Page last updated: 2024-11-03

risperidone and Depression, Endogenous

risperidone has been researched along with Depression, Endogenous in 68 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Research Excerpts

ExcerptRelevanceReference
"2 years) inpatients with depressive and anxiety disorders who were treated with risperidone (median doses per day 1."9.12Low-dose risperidone augmentation of antidepressants or anxiolytics is associated with hyperprolactinemia. ( Bares, M; Horacek, J; Kopecek, M; Mohr, P, 2006)
"To determine the effectiveness of amisulpride on depression in patients with schizophrenia, in comparison to risperidone."9.12Amisulpride versus risperidone in the treatment of depression in patients with schizophrenia: a randomized, open-label, controlled trial. ( Hwang, MY; Kim, JM; Kim, SW; Lee, JH; Lee, SH; Shin, IS; Yang, SJ; Yoon, BH; Yoon, JS, 2007)
"Seventeen (85%) of 20 patients (13 bipolar, 4 major depressive disorder) showed complete or partial improvement after treatment with risperidone doses ranging from 1 to 6 mg/day (mean = 3."9.08Risperidone in the treatment of affective illness and obsessive-compulsive disorder. ( Jacobsen, FM, 1995)
"This retrospective chart review was conducted to determine the effectiveness of olanzapine, risperidone, quetiapine, and ziprasidone when given in a fee-for-service setting as anti-depressant augmentation agents to patients with treatment-resistant, nonpsychotic major depressive disorder (DSM-IV)."7.72The effectiveness of olanzapine, risperidone, quetiapine, and ziprasidone as augmentation agents in treatment-resistant major depressive disorder. ( Barbee, JG; Conrad, EJ; Jamhour, NJ, 2004)
"In studies of patients with schizophrenia, the atypical antipsychotic risperidone has been shown to be comparable in efficacy to haloperidol and, at dosages of 4 to 8 mg/day, to have a lower rate of extrapyramidal side effects."7.69Clinical predictors of acute risperidone response in schizophrenia, schizoaffective disorder, and psychotic mood disorders. ( Balistreri, TM; DePriest, M; Holtman, HM; Keck, PE; Kizer, DL; McElroy, SL; Strakowski, SM; Wilson, DR, 1995)
"Risperidone-treated subjects with a greater degree of acute mood change were both 3."6.69The course of depressive symptoms in predicting relapse in schizophrenia: a double-blind, randomized comparison of olanzapine and risperidone. ( Andersen, SW; Tollefson, GD; Tran, PV, 1999)
"We conducted a post hoc analysis of an international, multicenter, double-blind, 28-week study of 339 patients who met DSM-IV criteria for schizophrenia, schizophreniform, or schizoaffective disorder and were randomized to treatment with either olanzapine or risperidone."6.19Should we consider mood disturbance in schizophrenia as an important determinant of quality of life? ( Andersen, SW; Tollefson, GD, 1999)
"2 years) inpatients with depressive and anxiety disorders who were treated with risperidone (median doses per day 1."5.12Low-dose risperidone augmentation of antidepressants or anxiolytics is associated with hyperprolactinemia. ( Bares, M; Horacek, J; Kopecek, M; Mohr, P, 2006)
"To determine the effectiveness of amisulpride on depression in patients with schizophrenia, in comparison to risperidone."5.12Amisulpride versus risperidone in the treatment of depression in patients with schizophrenia: a randomized, open-label, controlled trial. ( Hwang, MY; Kim, JM; Kim, SW; Lee, JH; Lee, SH; Shin, IS; Yang, SJ; Yoon, BH; Yoon, JS, 2007)
"Thirty-six subjects who fulfilled DSM-IV diagnostic criteria for major depressive disorder were given fluvoxamin, 50 or 75 mg/day, with risperidone, 0."5.10An open pilot study combining risperidone and a selective serotonin reuptake inhibitor as initial antidepressant therapy. ( Ashby, CR; Hirose, S, 2002)
"In 8 patients with major depressive disorder without psychotic features (DSM-IV) who had not responded to an SSRI, risperidone was added to the ongoing SSRI treatment."5.09Risperidone augmentation of selective serotonin reuptake inhibitors in major depression. ( Nelson, JC; Ostroff, RB, 1999)
"Seventeen (85%) of 20 patients (13 bipolar, 4 major depressive disorder) showed complete or partial improvement after treatment with risperidone doses ranging from 1 to 6 mg/day (mean = 3."5.08Risperidone in the treatment of affective illness and obsessive-compulsive disorder. ( Jacobsen, FM, 1995)
"Cariprazine was approved for treating schizophrenia and bipolar disorder, and currently is being evaluated for treating depression in clinical trials in the United States."4.98Use of cariprazine in psychiatric disorders: A systematic review. ( Chhatlani, A; Farheen, SA; Setty, MJ; Tampi, RR, 2018)
"Treatment of acute mania with second-generation antipsychotics has been claimed to involve a lower risk of switch to depression than haloperidol."4.89Lower rate of depressive switch following antimanic treatment with second-generation antipsychotics versus haloperidol. ( Capapey, J; Colom, F; Goikolea, JM; Grande, I; Sanchez-Moreno, J; Torres, I; Undurraga, J; Valentí, M; Vieta, E, 2013)
" The receptor profile for risperidone, an atypical antipsychotic with demonstrated efficacy in schizophrenia, is consistent with possible antidepressant activity."4.81Risperidone: review of its therapeutic utility in depression. ( Myers, JE; Thase, ME, 2001)
"This retrospective chart review was conducted to determine the effectiveness of olanzapine, risperidone, quetiapine, and ziprasidone when given in a fee-for-service setting as anti-depressant augmentation agents to patients with treatment-resistant, nonpsychotic major depressive disorder (DSM-IV)."3.72The effectiveness of olanzapine, risperidone, quetiapine, and ziprasidone as augmentation agents in treatment-resistant major depressive disorder. ( Barbee, JG; Conrad, EJ; Jamhour, NJ, 2004)
"In studies of patients with schizophrenia, the atypical antipsychotic risperidone has been shown to be comparable in efficacy to haloperidol and, at dosages of 4 to 8 mg/day, to have a lower rate of extrapyramidal side effects."3.69Clinical predictors of acute risperidone response in schizophrenia, schizoaffective disorder, and psychotic mood disorders. ( Balistreri, TM; DePriest, M; Holtman, HM; Keck, PE; Kizer, DL; McElroy, SL; Strakowski, SM; Wilson, DR, 1995)
" A total of 123 patients (62 RIS; 61 HAL/AMI) were included; the mean daily dosage at endpoint was 6."2.69Risperidone versus haloperidol and amitriptyline in the treatment of patients with a combined psychotic and depressive syndrome. ( Benkert, O; Hillert, A; Müller, MJ; Müller-Siecheneder, F; Szegedi, A; Wetzel, H, 1998)
"Risperidone-treated subjects with a greater degree of acute mood change were both 3."2.69The course of depressive symptoms in predicting relapse in schizophrenia: a double-blind, randomized comparison of olanzapine and risperidone. ( Andersen, SW; Tollefson, GD; Tran, PV, 1999)
" Adding risperidone to mirtazapine probably does not necessitate a change of the dosage of either drug, but more extensive investigations are needed."2.69Lack of drug interactions between mirtazapine and risperidone in psychiatric patients: a pilot study. ( Doorschot, CH; Loonen, AJ; Oostelbos, MC; Sitsen, JM, 1999)
"Risperidone has been shown to be a safe and effective atypical antipsychotic agent."2.44Novel uses for risperidone: focus on depressive, anxiety and behavioral disorders. ( Bradbury, C; da Silva, TL; McKay, M; Ravindran, AV, 2007)
"Schizophrenia is also associated with aggression directed at self and others."2.41The efficacy of atypical antipsychotics in the treatment of depressive symptoms, hostility, and suicidality in patients with schizophrenia. ( Keck, PE; McElroy, SL; Strakowski, SM, 2000)
"Olanzapine is a novel antipsychotic agent displaying a unique and pleotrophic pharmacology, which distinguishes it from other existing treatments."2.40Review of recent clinical studies with olanzapine. ( Kuntz, AJ; Tollefson, GD, 1999)
"The effects of neuroleptics on bipolar depression need further study."2.39Antipsychotics in bipolar disorder. ( Gelenberg, AJ; Hopkins, HS, 1996)
" A cumulative dose-response relationship was observed (test for trend, p < 0."1.62Atypical Antipsychotics Augmentation in Patients with Depressive Disorder and Risk of Subsequent Dementia: A Nationwide Population-Based Cohort Study. ( Ha, TH; Kim, DK; Kim, H; Kim, J; Kim, K; Lee, EM; Lee, H; Lewis, M; Myung, W; Won, HH, 2021)
"Morgellons disease is a condition, which is widely discussed on the internet and patients often self-diagnose."1.48Morgellons disease: experiences of an integrated multidisciplinary dermatology team to achieve positive outcomes. ( Bewley, A; Mohandas, P; Taylor, R, 2018)
"This report shows symptomatic recurrences persisting more than 8 months."1.33Hallucinogen persisting perception disorder after psilocybin consumption: a case study. ( Abadie, P; Dollfus, S; Espiard, ML; Halbecq, I; Lecardeur, L, 2005)

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's30 (44.12)18.2507
2000's30 (44.12)29.6817
2010's7 (10.29)24.3611
2020's1 (1.47)2.80

Authors

AuthorsStudies
Kim, J1
Ha, TH1
Kim, K1
Lee, EM1
Kim, H1
Kim, DK1
Won, HH1
Lewis, M1
Lee, H1
Myung, W1
Mohandas, P1
Bewley, A1
Taylor, R1
Chhatlani, A1
Farheen, SA1
Setty, MJ1
Tampi, RR1
Connolly, JG1
Toomey, TJ1
Schneeweiss, MC1
Taoka, H1
Hamamura, T1
Endo, S1
Miyata, S1
Toma, K1
Ishihara, T1
Kuroda, S1
Pandina, GJ1
Garibaldi, GM1
Revicki, DA1
Kleinman, L1
Turkoz, I2
Kujawa, MJ1
Mahmoud, RA1
Manousaridis, K1
Gupta, R1
Goikolea, JM1
Colom, F1
Torres, I1
Capapey, J1
Valentí, M1
Undurraga, J1
Grande, I1
Sanchez-Moreno, J1
Vieta, E1
Singh, V1
Bowden, CL1
Mintz, J1
Hirose, S1
Ashby, CR1
Myers, JE1
Thase, ME1
Viner, MW1
Chen, Y1
Bakshi, I1
Kamper, P1
Sharpley, AL1
Bhagwagar, Z1
Hafizi, S1
Whale, WR1
Gijsman, HJ1
Cowen, PJ1
Hori, K1
Oda, T1
Tominaga, I1
Inada, T1
Theodoulou, G1
Milner, G1
Jumaian, A1
Hoeh, N1
Gyulai, L1
Weintraub, D1
Streim, J1
Barbee, JG1
Conrad, EJ1
Jamhour, NJ1
Englert, I1
Espiard, ML1
Lecardeur, L1
Abadie, P1
Halbecq, I1
Dollfus, S1
Ahn, MS1
Sims, KB1
Frazier, JA1
Bloch, MH1
Landeros-Weisenberger, A1
Kelmendi, B1
Coric, V1
Bracken, MB1
Leckman, JF1
Cawrse, N1
Wilson, S1
Williams, M1
Burge, T1
Kopecek, M1
Bares, M1
Horacek, J1
Mohr, P1
Ruhrmann, S1
Kissling, W1
Lesch, OM1
Schmauss, M1
Seemann, U1
Philipp, M1
Ravindran, AV1
Bradbury, C1
McKay, M1
da Silva, TL1
Kim, SW1
Shin, IS1
Kim, JM1
Lee, SH1
Lee, JH1
Yoon, BH1
Yang, SJ1
Hwang, MY1
Yoon, JS1
Alexopoulos, GS1
Canuso, CM1
Gharabawi, GM1
Bossie, CA1
Greenspan, A1
Reynolds, C1
Carroll, BJ1
Dwight, MM1
Keck, PE4
Stanton, SP1
Strakowski, SM4
McElroy, SL3
Sussman, N1
Jones, BD1
Purdon, SE1
Labelle, A1
Finlayson, R1
Giakas, WJ1
Jacobsen, FM1
Wilson, DR1
Kizer, DL1
Balistreri, TM1
Holtman, HM1
DePriest, M1
Koek, RJ1
Kessler, CC1
Benazzi, F1
Gelenberg, AJ1
Hopkins, HS1
Negrón, AE1
Leiderman, EA1
Parkadavil, M1
Cienfuegos, A1
Javitt, DC1
Farah, A1
Beale, MD1
Kellner, CH1
Feeney, DJ1
Klykylo, W1
Welner, M1
Koponen, HJ1
Konrad, C1
Schormair, C1
Eikelmann, B1
Telger, K1
Bernhard, R1
O'Connor, M1
Silver, H1
Saran, BM1
Müller-Siecheneder, F1
Müller, MJ1
Hillert, A2
Szegedi, A1
Wetzel, H2
Benkert, O2
Lane, HY2
Chang, WH2
Tollefson, GD3
Andersen, SW2
Kuntz, AJ1
Ostroff, RB1
Nelson, JC1
Chiu, WC1
Tran, PV1
Loonen, AJ1
Doorschot, CH1
Oostelbos, MC1
Sitsen, JM1
Iakovlev, VA1
Kaplan, M1
Blass, DM1
Pearson, VE1
Stoll, AL1
Haura, G1
Hansen, L1
Wilkinson, DG1
Leslie, DL1
Rosenheck, R1
Janicak, PG1
Davis, JM1
Kasckow, JW1
Tugrul, K1
Dowd, SM1
Strong, J1
Sharma, RP1
Normann, C1
Lieb, K1
Walden, J1
Parker, G1
Malhi, G1
Weimer, E1
Braus, DF1
Cavus, I1
Thome, J1
Maier, W1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Quetiapine Augmentation Versus Clomipramine Augmentation of Selective Serotonin Reuptake Inhibitors for Obsessive-compulsive Disorder Patients That do Not Respond to a SSRI Trial: a Randomized Open-trial.[NCT00564564]Phase 421 participants (Actual)Interventional2006-01-31Completed
Ketamine Treatment for Pediatric-Refractory Obsessive-Compulsive Disorder (OCD)[NCT02422290]Phase 1/Phase 25 participants (Actual)Interventional2015-03-31Completed
An Open-Label Trial of Epidiolex in the Treatment of Obsessive Compulsive Disorder and Related Disorders: Proof of Concept Study[NCT04978428]Phase 215 participants (Anticipated)Interventional2022-04-14Recruiting
Open Label Study for the Use of Transcranial Ultrasound Treatment of Obsessive-Compulsive Disorder[NCT04775875]30 participants (Anticipated)Interventional2020-12-01Enrolling by invitation
Effectiveness of Paliperidone ER(Invega®) on Depressive Symptoms of Schizophrenia Patients: A 8-week Open-label Prospective, Non-comparative Study[NCT01399450]Phase 411 participants (Actual)Interventional2011-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS)

The CY-BOCS is a semi-structured measure of OCD severity with excellent inter-rater reliability, internal consistency, and test-retest reliability. It is validated in those starting at age 7 and used in studies up to age 20. The CYBOCS differs from the adult YBOCS only in its use of simpler language. The CY-BOCS consists of 10 items which are summed up to derive the total CY-BOCS score. The total score ranges from 0-40 with higher scores indicating greater severity of OCD symptoms. (NCT02422290)
Timeframe: Screening, Baseline, Day 7, Day 17, 3-Month; Baseline and Day 14 pre-specified to be reported

Interventionscore on a scale (Mean)
CY-BOCS BaselineCY-BOCS Day 14
Ketamine Treatment Group29.0026.20

Clinical Global Impressions - Severity Scale (CGI-S)

The CGI-S is a clinician rated 7-point rating scale for the severity of a participant's illness relative to the clinician's experience of working with this particular population. The score ranges from 1-7 with higher scores indicating greater illness severity. (NCT02422290)
Timeframe: Screening, Baseline, Day 7, Day 17, 3-Month; Baseline and Day 14 pre-specified to be reported

Interventionscore on a scale (Mean)
CGI-S BaselineCGI-S Day 14
Ketamine Treatment Group5.805.00

OCD Visual Analogue Scale (OCD-VAS)

"The OCD-VAS is a one-item unipolar scale to assess OCD symptoms over a rapid time frame (No obsessions to Constant obsessions). The scale ranges from 0-10 with higher scores indicating higher presence of obsessions." (NCT02422290)
Timeframe: Screening, Baseline, Day 1-14, 3-Month; Baseline and Day 14 pre-specified to be reported

Interventionscore on a scale (Mean)
OCD-VAS BaselineOCD-VAS Day 14
Ketamine Treatment Group5.005.00

Yale-Brown Obsessive Compulsive Challenge Scale (Y-BOCCS)

"The Y-BOCCS is self-report scale which assesses OCD symptoms on a 5-point likert scale (None to Extreme). It consists of 10 items which are summed up to derive the total Y-BOCCS score. The total score ranges from 0-40 with higher scores indicating higher prevalence of OCD symptoms." (NCT02422290)
Timeframe: Screening, Baseline, Day 1-14, 3-Month; Baseline and Day 14 pre-specified to be reported

Interventionscore on a scale (Mean)
Y-BOCCS BaselineY-BOCCS Day 14
Ketamine Treatment Group18.2516.50

Reviews

14 reviews available for risperidone and Depression, Endogenous

ArticleYear
Use of cariprazine in psychiatric disorders: A systematic review.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2018, Volume: 30, Issue:4

    Topics: Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Depressive Disorder; Humans; Piperazines; Risp

2018
Lower rate of depressive switch following antimanic treatment with second-generation antipsychotics versus haloperidol.
    Journal of affective disorders, 2013, Jan-25, Volume: 144, Issue:3

    Topics: Acute Disease; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disord

2013
Risperidone: review of its therapeutic utility in depression.
    Psychopharmacology bulletin, 2001,Autumn, Volume: 35, Issue:4

    Topics: Animals; Antipsychotic Agents; Depressive Disorder; Humans; Randomized Controlled Trials as Topic; R

2001
Pharmacologic management of psychosis in the elderly: a critical review.
    Journal of geriatric psychiatry and neurology, 2003, Volume: 16, Issue:4

    Topics: Aged; Alzheimer Disease; Benzodiazepines; Bipolar Disorder; Clozapine; Depressive Disorder; Drug Adm

2003
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
Novel uses for risperidone: focus on depressive, anxiety and behavioral disorders.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:11

    Topics: Animals; Anxiety Disorders; Depressive Disorder; Humans; Mental Disorders; Risperidone

2007
The potential benefits of serotonin receptor-specific agents.
    The Journal of clinical psychiatry, 1994, Volume: 55 Suppl

    Topics: Antidepressive Agents; Buspirone; Depressive Disorder; Humans; Isoxazoles; Ondansetron; Piperazines;

1994
Antipsychotics in bipolar disorder.
    The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 9

    Topics: Acute Disease; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; D

1996
Assessing the effects of atypical antipsychotics on negative symptoms. Collaborative Working Group on Clinical Trial Evaluations.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 12

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Delusions; Depressive Disorder; Hallucinati

1998
Atypical antipsychotics for treatment of depression in schizophrenia and affective disorders. Collaborative Working Group on Clinical Trial Evaluations.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 12

    Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Clozapine; Comorb

1998
Should we consider mood disturbance in schizophrenia as an important determinant of quality of life?
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 5

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Comorbidity; D

1999
Review of recent clinical studies with olanzapine.
    The British journal of psychiatry. Supplement, 1999, Issue:37

    Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Depressive Disorder; Drug Resistance; Humans; Olan

1999
The efficacy of atypical antipsychotics in the treatment of depressive symptoms, hostility, and suicidality in patients with schizophrenia.
    The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 3

    Topics: Aggression; Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Clozapine; Depression;

2000
[Augmentation of selective serotonin reuptake inhibitors (SSRI) with atypical antipsychotics in the treatment of depression].
    Fortschritte der Neurologie-Psychiatrie, 2002, Volume: 70, Issue:4

    Topics: Antipsychotic Agents; Benzodiazepines; Depressive Disorder; Drug Therapy, Combination; Humans; Olanz

2002

Trials

14 trials available for risperidone and Depression, Endogenous

ArticleYear
Psychometric evaluation of a Patient-Rated Most Troubling Symptom Scale for Depression: findings from a secondary analysis of a clinical trial.
    International clinical psychopharmacology, 2010, Volume: 25, Issue:2

    Topics: Adult; Aged; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Disability Evalua

2010
Relative effectiveness of adjunctive risperidone on manic and depressive symptoms in mixed mania.
    International clinical psychopharmacology, 2013, Volume: 28, Issue:2

    Topics: Adult; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Depressive Disorder; Diagnostic an

2013
An open pilot study combining risperidone and a selective serotonin reuptake inhibitor as initial antidepressant therapy.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Ambulatory Care; Antipsychotic Agents; Depressive Disorder; Dr

2002
Low-dose risperidone augmentation of antidepressants or anxiolytics is associated with hyperprolactinemia.
    Neuro endocrinology letters, 2006, Volume: 27, Issue:6

    Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Anxiety; Benzodiazepines; D

2006
Efficacy of flupentixol and risperidone in chronic schizophrenia with predominantly negative symptoms.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Jun-30, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Chronic Disease; Data Interpretation, Statistical; De

2007
Amisulpride versus risperidone in the treatment of depression in patients with schizophrenia: a randomized, open-label, controlled trial.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Oct-01, Volume: 31, Issue:7

    Topics: Adolescent; Adult; Amisulpride; Antipsychotic Agents; Depressive Disorder; Electrocardiography; Endp

2007
Placebo-controlled study of relapse prevention with risperidone augmentation in older patients with resistant depression.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2008, Volume: 16, Issue:1

    Topics: Aged; Aged, 80 and over; Citalopram; Depressive Disorder; Double-Blind Method; Drug Therapy, Combina

2008
Risperidone in the treatment of affective illness and obsessive-compulsive disorder.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:9

    Topics: Adult; Ambulatory Care; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Drug Administra

1995
Risperidone versus haloperidol and amitriptyline in the treatment of patients with a combined psychotic and depressive syndrome.
    Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Depr

1998
Should we consider mood disturbance in schizophrenia as an important determinant of quality of life?
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 5

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Comorbidity; D

1999
Risperidone augmentation of selective serotonin reuptake inhibitors in major depression.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:4

    Topics: Adult; Aged; Ambulatory Care; Antipsychotic Agents; Depressive Disorder; Dose-Response Relationship,

1999
The course of depressive symptoms in predicting relapse in schizophrenia: a double-blind, randomized comparison of olanzapine and risperidone.
    Biological psychiatry, 1999, Aug-01, Volume: 46, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Cluster Analysis; Cognition Disorders; Depressive Diso

1999
Lack of drug interactions between mirtazapine and risperidone in psychiatric patients: a pilot study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 10, Issue:1

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Depression; Depressive Disorder

1999
A double-blind, randomized, prospective evaluation of the efficacy and safety of risperidone versus haloperidol in the treatment of schizoaffective disorder.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:4

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Female; Hal

2001

Other Studies

41 other studies available for risperidone and Depression, Endogenous

ArticleYear
Atypical Antipsychotics Augmentation in Patients with Depressive Disorder and Risk of Subsequent Dementia: A Nationwide Population-Based Cohort Study.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 80, Issue:1

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Cohort Studies; Dementia; Depressive Disorder; Female

2021
Morgellons disease: experiences of an integrated multidisciplinary dermatology team to achieve positive outcomes.
    The Journal of dermatological treatment, 2018, Volume: 29, Issue:2

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Antipsychotic

2018
Metabolic monitoring for youths initiating use of second-generation antipsychotics, 2003-2011.
    Psychiatric services (Washington, D.C.), 2015, Volume: 66, Issue:6

    Topics: Adolescent; Affective Disorders, Psychotic; Antipsychotic Agents; Anxiety Disorders; Aripiprazole; B

2015
Antipsychotics possessing antidepressive efficacy increase Golf protein in rat striatum.
    Psychopharmacology, 2008, Volume: 201, Issue:2

    Topics: Amisulpride; Animals; Antipsychotic Agents; Benzodiazepines; Blotting, Western; Clozapine; Corpus St

2008
Risperidone-related bilateral cystoid macular oedema.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2013, Volume: 251, Issue:3

    Topics: Aged; Albuterol; Antipsychotic Agents; Bronchodilator Agents; Depressive Disorder; Female; Fluoresce

2013
Low-dose risperidone augmentation of antidepressants in nonpsychotic depressive disorders with suicidal ideation.
    Journal of clinical psychopharmacology, 2003, Volume: 23, Issue:1

    Topics: Antipsychotic Agents; Depressive Disorder; Dopamine Antagonists; Female; Humans; Middle Aged; Psychi

2003
Risperidone augmentation decreases rapid eye movement sleep and decreases wake in treatment-resistant depressed patients.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:2

    Topics: Administration, Oral; Adult; Antidepressive Agents; Antipsychotic Agents; Cross-Over Studies; Depres

2003
'Awakenings' in demented patients.
    Psychiatry and clinical neurosciences, 2003, Volume: 57, Issue:2

    Topics: Aged; Alzheimer Disease; Antipsychotic Agents; Awareness; Cholinesterase Inhibitors; Delusions; Depr

2003
Neuroleptics and family history of Parkinson diseases: case report.
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 2001, Volume: 7, Issue:3

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Depressive Disorder; Diagnostic Errors; Female;

2001
The effectiveness of olanzapine, risperidone, quetiapine, and ziprasidone as augmentation agents in treatment-resistant major depressive disorder.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:7

    Topics: Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Depressive Disorder; Dibenzothiazepine

2004
[Diphenhydramin-overdose: anticholinergic symptoms, EEG-findings in the course and drug treatment of a gerontopsychiatric patient].
    Psychiatrische Praxis, 2004, Volume: 31 Suppl 1

    Topics: Aged; Brain; Cholinergic Antagonists; Dementia; Depressive Disorder; Diphenhydramine; Drug Therapy,

2004
Hallucinogen persisting perception disorder after psilocybin consumption: a case study.
    European psychiatry : the journal of the Association of European Psychiatrists, 2005, Volume: 20, Issue:5-6

    Topics: Adolescent; Antidepressive Agents; Antipsychotic Agents; Anxiety; Depressive Disorder; Diagnosis, Di

2005
Risperidone-induced psychosis and depression in a child with a mitochondrial disorder.
    Journal of child and adolescent psychopharmacology, 2005, Volume: 15, Issue:3

    Topics: Adolescent; Depressive Disorder; Epilepsy, Tonic-Clonic; Female; Humans; Mitochondrial Diseases; Moo

2005
Neuroleptic malignant syndrome in the burns patient?
    Burns : journal of the International Society for Burn Injuries, 2006, Volume: 32, Issue:5

    Topics: Antipsychotic Agents; Burns; Depressive Disorder; Fatal Outcome; Female; Fever; Humans; Middle Aged;

2006
'Effects of risperidone augmentation in patients with treatment-resistant depression: results of open-label treatment followed by double-blind continuation'.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:10

    Topics: Antipsychotic Agents; Clinical Trials as Topic; Conflict of Interest; Data Interpretation, Statistic

2008
Antidepressant activity and mania associated with risperidone treatment of schizoaffective disorder.
    Lancet (London, England), 1994, Aug-20, Volume: 344, Issue:8921

    Topics: Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Humans; Isoxazoles; Piperidines; Risper

1994
Risperidone treatment for severe negative symptoms.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1994, Volume: 39, Issue:6

    Topics: Adult; Antipsychotic Agents; Clonazepam; Depressive Disorder; Drug Therapy, Combination; Humans; Iso

1994
Risperidone treatment for a Tourette's disorder patient with comorbid obsessive-compulsive disorder.
    The American journal of psychiatry, 1995, Volume: 152, Issue:7

    Topics: Adult; Antipsychotic Agents; Comorbidity; Depressive Disorder; Drug Therapy, Combination; Fluoxetine

1995
Clinical predictors of acute risperidone response in schizophrenia, schizoaffective disorder, and psychotic mood disorders.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:10

    Topics: Adult; Age Factors; Antipsychotic Agents; Bipolar Disorder; Chronic Disease; Depressive Disorder; Dr

1995
Probable induction of mania by risperidone.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:4

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Humans; Male; Risperidone; Serot

1996
Severe depression with risperidone-induced EPS in an elderly schizoaffective patient.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1996, Volume: 41, Issue:3

    Topics: Aged; Antipsychotic Agents; Depressive Disorder; Dose-Response Relationship, Drug; Dyskinesia, Drug-

1996
A naturalistic outcome study of risperidone treatment among hospital patients.
    Psychiatric services (Washington, D.C.), 1996, Volume: 47, Issue:10

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Chronic Disease; Depressive Disorder; Female; Hospita

1996
Risperidone and ECT combination therapy: a case series.
    Convulsive therapy, 1995, Volume: 11, Issue:4

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Combined Modality Therapy; Depressive Disorder; Elect

1995
Risperidone and tardive dyskinesia.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1996, Volume: 35, Issue:11

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Depressive Disorder

1996
Risperidone plus a monoamine oxidase inhibitor for agitated depression crisis.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:6

    Topics: Acute Disease; Adult; Antipsychotic Agents; Depressive Disorder; Humans; Male; Monoamine Oxidase Inh

1996
Risperidone in the treatment of psychosis and concomitant buccolinguomasticatory dyskinesia in the elderly.
    International journal of geriatric psychiatry, 1997, Volume: 12, Issue:3

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Depressive Disorder; Dyskinesia, Drug-Induced; Female

1997
[Risperidone after clozapine in therapy refractory schizoaffective psychosis--a case report].
    Psychiatrische Praxis, 1997, Volume: 24, Issue:2

    Topics: Adult; Amitriptyline; Antipsychotic Agents; Clozapine; Depressive Disorder; Dose-Response Relationsh

1997
Can risperidone be antidepressive and also inhibit aggression?
    The Journal of neuropsychiatry and clinical neurosciences, 1997,Fall, Volume: 9, Issue:4

    Topics: Aggression; Antipsychotic Agents; Depressive Disorder; Humans; Risperidone

1997
Adding risperidone to selective serotonin reuptake inhibitor improves chronic depression.
    Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:1

    Topics: Adult; Depressive Disorder; Drug Therapy, Combination; Female; Fluoxetine; Humans; Middle Aged; Paro

1998
Risperidone-induced tardive dyskinesia.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:1

    Topics: Antipsychotic Agents; Depressive Disorder; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induce

1998
Risperidone monotherapy for psychotic depression unresponsive to other treatments.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:11

    Topics: Adult; Antipsychotic Agents; Depressive Disorder; Female; Humans; Risperidone; Treatment Outcome

1998
Risperidone monotherapy for mania and depression.
    The American journal of psychiatry, 1999, Volume: 156, Issue:7

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Drug Administration Schedule; Hu

1999
[The new antipsychotic preparation Rispolept (risperidone)].
    Voenno-meditsinskii zhurnal, 1999, Volume: 320, Issue:11

    Topics: Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Dopamine Antagonists; Humans; Obsessive

1999
Atypical antipsychotics for treatment of mixed depression and anxiety.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:5

    Topics: Adult; Antipsychotic Agents; Anxiety Disorders; Benzodiazepines; Comorbidity; Depressive Disorder; D

2000
SIADH with multiple antidepressants in a geriatric patient.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:6

    Topics: Aged; Antidepressive Agents; Antipsychotic Agents; Bupropion; Cyclohexanols; Depressive Disorder; Hu

2000
Tranylcypromine plus risperidone for treatment-refractory major depression.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:4

    Topics: Antipsychotic Agents; Depressive Disorder; Drug Resistance; Female; Humans; Male; Middle Aged; Monoa

2000
Drug induced akathisia, suicidal ideation and its treatment in the elderly.
    International journal of geriatric psychiatry, 2001, Volume: 16, Issue:2

    Topics: Aged; Aged, 80 and over; Akathisia, Drug-Induced; Antipsychotic Agents; Depressive Disorder; Drug Th

2001
The effect of institutional fiscal stress on the use of atypical antipsychotic medications in the treatment of schizophrenia.
    The Journal of nervous and mental disease, 2001, Volume: 189, Issue:6

    Topics: Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Budgets; Clozapine; Comorbidity; Depressiv

2001
Increased plasma concentration of maprotiline by coadministration of risperidone.
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:1

    Topics: Adult; Antipsychotic Agents; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Fema

2002
Are the atypical antipsychotic drugs antidepressants?
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:1

    Topics: Affect; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Depr

2002
Risperidone in the treatment of disorders with a combined psychotic and depressive syndrome--a functional approach.
    Pharmacopsychiatry, 1992, Volume: 25, Issue:5

    Topics: Adult; Aged; Antipsychotic Agents; Depressive Disorder; Female; Humans; Isoxazoles; Male; Middle Age

1992