risperidone has been researched along with Delayed Effects, Prenatal Exposure in 22 studies
Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Risperidone is the first antipsychotic to be approved by Food and Drug Administration (FDA) for treating autism spectrum disorder (ASD)." | 8.31 | The comparative effectiveness of metformin and risperidone in a rat model of valproic acid-induced autism, Potential role for enhanced autophagy. ( Ashour, RH; Atia, AA; Rahman, KM; Ramadan, NM; Zaki, MM, 2023) |
| "Risperidone is the first antipsychotic to be approved by Food and Drug Administration (FDA) for treating autism spectrum disorder (ASD)." | 4.31 | The comparative effectiveness of metformin and risperidone in a rat model of valproic acid-induced autism, Potential role for enhanced autophagy. ( Ashour, RH; Atia, AA; Rahman, KM; Ramadan, NM; Zaki, MM, 2023) |
| "Rodents exposed prenatally to valproic acid (VPA) exhibit autism spectrum disorder (ASD)-like behavioral abnormalities." | 3.85 | Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice. ( Ago, Y; Hara, Y; Hasebe, S; Hashimoto, H; Kawase, H; Matsuda, T; Nakazawa, T; Takuma, K; Tanabe, W; Taruta, A; Tsukada, S, 2017) |
| " Among AAPDs, risperidone (RIS) ranked third after olanzapine (OLZ) and quetiapine (QUE) used during pregnancy, as OLZ is associated to substantial weight gain in adults and offspring." | 3.83 | Effects of prenatal exposure to antipsychotic risperidone on developmental neurotoxicity, apoptotic neurodegeneration and neurobehavioral sequelae in rat offspring. ( Singh, KP; Singh, M; Singh, MK, 2016) |
| "Overall, our data suggest that maternal inflammation may contribute to an increased risk for schizophrenia through mechanisms involving metabolic function and myelin formation and that risperidone in adolescence may prevent or reverse such changes." | 3.81 | Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence. ( Cagney, G; Cannon, M; Cotter, DR; Dicker, P; English, J; Farrelly, L; Föcking, M; Piontkewitz, Y; Wynne, K, 2015) |
| "Perinatal phencyclidine (PCP) administration to rats represents one of the actual animal models of schizophrenia." | 3.78 | Risperidone reverses phencyclidine induced decrease in glutathione levels and alterations of antioxidant defense in rat brain. ( Doknić, M; Jevtić, G; Petronijević, ND; Popović, V; Radonjić, NV; Stojković, T; Velimirović, M, 2012) |
| "Schizophrenia is a severe neuropsychiatric disease associated with substantially higher mortality." | 1.62 | Interacting effects of the MAM model of schizophrenia and antipsychotic treatment: Untargeted proteomics approach in adipose tissue. ( Bienertova-Vasku, J; Horska, K; Hruska, P; Kucera, J; Kuruczova, D; Micale, V; Ruda-Kucerova, J, 2021) |
| "Schizophrenia is associated with behavioral and brain structural abnormalities, of which the hippocampus appears to be one of the most consistent region affected." | 1.43 | Maturation- and sex-sensitive depression of hippocampal excitatory transmission in a rat schizophrenia model. ( Attali, B; Patrich, E; Peretz, A; Piontkewitz, Y; Weiner, I, 2016) |
| "Antipsychotic treatment during pregnancy is indicated when risk of drug exposure to the fetus is outweighed by the untreated psychosis in the mother." | 1.35 | Distinct neurobehavioral consequences of prenatal exposure to sulpiride (SUL) and risperidone (RIS) in rats. ( Hao, Y; Liu, H; Liu, Z; Lu, XH; Ouyang, X; Xu, L; Zuo, J, 2008) |
| "Transient prenatal Vitamin D deficiency is considered a developmental model in schizophrenia research." | 1.33 | Pharmacological treatment to augment hole board habituation in prenatal Vitamin D-deficient rats. ( Becker, A; Grecksch, G, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 14 (63.64) | 24.3611 |
| 2020's | 5 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Elnahas, EM | 1 |
| Abuelezz, SA | 1 |
| Mohamad, MI | 1 |
| Nabil, MM | 1 |
| Abdelraouf, SM | 1 |
| Bahaa, N | 1 |
| Hassan, GAM | 1 |
| Aboul-Fotouh, S | 1 |
| Mishra, A | 1 |
| Singla, R | 1 |
| Kumar, R | 1 |
| Sharma, A | 1 |
| Joshi, R | 1 |
| Sarma, P | 1 |
| Kaur, G | 1 |
| Prajapat, M | 1 |
| Bhatia, A | 1 |
| Medhi, B | 1 |
| Atia, AA | 1 |
| Ashour, RH | 1 |
| Zaki, MM | 1 |
| Rahman, KM | 1 |
| Ramadan, NM | 1 |
| Amini, A | 1 |
| Namvarpour, Z | 1 |
| Namvarpour, M | 1 |
| Raoofi, A | 1 |
| Kucera, J | 1 |
| Horska, K | 1 |
| Hruska, P | 1 |
| Kuruczova, D | 1 |
| Micale, V | 1 |
| Ruda-Kucerova, J | 1 |
| Bienertova-Vasku, J | 1 |
| Farrelly, L | 2 |
| Rosato-Siri, MV | 1 |
| Föcking, M | 2 |
| Codagnone, M | 1 |
| Reines, A | 1 |
| Dicker, P | 2 |
| Wynne, K | 2 |
| Farrell, M | 1 |
| Cannon, M | 2 |
| Cagney, G | 2 |
| Pasquini, JM | 1 |
| Cotter, DR | 2 |
| Hara, Y | 1 |
| Ago, Y | 1 |
| Taruta, A | 1 |
| Hasebe, S | 1 |
| Kawase, H | 1 |
| Tanabe, W | 1 |
| Tsukada, S | 1 |
| Nakazawa, T | 1 |
| Hashimoto, H | 1 |
| Matsuda, T | 1 |
| Takuma, K | 1 |
| Wang, H | 1 |
| Li, JT | 1 |
| Zhang, Y | 1 |
| Liu, R | 1 |
| Wang, XD | 1 |
| Si, TM | 1 |
| Su, YA | 1 |
| Takahashi, K | 1 |
| Nakagawasai, O | 1 |
| Sakuma, W | 1 |
| Nemoto, W | 1 |
| Odaira, T | 1 |
| Lin, JR | 1 |
| Onogi, H | 1 |
| Srivastava, LK | 1 |
| Tan-No, K | 1 |
| Piontkewitz, Y | 3 |
| English, J | 1 |
| Kulkarni, J | 1 |
| Storch, A | 1 |
| Baraniuk, A | 1 |
| Gilbert, H | 1 |
| Gavrilidis, E | 1 |
| Worsley, R | 1 |
| Patrich, E | 1 |
| Peretz, A | 1 |
| Weiner, I | 2 |
| Attali, B | 1 |
| Singh, KP | 3 |
| Singh, MK | 3 |
| Singh, M | 1 |
| Gautam, S | 1 |
| Richtand, NM | 1 |
| Ahlbrand, R | 1 |
| Horn, P | 1 |
| Stanford, K | 1 |
| Bronson, SL | 1 |
| McNamara, RK | 1 |
| Bernstein, HG | 1 |
| Dobrowolny, H | 1 |
| Bogerts, B | 1 |
| Keilhoff, G | 1 |
| Stojković, T | 1 |
| Radonjić, NV | 1 |
| Velimirović, M | 1 |
| Jevtić, G | 1 |
| Popović, V | 1 |
| Doknić, M | 1 |
| Petronijević, ND | 1 |
| Wilson, CA | 1 |
| Terry, AV | 1 |
| Rosengarten, H | 1 |
| Quartermain, D | 1 |
| Becker, A | 1 |
| Grecksch, G | 1 |
| Zuo, J | 1 |
| Liu, Z | 1 |
| Ouyang, X | 1 |
| Liu, H | 1 |
| Hao, Y | 1 |
| Xu, L | 1 |
| Lu, XH | 1 |
1 review available for risperidone and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Antipsychotic use in pregnancy.
Topics: Abnormalities, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Female; Huma | 2015 |
21 other studies available for risperidone and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Novel role of peroxisome proliferator activated receptor-α in valproic acid rat model of autism: Mechanistic study of risperidone and metformin monotherapy versus combination.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Behavior, Animal; Disease Models, Animal; Fema | 2022 |
Granulocyte Colony-Stimulating Factor Improved Core Symptoms of Autism Spectrum Disorder via Modulating Glutamatergic Receptors in the Prefrontal Cortex and Hippocampus of Rat Brains.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autism Spectrum Disorder; Brain; | 2022 |
The comparative effectiveness of metformin and risperidone in a rat model of valproic acid-induced autism, Potential role for enhanced autophagy.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Autophagy; Disease Models, Animal; Female; Hum | 2023 |
Risperidone accelerates bone loss in rats with autistic-like deficits induced by maternal lipopolysaccharides exposure.
Topics: Animals; Animals, Newborn; Autistic Disorder; Behavior, Animal; Biomechanical Phenomena; Bone Resorp | 2020 |
Interacting effects of the MAM model of schizophrenia and antipsychotic treatment: Untargeted proteomics approach in adipose tissue.
Topics: Adipose Tissue; Animals; Antipsychotic Agents; Disease Models, Animal; Female; Haloperidol; Intra-Ab | 2021 |
The Effects of Prenatal Iron Deficiency and Risperidone Treatment on the Rat Frontal Cortex: A Proteomic Analysis.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Female; Frontal Lobe; Iron; | 2017 |
Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice.
Topics: Animals; Aripiprazole; Autism Spectrum Disorder; Dendritic Spines; Disease Models, Animal; Dopamine; | 2017 |
Prenatal Exposure to Antipsychotics Disrupts the Plasticity of Dentate Neurons and Memory in Adult Male Mice.
Topics: Animals; Antipsychotic Agents; Dentate Gyrus; Female; Haloperidol; Male; Memory; Mice, Inbred C57BL; | 2019 |
Prenatal treatment with methylazoxymethanol acetate as a neurodevelopmental disruption model of schizophrenia in mice.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Clozapine; Disease Models, Animal; Fe | 2019 |
Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence.
Topics: Aging; Animals; Antipsychotic Agents; Disease Models, Animal; Female; Male; Myelin Sheath; Prefronta | 2015 |
Maturation- and sex-sensitive depression of hippocampal excitatory transmission in a rat schizophrenia model.
Topics: Animals; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; Hippocampus; Male; Orga | 2016 |
Effects of prenatal exposure to antipsychotic risperidone on developmental neurotoxicity, apoptotic neurodegeneration and neurobehavioral sequelae in rat offspring.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Annexin A5; Antipsychotic Agents; Apop | 2016 |
Effect of in utero exposure to the atypical anti-psychotic risperidone on histopathological features of the rat placenta.
Topics: Animals; Antipsychotic Agents; Female; Fetal Development; Maternal Exposure; Maternal-Fetal Exchange | 2016 |
In utero exposure to atypical antipsychotic drug, risperidone: Effects on fetal neurotoxicity in hippocampal region and cognitive impairment in rat offspring.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antipsychotic Agents; Apoptosis; Avoidance Learning | 2017 |
Effects of risperidone and paliperidone pre-treatment on locomotor response following prenatal immune activation.
Topics: Amphetamine; Animals; Animals, Newborn; Antipsychotic Agents; Central Nervous System Stimulants; Dis | 2011 |
Effects of risperidone treatment in adolescence on hippocampal neurogenesis, parvalbumin expression, and vascularization following prenatal immune activation in rats.
Topics: Animals; Bromodeoxyuridine; Female; Hippocampus; Male; Neurogenesis; Parvalbumins; Poly I-C; Pregnan | 2012 |
Risperidone reverses phencyclidine induced decrease in glutathione levels and alterations of antioxidant defense in rat brain.
Topics: Animals; Antioxidants; Antipsychotic Agents; Brain; Disease Models, Animal; Female; Glutamate-Cystei | 2012 |
Variable maternal stress in rats alters locomotor activity, social behavior, and recognition memory in the adult offspring.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Animals; Antipsychotic Agents; Atomoxetine Hydrochloride; | 2013 |
Effect of prenatal administration of haloperidol, risperidone, quetiapine and olanzapine on spatial learning and retention in adult rats.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Dibenzothiazepines; Drinking; Female; Haloper | 2002 |
Pharmacological treatment to augment hole board habituation in prenatal Vitamin D-deficient rats.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Exploratory Behavior; Female; Glycine; Habituation, | 2006 |
Distinct neurobehavioral consequences of prenatal exposure to sulpiride (SUL) and risperidone (RIS) in rats.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Body Weight; Brain; Conditioning, Psychological; Di | 2008 |