risperidone has been researched along with Complication, Postoperative in 15 studies
Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this randomized, parallel-arm trial was to study the effect of treating subsyndromal delirium with risperidone on the incidence of clinical delirium in elderly patients who underwent on-pump cardiac surgery." | 9.16 | Early treatment with risperidone for subsyndromal delirium after on-pump cardiac surgery in the elderly: a randomized trial. ( Hakim, SM; Naoum, DO; Othman, AI, 2012) |
| "This randomised, double-blinded, placebo-controlled study was primarily aimed to evaluate the potential of risperidone to prevent postoperative delirium following cardiac surgery with cardiopulmonary bypass and the secondary objective was to explore clinical factors associated with postoperative delirium." | 9.12 | Efficacy of risperidone for prevention of postoperative delirium in cardiac surgery. ( Prakanrattana, U; Prapaitrakool, S, 2007) |
| "A 31-year-old patient suffering from schizophrenic psychosis was treated with risperidone, and developed priapism which required surgical intervention and resulted in long-term erectile dysfunction." | 7.74 | Risperidone-induced priapism. ( Makesar, D; Thome, J, 2007) |
| "A 59-year-old man with nonalcoholic steatohepatitis cirrhosis underwent an orthotopic liver transplant and experienced a complicated postoperative course, including a prolonged delirium." | 5.43 | Prolonged Delirium With Catatonia Following Orthotopic Liver Transplant Responsive to Memantine. ( Brown, GD; Muzyk, AJ; Preud'homme, XA, 2016) |
| "The aim of this randomized, parallel-arm trial was to study the effect of treating subsyndromal delirium with risperidone on the incidence of clinical delirium in elderly patients who underwent on-pump cardiac surgery." | 5.16 | Early treatment with risperidone for subsyndromal delirium after on-pump cardiac surgery in the elderly: a randomized trial. ( Hakim, SM; Naoum, DO; Othman, AI, 2012) |
| "This randomised, double-blinded, placebo-controlled study was primarily aimed to evaluate the potential of risperidone to prevent postoperative delirium following cardiac surgery with cardiopulmonary bypass and the secondary objective was to explore clinical factors associated with postoperative delirium." | 5.12 | Efficacy of risperidone for prevention of postoperative delirium in cardiac surgery. ( Prakanrattana, U; Prapaitrakool, S, 2007) |
| "The use of antipsychotics for surgical ICU patients and dexmedetomidine for mechanically ventilated patients as a preventive strategy may reduce the prevalence of delirium in the ICU." | 4.91 | Pharmacologic prevention and treatment of delirium in intensive care patients: A systematic review. ( Bozza, FA; do Brasil, PE; Ely, EW; Salluh, JI; Serafim, RB; Soares, M; Tura, BR, 2015) |
| "A 31-year-old patient suffering from schizophrenic psychosis was treated with risperidone, and developed priapism which required surgical intervention and resulted in long-term erectile dysfunction." | 3.74 | Risperidone-induced priapism. ( Makesar, D; Thome, J, 2007) |
| "Infant delirium is an under-recognized clinical entity in neonatal intensive care, and earlier identification and treatment could minimize morbidities associated with this condition." | 1.46 | A case of infant delirium in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB, 2017) |
| "A 59-year-old man with nonalcoholic steatohepatitis cirrhosis underwent an orthotopic liver transplant and experienced a complicated postoperative course, including a prolonged delirium." | 1.43 | Prolonged Delirium With Catatonia Following Orthotopic Liver Transplant Responsive to Memantine. ( Brown, GD; Muzyk, AJ; Preud'homme, XA, 2016) |
| "Alcohol withdrawal delirium is associated with significant morbidity and mortality." | 1.42 | Alcohol withdrawal delirium manifested by manic symptoms in an elderly patient. ( Chan, HY; Lee, KI, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 9 (60.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Raphael, L | 1 |
| Edna, E | 1 |
| Irina, K | 1 |
| Oded, H | 1 |
| Chan, HY | 1 |
| Lee, KI | 1 |
| Serafim, RB | 1 |
| Bozza, FA | 1 |
| Soares, M | 1 |
| do Brasil, PE | 1 |
| Tura, BR | 1 |
| Ely, EW | 1 |
| Salluh, JI | 1 |
| Brown, GD | 1 |
| Muzyk, AJ | 1 |
| Preud'homme, XA | 1 |
| Edwards, LE | 1 |
| Hutchison, LB | 1 |
| Hornik, CD | 1 |
| Smith, PB | 1 |
| Cotten, CM | 1 |
| Bidegain, M | 1 |
| Vives, S | 1 |
| Batlle, M | 1 |
| Montané, E | 1 |
| Ribera, JM | 1 |
| Bansal, V | 1 |
| Kumar, S | 1 |
| Mowar, A | 1 |
| Sharma, S | 1 |
| Gupta, S | 1 |
| Cao, Y | 1 |
| Zhu, Z | 1 |
| Wang, R | 1 |
| Wang, S | 1 |
| Zhao, J | 1 |
| Saager, L | 1 |
| Sessler, DI | 1 |
| Hakim, SM | 1 |
| Othman, AI | 1 |
| Naoum, DO | 1 |
| Salinas Botrán, A | 1 |
| Urgelés Puértolas, D | 1 |
| Peregrin Abad, E | 1 |
| Raiten, JM | 1 |
| Gutsche, JT | 1 |
| Maeda, K | 1 |
| Shirayama, Y | 1 |
| Nukina, S | 1 |
| Yoshioka, S | 1 |
| Kawahara, R | 1 |
| Makesar, D | 1 |
| Thome, J | 1 |
| Prakanrattana, U | 1 |
| Prapaitrakool, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Virtual Reality Stimulation to Relax and Reduce the Incidence of Delirium[NCT04498585] | 920 participants (Anticipated) | Interventional | 2021-04-14 | Suspended (stopped due to Decreased resources due to COVID-19) | |||
| Usefulness of Bright Light Therapy in the Prevention of Delirium in Patients Undergoing Hematopoietic Stem Cell Transplant (HSCT)[NCT01700816] | 40 participants (Actual) | Interventional | 2012-10-31 | Terminated (stopped due to Low incidence of delirium.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | volume percentage (vol%) of red blood ce (Median) |
|---|---|
| Bright Light Therapy | 28.20 |
| Sham Light | 26.70 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | g/dl (Median) |
|---|---|
| Bright Light Therapy | 9.70 |
| Sham Light | 9.55 |
(NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | days (Median) |
|---|---|
| Bright Light Therapy | 18 |
| Sham Light | 18.5 |
Monday, Wednesday, and Friday assessments will begin after beginning light therapy and include the Delirium Rating Scale-Revised-98 (DRS-98)and Memorial Delirium Assessment Scale (MDAS) (NCT01700816)
Timeframe: From hospital admission until the date of first documented delirium, assessed up to 28 days post-transplant
| Intervention | Participants (Count of Participants) |
|---|---|
| Bright Light Therapy | 1 |
| Sham Light | 0 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | thousand cells/uL (Median) |
|---|---|
| Bright Light Therapy | 39 |
| Sham Light | 33.5 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | M/uL (Median) |
|---|---|
| Bright Light Therapy | 3.21 |
| Sham Light | 2.93 |
"Monday, Wednesday, and Friday assessments of the Memorial Delirium Assessment Scale (MDAS); Patients will receive assessments after beginning light therapy until day 28 post-transplant or discharge, whichever comes first.~10 item scale Items are rated on a four-point scale from 0 (none) to 3 (severe) depending on the level of impairment, rendering a maximum possible score of 30.~A score of 13 has been recommended as a cut-off for establishing the diagnosis of delirium" (NCT01700816)
Timeframe: From first documented episode of delirium until discharge from the hospital, assessed up to 28 days post-transplant
| Intervention | units on a scale (Number) |
|---|---|
| Bright Light Therapy | 18 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | K/uL (Median) |
|---|---|
| Bright Light Therapy | 2.30 |
| Sham Light | 4.75 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | mg/dl (Median) | |
|---|---|---|
| Serum Creatinine | Blood Urea Nitrogen (BUN) | |
| Bright Light Therapy | 0.66 | 9 |
| Sham Light | 0.75 | 8.5 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT (Hematopoietic Stem Cell Transplantation). (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
| Intervention | mmol/L (Median) | |||
|---|---|---|---|---|
| Sodium (Na) | Potassium (K) | Chloride (Cl) | Carbon Dioxide (CO2) | |
| Bright Light Therapy | 139 | 3.6 | 105 | 24.9 |
| Sham Light | 138.0 | 3.80 | 103.0 | 25.10 |
1 review available for risperidone and Complication, Postoperative
| Article | Year |
|---|---|
Pharmacologic prevention and treatment of delirium in intensive care patients: A systematic review.
Topics: Antipsychotic Agents; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Haloperidol; Human | 2015 |
2 trials available for risperidone and Complication, Postoperative
| Article | Year |
|---|---|
Early treatment with risperidone for subsyndromal delirium after on-pump cardiac surgery in the elderly: a randomized trial.
Topics: Aged; Anesthesia, General; Antipsychotic Agents; Basal Ganglia Diseases; Cardiopulmonary Bypass; Cri | 2012 |
Efficacy of risperidone for prevention of postoperative delirium in cardiac surgery.
Topics: Antipsychotic Agents; Coronary Artery Bypass; Delirium; Epidemiologic Methods; Female; Humans; Male; | 2007 |
12 other studies available for risperidone and Complication, Postoperative
| Article | Year |
|---|---|
The Efficacy of Low-Dose Risperidone Treatment for Post-Surgical Delirium in Elderly Orthopedic Patients.
Topics: Aged; Aged, 80 and over; Delirium; Female; Humans; Male; Orthopedics; Postoperative Complications; P | 2023 |
Alcohol withdrawal delirium manifested by manic symptoms in an elderly patient.
Topics: Alcohol Withdrawal Delirium; Alcoholic Intoxication; Bipolar Disorder; Drug Therapy, Combination; He | 2015 |
Prolonged Delirium With Catatonia Following Orthotopic Liver Transplant Responsive to Memantine.
Topics: Catatonia; Delirium; Excitatory Amino Acid Antagonists; Humans; Liver Transplantation; Male; Memanti | 2016 |
A case of infant delirium in the neonatal intensive care unit.
Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acid | 2017 |
[Rhabdomyolysis and renal failure secondary to interaction between simvastatin, ciclosporin A and risperidone in an allogeneic stem cell transplantation patient].
Topics: Acute Kidney Injury; Cyclosporine; Drug Interactions; Drug Therapy, Combination; Humans; Leukemia, M | 2008 |
Postoperative psychosis in an adolescent subsequent to oral surgical outpatient procedure.
Topics: Antipsychotic Agents; Dexamethasone; Female; Glucocorticoids; Humans; Injections, Intravenous; Loraz | 2009 |
Hypersexuality from resection of left occipital arteriovenous malformation.
Topics: Adult; Brain; Brain Chemistry; Cerebral Hemorrhage; Cerebrovascular Circulation; Female; Humans; Int | 2010 |
Targeted prophylaxis of postoperative delirium.
Topics: Antipsychotic Agents; Cardiopulmonary Bypass; Delirium; Female; Humans; Male; Postoperative Complica | 2012 |
[Postpartum psychosis associated with cabergoline].
Topics: Adult; Antipsychotic Agents; Cabergoline; Cesarean Section; Dopamine Agonists; Ergolines; Female; Ha | 2013 |
Use of risperidone in cardiac surgery patients with subsyndromal delirium.
Topics: Antipsychotic Agents; Cardiopulmonary Bypass; Delirium; Female; Humans; Male; Postoperative Complica | 2012 |
Charles Bonnet syndrome with visual hallucinations of childhood experience: successful treatment of 1 patient with risperidone.
Topics: Antipsychotic Agents; Cataract Extraction; Child; Diabetic Retinopathy; Female; Hallucinations; Huma | 2003 |
Risperidone-induced priapism.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Dose-Response Relationship, Drug; Drug Overdose; Erect | 2007 |