Page last updated: 2024-11-03

risperidone and Depression, Involutional

risperidone has been researched along with Depression, Involutional in 76 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.

Research Excerpts

ExcerptRelevanceReference
"The present findings suggest that clozapine demonstrates superior antidepressant effects to quetiapine and comparable effects to olanzapine and risperidone in chronic schizophrenia regardless of presence of MDE."9.20Comparative efficacy between clozapine and other atypical antipsychotics on depressive symptoms in patients with schizophrenia: analysis of the CATIE phase 2E data. ( Caravaggio, F; Chung, JK; Fervaha, G; Gerretsen, P; Graff-Guerrero, A; Iwata, Y; Mihashi, Y; Mulsant, B; Nakajima, S; Plitman, E; Remington, G; Takeuchi, H, 2015)
"Antipsychotic drugs plus aspirin (acetylsalicylic acid), which targets prostaglandin-endoperoxide synthase 1 (PTGS1: COX1), improved therapeutic outcomes when treating schizophrenia."7.88Studies on Prostaglandin-Endoperoxide Synthase 1: Lower Levels in Schizophrenia and After Treatment with Antipsychotic Drugs in Conjunction with Aspirin. ( Dean, B; Gibbons, A; Gogos, A; Scarr, E; Thomas, E; Udawela, M, 2018)
"The aim of this study was to compare the treatment effectiveness between long-acting injectable risperidone and long-acting injectable first-generation antipsychotics among patients with bipolar disorder."7.83Comparative effectiveness of long-acting injectable risperidone vs. long-acting injectable first-generation antipsychotics in bipolar disorder. ( Chang, CJ; Hsieh, MH; Tang, CH; Wu, CS, 2016)
"Prolactin levels returned to normal, and clinical symptoms of hyperprolactinemia resolved in all 3 patients after 2 weeks of tapering and discontinuation of risperidone."7.73Risperidone-induced hyperprolactinemia in adolescents: A case series. ( Madhusoodanan, S; Moise, D, 2006)
"MDD and dysphoria commonly occurred in this cohort of adult and adolescent Tourette's disorder patients treated with risperidone, particularly in patients with a previous history of depression."7.71Depression and dysphoria in adult and adolescent patients with Tourette's disorder treated with risperidone. ( Annable, L; Dion, Y; Margolese, HC, 2002)
"Medicamentous hyperprolactinaemia is a well known side effect of risperidone."5.36Hyperprolactinaemia - a risperidone side-effect. ( Dadić-Hero, E; Grahovac, T; Medved, P; Pavesić-Radonja, A; Ruzić, K, 2010)
"To assess the benefit of short-term treatment with the atypical antipsychotic asenapine versus placebo on depressive symptoms in patients with acute schizophrenia in an exacerbated state."5.20Management of depressive symptoms in schizophrenia. ( Castle, DJ; Slott Jensen, JK, 2015)
"The present findings suggest that clozapine demonstrates superior antidepressant effects to quetiapine and comparable effects to olanzapine and risperidone in chronic schizophrenia regardless of presence of MDE."5.20Comparative efficacy between clozapine and other atypical antipsychotics on depressive symptoms in patients with schizophrenia: analysis of the CATIE phase 2E data. ( Caravaggio, F; Chung, JK; Fervaha, G; Gerretsen, P; Graff-Guerrero, A; Iwata, Y; Mihashi, Y; Mulsant, B; Nakajima, S; Plitman, E; Remington, G; Takeuchi, H, 2015)
"Forty-eight patients with remitted DSM-IV schizophrenia and comorbid major depression were randomized to placebo for 6 weeks or sertraline 50 mg for 4 weeks followed by sertraline 50 mg to 100 mg for 2 weeks for nonresponders."5.12Serum monitoring of antipsychotic drug levels during concomitant administration of sertraline and antipsychotic medication. ( Addington, D; Addington, J; Patten, S; Pierson, K, 2006)
"The Treatment of Early Onset Schizophrenia Spectrum Disorders Study is a publicly funded clinical trial designed to compare the therapeutic benefits, safety, and tolerability of risperidone, olanzapine, and molindone in youths with early-onset schizophrenia spectrum disorders."5.12Treatment of early-onset schizophrenia spectrum disorders (TEOSS): rationale, design, and methods. ( Ambler, D; Anderson, R; Findling, RL; Frazier, JA; Hamer, RM; Hlastala, SA; Hunt-Harrison, T; Lieberman, JA; Maloney, AE; McCLELLAN, J; Ritz, L; Sikich, L; Vitiello, B; Williams, E, 2007)
"There is some evidence that in the short term risperidone may reduce aggression and conduct problems in children and youths with disruptive behaviour disorders There is also evidence that this intervention is associated with significant weight gain."4.95Atypical antipsychotics for disruptive behaviour disorders in children and youths. ( Hetrick, SE; Loy, JH; Merry, SN; Stasiak, K, 2017)
"There is some limited evidence of efficacy of risperidone reducing aggression and conduct problems in children aged 5 to 18 with disruptive behaviour disorders in the short term."4.88Atypical antipsychotics for disruptive behaviour disorders in children and youths. ( Hetrick, SE; Loy, JH; Merry, SN; Stasiak, K, 2012)
"Antipsychotic drugs plus aspirin (acetylsalicylic acid), which targets prostaglandin-endoperoxide synthase 1 (PTGS1: COX1), improved therapeutic outcomes when treating schizophrenia."3.88Studies on Prostaglandin-Endoperoxide Synthase 1: Lower Levels in Schizophrenia and After Treatment with Antipsychotic Drugs in Conjunction with Aspirin. ( Dean, B; Gibbons, A; Gogos, A; Scarr, E; Thomas, E; Udawela, M, 2018)
"The aim of this study was to compare the treatment effectiveness between long-acting injectable risperidone and long-acting injectable first-generation antipsychotics among patients with bipolar disorder."3.83Comparative effectiveness of long-acting injectable risperidone vs. long-acting injectable first-generation antipsychotics in bipolar disorder. ( Chang, CJ; Hsieh, MH; Tang, CH; Wu, CS, 2016)
"To identify the factors associated with newly prescribed, first-line, second-generation antipsychotics (SgAs) associated with weight gain-olanzapine, risperidone, and quetiapine."3.77Factors associated with the prescribing of olanzapine, quetiapine, and risperidone in patients with bipolar and related affective disorders. ( Arndt, S; Chrischilles, EA; Coryell, WH; Ellingrod, VL; Fiedorowicz, JG; Haynes, WG; Miller, del D; Prabhakar, M; Warren, L, 2011)
"Prolactin levels returned to normal, and clinical symptoms of hyperprolactinemia resolved in all 3 patients after 2 weeks of tapering and discontinuation of risperidone."3.73Risperidone-induced hyperprolactinemia in adolescents: A case series. ( Madhusoodanan, S; Moise, D, 2006)
"MDD and dysphoria commonly occurred in this cohort of adult and adolescent Tourette's disorder patients treated with risperidone, particularly in patients with a previous history of depression."3.71Depression and dysphoria in adult and adolescent patients with Tourette's disorder treated with risperidone. ( Annable, L; Dion, Y; Margolese, HC, 2002)
"Antipsychotics are widely used in the treatment of major depressive disorder (MDD), but there has been no comprehensive meta-analytic assessment that examined their use as monotherapy and adjunctive therapy."3.01Efficacy and safety/tolerability of antipsychotics in the treatment of adult patients with major depressive disorder: a systematic review and meta-analysis. ( Correll, CU; Hagi, K; Kane, JM; Kishimoto, T; Kurokawa, S, 2023)
"Pharmacological treatment of major depressive disorder is often inefficient, and multiple strategies are used for inadequate response to antidepressants."2.82Efficacy and acceptability of second-generation antipsychotics with antidepressants in unipolar depression augmentation: a systematic review and network meta-analysis. ( Chen, B; Ma, X; Wang, M; Yan, Y; Yang, X; Yin, L, 2022)
" Data were derived from an earlier study, designed to compare efficacy and tolerability of fixed dosage of extended-release venlafaxine, mitazapine, paroxetine, and risperidone, sodium valproate, buspirone, trazodone or thyroid hormone augmenting to paroxetine in those patients."2.78Difference in remission in a Chinese population with anxious versus nonanxious treatment-resistant depression: a report of OPERATION study. ( Cao, L; Chen, J; Fang, Y; Hong, W; Peng, D; Wu, Z; Yuan, C; Zhang, C, 2013)
" There was no statistical significance among treatment arms in remission rates, secondary outcome measures, and adverse events."2.76A pilot study of the efficacy and safety of paroxetine augmented with risperidone, valproate, buspirone, trazodone, or thyroid hormone in adult Chinese patients with treatment-resistant major depression. ( Calabrese, JR; Cao, L; Chen, J; Cui, X; Fang, Y; Gao, K; Hong, W; Jiang, K; Wang, Y; Wu, Z; Xu, Y; Yi, Z; Yuan, C, 2011)
"274 outpatient adults with major depressive disorder that was suboptimally responsive to antidepressant therapy."2.73Risperidone for treatment-refractory major depressive disorder: a randomized trial. ( Canuso, CM; Gharabawi-Garibaldi, GM; Kosik-Gonzalez, C; Kujawa, MJ; Mahmoud, RA; Pandina, GJ; Turkoz, I, 2007)
"Risperidone is an atypical antipsychotic drug with combined dopamine-2/serotonin-2 (D(2)/5-HT(2)) antagonist activity that has been effective in reducing cocaine use in some animal studies."2.73A randomized, double-blind, placebo-controlled trial of long-acting risperidone in cocaine-dependent men. ( Angarita, GA; Culhane, MA; Evins, AE; Huang, KL; Lee, SH; Loebl, T; Logvinenko, T; Nino, J; Pachas, GN, 2008)
"Risperidone is an atypical antipsychotic that displays antidepressant properties due to its activity at various serotonergic and dopaminergic receptors."2.47Use of risperidone as augmentation treatment for major depressive disorder. ( Brown, JN; Brown, LT; Owenby, RK, 2011)
"In risperidone-treated boys, SSRI use is associated with reduced longitudinal growth, particularly in those undergoing puberty."1.48Selective Serotonin Reuptake Inhibitors Reduce Longitudinal Growth in Risperidone-Treated Boys. ( Calarge, CA; Garcia, JM; Karaviti, L; Mills, JA; Teixeira, AL; Zemel, BS, 2018)
"Risperidone monotherapy was the primary antipsychotic treatment."1.43Antipsychotic pharmacogenomics in first episode psychosis: a role for glutamate genes. ( Badner, JA; Bishop, JR; Harris, MS; Keshavan, MS; Nimgaonkar, VL; Patel, SR; Prasad, KM; Reilly, JL; Stevenson, JM; Sweeney, JA; Weiden, PJ, 2016)
" "Instead of the medicament prescribed, a GP doctor is allowed to prescribe an alternative medicament of the same efficacy in the dosage of an adequate strength" (taken from the specialist medical report form)."1.36Side-effects of generic. ( Dadić-Hero, E; Graovac, M; Grzeta, IR; Medved, P; Ruzić, K; Tatalović-Vorkapić, S, 2010)
"Medicamentous hyperprolactinaemia is a well known side effect of risperidone."1.36Hyperprolactinaemia - a risperidone side-effect. ( Dadić-Hero, E; Grahovac, T; Medved, P; Pavesić-Radonja, A; Ruzić, K, 2010)
" However, no correlation between prolactin levels and dosage could be found."1.32[Plasma prolactin level and incidence of adverse endocrinologic effects during therapy with atypical neuroleptics]. ( Fric, M; Laux, G, 2003)
"Converging evidence indicates that, in controlled drug trials, individuals receiving novel antipsychotic medications have fewer adverse effects than those receiving conventional antipsychotic medications."1.31Short report: comparison of patient satisfaction and burden of adverse effects with novel and conventional neuroleptics: a naturalistic study. ( Bromet, EJ; Davidson, M; Rabinowitz, J, 2001)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's40 (52.63)29.6817
2010's30 (39.47)24.3611
2020's6 (7.89)2.80

Authors

AuthorsStudies
Li, Z2
Cai, G1
Fang, F1
Li, W1
Fan, M1
Lian, J1
Qiu, Y1
Xu, X1
Lv, X1
Li, Y1
Zheng, R1
Wang, Y2
Zhang, G1
Liu, Z1
Huang, Z1
Zhang, L1
Kishimoto, T1
Hagi, K1
Kurokawa, S1
Kane, JM1
Correll, CU1
Scott, F1
Hampsey, E1
Gnanapragasam, S1
Carter, B1
Marwood, L1
Taylor, RW1
Emre, C1
Korotkova, L1
Martín-Dombrowski, J1
Cleare, AJ1
Young, AH1
Strawbridge, R1
Yan, Y1
Yang, X1
Wang, M1
Chen, B1
Yin, L1
Ma, X1
Maximo, JO1
Nelson, EA1
Armstrong, WP1
Kraguljac, NV1
Lahti, AC1
Ou, H1
Chang, HA1
Kao, YC1
Tzeng, NS1
Loy, JH2
Merry, SN2
Hetrick, SE2
Stasiak, K2
Nesvåg, R1
Bramness, JG1
Handal, M1
Hartz, I1
Hjellvik, V1
Skurtveit, S1
Calarge, CA1
Mills, JA1
Karaviti, L1
Teixeira, AL1
Zemel, BS1
Garcia, JM1
Dean, B1
Gibbons, A1
Gogos, A1
Udawela, M1
Thomas, E1
Scarr, E1
Dias Alves, M1
Micoulaud-Franchi, JA1
Simon, N1
Vion-Dury, J1
Wu, Z2
Chen, J3
Yuan, C2
Hong, W2
Peng, D1
Zhang, C1
Cao, L2
Fang, Y2
Pandina, G1
Turkoz, I3
Bossie, C1
Wen, XJ1
Wang, LM1
Liu, ZL1
Huang, A1
Liu, YY1
Hu, JY1
Makkos, Z1
Lin, CY1
Tsai, GE1
Wang, HS1
Wu, YH1
Chiou, CC1
Wu, VY1
Lane, HY1
Castle, DJ1
Slott Jensen, JK1
Pietrzak, RH1
Rosenheck, RA1
Cramer, JA1
Vessichio, JC1
Tsai, J1
Southwick, SM1
Krystal, JH1
Nakajima, S1
Takeuchi, H1
Fervaha, G1
Plitman, E1
Chung, JK1
Caravaggio, F1
Iwata, Y1
Mihashi, Y1
Gerretsen, P1
Remington, G1
Mulsant, B1
Graff-Guerrero, A1
Kazdal, H1
Kanat, A1
Sen, A1
Kirbas, S1
Ardic, G1
Tufekci, A1
Ersoz, T1
Cawkwell, P1
Lawler, A1
Maneta, E1
Coffey, BJ1
Stevenson, JM1
Reilly, JL1
Harris, MS1
Patel, SR1
Weiden, PJ1
Prasad, KM1
Badner, JA1
Nimgaonkar, VL1
Keshavan, MS1
Sweeney, JA1
Bishop, JR1
Wu, CS1
Hsieh, MH1
Tang, CH1
Chang, CJ1
Ryan, PB1
Schuemie, MJ1
Ramcharran, D1
Stang, PE1
Laenger, A1
Leicht, G1
Schule, C1
Baghai, TC1
Lindhaus, S1
Rupprecht, R1
Keitner, GI1
Garlow, SJ1
Ryan, CE1
Ninan, PT1
Solomon, DA1
Nemeroff, CB1
Keller, MB1
Reeves, H1
Batra, S1
May, RS1
Zhang, R1
Dahl, DC1
Li, X1
Yoshimura, R1
Umene-Nakano, W1
Ueda, N1
Ikenouchi-Sugita, A1
Hori, H1
Nakamura, J1
Pandina, GJ2
Revicki, DA1
Kleinman, L1
Wu, JH1
Kujawa, MJ2
Mahmoud, R1
Gharabawi, GM1
Takahashi, T1
Wood, SJ1
Yung, AR1
Soulsby, B1
McGorry, PD1
Suzuki, M1
Kawasaki, Y1
Phillips, LJ1
Velakoulis, D1
Pantelis, C1
Benazzi, F1
Berk, M1
Frye, MA1
Wang, W1
Barraco, A1
Tohen, M1
Ruzić, K2
Medved, P2
Dadić-Hero, E2
Graovac, M1
Tatalović-Vorkapić, S1
Grzeta, IR1
Grahovac, T1
Pavesić-Radonja, A1
Gao, K2
Kemp, DE1
Komossa, K1
Depping, AM1
Gaudchau, A1
Kissling, W1
Leucht, S1
Owenby, RK1
Brown, LT1
Brown, JN1
Baez, MA1
Avery, J1
Xu, Y1
Yi, Z1
Jiang, K1
Cui, X1
Calabrese, JR2
Prabhakar, M1
Haynes, WG1
Coryell, WH1
Chrischilles, EA1
Miller, del D1
Arndt, S1
Ellingrod, VL1
Warren, L1
Fiedorowicz, JG1
Rapinesi, C1
Serata, D1
Del Casale, A1
Kotzalidis, GD2
Romano, S1
Milioni, M1
Capezzuto, S1
Carbonetti, P1
Angeletti, G1
Fensore, C1
Tatarelli, R2
Girardi, P2
Morag, A1
Oved, K1
Gurwitz, D1
Margolese, HC1
Annable, L1
Dion, Y1
Gupta, SC1
Jagadheesan, K1
Basu, S1
Paul, SE1
Fric, M1
Laux, G1
Tani, K1
Takei, N1
Kawai, M1
Suzuki, K1
Sekine, Y1
Toyoda, T1
Minabe, Y1
Mori, N1
Eren, I1
Ozcankaya, R1
Altinyazar, V1
Segal, J1
Szabo, CP1
du Toit, J1
Rachid, F1
Bertschy, G1
Bondolfi, G1
Aubry, JM1
Galynker, I1
Khan, A1
Grebchenko, Y1
Ten, A1
Malaya, L1
Yanowitch, P1
Cohen, LJ1
Marazziti, D1
Dell'Osso, B1
Del Tacca, M1
Lattanzi, L1
Lastella, M1
Di Paolo, A1
Mungai, F1
Danesi, R1
Menichetti, F1
Dell'osso, L1
Cassano, GB1
Deberdt, WG1
Dysken, MW1
Rappaport, SA1
Feldman, PD1
Young, CA1
Hay, DP1
Lehman, DL1
Dossenbach, M1
Degenhardt, EK1
Breier, A1
Manfredi, G1
Lazanio, S1
Ruberto, A1
Kozian, R1
Goldman, S1
Nierenberg, AA1
Ostacher, MJ1
Ketter, TA1
Marangell, LB1
Miklowitz, DJ1
Miyahara, S1
Bauer, MS1
Thase, ME1
Wisniewski, SR1
Sachs, GS1
Rasmussen, K1
Zink, M1
Knopf, U2
Argiriou, S1
Kuwilsky, A1
Madhusoodanan, S2
Moise, D1
Gabriel, A1
Pierson, K1
Addington, D1
Addington, J1
Patten, S1
McCLELLAN, J1
Sikich, L1
Findling, RL1
Frazier, JA1
Vitiello, B1
Hlastala, SA1
Williams, E1
Ambler, D1
Hunt-Harrison, T1
Maloney, AE1
Ritz, L1
Anderson, R1
Hamer, RM1
Lieberman, JA1
Marchesi, C1
Tonna, M1
Maggini, C1
Mahmoud, RA1
Kosik-Gonzalez, C1
Canuso, CM1
Gharabawi-Garibaldi, GM1
Philip, NS1
Carpenter, LL1
Tyrka, AR1
Price, LH1
Loebl, T1
Angarita, GA1
Pachas, GN1
Huang, KL1
Lee, SH1
Nino, J1
Logvinenko, T1
Culhane, MA1
Evins, AE1
Gupta, S1
Frank, B1
Hubrich-Ungureanu, P1
Thome, J1
Rubin, NJ1
Arceneaux, JM1
Weizman, R1
Weizman, A1
Rabinowitz, J1
Bromet, EJ1
Davidson, M1
Freudenreich, O1
Hoy, JS1
Alexander, B1

Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Glutamate, Brain Connectivity and Duration of Untreated Psychosis[NCT02034253]134 participants (Actual)Observational2014-01-31Completed
Trajectories of Treatment Response as Window Into the Heterogeneity of Psychosis: a Longitudinal Multimodal Imaging Study in Medication-naïve First Episode Psychosis Patients[NCT03442101]156 participants (Anticipated)Observational2018-04-01Recruiting
Neuroimaging Biomarker-Guided Personalized Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Major Depressive Episode in Adolescents and Young Adults With Mood Disorders: A Randomized, Double-Blind, Controlled Study[NCT05465928]120 participants (Anticipated)Interventional2022-08-01Recruiting
A Double-Blind Study Comparing Adjunctive Risperidone Versus Placebo in Major Depressive Disorder That Is Not Responding to Standard Therapy[NCT00095134]Phase 3630 participants (Actual)Interventional2004-10-31Completed
A Multicenter, Randomized, Double-Blind, Fixed-Dose, 6-Week Trial of the Efficacy and Safety of Asenapine Compared With Placebo Using Olanzapine Positive Control in Subjects With an Acute Exacerbation of Schizophrenia[NCT00156117]Phase 3417 participants (Actual)Interventional2005-05-12Completed
A Multicenter, Randomized, Double-Blind, Fixed-Dose, 6-Week Trial of the Efficacy and Safety of Asenapine Compared With Placebo Using Haloperidol Positive Control in Subjects With an Acute Exacerbation of Schizophrenia[NCT00156104]Phase 3460 participants (Actual)Interventional2005-07-01Completed
Efficacy of Risperidone in the Management of Suicidality in Major Depressive Disorder[NCT00167154]Phase 330 participants (Actual)Interventional2004-06-30Completed
Bipolar Disorder and Oxidative Stress Injury Mechanism - Clinical Big Data Analysis Based on Machine Learning[NCT03949218]3,702 participants (Actual)Observational2018-11-20Completed
Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)[NCT00012558]5,000 participants Interventional1998-09-30Completed
Treatment of Schizophrenia and Related Disorders in Children and Adolescents[NCT00053703]Phase 4116 participants (Actual)Interventional2002-02-28Completed
A Double-Blind, Placebo-Controlled Study of the Effects of Risperdal Consta on Brain Reward Circuitry, Craving and Cocaine Use in Active Cocaine Dependence[NCT00385801]Phase 231 participants (Actual)Interventional2005-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Barnes Akathisia Scale at Week 8

Barnes Akathisia Scale is a clinician rated scale which considers information based on observation of the participant as well as participant report. The scale includes 3 items rated between 0- none to 3 severe and 1 summary item rated between 0 none to 5 severe. All items are summed to obtain the total score. The minimal total score is 0 and the maximal score is 14 with higher scores reflecting more severe akathisia. A score of 4 or more is clinically significant. (NCT00053703)
Timeframe: 8 weeks

Interventionunits on a scale (Mean)
Olanzapine0.19
Risperidone0.41
Molindone1.23

Change From Baseline in Body Mass Index Change, kg/m2, at Week 8

Change from baseline in Body Mass Index Change, kg/m2, at week 8, last observation was carried forward for individuals who withdrew from treatment early. (NCT00053703)
Timeframe: 8 weeks

Interventionkg/m2 (Mean)
Olanzapine1.27
Risperidone2.20
Molindone0.15

Change From Baseline in PANSS Negative Symptom Subscale at Week 8

The PANSS (described above) includes 7 items that reflect negative psychotic symptoms such as amotivation and social withdrawal. As are all items within the PANSS, items are categorically rated by the clinician between 0 - no symptoms to 7 extreme symptoms. The minimal score is 0 reflecting no positive symptoms to 49 reflecting that all items were extreme. Higher scores reflect more severe symptoms. Scores above 18 are usually clinically significant. (NCT00053703)
Timeframe: 8 weeks

Interventionunits on a scale (Mean)
Olanzapine-5.3
Risperidone-5.1
Molindone-5.8

Change From Baseline in PANSS Positive Symptom Subscale Score at 8 Weeks.

The PANSS (described above) includes 7 items that reflect positive psychotic symptoms such as hallucinations and delusions. As are all items within the PANSS, items are categorically rated by the clinician between 0 - no symptoms to 7 extreme symptoms. The minimal score is 0 reflecting no positive symptoms to 49 reflecting that all items were extreme. Higher scores reflect more severe symptoms. Scores above 18 are usually clinically significant. (NCT00053703)
Timeframe: 8 weeks

Interventionunits on a scale (Mean)
Olanzapine-8.9
Risperidone-8.4
Molindone-8.8

Change From Baseline in Positive and Negative Syndrome Scale (PANSS) Total Score at 8 Weeks

Assessed with the Positive and Negative Syndrome Scale in which a clinician rates various psychotic symptoms on the basis of observation of the participant, interview with the participant, and review of all other available information including informant reports. The scale consists of 30 items which are rated categorically between 1 - no symptoms to 7 - extreme symptoms. The minimal score is 0 and the maximal score is 210, with higher scores reflecting more symptoms. Typically scores > that 60 are considered clinically significant. (NCT00053703)
Timeframe: 8 weeks

Interventionunits on a scale (Mean)
Olanzapine-26.6
Risperidone-23.7
Molindone-27.0

Change From Baseline in Weight at Week 8

change in weight from baseline to week 8 in kg (NCT00053703)
Timeframe: 8 weeks

InterventionKg (Mean)
Olanzapine6.12
Risperidone3.64
Molindone0.34

Cocaine Craving

The University of Minnesota Cocaine Craving Scale was performed to assess cocaine craving. The scale contains 1 continuous scale for intensity and 2 categorical scales for frequency and duration of craving episodes. The continuous scale for craving intensity ranges from 0 (no craving at all in the past week) to 10 (a great deal of craving in the past week) (NCT00385801)
Timeframe: 12 weeks

Interventionunits on a scale (Mean)
PlaceboNA
RisperidoneNA

Cocaine Use by Quantitative Urine Samples

After randomization, participants provided urine samples every week for the first 3 weeks and then every 2 weeks for 8 weeks, up to 7 samples per participant. The average visits with cocaine negative urine samples per participant are reported below (NCT00385801)
Timeframe: 12 weeks

Interventionvisit with negative UBE (Mean)
Placebo1.81
Risperidone Consta0.87

Reviews

13 reviews available for risperidone and Depression, Involutional

ArticleYear
Efficacy and safety/tolerability of antipsychotics in the treatment of adult patients with major depressive disorder: a systematic review and meta-analysis.
    Psychological medicine, 2023, Volume: 53, Issue:9

    Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzothiaze

2023
Systematic review and meta-analysis of augmentation and combination treatments for early-stage treatment-resistant depression.
    Journal of psychopharmacology (Oxford, England), 2023, Volume: 37, Issue:3

    Topics: Adult; Aripiprazole; Depression; Depressive Disorder, Major; Humans; Ketamine; Risperidone

2023
Efficacy and acceptability of second-generation antipsychotics with antidepressants in unipolar depression augmentation: a systematic review and network meta-analysis.
    Psychological medicine, 2022, Volume: 52, Issue:12

    Topics: Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Depressive Disorder, Major; Humans; Netwo

2022
Atypical antipsychotics for disruptive behaviour disorders in children and youths.
    The Cochrane database of systematic reviews, 2017, 08-09, Volume: 8

    Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety Disorders; Attention Deficit and Disruptive Be

2017
Meta-analysis on the efficacy and tolerability of the augmentation of antidepressants with atypical antipsychotics in patients with major depressive disorder.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2014, Volume: 47, Issue:7

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines;

2014
Second-generation antipsychotics in major depressive disorder: update and clinical perspective.
    Current opinion in psychiatry, 2011, Volume: 24, Issue:1

    Topics: Adult; Amisulpride; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Depr

2011
Second-generation antipsychotics for major depressive disorder and dysthymia.
    The Cochrane database of systematic reviews, 2010, Dec-08, Issue:12

    Topics: Amisulpride; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Depressive

2010
Use of risperidone as augmentation treatment for major depressive disorder.
    The Annals of pharmacotherapy, 2011, Volume: 45, Issue:1

    Topics: Antipsychotic Agents; Depressive Disorder, Major; Dopamine Antagonists; Drug Therapy, Combination; H

2011
Atypical antipsychotics for disruptive behaviour disorders in children and youths.
    The Cochrane database of systematic reviews, 2012, Sep-12, Issue:9

    Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety Disorders; Attention Deficit and Disruptive Be

2012
Possible induction of mania or hypomania by atypical antipsychotics: an updated review of reported cases.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:11

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depressive Disorde

2004
Creating more effective antidepressants: clues from the clinic.
    Drug discovery today, 2006, Volume: 11, Issue:13-14

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Dep

2006
Augmentation of antidepressants with atypical antipsychotics: a review of the current literature.
    Journal of psychiatric practice, 2008, Volume: 14, Issue:1

    Topics: Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Clozapine; Depressive Disorder, Major;

2008
Use of atypical antipsychotics in mood disorders.
    Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:7

    Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Clozapine; Depres

2001

Trials

14 trials available for risperidone and Depression, Involutional

ArticleYear
Difference in remission in a Chinese population with anxious versus nonanxious treatment-resistant depression: a report of OPERATION study.
    Journal of affective disorders, 2013, Sep-25, Volume: 150, Issue:3

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Anxiety Disorders; Buspirone; China; Comorbidity; Cy

2013
Impact of self-reported juvenile abuse on treatment outcome in patients with major depressive disorder.
    Journal of affective disorders, 2013, Volume: 151, Issue:1

    Topics: Adolescent; Adult; Adult Survivors of Child Abuse; Aged; Antidepressive Agents; Depressive Disorder,

2013
Management of depressive symptoms in schizophrenia.
    Clinical schizophrenia & related psychoses, 2015, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzocyclohe

2015
Management of depressive symptoms in schizophrenia.
    Clinical schizophrenia & related psychoses, 2015, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzocyclohe

2015
Management of depressive symptoms in schizophrenia.
    Clinical schizophrenia & related psychoses, 2015, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzocyclohe

2015
Management of depressive symptoms in schizophrenia.
    Clinical schizophrenia & related psychoses, 2015, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzocyclohe

2015
Comparative efficacy between clozapine and other atypical antipsychotics on depressive symptoms in patients with schizophrenia: analysis of the CATIE phase 2E data.
    Schizophrenia research, 2015, Volume: 161, Issue:2-3

    Topics: Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clozapine; Depressive

2015
A randomized, placebo-controlled trial of risperidone augmentation for patients with difficult-to-treat unipolar, non-psychotic major depression.
    Journal of psychiatric research, 2009, Volume: 43, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-B

2009
Efficacy of risperidone augmentation to antidepressants in the management of suicidality in major depressive disorder: a randomized, double-blind, placebo-controlled pilot study.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:8

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Diagnostic and Stati

2008
Progressive gray matter reduction of the superior temporal gyrus during transition to psychosis.
    Archives of general psychiatry, 2009, Volume: 66, Issue:4

    Topics: Adolescent; Adult; Antipsychotic Agents; Atrophy; Bipolar Disorder; Cognitive Behavioral Therapy; Co

2009
A pilot study of the efficacy and safety of paroxetine augmented with risperidone, valproate, buspirone, trazodone, or thyroid hormone in adult Chinese patients with treatment-resistant major depression.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:5

    Topics: Buspirone; China; Depressive Disorder, Major; Double-Blind Method; Drug Resistance; Drug Therapy, Co

2011
Comparison of olanzapine and risperidone in the treatment of psychosis and associated behavioral disturbances in patients with dementia.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005, Volume: 13, Issue:8

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiaze

2005
Treatment-resistant bipolar depression: a STEP-BD equipoise randomized effectiveness trial of antidepressant augmentation with lamotrigine, inositol, or risperidone.
    The American journal of psychiatry, 2006, Volume: 163, Issue:2

    Topics: Adult; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Depressive Di

2006
Serum monitoring of antipsychotic drug levels during concomitant administration of sertraline and antipsychotic medication.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2006, Volume: 51, Issue:11

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Comorbidity; Depressive Disorder, Ma

2006
Treatment of early-onset schizophrenia spectrum disorders (TEOSS): rationale, design, and methods.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2007, Volume: 46, Issue:8

    Topics: Adolescent; Adult; Age of Onset; Antipsychotic Agents; Benzodiazepines; Child; Comorbidity; Depressi

2007
Risperidone for treatment-refractory major depressive disorder: a randomized trial.
    Annals of internal medicine, 2007, Nov-06, Volume: 147, Issue:9

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Do

2007
A randomized, double-blind, placebo-controlled trial of long-acting risperidone in cocaine-dependent men.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:3

    Topics: Adult; Antipsychotic Agents; Cocaine-Related Disorders; Delayed-Action Preparations; Depressive Diso

2008

Other Studies

49 other studies available for risperidone and Depression, Involutional

ArticleYear
Discovery of Novel and Potent
    Journal of medicinal chemistry, 2021, 05-13, Volume: 64, Issue:9

    Topics: Action Potentials; Allosteric Regulation; Animals; Antidepressive Agents; Binding Sites; Cell Surviv

2021
Duration of Untreated Psychosis Correlates With Brain Connectivity and Morphology in Medication-Naïve Patients With First-Episode Psychosis.
    Biological psychiatry. Cognitive neuroscience and neuroimaging, 2020, Volume: 5, Issue:2

    Topics: Adult; Antipsychotic Agents; Brain; Depressive Disorder, Major; Female; Humans; Magnetic Resonance I

2020
Duration of Untreated Psychosis Correlates With Brain Connectivity and Morphology in Medication-Naïve Patients With First-Episode Psychosis.
    Biological psychiatry. Cognitive neuroscience and neuroimaging, 2020, Volume: 5, Issue:2

    Topics: Adult; Antipsychotic Agents; Brain; Depressive Disorder, Major; Female; Humans; Magnetic Resonance I

2020
Duration of Untreated Psychosis Correlates With Brain Connectivity and Morphology in Medication-Naïve Patients With First-Episode Psychosis.
    Biological psychiatry. Cognitive neuroscience and neuroimaging, 2020, Volume: 5, Issue:2

    Topics: Adult; Antipsychotic Agents; Brain; Depressive Disorder, Major; Female; Humans; Magnetic Resonance I

2020
Duration of Untreated Psychosis Correlates With Brain Connectivity and Morphology in Medication-Naïve Patients With First-Episode Psychosis.
    Biological psychiatry. Cognitive neuroscience and neuroimaging, 2020, Volume: 5, Issue:2

    Topics: Adult; Antipsychotic Agents; Brain; Depressive Disorder, Major; Female; Humans; Magnetic Resonance I

2020
Risperidone-Induced Acute Urinary Retention in a Patient With Major Depressive Disorder With Psychotic Features: a Case Report.
    American journal of therapeutics, 2021, Jun-21, Volume: 28, Issue:5

    Topics: Antipsychotic Agents; Depressive Disorder, Major; Humans; Psychotic Disorders; Risperidone; Urinary

2021
The incidence, psychiatric co-morbidity and pharmacological treatment of severe mental disorders in children and adolescents.
    European psychiatry : the journal of the Association of European Psychiatrists, 2018, Volume: 49

    Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Child; Child, Preschool; Comorbidity; Depressive Dis

2018
Selective Serotonin Reuptake Inhibitors Reduce Longitudinal Growth in Risperidone-Treated Boys.
    The Journal of pediatrics, 2018, Volume: 201

    Topics: Adolescent; Antipsychotic Agents; Body Mass Index; Child; Child, Preschool; Depressive Disorder, Maj

2018
Studies on Prostaglandin-Endoperoxide Synthase 1: Lower Levels in Schizophrenia and After Treatment with Antipsychotic Drugs in Conjunction with Aspirin.
    The international journal of neuropsychopharmacology, 2018, 03-01, Volume: 21, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Aspirin; Bipolar Disorder; B

2018
Electroencephalogram Modifications Associated With Atypical Strict Antipsychotic Monotherapies.
    Journal of clinical psychopharmacology, 2018, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Cerebral Cortex; Cloz

2018
[Antipsychotics -- do they exist?].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2014, Volume: 16, Issue:2

    Topics: Adaptation, Psychological; Affect; Antipsychotic Agents; Aripiprazole; Clinical Trials as Topic; Cor

2014
Effectiveness of aripiprazole, olanzapine, quetiapine, and risperidone augmentation treatment for major depressive disorder: a nationwide population-based study.
    The Journal of clinical psychiatry, 2014, Volume: 75, Issue:9

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Depressive Disorder, Major; Dibenz

2014
Elucidating the transdiagnostic dimensional structure of trauma-related psychopathology: Findings from VA cooperative study 504 - risperidone treatment for military service related chronic post traumatic stress disorder.
    Journal of affective disorders, 2015, Feb-01, Volume: 172

    Topics: Adult; Aged; Antipsychotic Agents; Arousal; Comorbidity; Depressive Disorder, Major; Factor Analysis

2015
A novel clinical observation in neuroleptic malignant-like syndrome: first demonstration of early progression of hydrocephalus.
    Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:2

    Topics: Aged; Antipsychotic Agents; Depressive Disorder, Major; Disease Progression; Fatal Outcome; Female;

2015
Staying Up at Night: Overlapping Bipolar and Obsessive-Compulsive Disorder Symptoms in an Adolescent with Autism Spectrum Disorder.
    Journal of child and adolescent psychopharmacology, 2016, Volume: 26, Issue:1

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Autism Spectrum Disorder

2016
Antipsychotic pharmacogenomics in first episode psychosis: a role for glutamate genes.
    Translational psychiatry, 2016, Feb-23, Volume: 6

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder, Major; Female; Genome-Wide Assoc

2016
Comparative effectiveness of long-acting injectable risperidone vs. long-acting injectable first-generation antipsychotics in bipolar disorder.
    Journal of affective disorders, 2016, Volume: 197

    Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Comparative Effectiveness Research; Delay

2016
Atypical Antipsychotics and the Risks of Acute Kidney Injury and Related Outcomes Among Older Adults: A Replication Analysis and an Evaluation of Adapted Confounding Control Strategies.
    Drugs & aging, 2017, Volume: 34, Issue:3

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Bipolar Disorde

2017
Electroconvulsive therapy in a patient with concomitant depression and charcot-marie-tooth disease.
    The American journal of psychiatry, 2008, Volume: 165, Issue:6

    Topics: Aged; Charcot-Marie-Tooth Disease; Combined Modality Therapy; Comorbidity; Contraindications; Depres

2008
Addition of risperidone to sertraline improves sertraline-resistant refractory depression without influencing plasma concentrations of sertraline and desmethylsertraline.
    Human psychopharmacology, 2008, Volume: 23, Issue:8

    Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Depress

2008
Patient-rated troubling symptoms of depression instrument results correlate with traditional clinician- and patient-rated measures: a secondary analysis of a randomized, double-blind, placebo-controlled trial.
    Journal of affective disorders, 2009, Volume: 118, Issue:1-3

    Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Double-Blind M

2009
Olanzapine/fluoxetine combination for the treatment of mixed depression in bipolar I disorder: a post hoc analysis.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:10

    Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Bipolar Diso

2009
Side-effects of generic.
    Psychiatria Danubina, 2010, Volume: 22, Issue:1

    Topics: Affective Disorders, Psychotic; Aged; Antipsychotic Agents; Cost Savings; Croatia; Depressive Disord

2010
Hyperprolactinaemia - a risperidone side-effect.
    Psychiatria Danubina, 2010, Volume: 22, Issue:1

    Topics: Affective Disorders, Psychotic; Antipsychotic Agents; Depressive Disorder, Major; Dose-Response Rela

2010
Improvement in drug-induced parkinsonism with electroconvulsive therapy.
    The American journal of geriatric pharmacotherapy, 2011, Volume: 9, Issue:3

    Topics: Aged; Antiparkinson Agents; Antipsychotic Agents; Depressive Disorder, Major; Electroconvulsive Ther

2011
Adjunctive antipsychotics for major depression.
    The Medical letter on drugs and therapeutics, 2011, Sep-19, Volume: 53, Issue:1373

    Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Depressive Disorder, Major; Dibenzothiazepines;

2011
Factors associated with the prescribing of olanzapine, quetiapine, and risperidone in patients with bipolar and related affective disorders.
    Pharmacotherapy, 2011, Volume: 31, Issue:8

    Topics: Academic Medical Centers; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depressive

2011
Electroconvulsive therapy in a physically restrained man with comorbid major depression, severe agoraphobia with panic disorder, and histrionic personality disorder.
    The journal of ECT, 2012, Volume: 28, Issue:1

    Topics: Adult; Agoraphobia; Antimanic Agents; Antipsychotic Agents; Depressive Disorder, Major; Electroconvu

2012
Sex differences in human lymphoblastoid cells sensitivities to antipsychotic drugs.
    Journal of molecular neuroscience : MN, 2013, Volume: 49, Issue:3

    Topics: Anti-Inflammatory Agents; Antidepressive Agents; Antineoplastic Agents; Antipsychotic Agents; Cell D

2013
Depression and dysphoria in adult and adolescent patients with Tourette's disorder treated with risperidone.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:11

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Depression; Depressive Disorder, Major; Dose-Response

2002
Risperidone-induced galactorrhoea: a case series.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2003, Volume: 48, Issue:2

    Topics: Adult; Depressive Disorder, Major; Female; Galactorrhea; Humans; Risperidone; Selective Serotonin Re

2003
[Plasma prolactin level and incidence of adverse endocrinologic effects during therapy with atypical neuroleptics].
    Psychiatrische Praxis, 2003, Volume: 30 Suppl 2

    Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzothiaze

2003
Augmentation of milnacipran by risperidone in treatment for major depression.
    The international journal of neuropsychopharmacology, 2004, Volume: 7, Issue:1

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Cyclopropanes; Depressi

2004
Risperidone-induced rabbit syndrome in mood disorder.
    European psychiatry : the journal of the Association of European Psychiatrists, 2004, Volume: 19, Issue:7

    Topics: Antipsychotic Agents; Depressive Disorder, Major; Diagnosis, Differential; Hallucinations; Humans; M

2004
Child and adolescent electroconvulsive therapy: a case report.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2004, Volume: 5, Issue:4

    Topics: Adolescent; Antipsychotic Agents; Child; Cognition Disorders; Combined Modality Therapy; Depressive

2004
Low-dose risperidone and quetiapine as monotherapy for comorbid anxiety and depression.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:4

    Topics: Adult; Aged; Antipsychotic Agents; Anxiety Disorders; Comorbidity; Depressive Disorder, Major; Diben

2005
Effectiveness of risperidone in psychogenic stiff neck.
    CNS spectrums, 2005, Volume: 10, Issue:6

    Topics: Antipsychotic Agents; Depressive Disorder, Major; Female; Humans; Middle Aged; Risperidone; Torticol

2005
Genotype A1/A2 associated with neuroleptic malignant syndrome.
    Bipolar disorders, 2005, Volume: 7, Issue:4

    Topics: Adult; Alleles; Antipsychotic Agents; Citalopram; Depressive Disorder, Major; DNA Primers; Humans; M

2005
Postpartum depression without delivering a child?
    Acta psychiatrica Scandinavica, 2005, Volume: 112, Issue:3

    Topics: Alprazolam; Anti-Anxiety Agents; Depression, Postpartum; Depressive Disorder, Major; Diagnostic and

2005
[Brief case report. Duloxetine in Cotard syndrome].
    Psychiatrische Praxis, 2005, Volume: 32, Issue:8

    Topics: Affective Disorders, Psychotic; Aged; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines;

2005
Possible antipsychotic effect of fluvoxamine.
    CNS spectrums, 2005, Volume: 10, Issue:10

    Topics: Antipsychotic Agents; Citalopram; Delayed-Action Preparations; Depressive Disorder, Major; Drug Admi

2005
A case of pulmonary thromboembolism and rhabdomyolysis during therapy with mirtazapine and risperidone.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:5

    Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Comorbidity; Depressive Disorder, Maj

2006
Risperidone-induced hyperprolactinemia in adolescents: A case series.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:7

    Topics: Adolescent; Age Factors; Antipsychotic Agents; Depressive Disorder, Major; Diagnostic and Statistica

2006
Changes in plasma cholesterol in mood disorder patients: does treatment make a difference?
    Journal of affective disorders, 2007, Volume: 99, Issue:1-3

    Topics: Acute Disease; Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Antimanic Agents; A

2007
Obsessive-compulsive disorder followed by psychotic episode in long-term ecstasy misuse.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 2

    Topics: Adolescent; Amphetamine-Related Disorders; Antidepressive Agents, Tricyclic; Antipsychotic Agents; B

2009
Summaries for patients. Can adding risperidone to antidepressant therapy relieve persistent symptoms of depression?
    Annals of internal medicine, 2007, Nov-06, Volume: 147, Issue:9

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Do

2007
Risperidone-associated galactorrhea in a male teenager.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2001, Volume: 40, Issue:5

    Topics: Adolescent; Antipsychotic Agents; Depressive Disorder, Major; Galactorrhea; Humans; Male; Risperidon

2001
[Paroxetine augmentation with risperidone in therapy-resistant depression].
    Psychiatrische Praxis, 2001, Volume: 28, Issue:8

    Topics: Aged; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Therapy, Combination; Femal

2001
Intractable depression or psychosis.
    Acta psychiatrica Scandinavica, 2001, Volume: 104, Issue:5

    Topics: Aged; Depressive Disorder, Major; Diagnosis, Differential; Dose-Response Relationship, Drug; Female;

2001
Short report: comparison of patient satisfaction and burden of adverse effects with novel and conventional neuroleptics: a naturalistic study.
    Schizophrenia bulletin, 2001, Volume: 27, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Depressive Disorder, Majo

2001
Exacerbation of idiopathic priapism with risperidone-citalopram combination.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:3

    Topics: Adrenergic Antagonists; Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Cital

2002
Rabbit syndrome secondary to risperidone.
    Pharmacotherapy, 2002, Volume: 22, Issue:4

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Cholinergic Antagonists; Depressive Disorder, M

2002