
Rubio-Valera, M1
Garcia-Amador, M1
Merchán-Naranjo, J1
Tapia, C1
Moreno, C1
Castro-Fornieles, J1
Baeza, I1
de la Serna, E1
Alda, JA1
Muñoz, D1
Andrés Nestares, P1
Cantarero, CM1
Arango, C1
Nikvarz, N1
Alaghband-Rad, J1
Tehrani-Doost, M1
Alimadadi, A1
Ghaeli, P1
Polcwiartek, C1
Vang, T1
Bruhn, CH1
Hashemi, N1
Rosenzweig, M1
Nielsen, J1
Simon, V1
van Winkel, R1
De Hert, M1
Wittmann, M1
Hausner, H1
Hajak, G1
Haen, E1
Singh, D1
O'Connor, DW1
Klemperer, D1
Kane, JM1
Potkin, SG1
Daniel, DG1
Buckley, PF1
Almoguera, B1
Riveiro-Alvarez, R1
Lopez-Castroman, J1
Dorado, P1
Vaquero-Lorenzo, C1
Fernandez-Piqueras, J1
Llerena, A1
Baca-García, E1
Dal-Ré, R1
Huybrechts, KF1
Gerhard, T1
Crystal, S1
Olfson, M1
Avorn, J1
Levin, R1
Lucas, JA1
Schneeweiss, S1
Chaves, KM1
Soares, LA1
do Socorro Costa Feitosa Alves, M1
de Paula Soares Rachetti, V1
Filgueira Júnior, A1
Parellada, E1
Luby, J1
Mrakotsky, C1
Stalets, MM1
Belden, A1
Heffelfinger, A1
Williams, M1
Spitznagel, E1
Madhusoodanan, S1
Bogunovic, O1
Hendset, M1
Hermann, M1
Kissling, W1
Glue, P1
Medori, R1
Simpson, S1
Mackay, FJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double Blind, Placebo Controlled, Crossover Study of Extended Release Methylphenidate for Treatment of ADHD in Children With Epilepsy[NCT00323947]Phase 433 participants (Actual)Interventional2003-05-31Completed
Metabolic Effects of Antipsychotics in Children[NCT00205699]Phase 4144 participants (Actual)Interventional2006-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in DEXA % Body Fat

This study hypothesized that antipsychotic treatment would increase percent total body fat, as measured by whole body dual energy x-ray absorptiometry (DEXA), with larger adverse effects for olanzapine. (NCT00205699)
Timeframe: 12 weeks

Interventionpercent body fat (Mean)
Risperidone1.81
Olanzapine4.12
Aripiprazole1.66

Change in Insulin-stimulated Glucose Rate of Appearance (Glucose Ra)

This study hypothesized that antipsychotic treatment would decrease hepatic insulin sensitivity, as measured by the rate of appearance of glucose (glucose Ra), with larger adverse effects for olanzapine. (NCT00205699)
Timeframe: 12 weeks

Interventionpercentage of % change (Mean)
Risperidone-2.50
Olanzapine-6.57
Aripiprazole-3.27

Change in Insulin-stimulated Glucose Rate of Disappearance (Glucose Rd)

This study hypothesized that antipsychotic treatment would decrease insulin sensitivity at muscle, as measured by the insulin-stimulated rate of disappearance of glucose (glucose Rd), with larger adverse effects for olanzapine. (NCT00205699)
Timeframe: 12 weeks

Interventionpercentage of % change (Mean)
Risperidone2.30
Olanzapine-29.34
Aripiprazole-30.26

Change in Insulin-stimulated Glycerol Rate of Appearance (Glycerol Ra)

This study hypothesized that antipsychotic treatment would decrease insulin sensitivity at adipose tissue, as measured by the insulin-stimulated rate of disappearance of glycerol (glycerol Ra), with larger adverse effects for olanzapine. (NCT00205699)
Timeframe: 12 weeks

Interventionpercentage of % change (Mean)
Risperidone-3.65
Olanzapine-8.29
Aripiprazole1.70

Change in MRI-measured Subcutaneous Abdominal Fat

This study hypothesized that antipsychotic treatment would increase subcutaneous abdominal fat, as measured by abdominal magnetic resonance imaging (MRI), with larger adverse effects for olanzapine. (NCT00205699)
Timeframe: 12 weeks

InterventionChange in cm-squared (Mean)
Risperidone18.21
Olanzapine34.27
Aripiprazole15.84

Change in MRI-measured Visceral Abdominal Fat

This study hypothesized that antipsychotic treatment would increase visceral abdominal fat, as measured by abdominal magnetic resonance imaging (MRI), with larger adverse effects for olanzapine. (NCT00205699)
Timeframe: 12 weeks

InterventionChange in cm-squared (Mean)
Risperidone6.85
Olanzapine10.73
Aripiprazole12.04

Reviews

8 reviews available for risperidone and Drug-Related Side Effects and Adverse Reactions

ArticleYear
Stimulant and non-stimulant drug therapy for people with attention deficit hyperactivity disorder and epilepsy.
    The Cochrane database of systematic reviews, 2022, 07-13, Volume: 7

    Topics: Adolescent; Adult; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Central Nervous S

2022
    Journal of child and adolescent psychopharmacology, 2021, Volume: 31, Issue:1

    Topics: Adolescent; Antipsychotic Agents; Child; Cytochrome P-450 CYP2D6; Drug-Related Side Effects and Adve

2021
No differences in olanzapine- and risperidone-related weight gain between women and men: a meta-analysis of short- and middle-term treatment.
    Acta psychiatrica Scandinavica, 2018, Volume: 138, Issue:2

    Topics: Adult; Aged; Antipsychotic Agents; Body Mass Index; Drug-Related Side Effects and Adverse Reactions;

2018
Individualizing clozapine and risperidone treatment for schizophrenia patients.
    Pharmacogenomics, 2014, Volume: 15, Issue:1

    Topics: Clozapine; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmacogenetics; Precision Medi

2014
Diabetic ketoacidosis in patients exposed to antipsychotics: a systematic literature review and analysis of Danish adverse drug event reports.
    Psychopharmacology, 2016, Volume: 233, Issue:21-22

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Blood Glucose; Clozapine; Denmark; Diabe

2016
Are weight gain and metabolic side effects of atypical antipsychotics dose dependent? A literature review.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:7

    Topics: Adolescent; Adult; Antipsychotic Agents; Child; Clozapine; Controlled Clinical Trials as Topic; Dose

2009
Efficacy and safety of risperidone long-acting injection in elderly people with schizophrenia.
    Clinical interventions in aging, 2009, Volume: 4

    Topics: Aged; Antipsychotic Agents; Delayed-Action Preparations; Drug-Related Side Effects and Adverse React

2009
Clinical experience and management considerations with long-acting risperidone.
    Current medical research and opinion, 2006, Volume: 22, Issue:2

    Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Delayed-Action Preparations; Drug-Related Sid

2006

Trials

6 trials available for risperidone and Drug-Related Side Effects and Adverse Reactions

ArticleYear
Efficacy of low-dose risperidone in combination with sertraline in first-episode drug-naïve patients with schizophrenia: a randomized controlled open-label study.
    Journal of translational medicine, 2023, 07-04, Volume: 21, Issue:1

    Topics: Antipsychotic Agents; Drug-Related Side Effects and Adverse Reactions; Humans; Prolactin; Risperidon

2023
Metabolic Effects of Antipsychotics on Adiposity and Insulin Sensitivity in Youths: A Randomized Clinical Trial.
    JAMA psychiatry, 2018, 08-01, Volume: 75, Issue:8

    Topics: Abdominal Fat; Absorptiometry, Photon; Adolescent; Antipsychotic Agents; Aripiprazole; Child; Drug-R

2018
Pharmacodynamic genetic variants related to antipsychotic adverse reactions in healthy volunteers.
    Pharmacogenomics, 2013, Volume: 14, Issue:10

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Biomarkers, Pharmacological; Dibenzothiazepines; Drug-

2013
A double-blind, randomized study comparing the efficacy and safety of sertindole and risperidone in patients with treatment-resistant schizophrenia.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:2

    Topics: Adult; Antipsychotic Agents; Double-Blind Method; Drug Resistance; Drug-Related Side Effects and Adv

2011
Risperidone in preschool children with autistic spectrum disorders: an investigation of safety and efficacy.
    Journal of child and adolescent psychopharmacology, 2006, Volume: 16, Issue:5

    Topics: Antipsychotic Agents; Anxiety; Autistic Disorder; Behavior Therapy; Child Behavior Disorders; Child,

2006
Long-term safety and efficacy of long-acting risperidone in elderly psychotic patients.
    Human psychopharmacology, 2007, Volume: 22, Issue:8

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Antipsychotic Agents; Delayed-Action Preparatio

2007

Other Studies

28 other studies available for risperidone and Drug-Related Side Effects and Adverse Reactions

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru

2004
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Characteristics of adverse reactions among antipsychotic drugs using the Korean Adverse Event Reporting System database from 2010 to 2019.
    Journal of psychopharmacology (Oxford, England), 2022, Volume: 36, Issue:9

    Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Child; Cl

2022
Analysis of adverse drug events in patients with bipolar disorders using the Japanese Adverse Drug Event Report database.
    Die Pharmazie, 2022, 09-01, Volume: 77, Issue:7

    Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Drug

2022
Drug-induced weight gain in the last 10 years: a descriptive study.
    Die Pharmazie, 2022, 10-01, Volume: 77, Issue:10

    Topics: Adalimumab; Adverse Drug Reaction Reporting Systems; Aripiprazole; Databases, Factual; Drug-Related

2022
Recognising side effects of antipsychotics in children with intellectual disabilities.
    BMJ case reports, 2023, Jan-04, Volume: 16, Issue:1

    Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Child; Drug-Related Side Effects and Adverse Reactio

2023
[Clinical use of psychotropic drugs: A look at antipsychotic drugs].
    Deutsche medizinische Wochenschrift (1946), 2023, Volume: 148, Issue:9

    Topics: Aged; Antipsychotic Agents; Dementia; Drug-Related Side Effects and Adverse Reactions; Humans; Psych

2023
Janssen Pharmaceutica, Long-Acting Risperidone and Public Health Program of India.
    Community mental health journal, 2021, Volume: 57, Issue:4

    Topics: Antipsychotic Agents; Drug-Related Side Effects and Adverse Reactions; Humans; India; Public Health;

2021
Fatal and life-threatening ADRs associated with paliperidone palmitate: an observational study in the French pharmacovigilance database.
    Clinical toxicology (Philadelphia, Pa.), 2021, Volume: 59, Issue:9

    Topics: Adult; Age Factors; Aged; Antipsychotic Agents; Drug-Related Side Effects and Adverse Reactions; Fem

2021
Getting to Precision Psychopharmacology in Child Psychiatry: The Value of Adverse Treatment Effects.
    Journal of child and adolescent psychopharmacology, 2021, Volume: 31, Issue:1

    Topics: Antipsychotic Agents; Aripiprazole; Child; Child Psychiatry; Drug-Related Side Effects and Adverse R

2021
The predictive value of ABCB1, ABCG2, CYP3A4/5 and CYP2D6 polymorphisms for risperidone and aripiprazole plasma concentrations and the occurrence of adverse drug reactions.
    The pharmacogenomics journal, 2018, 05-22, Volume: 18, Issue:3

    Topics: Adolescent; Aripiprazole; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transp

2018
An opportunity for clinical pharmacology trained physicians to improve patient drug safety: A retrospective analysis of adverse drug reactions in teenagers.
    F1000Research, 2018, Volume: 7

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Biomarkers; Child; Child, Preschool; Databases,

2018
An opportunity for clinical pharmacology trained physicians to improve patient drug safety: A retrospective analysis of adverse drug reactions in teenagers.
    F1000Research, 2018, Volume: 7

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Biomarkers; Child; Child, Preschool; Databases,

2018
An opportunity for clinical pharmacology trained physicians to improve patient drug safety: A retrospective analysis of adverse drug reactions in teenagers.
    F1000Research, 2018, Volume: 7

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Biomarkers; Child; Child, Preschool; Databases,

2018
An opportunity for clinical pharmacology trained physicians to improve patient drug safety: A retrospective analysis of adverse drug reactions in teenagers.
    F1000Research, 2018, Volume: 7

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Biomarkers; Child; Child, Preschool; Databases,

2018
Adherence to Antipsychotic Adverse Effect Monitoring Among a Referred Sample of Children with Intellectual Disabilities.
    Journal of child and adolescent psychopharmacology, 2019, Volume: 29, Issue:3

    Topics: Adolescent; Antipsychotic Agents; Body Mass Index; Canada; Community Mental Health Services; Drug-Re

2019
Management of sexual adverse effects induced by atypical antipsychotic medication
    Journal of psychiatry & neuroscience : JPN, 2019, 07-01, Volume: 44, Issue:4

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Drug Substitution; Drug-Related Side Effects and Adverse

2019
Age and adverse drug reactions from psychopharmacological treatment: data from the AMSP drug surveillance programme in Switzerland.
    Swiss medical weekly, 2013, Volume: 143

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; An

2013
Decision making and antipsychotic medication treatment for youth with autism spectrum disorders: applying guidelines in the real world.
    The Journal of clinical psychiatry, 2013, Volume: 74, Issue:10

    Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Child; Child Development Disorders, Pervasive; Child

2013
Quality of Life and Hormonal, Biochemical, and Anthropometric Profile Between Olanzapine and Risperidone Users.
    The Psychiatric quarterly, 2016, Volume: 87, Issue:2

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Pressure; Body Weights and Measures; Cross-Secti

2016
Neurological Adverse Effects of Antipsychotics in Children and Adolescents.
    Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:6

    Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Child; Child, Preschool; Drug-Related Side Effect

2015
Comparing Efficacy and Side Effects of Memantine vs. Risperidone in the Treatment of Autistic Disorder.
    Pharmacopsychiatry, 2017, Volume: 50, Issue:1

    Topics: Autistic Disorder; Child; Child, Preschool; Dopamine Agents; Dose-Response Relationship, Drug; Drug-

2017
[Antipsychotic treatment of dementia after publication of new risks].
    Psychiatrische Praxis, 2010, Volume: 37, Issue:2

    Topics: Adverse Drug Reaction Reporting Systems; Aged; Alzheimer Disease; Antipsychotic Agents; Cerebral Inf

2010
Drug research: marketing before evidence, sales before safety.
    Deutsches Arzteblatt international, 2010, Volume: 107, Issue:16

    Topics: Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Conflict of Interest; Drug Industry

2010
Association of common genetic variants with risperidone adverse events in a Spanish schizophrenic population.
    The pharmacogenomics journal, 2013, Volume: 13, Issue:2

    Topics: Alleles; Drug-Related Side Effects and Adverse Reactions; Genetic Association Studies; Humans; Polym

2013
Differential risk of death in older residents in nursing homes prescribed specific antipsychotic drugs: population based cohort study.
    BMJ (Clinical research ed.), 2012, Feb-23, Volume: 344

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Cause of Death; Comorbidity; Dementia; Dibenzothiazep

2012
Quality of life and adverse effects of olanzapine versus risperidone therapy in patients with schizophrenia.
    The Psychiatric quarterly, 2013, Volume: 84, Issue:1

    Topics: Activities of Daily Living; Adult; Ambulatory Care; Antipsychotic Agents; Benzodiazepines; Brazil; C

2013
The switching of risperidone to olanzapine in elderly nursing-home patients with dementia: a retrospective study.
    CNS spectrums, 2007, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Benzodiazepines; Comorbidity; Dementia, Vascular; Dose-R

2007
[Why measure drug metabolites?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2007, Jun-28, Volume: 127, Issue:13

    Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Cyclohexanols; Cytochrome P-450 Enzy

2007
Post-marketing studies: the work of the Drug Safety Research Unit.
    Drug safety, 1998, Volume: 19, Issue:5

    Topics: Antipsychotic Agents; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Epidemiol

1998