Page last updated: 2024-11-03

risperidone and Callous-Unemotional Traits

risperidone has been researched along with Callous-Unemotional Traits in 30 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Research Excerpts

ExcerptRelevanceReference
"In this study, we aimed to expand on our prior research into the relative efficacy of combining parent training, stimulant medication, and placebo (Basic therapy) versus parent training, stimulant, and risperidone (Augmented therapy) by examining treatment effects for attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), and conduct disorder (CD) symptoms and peer aggression, symptom-induced impairment, and informant discrepancy."9.19Risperidone added to parent training and stimulant medication: effects on attention-deficit/hyperactivity disorder, oppositional defiant disorder, conduct disorder, and peer aggression. ( Aman, MG; Arnold, LE; Austin, AB; Baker, JL; Bangalore, SS; Brown, NV; Buchan-Page, KA; Bukstein, OG; Butter, EM; Farmer, CA; Findling, RL; Gadow, KD; Grondhuis, SN; Hurt, EA; Kipp, HL; Li, X; McNamara, NK; Molina, BS; Rice, RR; Rundberg-Rivera, EV; Schneider, J; Sprafkin, J, 2014)
"Risperidone has been found efficacious for decreasing severe tantrums, aggression, and self-injurious behavior in children and adolescents with autistic disorder (autism)."9.11Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology. ( Aman, MG; Arnold, LE; Chuang, SZ; Davies, M; Ghuman, JK; Gonzalez, NM; Hollway, J; Koenig, K; Martin, A; McCracken, JT; McDougle, CJ; McGough, JJ; Posey, DJ; Ritz, L; Scahill, L; Shah, B; Swiezy, NB; Tierney, E; Vitiello, B, 2005)
"The present study aimed to analyse the effect of risperidone on a priori defined core aggression items."9.11Risperidone reduces aggression in boys with a disruptive behaviour disorder and below average intelligence quotient: analysis of two placebo-controlled randomized trials. ( Aman, MG; Armenteros, JL; Binder, CE; Hew, H; Kusumakar, V; LeBlanc, JC; Wang, JS, 2005)
"Risperidone was superior to placebo in ameliorating aggression on most measures."9.09A double-blind pilot study of risperidone in the treatment of conduct disorder. ( Blumer, JL; Branicky, LA; Findling, RL; Lemon, E; McNamara, NK; Schluchter, MD, 2000)
" Here, authors report on an interesting case of risperidone-induced pancreatitis in a child with ADHD comorbid with conduct disorder."8.12Probable Risperidone-Associated Acute Pancreatitis in a Child with ADHD. ( Alamiri, B; Naguy, A; Roshdy, R, 2022)
"Risperidone is a widely used, second-generation antipsychotic approved for treating schizophrenia as well as for treating aggression in children and adolescents with mental retardation."7.85Mild Hypothermia in a Child with Low-Dose Risperidone. ( Denzer, C; Freudenmann, RW; Gahr, M; Grau, K; Plener, PL, 2017)
" Safety measures included body mass index, serum prolactin, extrapyramidal adverse effects, and electrocardiogram."6.80Efficacy and Safety of Risperidone and Quetiapine in Adolescents With Bipolar II Disorder Comorbid With Conduct Disorder. ( Masi, G; Milone, A; Pisano, S; Stawinoga, A; Veltri, S, 2015)
" The results from the literature underline the necessity of caution and patient monitoring when risperidone dosing is modified during methylphenidate therapy."6.72Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance. ( Burden, AM; Stämpfli, D; Weiler, S, 2021)
"In this study, we aimed to expand on our prior research into the relative efficacy of combining parent training, stimulant medication, and placebo (Basic therapy) versus parent training, stimulant, and risperidone (Augmented therapy) by examining treatment effects for attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), and conduct disorder (CD) symptoms and peer aggression, symptom-induced impairment, and informant discrepancy."5.19Risperidone added to parent training and stimulant medication: effects on attention-deficit/hyperactivity disorder, oppositional defiant disorder, conduct disorder, and peer aggression. ( Aman, MG; Arnold, LE; Austin, AB; Baker, JL; Bangalore, SS; Brown, NV; Buchan-Page, KA; Bukstein, OG; Butter, EM; Farmer, CA; Findling, RL; Gadow, KD; Grondhuis, SN; Hurt, EA; Kipp, HL; Li, X; McNamara, NK; Molina, BS; Rice, RR; Rundberg-Rivera, EV; Schneider, J; Sprafkin, J, 2014)
"Risperidone has been found efficacious for decreasing severe tantrums, aggression, and self-injurious behavior in children and adolescents with autistic disorder (autism)."5.11Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology. ( Aman, MG; Arnold, LE; Chuang, SZ; Davies, M; Ghuman, JK; Gonzalez, NM; Hollway, J; Koenig, K; Martin, A; McCracken, JT; McDougle, CJ; McGough, JJ; Posey, DJ; Ritz, L; Scahill, L; Shah, B; Swiezy, NB; Tierney, E; Vitiello, B, 2005)
"The present study aimed to analyse the effect of risperidone on a priori defined core aggression items."5.11Risperidone reduces aggression in boys with a disruptive behaviour disorder and below average intelligence quotient: analysis of two placebo-controlled randomized trials. ( Aman, MG; Armenteros, JL; Binder, CE; Hew, H; Kusumakar, V; LeBlanc, JC; Wang, JS, 2005)
"To determine whether risperidone is effective in reducing symptoms of disruptive behaviors (such as aggression, impulsivity, defiance of authority figures, and property destruction) associated with conduct disorder, oppositional defiant disorder, and disruptive behavior disorder-not otherwise specified in children with subaverage IQs."5.10Effects of risperidone on conduct and disruptive behavior disorders in children with subaverage IQs. ( Aman, M; Binder, C; Carroll, A; Fisman, S; Snyder, R; Turgay, A, 2002)
"Risperidone was superior to placebo in ameliorating aggression on most measures."5.09A double-blind pilot study of risperidone in the treatment of conduct disorder. ( Blumer, JL; Branicky, LA; Findling, RL; Lemon, E; McNamara, NK; Schluchter, MD, 2000)
"There is some evidence that in the short term risperidone may reduce aggression and conduct problems in children and youths with disruptive behaviour disorders There is also evidence that this intervention is associated with significant weight gain."4.95Atypical antipsychotics for disruptive behaviour disorders in children and youths. ( Hetrick, SE; Loy, JH; Merry, SN; Stasiak, K, 2017)
"There is some limited evidence of efficacy of risperidone reducing aggression and conduct problems in children aged 5 to 18 with disruptive behaviour disorders in the short term."4.88Atypical antipsychotics for disruptive behaviour disorders in children and youths. ( Hetrick, SE; Loy, JH; Merry, SN; Stasiak, K, 2012)
" Here, authors report on an interesting case of risperidone-induced pancreatitis in a child with ADHD comorbid with conduct disorder."4.12Probable Risperidone-Associated Acute Pancreatitis in a Child with ADHD. ( Alamiri, B; Naguy, A; Roshdy, R, 2022)
"Risperidone is a widely used, second-generation antipsychotic approved for treating schizophrenia as well as for treating aggression in children and adolescents with mental retardation."3.85Mild Hypothermia in a Child with Low-Dose Risperidone. ( Denzer, C; Freudenmann, RW; Gahr, M; Grau, K; Plener, PL, 2017)
" The aims of this study were to investigate the effectiveness and adverse effects of LAIR in children and adolescents with conduct disorder, bipolar disorder, and schizophrenia."2.84Effectiveness, Adverse Effects and Drug Compliance of Long-Acting Injectable Risperidone in Children and Adolescents. ( Ceylan, MF; Cop, E; Erdogan, B; Tural Hesapcioglu, S, 2017)
" Safety measures included body mass index, serum prolactin, extrapyramidal adverse effects, and electrocardiogram."2.80Efficacy and Safety of Risperidone and Quetiapine in Adolescents With Bipolar II Disorder Comorbid With Conduct Disorder. ( Masi, G; Milone, A; Pisano, S; Stawinoga, A; Veltri, S, 2015)
" The results from the literature underline the necessity of caution and patient monitoring when risperidone dosing is modified during methylphenidate therapy."2.72Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance. ( Burden, AM; Stämpfli, D; Weiler, S, 2021)
" Safety and tolerability were good overall, with the number of adverse events (AEs) decreasing in the extension trial, compared to the original trial."2.72Long-term use of risperidone in children with disruptive behavior disorders and subaverage intelligence: efficacy, safety, and tolerability. ( Augustyns, I; Croonenberghs, J; Eerdekens, M; Reyes, M, 2006)
"Risperidone was also associated with significantly greater improvement than placebo on all other Nisonger Child Behavior Rating Form subscales at endpoint, as well as on the Aberrant Behavior Checklist subscales for irritability, lethargy/social withdrawal, and hyperactivity; the Behavior Problems Inventory aggressive/destructive behavior subscale; a visual analogue scale of the most troublesome symptom; and the Clinical Global Impression change score."2.70Double-blind, placebo-controlled study of risperidone for the treatment of disruptive behaviors in children with subaverage intelligence. ( Aman, MG; De Smedt, G; Derivan, A; Findling, RL; Lyons, B, 2002)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (36.67)29.6817
2010's15 (50.00)24.3611
2020's4 (13.33)2.80

Authors

AuthorsStudies
Wozniak, J1
DiSalvo, M1
Farrell, A1
Yule, A1
Joshi, G1
Cook, E1
Faraone, SV1
Biederman, J1
Hodgins, GE1
Winsor, K1
Barnhill, J1
Naguy, A1
Roshdy, R1
Alamiri, B1
Stämpfli, D1
Weiler, S1
Burden, AM1
Ceylan, MF1
Erdogan, B1
Tural Hesapcioglu, S1
Cop, E1
Loy, JH2
Merry, SN2
Hetrick, SE2
Stasiak, K2
Gnanavel, S1
Joseph, HM1
Farmer, C1
Kipp, H1
Kolko, D1
Aman, M2
McGinley, J1
Arnold, LE3
Gadow, KD2
Findling, RL5
Molina, BSG1
Khan, S1
Down, J1
Aouira, N1
Bor, W1
Haywood, A1
Littlewood, R1
Heussler, H1
McDermott, B1
Glennon, J1
Purper-Ouakil, D1
Bakker, M1
Zuddas, A1
Hoekstra, P1
Schulze, U1
Castro-Fornieles, J1
Santosh, PJ1
Arango, C1
Kölch, M1
Coghill, D1
Flamarique, I1
Penzol, MJ1
Wan, M1
Murray, M1
Wong, IC1
Danckaerts, M1
Bonnot, O1
Falissard, B1
Masi, G2
Fegert, JM1
Vicari, S1
Carucci, S1
Dittmann, RW1
Buitelaar, JK1
Javelot, H1
Glay-Ribau, C1
Ligier, F1
Weiner, L1
Didelot, N1
Messaoudi, M1
Socha, M1
Body-Lawson, F1
Kabuth, B1
Jensen, PS1
Molina, BS1
Bukstein, OG1
Brown, NV1
McNamara, NK2
Rundberg-Rivera, EV1
Li, X1
Kipp, HL1
Schneider, J1
Farmer, CA1
Baker, JL1
Sprafkin, J1
Rice, RR1
Bangalore, SS1
Butter, EM1
Buchan-Page, KA1
Hurt, EA1
Austin, AB1
Grondhuis, SN1
Aman, MG5
Connolly, JG1
Toomey, TJ1
Schneeweiss, MC1
Milone, A1
Stawinoga, A1
Veltri, S1
Pisano, S1
Moreton, A1
Imran, S1
Grau, K1
Plener, PL1
Gahr, M1
Denzer, C1
Freudenmann, RW1
Kálmán, J1
Kálmán, S1
Pákáski, M1
Rothermel, B1
Poustka, L1
Banaschewski, T1
Becker, K1
De Smedt, G2
Derivan, A1
Lyons, B1
Snyder, R1
Turgay, A1
Binder, C2
Fisman, S1
Carroll, A1
Kusumakar, V2
Daneman, D1
Moshang, T1
McDougle, CJ1
Scahill, L1
McCracken, JT1
Tierney, E1
Davies, M1
Posey, DJ1
Martin, A1
Ghuman, JK1
Shah, B1
Chuang, SZ1
Swiezy, NB1
Gonzalez, NM1
Hollway, J1
Koenig, K1
McGough, JJ1
Ritz, L1
Vitiello, B1
Deberdt, WG1
Dysken, MW1
Rappaport, SA1
Feldman, PD1
Young, CA1
Hay, DP1
Lehman, DL1
Dossenbach, M1
Degenhardt, EK1
Breier, A1
LeBlanc, JC1
Binder, CE1
Armenteros, JL1
Wang, JS1
Hew, H1
Reyes, M1
Croonenberghs, J1
Augustyns, I1
Eerdekens, M1
Pandina, GJ1
Bilder, R1
Harvey, PD1
Keefe, RS1
Gharabawi, G1
Sabuncuoglu, O1
Branicky, LA1
Schluchter, MD1
Lemon, E1
Blumer, JL1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Stimulant and Risperidone in Children With Severe Physical Aggression[NCT00796302]Phase 4168 participants (Actual)Interventional2008-08-31Completed
The Investigation of the Impact of Atypical Antipsychotics on Brain Functioning in Youths With Conduct Disorder[NCT01867398]12 participants (Actual)Observational2013-04-29Terminated
The Safety And Efficacy Of Risperidone Versus Placebo In Conduct Disorder and Other Disruptive Behavior Disorders In Mild, Moderate And Borderline Mentally Retarded Children Aged 5 To 12 Years[NCT00266552]Phase 3118 participants (Actual)InterventionalCompleted
The Safety And Efficacy Of Risperidone Versus Placebo In Conduct Disorder In Mild, Moderate And Borderline Mentally Retarded Children Aged 5 To 12 Years[NCT00250354]Phase 3110 participants (Actual)Interventional1997-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Antisocial Behavior Scale - Reactive Aggression Subscale

The Antisocial Behavior Scale (ABS) is a 28-item scale that contains 10 Proactive Aggression items and six Reactive Aggression items. Each item is rated on a 3-point scale, ranging from 1 (Never) to 3 (Very often). Thus, scores on the Reactive Aggression subscale can range from 6 through 18; with higher scores indicating more reactive aggression. (NCT00796302)
Timeframe: Measured at baseline and Week 9

,
Interventionunits on a scale (Mean)
BaselineWeek 9
Augmented (Stimulant + PMT + Risperidone)15.511.0
Basic (Stimulant + PMT + Placebo)15.912.3

Clinical Global Impressions Scale for Improvement

"Using this clinician rating scale the patient's improvement is scored on a 7-point scale which ranges from very much improved (1), through no change (4), to very much worse (7). This scale was used at baseline and Weeks 1, 2, 3, 4, 5, 6, 7, 8, & 9. Only endpoint (week 9 or subject's last visit) Clinical Global Impressions Scale for Improvement scores are reported below." (NCT00796302)
Timeframe: Measured at endpoint visit

,
Interventionparticipants (Number)
Much or very much improved at endpointMinimally improved at endpointUnchanged or worse at endpoint
Augmented (Stimulant + PMT + Risperidone)63116
Basic (Stimulant + PMT + Placebo)58223

Clinical Global Impressions Scale for Severity of Illness

Using this clinician rating scale the severity of the illness is scored from 1= normal to 7= extremely ill. This scale was used at baseline and Weeks 1, 2, 3, 4, 5, 6, 7, 8, & 9. Only endpoint (week 9 or subject's last visit) Clinical Global Impressions Scale for Severity of Illness scores are reported below. (NCT00796302)
Timeframe: Measured at endpoint visit

,
Interventionparticipants (Number)
Normal/Borderline/Mildly ill at endpointModerately/Markedly/Severely ill at endpoint
Augmented (Stimulant + PMT + Risperidone)5622
Basic (Stimulant + PMT + Placebo)4934

NCBRF-TIQ D-Total Score

"Parent ratings of aggression and hostility on the Nisonger Child Behavior Rating Form-Typical IQ (NCBRF-TIQ) D-Total Score. The NCBRF provides 1 prosocial subscale (Positive/Social) and 6 problem behavior subscales (Conduct Problem, Oppositional Behavior, Hyperactive, Inattentive, Overly Sensitive, and Withdrawn/Dysphoric). The NCBRF has excellent internal consistency, distinguishes between controls and subjects with DBDs. Conduct Problem and Oppositional Behavior subscales map closely to DSM-IV-TR symptoms of CD and ODD; they were scored together to form a variable called the D-Total.~For the NCBRF D-Total, higher scores reflect worse behavior. Each subscale is scored by taking the rating (0 [did not occur or was not a problem] to 3 [occurred a lot or was a very severe problem]) for all component items. The D-Total score was computed by adding the 6 scores from the Oppositional subscale and the 10 items from the Conduct Problem subscale. Thus D-Total scores could range from 0-69." (NCT00796302)
Timeframe: Measured at baseline and Weeks 3, 4, 5, 6, 7, 8, 9

,
Interventionunits on a scale (Mean)
BaselineWeek 3Week 4Week 5Week 6Week 7Week 8Week 9
Augmented (Stimulant + PMT + Risperidone)42.125.917.112.113.813.011.710.7
Basic (Stimulant + PMT + Placebo)43.524.922.420.120.716.817.817.8

Reviews

6 reviews available for risperidone and Callous-Unemotional Traits

ArticleYear
Pharmacotherapy of Disruptive Behaviors in Children with Intellectual Disabilities.
    Paediatric drugs, 2022, Volume: 24, Issue:5

    Topics: Aggression; Attention Deficit and Disruptive Behavior Disorders; Child; Conduct Disorder; Humans; In

2022
Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance.
    European child & adolescent psychiatry, 2021, Volume: 30, Issue:7

    Topics: Attention Deficit Disorder with Hyperactivity; Combined Modality Therapy; Comorbidity; Conduct Disor

2021
Atypical antipsychotics for disruptive behaviour disorders in children and youths.
    The Cochrane database of systematic reviews, 2017, 08-09, Volume: 8

    Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety Disorders; Attention Deficit and Disruptive Be

2017
Current pharmacotherapy options for conduct disorders in adolescents and children.
    Expert opinion on pharmacotherapy, 2019, Volume: 20, Issue:5

    Topics: Adolescent; Aggression; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Central Nervous Sys

2019
[Recognition and treatment of behavioral and psychological symptoms of dementias: lessons from the CATIE-AD study].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008, Volume: 10, Issue:4

    Topics: Affect; Aggression; Antipsychotic Agents; Brain; Caregivers; Conduct Disorder; Dementia; Diagnosis,

2008
Atypical antipsychotics for disruptive behaviour disorders in children and youths.
    The Cochrane database of systematic reviews, 2012, Sep-12, Issue:9

    Topics: Adolescent; Aggression; Antipsychotic Agents; Anxiety Disorders; Attention Deficit and Disruptive Be

2012

Trials

12 trials available for risperidone and Callous-Unemotional Traits

ArticleYear
Effectiveness, Adverse Effects and Drug Compliance of Long-Acting Injectable Risperidone in Children and Adolescents.
    Clinical drug investigation, 2017, Volume: 37, Issue:10

    Topics: Adolescent; Antipsychotic Agents; Bipolar Disorder; Child; Conduct Disorder; Delayed-Action Preparat

2017
Attendance and Engagement in Parent Training Predict Child Behavioral Outcomes in Children Pharmacologically Treated for Attention-Deficit/Hyperactivity Disorder and Severe Aggression.
    Journal of child and adolescent psychopharmacology, 2019, Volume: 29, Issue:2

    Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Attention Def

2019
Risperidone added to parent training and stimulant medication: effects on attention-deficit/hyperactivity disorder, oppositional defiant disorder, conduct disorder, and peer aggression.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2014, Volume: 53, Issue:9

    Topics: Aggression; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys

2014
Efficacy and Safety of Risperidone and Quetiapine in Adolescents With Bipolar II Disorder Comorbid With Conduct Disorder.
    Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:5

    Topics: Adolescent; Antipsychotic Agents; Bipolar Disorder; Body Mass Index; Conduct Disorder; Female; Human

2015
Double-blind, placebo-controlled study of risperidone for the treatment of disruptive behaviors in children with subaverage intelligence.
    The American journal of psychiatry, 2002, Volume: 159, Issue:8

    Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Comorb

2002
Double-blind, placebo-controlled study of risperidone for the treatment of disruptive behaviors in children with subaverage intelligence.
    The American journal of psychiatry, 2002, Volume: 159, Issue:8

    Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Comorb

2002
Double-blind, placebo-controlled study of risperidone for the treatment of disruptive behaviors in children with subaverage intelligence.
    The American journal of psychiatry, 2002, Volume: 159, Issue:8

    Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Comorb

2002
Double-blind, placebo-controlled study of risperidone for the treatment of disruptive behaviors in children with subaverage intelligence.
    The American journal of psychiatry, 2002, Volume: 159, Issue:8

    Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Comorb

2002
Effects of risperidone on conduct and disruptive behavior disorders in children with subaverage IQs.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2002, Volume: 41, Issue:9

    Topics: Analysis of Variance; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Chi

2002
Prolactin levels during long-term risperidone treatment in children and adolescents.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:11

    Topics: Adolescent; Antipsychotic Agents; Child; Child Behavior Disorders; Child, Preschool; Conduct Disorde

2003
Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology.
    The American journal of psychiatry, 2005, Volume: 162, Issue:6

    Topics: Adolescent; Antipsychotic Agents; Autistic Disorder; Child; Communication Disorders; Conduct Disorde

2005
Comparison of olanzapine and risperidone in the treatment of psychosis and associated behavioral disturbances in patients with dementia.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005, Volume: 13, Issue:8

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiaze

2005
Risperidone reduces aggression in boys with a disruptive behaviour disorder and below average intelligence quotient: analysis of two placebo-controlled randomized trials.
    International clinical psychopharmacology, 2005, Volume: 20, Issue:5

    Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Child,

2005
Long-term use of risperidone in children with disruptive behavior disorders and subaverage intelligence: efficacy, safety, and tolerability.
    Journal of child and adolescent psychopharmacology, 2006, Volume: 16, Issue:3

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Behavior; Child; Co

2006
A double-blind pilot study of risperidone in the treatment of conduct disorder.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2000, Volume: 39, Issue:4

    Topics: Adolescent; Aggression; Antipsychotic Agents; Child; Conduct Disorder; Dose-Response Relationship, D

2000

Other Studies

12 other studies available for risperidone and Callous-Unemotional Traits

ArticleYear
Can pediatric bipolar disorder be successfully treated when comorbid with conduct disorder? A secondary analysis of clinical trials of risperidone, olanzapine, quetiapine, ziprasidone, and aripiprazole.
    Journal of psychopharmacology (Oxford, England), 2022, Volume: 36, Issue:5

    Topics: Adolescent; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder;

2022
Probable Risperidone-Associated Acute Pancreatitis in a Child with ADHD.
    Psychopharmacology bulletin, 2022, 10-27, Volume: 52, Issue:4

    Topics: Acute Disease; Attention Deficit Disorder with Hyperactivity; Child; Conduct Disorder; Humans; Pancr

2022
Tardive Oculogyric Crisis With Low-Dose Antipsychotic in an Adolescent: A Case Report.
    The primary care companion for CNS disorders, 2018, Nov-22, Volume: 20, Issue:6

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys

2018
Paediatric European Risperidone Studies (PERS): context, rationale, objectives, strategy, and challenges.
    European child & adolescent psychiatry, 2014, Volume: 23, Issue:12

    Topics: Adolescent; Antipsychotic Agents; Child; Clinical Trials as Topic; Conduct Disorder; Europe; Humans;

2014
Methylphenidate-risperidone combination in child psychiatry: A retrospective analysis of 44 cases.
    Annales pharmaceutiques francaises, 2014, Volume: 72, Issue:3

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Psychiatry; Conduct Disorder

2014
TOSCA: no longer just an opera.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2014, Volume: 53, Issue:9

    Topics: Aggression; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys

2014
Metabolic monitoring for youths initiating use of second-generation antipsychotics, 2003-2011.
    Psychiatric services (Washington, D.C.), 2015, Volume: 66, Issue:6

    Topics: Adolescent; Affective Disorders, Psychotic; Antipsychotic Agents; Anxiety Disorders; Aripiprazole; B

2015
A role for risperidone in the treatment of communication disorder and comorbid mental health problems?
    BMJ case reports, 2015, Nov-25, Volume: 2015

    Topics: Adolescent; Affective Symptoms; Antipsychotic Agents; Conduct Disorder; Diagnosis, Differential; Fem

2015
Mild Hypothermia in a Child with Low-Dose Risperidone.
    Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie, 2017, Volume: 45, Issue:4

    Topics: Aggression; Attention Deficit Disorder with Hyperactivity; Child; Cognitive Behavioral Therapy; Comb

2017
[Bipolar disorders as co-morbidity in childhood and adolescence--underdiagnosed or overinterpreted? Therapy of a 14-year-old boy with hyperkinetic conduct disorder and hypomania].
    Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie, 2010, Volume: 38, Issue:2

    Topics: Adolescent; Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; A

2010
Risperidone and cognitive function in children with disruptive behavior disorders.
    Biological psychiatry, 2007, Aug-01, Volume: 62, Issue:3

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Child; Child,

2007
Risperidone-to-methylphenidate switch reaction in children: three cases.
    Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:2

    Topics: Adolescent; Akathisia, Drug-Induced; Antipsychotic Agents; Attention Deficit and Disruptive Behavior

2007