Page last updated: 2024-11-03

risperidone and Cognitive Decline

risperidone has been researched along with Cognitive Decline in 17 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Research Excerpts

ExcerptRelevanceReference
"A double-blind, placebo-controlled study involved 75 patients with schizophrenia who randomly received low dose (100 mg/day) or high dose minocycline (200 mg/day) or placebo added to risperidone."9.30The effect of minocycline on amelioration of cognitive deficits and pro-inflammatory cytokines levels in patients with schizophrenia. ( Kosten, TR; Wu, R; Zhang, L; Zhang, XY; Zhao, J; Zheng, H, 2019)
" This study sought to explore the characteristics of white matter structural networks in chronic never-treated schizophrenia and those treated with clozapine or risperidone, and its potential association with cognitive function."7.96Characteristics of White Matter Structural Networks in Chronic Schizophrenia Treated With Clozapine or Risperidone and Those Never Treated. ( Gong, Q; Hu, N; Lencer, R; Li, S; Lui, S; Luo, C; Xiao, Y; Zhang, W, 2020)
"Schizophrenia is a disorder characterized by cognitive impairment and psychotic symptoms that fluctuate over time and can only be mitigated with the chronic administration of antipsychotics."5.72Long-lasting rescue of schizophrenia-relevant cognitive impairments via risperidone-loaded microPlates. ( Bellotti, E; Contarini, G; Decuzzi, P; Drago, F; Geraci, F; Leggio, GM; Papaleo, F; Piazza, C; Torrisi, SA, 2022)
"A double-blind, placebo-controlled study involved 75 patients with schizophrenia who randomly received low dose (100 mg/day) or high dose minocycline (200 mg/day) or placebo added to risperidone."5.30The effect of minocycline on amelioration of cognitive deficits and pro-inflammatory cytokines levels in patients with schizophrenia. ( Kosten, TR; Wu, R; Zhang, L; Zhang, XY; Zhao, J; Zheng, H, 2019)
" This study sought to explore the characteristics of white matter structural networks in chronic never-treated schizophrenia and those treated with clozapine or risperidone, and its potential association with cognitive function."3.96Characteristics of White Matter Structural Networks in Chronic Schizophrenia Treated With Clozapine or Risperidone and Those Never Treated. ( Gong, Q; Hu, N; Lencer, R; Li, S; Lui, S; Luo, C; Xiao, Y; Zhang, W, 2020)
"Thirty-seven clinically stable participants with schizophrenia or schizoaffective disorder, aged 50 years or greater, and having been treated with olanzapine or risperidone monotherapy at the same dose for at least 6 months."3.85Cognition and Dopamine D ( Caravaggio, F; Gerretsen, P; Graff-Guerrero, A; Mamo, DC; Mar, W; Mulsant, BH; Nakajima, S; Pollock, BG; Rajji, TK; Suzuki, T; Uchida, H, 2017)
"Schizophrenia is a disorder characterized by cognitive impairment and psychotic symptoms that fluctuate over time and can only be mitigated with the chronic administration of antipsychotics."1.72Long-lasting rescue of schizophrenia-relevant cognitive impairments via risperidone-loaded microPlates. ( Bellotti, E; Contarini, G; Decuzzi, P; Drago, F; Geraci, F; Leggio, GM; Papaleo, F; Piazza, C; Torrisi, SA, 2022)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (58.82)24.3611
2020's7 (41.18)2.80

Authors

AuthorsStudies
Wu, Z1
Liu, Q1
Zhang, Y1
Guan, X1
Xiu, M1
Zhang, X1
Bellotti, E1
Contarini, G1
Geraci, F1
Torrisi, SA1
Piazza, C1
Drago, F1
Leggio, GM1
Papaleo, F1
Decuzzi, P1
Kelle, I1
Eriman, H1
Erdinc, M1
Uyar, E1
Nguyen, HD1
Jo, WH1
Hoang, NHM1
Kim, MS1
Zhang, L1
Zheng, H1
Wu, R1
Kosten, TR1
Zhang, XY2
Zhao, J1
Ibrahim, I1
Tobar, S1
Fathi, W1
ElSayed, H1
Yassein, A1
Eissa, A1
Elsheshtawy, E1
Elboraei, H1
Shahda, M1
Elwasify, M1
Ibrahim, A1
Chen, K1
Wood, J1
Dickerson, F1
Yolken, RH1
El Chennawi, F1
Gur, R2
El Bahaey, W1
Nimgaonkar, V1
Mansour, H1
Gurler, D1
White, DM2
Kraguljac, NV2
Ver Hoef, L1
Martin, C1
Tennant, B1
Lahti, AC2
Luo, C1
Lencer, R1
Hu, N1
Xiao, Y1
Zhang, W1
Li, S1
Lui, S1
Gong, Q1
Wu, ZW1
Shi, H1
Chen, DC1
Chen, S1
Xiu, MH1
Suzuki, H1
Hibino, H1
Inoue, Y1
Mikami, A1
Matsumoto, H1
Mikami, K1
Boccardi, V1
Baroni, M1
Paolacci, L1
Ercolani, S1
Longo, A1
Giordano, M1
Ruggiero, C1
Mecocci, P1
Rook, JM1
Bertron, JL1
Cho, HP1
Garcia-Barrantes, PM1
Moran, SP1
Maksymetz, JT1
Nance, KD1
Dickerson, JW1
Remke, DH1
Chang, S1
Harp, JM1
Blobaum, AL1
Niswender, CM1
Jones, CK1
Stauffer, SR1
Conn, PJ1
Lindsley, CW1
Cadena, EJ1
Reid, MA1
Jindal, R1
Pixley, RM1
Rajji, TK1
Mulsant, BH1
Nakajima, S1
Caravaggio, F1
Suzuki, T1
Uchida, H1
Gerretsen, P1
Mar, W1
Pollock, BG1
Mamo, DC1
Graff-Guerrero, A1
Singh, KP1
Singh, MK1
Park, CH1
Park, TW1
Yang, JC1
Lee, KH1
Huang, GB1
Tong, Z1
Park, MS1
Chung, YC1
Stone, WS1
Hsi, X1
Giuliano, AJ1
Tan, L1
Zhu, S1
Li, L1
Seidman, LJ1
Tsuang, MT1

Trials

5 trials available for risperidone and Cognitive Decline

ArticleYear
Superoxide Dismutase, BDNF, and Cognitive Improvement in Drug-Naive First-Episode Patients With Schizophrenia: A 12-Week Longitudinal Study.
    The international journal of neuropsychopharmacology, 2022, 02-11, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Antioxidants; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Cognition;

2022
The effect of minocycline on amelioration of cognitive deficits and pro-inflammatory cytokines levels in patients with schizophrenia.
    Schizophrenia research, 2019, Volume: 212

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Antipsychotic Agents; Cognitive Dysfunction; Double-Bli

2019
Randomized controlled trial of adjunctive Valproate for cognitive remediation in early course schizophrenia.
    Journal of psychiatric research, 2019, Volume: 118

    Topics: Adolescent; Adult; Antimanic Agents; Antipsychotic Agents; Cognitive Dysfunction; Double-Blind Metho

2019
No negative symptoms in healthy volunteers after single doses of amisulpride, aripiprazole, and haloperidol: a double-blind placebo-controlled trial.
    International clinical psychopharmacology, 2012, Volume: 27, Issue:2

    Topics: Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Cognitive Dysfunction; Dizziness; Double-Bli

2012
Are neurocognitive, clinical and social dysfunctions in schizotaxia reversible pharmacologically?: Results from the Changsha study.
    Asian journal of psychiatry, 2012, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; China; Cluster Analysis; Cognitive Dysfunction; Double-Blin

2012

Other Studies

12 other studies available for risperidone and Cognitive Decline

ArticleYear
Long-lasting rescue of schizophrenia-relevant cognitive impairments via risperidone-loaded microPlates.
    Drug delivery and translational research, 2022, Volume: 12, Issue:8

    Topics: Animals; Antipsychotic Agents; Cognitive Dysfunction; Delayed-Action Preparations; Dysbindin; Mice;

2022
Risperidone and ethyl pyruvate have protective effects against ketamine-induced cognitive impairments in mice.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:5

    Topics: Animals; Antipsychotic Agents; Cognitive Dysfunction; Ketamine; Mice; Pyruvates; Risperidone

2022
Risperidone ameliorated 1,2-Diacetylbenzene-induced cognitive impairments in mice via activating prolactin signaling pathways.
    International immunopharmacology, 2023, Volume: 115

    Topics: Animals; Cognitive Dysfunction; Glycogen Synthase Kinase 3 beta; Mice; MicroRNAs; Prolactin; Risperi

2023
Neural Signatures of Memory Encoding in Schizophrenia Are Modulated by Antipsychotic Treatment.
    Neuropsychobiology, 2021, Volume: 80, Issue:1

    Topics: Adult; Antipsychotic Agents; Cognitive Dysfunction; Default Mode Network; Female; Glutamic Acid; Glu

2021
Characteristics of White Matter Structural Networks in Chronic Schizophrenia Treated With Clozapine or Risperidone and Those Never Treated.
    The international journal of neuropsychopharmacology, 2020, 12-29, Volume: 23, Issue:12

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Clozapine; Cognitive Dysfunction; Diffusion Tensor Ima

2020
BDNF serum levels and cognitive improvement in drug-naive first episode patients with schizophrenia: A prospective 12-week longitudinal study.
    Psychoneuroendocrinology, 2020, Volume: 122

    Topics: Adult; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Cognition; Cognition Disorders; Cogn

2020
Benefit of extending the dosing interval of long-acting antipsychotic injections in elderly schizophrenics with cognitive dysfunction.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2017, Volume: 17, Issue:6

    Topics: Aged; Antipsychotic Agents; Cognitive Dysfunction; Dose-Response Relationship, Drug; Drug Administra

2017
Anticholinergic Burden and Functional Status in Older People with Cognitive Impairment: Results from the Regal Project.
    The journal of nutrition, health & aging, 2017, Volume: 21, Issue:4

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Cholinergic Antagonists; Cog

2017
A Novel M
    ACS chemical neuroscience, 2018, 09-19, Volume: 9, Issue:9

    Topics: Allosteric Regulation; Animals; Antipsychotic Agents; CHO Cells; Cognition; Cognitive Dysfunction; C

2018
Cognitive control network dysconnectivity and response to antipsychotic treatment in schizophrenia.
    Schizophrenia research, 2019, Volume: 204

    Topics: Adult; Antipsychotic Agents; Cognitive Dysfunction; Connectome; Executive Function; Female; Follow-U

2019
Cognition and Dopamine D
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2017, Volume: 25, Issue:1

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Cognitive Dysfunction; Corpus Striatum; Female; Humans;

2017
In utero exposure to atypical antipsychotic drug, risperidone: Effects on fetal neurotoxicity in hippocampal region and cognitive impairment in rat offspring.
    Progress in neuro-psychopharmacology & biological psychiatry, 2017, 04-03, Volume: 75

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antipsychotic Agents; Apoptosis; Avoidance Learning

2017