Page last updated: 2024-11-03

risperidone and Drug Overdose

risperidone has been researched along with Drug Overdose in 31 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"Here is a case of a woman with schizophrenia who developed rhabdomyolysis following overdose of risperidone, trihexyphenidyl and benzodiazepines."7.80Multidrug overdose-induced myoclonus complicated by rhabdomyolysis: possible role and mechanism of muscle toxicity of risperidone. ( Hsu, YC; Yeh, YW, 2014)
"A 31-year-old patient suffering from schizophrenic psychosis was treated with risperidone, and developed priapism which required surgical intervention and resulted in long-term erectile dysfunction."7.74Risperidone-induced priapism. ( Makesar, D; Thome, J, 2007)
"BACKGROUND Serotonin syndrome is a condition characterized predominantly by neuromuscular symptoms and altered thermoregulation in response to serotonergic overtone."5.48Delayed Serotonin Syndrome in the Setting of a Mixed Fluoxetine and Serotonin Antagonist Overdose. ( Lin, CM; Little, K; Reynolds, PM, 2018)
"Deliberate drug overdose is a frequent occurrence in patients with schizophrenia."5.30A case of risperidone overdose in early schizophrenia: a review of potential complications. ( Day, C; Dillman, B; Gardner, D; Kopala, LC, 1998)
" In this preliminary report we describe 3 cases of patients with schizophrenia, who are treated with long-term injectable risperidone (Risperdal Consta) and were false positively screened for fentanyl by a rapid commercial screening kit."4.02False-positive fentanyl screening kit results during treatment with long term injectable risperidone (Risperdal-Consta). ( Even-Tov, S; Peles, E; Schreiber, S; Shroitman, NK; Tene, O, 2021)
"Here is a case of a woman with schizophrenia who developed rhabdomyolysis following overdose of risperidone, trihexyphenidyl and benzodiazepines."3.80Multidrug overdose-induced myoclonus complicated by rhabdomyolysis: possible role and mechanism of muscle toxicity of risperidone. ( Hsu, YC; Yeh, YW, 2014)
"A 31-year-old patient suffering from schizophrenic psychosis was treated with risperidone, and developed priapism which required surgical intervention and resulted in long-term erectile dysfunction."3.74Risperidone-induced priapism. ( Makesar, D; Thome, J, 2007)
" However, there are still significant adverse effects and toxicities with this class of medications."2.43Toxicology and overdose of atypical antipsychotic medications in children: does newer necessarily mean safer? ( Dubois, D, 2005)
"Risperidone is an atypical antipsychotic medication commonly used to treat psychotic illnesses in adults."2.41Atypical antipsychotic overdose in the pediatric population. ( Catalano, G; Catalano, MC; Nunez, CY; Walker, SC, 2001)
"Risperidone was the sole ingestant in 15 cases (1 mg to 180 mg)."2.40Effects of risperidone in overdose. ( Acri, AA; Henretig, FM, 1998)
"BACKGROUND Serotonin syndrome is a condition characterized predominantly by neuromuscular symptoms and altered thermoregulation in response to serotonergic overtone."1.48Delayed Serotonin Syndrome in the Setting of a Mixed Fluoxetine and Serotonin Antagonist Overdose. ( Lin, CM; Little, K; Reynolds, PM, 2018)
"Carbamazepine (CBZ) is an antiepileptic drug used as a mood stabilizer in child psychiatry."1.42[Carbamazepine and psychotropic treatment interaction: Two case studies of carbamazepine overdosage]. ( Askenazy, F; Dor, E; Fernandez, A; Menard, ML; Thümmler, S, 2015)
"Risperidone is an atypical antipsychotic drug used for the treatment of schizophrenia."1.33Delayed respiratory depression after risperidone overdose. ( Akyol, A; Erciyes, N; Karip, F; Senel, AC; Ulusoy, H, 2005)
"Both patients presented with fatigue, orthostasis, dry mucous membranes, and the unusual finding of miosis."1.31Atypical presentation of risperidone toxicity. ( Gummin, DD; Hodge, CH; Jewell, M; Leikin, JB, 2001)
"Risperidone (Risperdal) is a recently released novel antipsychotic medication."1.30Acute risperidone overdose. ( Catalano, G; Catalano, MC; Taylor, W, 1997)
"Deliberate drug overdose is a frequent occurrence in patients with schizophrenia."1.30A case of risperidone overdose in early schizophrenia: a review of potential complications. ( Day, C; Dillman, B; Gardner, D; Kopala, LC, 1998)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (19.35)18.2507
2000's15 (48.39)29.6817
2010's8 (25.81)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Shroitman, NK1
Peles, E1
Even-Tov, S1
Schreiber, S1
Tene, O1
Cooper, J3
Duffull, SB3
Isbister, GK5
Okada, Y1
Ishi, W1
Narumiya, H1
Liduka, R1
Little, K1
Lin, CM1
Reynolds, PM1
Hitosugi, M1
Tsukada, C1
Yamauchi, S1
Nagai, T1
Hsu, YC1
Yeh, YW1
Fernandez, A1
Dor, E1
Menard, ML1
Askenazy, F1
Thümmler, S1
Karaca, S1
Özatalay, E1
Canan, F1
Tan, HH1
Hoppe, J1
Heard, K1
Page, CB1
Calver, LA1
Pollak, PT1
Verjee, ZH1
Lyon, AW1
Rassam, S1
Srinivasa, R1
Raja, M1
Azzoni, A1
Camilleri, C1
Albertson, T1
Offerman, S1
Malik, AR1
Wolf, PK1
Ravasia, S1
Dubois, D1
Akyol, A1
Senel, AC1
Ulusoy, H1
Karip, F1
Erciyes, N1
Antia, SX1
Sholevar, EH1
Baron, DA1
Makesar, D1
Thome, J1
Rajkumar, AP1
Jebaraj, P1
Tharyan, P1
Lo Vecchio, F1
Hamilton, RJ1
Hoffman, RJ1
Cheslik, TA1
Erramouspe, J1
Moore, NC1
Shukla, P1
Catalano, G2
Catalano, MC2
Taylor, W1
Acri, AA1
Henretig, FM1
Kopala, LC1
Day, C1
Dillman, B1
Gardner, D1
Blanch, J1
Corbella, B1
García, F1
Parellada, E1
Gatell, JM1
Hodge, CH1
Jewell, M1
Gummin, DD1
Leikin, JB1
Nunez, CY1
Walker, SC1
Whyte, IM1
Titier, K1
Déridet, E1
Cardone, E1
Abouelfath, A1
Moore, N1

Reviews

4 reviews available for risperidone and Drug Overdose

ArticleYear
A systematic review of cardiovascular effects after atypical antipsychotic medication overdose.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:5

    Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Cardiovascular System; Dibenzothiazepines; Drug

2009
Toxicology and overdose of atypical antipsychotic medications in children: does newer necessarily mean safer?
    Current opinion in pediatrics, 2005, Volume: 17, Issue:2

    Topics: Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Benzodiazepines; Cardiomyopathies; Child

2005
Effects of risperidone in overdose.
    The American journal of emergency medicine, 1998, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Antipsychotic Agents; Child; Child, Preschool; Drug Overdose; Emergency Treatment

1998
Atypical antipsychotic overdose in the pediatric population.
    Journal of child and adolescent psychopharmacology, 2001,Winter, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Antipsychotic Agents; Child; Child, Preschool; Drug Overdose; Female; Humans; Mal

2001

Other Studies

27 other studies available for risperidone and Drug Overdose

ArticleYear
False-positive fentanyl screening kit results during treatment with long term injectable risperidone (Risperdal-Consta).
    Psychiatry research, 2021, Volume: 305

    Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Risperidone; Schizophrenia; United States

2021
Predicting serotonin toxicity in serotonin reuptake inhibitor overdose.
    Clinical toxicology (Philadelphia, Pa.), 2023, Volume: 61, Issue:1

    Topics: Adult; Drug Overdose; Female; Humans; Male; Moclobemide; Olanzapine; Retrospective Studies; Risperid

2023
Predicting serotonin toxicity in serotonin reuptake inhibitor overdose.
    Clinical toxicology (Philadelphia, Pa.), 2023, Volume: 61, Issue:1

    Topics: Adult; Drug Overdose; Female; Humans; Male; Moclobemide; Olanzapine; Retrospective Studies; Risperid

2023
Predicting serotonin toxicity in serotonin reuptake inhibitor overdose.
    Clinical toxicology (Philadelphia, Pa.), 2023, Volume: 61, Issue:1

    Topics: Adult; Drug Overdose; Female; Humans; Male; Moclobemide; Olanzapine; Retrospective Studies; Risperid

2023
Predicting serotonin toxicity in serotonin reuptake inhibitor overdose.
    Clinical toxicology (Philadelphia, Pa.), 2023, Volume: 61, Issue:1

    Topics: Adult; Drug Overdose; Female; Humans; Male; Moclobemide; Olanzapine; Retrospective Studies; Risperid

2023
Unexpected hypotension in catecholamine reversal: a case report.
    Journal of medical case reports, 2017, Oct-06, Volume: 11, Issue:1

    Topics: Adult; Antipsychotic Agents; Catecholamines; Drug Overdose; Humans; Hypotension; Male; Risperidone

2017
Delayed Serotonin Syndrome in the Setting of a Mixed Fluoxetine and Serotonin Antagonist Overdose.
    The American journal of case reports, 2018, May-25, Volume: 19

    Topics: Benzodiazepines; Bupropion; Cyproheptadine; Dopamine Uptake Inhibitors; Drug Overdose; Fluoxetine; H

2018
A case of fatal risperidone poisoning alerts physicians.
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:2

    Topics: Antipsychotic Agents; Drug Overdose; Female; Humans; Middle Aged; Risperidone

2014
Multidrug overdose-induced myoclonus complicated by rhabdomyolysis: possible role and mechanism of muscle toxicity of risperidone.
    Journal of clinical pharmacy and therapeutics, 2014, Volume: 39, Issue:6

    Topics: Antipsychotic Agents; Benzodiazepines; Drug Overdose; Female; Humans; Middle Aged; Myoclonus; Rhabdo

2014
[Carbamazepine and psychotropic treatment interaction: Two case studies of carbamazepine overdosage].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2015, Volume: 22, Issue:5

    Topics: Adolescent; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Overdose; Drug

2015
A Case of Risperidone Overdose in a 4-Year-Old Boy.
    The primary care companion for CNS disorders, 2016, Volume: 18, Issue:2

    Topics: Antipsychotic Agents; Child, Preschool; Drug Overdose; Humans; Male; Risperidone

2016
Risperidone overdose causes extrapyramidal effects but not cardiac toxicity.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Antipsychotic Agents; Basal Ganglia Diseases; Databases, Factual; Drug Overdose;

2010
Risperidone-induced QT prolongation following overdose correlates with serum drug concentration and resolves rapidly with no evidence of altered pharmacokinetics.
    Journal of clinical pharmacology, 2011, Volume: 51, Issue:7

    Topics: Adult; Affective Disorders, Psychotic; Antipsychotic Agents; Arrhythmias, Cardiac; Drug Overdose; Fe

2011
Respiratory depression after accidental risperidone overdose.
    The American journal of emergency medicine, 2002, Volume: 20, Issue:6

    Topics: Accidents; Aged; Antipsychotic Agents; Drug Overdose; Female; Humans; Respiratory Insufficiency; Ris

2002
Oxcarbazepine, risperidone and atenolol overdose with benign outcome.
    The international journal of neuropsychopharmacology, 2003, Volume: 6, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Alcoholism; Anticonvulsants; Antipsychotic Agents; Atenolol; Bip

2003
Fatal cerebral edema after moderate valproic acid overdose.
    Annals of emergency medicine, 2005, Volume: 45, Issue:3

    Topics: Adult; Ammonia; Brain Edema; Cyclohexanols; Drug Overdose; Fatal Outcome; Humans; Male; Risperidone;

2005
Hypokalemia from risperidone and quetiapine overdose.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2005, Volume: 50, Issue:1

    Topics: Adult; Antipsychotic Agents; Dibenzothiazepines; Drug Overdose; Humans; Hypokalemia; Male; Quetiapin

2005
Delayed respiratory depression after risperidone overdose.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:5

    Topics: Adult; Antipsychotic Agents; Drug Overdose; Female; Humans; Respiration; Risperidone; Time Factors

2005
Overdoses and ingestions of second-generation antipsychotics in children and adolescents.
    Journal of child and adolescent psychopharmacology, 2005, Volume: 15, Issue:6

    Topics: Adolescent; Antipsychotic Agents; Cause of Death; Child; Clozapine; Drug Overdose; Female; Humans; M

2005
Risperidone-induced priapism.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2007, Volume: 8, Issue:1

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Dose-Response Relationship, Drug; Drug Overdose; Erect

2007
Multi-drug overdose risperidone, ziprasidone, valproate, trihexyphenidyl, and clonazepam.
    The Journal of the Association of Physicians of India, 2007, Volume: 55

    Topics: Adult; Antipsychotic Agents; Clonazepam; Drug Overdose; Drug Prescriptions; Female; Humans; Piperazi

2007
Risperidone overdose.
    The American journal of emergency medicine, 1996, Volume: 14, Issue:1

    Topics: Adult; Antipsychotic Agents; Drug Overdose; Electrocardiography; Emergency Medical Services; Female;

1996
Extrapyramidal symptoms following accidental ingestion of risperidone in a child.
    The Annals of pharmacotherapy, 1996, Volume: 30, Issue:4

    Topics: Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Child, Preschool; Diphenhydramin

1996
Risperidone overdose.
    The American journal of psychiatry, 1997, Volume: 154, Issue:2

    Topics: Adult; Drug Overdose; Humans; Male; Risperidone; Schizophrenia; Suicide, Attempted

1997
Acute risperidone overdose.
    Clinical neuropharmacology, 1997, Volume: 20, Issue:1

    Topics: Adult; Antipsychotic Agents; Dopamine Antagonists; Drug Overdose; Humans; Male; Risperidone; Seroton

1997
A case of risperidone overdose in early schizophrenia: a review of potential complications.
    Journal of psychiatry & neuroscience : JPN, 1998, Volume: 23, Issue:5

    Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Drug Interactions; Drug Overd

1998
Manic syndrome associated with efavirenz overdose.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Jul-15, Volume: 33, Issue:2

    Topics: Adult; Alkynes; Anti-HIV Agents; Antipsychotic Agents; Benzoxazines; Bipolar Disorder; Cyclopropanes

2001
Atypical presentation of risperidone toxicity.
    Veterinary and human toxicology, 2001, Volume: 43, Issue:6

    Topics: Administration, Oral; Adolescent; Antipsychotic Agents; Diagnosis, Differential; Dizziness; Drug Ove

2001
Atypical presentation of risperidone toxicity.
    Veterinary and human toxicology, 2002, Volume: 44, Issue:2

    Topics: Adult; Antipsychotic Agents; Diagnosis, Differential; Drug Overdose; Female; Humans; Male; Miosis; R

2002
Simplified high-performance liquid chromatographic method for determination of risperidone and 9-hydroxyrisperidone in plasma after overdose.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002, Jun-05, Volume: 772, Issue:2

    Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Drug Overdose; Humans; Isoxazoles; Palip

2002