Page last updated: 2024-11-03

risperidone and Disease Exacerbation

risperidone has been researched along with Disease Exacerbation in 22 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Research Excerpts

ExcerptRelevanceReference
"A 39-year-old man with schizophrenia developed severe catatonia, hyperthermia, muscle rigidity, tachycardia, leukocytosis, and elevated muscle enzyme levels while receiving zotepine therapy."7.73Zotepine-induced catatonia as a precursor in the progression to neuroleptic malignant syndrome. ( Chen, CC; Tsai, JH; Yang, MJ; Yang, P; Yen, JY, 2005)
"A 39-year-old man with schizophrenia developed severe catatonia, hyperthermia, muscle rigidity, tachycardia, leukocytosis, and elevated muscle enzyme levels while receiving zotepine therapy."3.73Zotepine-induced catatonia as a precursor in the progression to neuroleptic malignant syndrome. ( Chen, CC; Tsai, JH; Yang, MJ; Yang, P; Yen, JY, 2005)
"CATIE-AD included 421 outpatients with Alzheimer's disease and psychosis or agitated/aggressive behavior who were randomly assigned to receive masked, flexible-dose olanzapine, quetiapine, risperidone, or placebo."2.76Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-AD. ( Dagerman, KS; Hsiao, JK; Keefe, RS; Lebowitz, BD; Lyketsos, CG; Mack, WJ; Sano, M; Schneider, LS; Stroup, TS; Sultzer, DL; Tariot, PN; Vigen, CL; Zheng, L, 2011)
"Hallucinations and psychosis are common in patients with Parkinson's disease (PD), with reported prevalences of up to 48% and 80%, respectively."2.46Management of hallucinations and psychosis in Parkinson's disease. ( Eng, ML; Welty, TE, 2010)
"Once the clinical diagnosis of Alzheimer's disease has been made, a treatment plan must be developed."2.41Guidelines for managing Alzheimer's disease: Part II. Treatment. ( Cherry, D; Cummings, JL; Frank, JC; Hewett, L; Kemp, B; Kohatsu, ND; Mittman, B, 2002)
"The increasing recognition of Tourette's syndrome is probably responsible for the broadening range of symptom severities seen in clinic patients."2.39Considerations of natural history and pathophysiology in the psychopharmacology of Tourette's syndrome. ( Peterson, BS, 1996)
"UHDRS (Unified Huntington's Disease Rating Scale) motor scores were obtained from medical records as an index of disease progression."1.42Examining Huntington's disease patient and informant concordance on frontally mediated behaviors. ( Cimino, CR; Hergert, DC; Sanchez-Ramos, J, 2015)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (18.18)18.2507
2000's9 (40.91)29.6817
2010's8 (36.36)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Rojo-Moreno, J1
Rojo-Valdemoro, C1
Santolaya-Ochando, F1
Carlone, D1
Delva, N1
Dal Mas, C1
Nani, JV1
Noto, C1
Yonamine, CM1
da Cunha, GR1
Mansur, RB1
Ota, VK1
Belangero, SI1
Cordeiro, Q1
Kapczinski, F1
Brietzke, E1
Bressan, RA1
Gadelha, A1
Hayashi, MAF1
Molina, V1
Taboada, D1
Aragüés, M1
Hernández, JA1
Sanz-Fuentenebro, J1
Kazdal, H1
Kanat, A1
Sen, A1
Kirbas, S1
Ardic, G1
Tufekci, A1
Ersoz, T1
Hergert, DC1
Sanchez-Ramos, J1
Cimino, CR1
Takahashi, T1
Wood, SJ1
Yung, AR2
Soulsby, B1
McGorry, PD3
Suzuki, M1
Kawasaki, Y1
Phillips, LJ2
Velakoulis, D1
Pantelis, C1
Chittiprol, S1
Venkatasubramanian, G1
Neelakantachar, N1
Reddy, NA1
Shetty, KT1
Gangadhar, BN1
Eng, ML1
Welty, TE1
Vigen, CL1
Mack, WJ1
Keefe, RS1
Sano, M1
Sultzer, DL1
Stroup, TS1
Dagerman, KS1
Hsiao, JK1
Lebowitz, BD1
Lyketsos, CG1
Tariot, PN1
Zheng, L1
Schneider, LS1
Schennach, R1
Riesbeck, M1
Mayr, A1
Seemüller, F1
Maier, W1
Klingberg, S1
Heuser, I1
Klosterkötter, J1
Gastpar, M1
Schmitt, A1
Sauer, H1
Schneider, F1
Jäger, M1
Wölwer, W1
Gaebel, W1
Möller, HJ1
Riedel, M1
Yuen, HP1
Francey, S1
Cosgrave, EM1
Germano, D1
Bravin, J1
McDonald, T1
Blair, A1
Adlard, S1
Jackson, H1
Kafantaris, V1
Coletti, DJ1
Dicker, R1
Padula, G1
Pleak, RR1
Alvir, JM1
Lambert, M1
Conus, P1
Lubman, DI1
Wade, D1
Yuen, H1
Moritz, S1
Naber, D1
Schimmelmann, BG1
Tsai, JH1
Yang, P1
Yen, JY1
Chen, CC1
Yang, MJ1
Wu, PL1
Lane, HY1
Su, KP1
Singh, D1
Forlano, R1
Athey, R1
Peterson, BS1
Meco, G1
Alessandri, A1
Giustini, P1
Bonifati, V1
Waddington, JL1
Scully, PJ1
O'Callaghan, E1
Volavka, J1
Citrome, L1
Cummings, JL1
Frank, JC1
Cherry, D1
Kohatsu, ND1
Kemp, B1
Hewett, L1
Mittman, B1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Real-world Effectiveness and Safety of Antipsychotics in Individuals at Clinical High-risk for Psychosis: Study Protocol for a Prospective Observational Study (SHARP-2)[NCT04010864]600 participants (Anticipated)Observational [Patient Registry]2019-03-29Recruiting
CLUES (Cognition for Learning and for Understanding Everyday Social Situations): An Adaptation of Cognitive Enhancement Therapy for Persons at Clinical High Risk for Psychosis[NCT02459210]58 participants (Actual)Interventional2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for risperidone and Disease Exacerbation

ArticleYear
Management of hallucinations and psychosis in Parkinson's disease.
    The American journal of geriatric pharmacotherapy, 2010, Volume: 8, Issue:4

    Topics: Aged; Antipsychotic Agents; Brief Psychiatric Rating Scale; Clozapine; Comorbidity; Delusions; Demen

2010
Considerations of natural history and pathophysiology in the psychopharmacology of Tourette's syndrome.
    The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 9

    Topics: Adolescent; Adult; Age of Onset; Antipsychotic Agents; Child; Clozapine; Disease Progression; Diseas

1996
Atypical antipsychotics in the treatment of the persistently aggressive psychotic patient: methodological concerns.
    Schizophrenia research, 1999, Mar-01, Volume: 35 Suppl

    Topics: Aggression; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Disease Progressio

1999
Guidelines for managing Alzheimer's disease: Part II. Treatment.
    American family physician, 2002, Jun-15, Volume: 65, Issue:12

    Topics: Advance Directives; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Disease Progression; D

2002

Trials

6 trials available for risperidone and Disease Exacerbation

ArticleYear
Progressive gray matter reduction of the superior temporal gyrus during transition to psychosis.
    Archives of general psychiatry, 2009, Volume: 66, Issue:4

    Topics: Adolescent; Adult; Antipsychotic Agents; Atrophy; Bipolar Disorder; Cognitive Behavioral Therapy; Co

2009
Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-AD.
    The American journal of psychiatry, 2011, Volume: 168, Issue:8

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Benzod

2011
Should early improvement be re-defined to better predict the maintenance of response in first-episode schizophrenia patients?
    Acta psychiatrica Scandinavica, 2013, Volume: 127, Issue:6

    Topics: Adult; Antipsychotic Agents; Disease Progression; Double-Blind Method; Female; Haloperidol; Humans;

2013
Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms.
    Archives of general psychiatry, 2002, Volume: 59, Issue:10

    Topics: Adolescent; Adult; Antipsychotic Agents; Australia; Cognitive Behavioral Therapy; Combined Modality

2002
Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms.
    Archives of general psychiatry, 2002, Volume: 59, Issue:10

    Topics: Adolescent; Adult; Antipsychotic Agents; Australia; Cognitive Behavioral Therapy; Combined Modality

2002
Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms.
    Archives of general psychiatry, 2002, Volume: 59, Issue:10

    Topics: Adolescent; Adult; Antipsychotic Agents; Australia; Cognitive Behavioral Therapy; Combined Modality

2002
Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms.
    Archives of general psychiatry, 2002, Volume: 59, Issue:10

    Topics: Adolescent; Adult; Antipsychotic Agents; Australia; Cognitive Behavioral Therapy; Combined Modality

2002
Lithium treatment of acute mania in adolescents: a placebo-controlled discontinuation study.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2004, Volume: 43, Issue:8

    Topics: Acute Disease; Adolescent; Aggression; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Bri

2004
Risperidone in levodopa-induced psychosis in advanced Parkinson's disease: an open-label, long-term study.
    Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:4

    Topics: Aged; Antipsychotic Agents; Disease Progression; Female; Follow-Up Studies; Humans; Levodopa; Male;

1997

Other Studies

12 other studies available for risperidone and Disease Exacerbation

ArticleYear
Royal Eschizophilia. Genealogical delusion or Mignon delusion as a pathoplastic realization.
    Actas espanolas de psiquiatria, 2019, Volume: 47, Issue:6

    Topics: Age Factors; Antipsychotic Agents; Carbamazepine; Delusions; Disease Progression; Fellowships and Sc

2019
Long-acting injectable antipsychotics: choosing the right dose.
    Journal of psychiatry & neuroscience : JPN, 2020, 07-01, Volume: 45, Issue:4

    Topics: Antipsychotic Agents; Delayed-Action Preparations; Disease Progression; Drug Substitution; Humans; I

2020
Ndel1 oligopeptidase activity as a potential biomarker of early stages of schizophrenia.
    Schizophrenia research, 2019, Volume: 208

    Topics: Adolescent; Adult; Antipsychotic Agents; Biomarkers; Carrier Proteins; Cohort Studies; Disease Progr

2019
Greater clinical and cognitive improvement with clozapine and risperidone associated with a thinner cortex at baseline in first-episode schizophrenia.
    Schizophrenia research, 2014, Volume: 158, Issue:1-3

    Topics: Adult; Antipsychotic Agents; Clozapine; Cognition Disorders; Disease Progression; Female; Follow-Up

2014
A novel clinical observation in neuroleptic malignant-like syndrome: first demonstration of early progression of hydrocephalus.
    Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:2

    Topics: Aged; Antipsychotic Agents; Depressive Disorder, Major; Disease Progression; Fatal Outcome; Female;

2015
Examining Huntington's disease patient and informant concordance on frontally mediated behaviors.
    Journal of clinical and experimental neuropsychology, 2015, Volume: 37, Issue:9

    Topics: Adult; Aged; Antipsychotic Agents; Awareness; Cognition Disorders; Disease Progression; Female; Fron

2015
Longitudinal study of beta2-microglobulin abnormalities in schizophrenia.
    International immunopharmacology, 2009, Volume: 9, Issue:10

    Topics: Adult; Antipsychotic Agents; beta 2-Microglobulin; Disease Progression; Female; Follow-Up Studies; H

2009
The impact of substance use disorders on clinical outcome in 643 patients with first-episode psychosis.
    Acta psychiatrica Scandinavica, 2005, Volume: 112, Issue:2

    Topics: Adult; Antipsychotic Agents; Australia; Benzodiazepines; Cohort Studies; Disease Progression; Female

2005
Zotepine-induced catatonia as a precursor in the progression to neuroleptic malignant syndrome.
    Pharmacotherapy, 2005, Volume: 25, Issue:8

    Topics: Antipsychotic Agents; Blood Chemical Analysis; Catatonia; Dibenzothiepins; Disease Progression; Feve

2005
Risperidone alternative for a schizophrenic patient with olanzapine-exacerbated diabetic mellitus.
    Psychiatry and clinical neurosciences, 2006, Volume: 60, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Diabetes Mellitus, Type 2; Disease Progression; Humans

2006
Neuroleptic malignant syndrome and catatonia in a patient with dementia.
    The Australian and New Zealand journal of psychiatry, 2008, Volume: 42, Issue:6

    Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Catatonia; Chlorpromazine; Choline

2008
The new antipsychotics, and their potential for early intervention in schizophrenia.
    Schizophrenia research, 1997, Dec-19, Volume: 28, Issue:2-3

    Topics: Antipsychotic Agents; Clozapine; Disease Progression; Dopamine Antagonists; Humans; Risperidone; Sch

1997