risperidone has been researched along with Breast Neoplasms in 4 studies
Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After adjusting for age, there was no increased risk for breast cancer among risperidone users compared to patients exposed to another atypical antipsychotic (HR 0." | 7.85 | Risk of breast cancer in risperidone users: A nationwide cohort study. ( Bahmanyar, S; Brandt, L; Kieler, H; Qiu, H; Reutfors, J; Wang, Y; Wingård, L, 2017) |
| "Tamoxifen has long been used and still is the most commonly used endocrine therapy for treatment of both early and advanced estrogen receptor-positive breast cancer in pre- and post-menopause women." | 7.80 | Combination treatment of tamoxifen with risperidone in breast cancer. ( Chen, DR; Lin, HY; Wu, HM; Yeh, WL, 2014) |
| "We found that the two hyperprolactinemia-inducing antipsychotics, risperidone and pimozide, prompted precancerous lesions to progress to cancer while aripiprazole, which did not cause hyperprolactinemia, did not." | 3.88 | Hyperprolactinemia-inducing antipsychotics increase breast cancer risk by activating JAK-STAT5 in precancerous lesions. ( Bu, W; Camacho, L; Garcia, S; Hein, S; Hilsenbeck, SG; Johnston, AN; Kapali, J; Li, Y; Nagi, C; Nangia, J; Podsypanina, K; Qin, L; Xue, L, 2018) |
| " After adjusting for age, there was no increased risk for breast cancer among risperidone users compared to patients exposed to another atypical antipsychotic (HR 0." | 3.85 | Risk of breast cancer in risperidone users: A nationwide cohort study. ( Bahmanyar, S; Brandt, L; Kieler, H; Qiu, H; Reutfors, J; Wang, Y; Wingård, L, 2017) |
| "Tamoxifen has long been used and still is the most commonly used endocrine therapy for treatment of both early and advanced estrogen receptor-positive breast cancer in pre- and post-menopause women." | 3.80 | Combination treatment of tamoxifen with risperidone in breast cancer. ( Chen, DR; Lin, HY; Wu, HM; Yeh, WL, 2014) |
| " In the two studies, estimated increased risks of breast cancer were disconcertingly high (up to 62%), but a third recent study found only a weak dose-response association." | 1.91 | Association between long-term use of prolactin-elevating antipsychotics in women and the risk of breast cancer: What are the clinical implications? ( Copolov, DL; Hope, JD; Keks, NA, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hope, JD | 1 |
| Keks, NA | 1 |
| Copolov, DL | 1 |
| Johnston, AN | 1 |
| Bu, W | 1 |
| Hein, S | 1 |
| Garcia, S | 1 |
| Camacho, L | 1 |
| Xue, L | 1 |
| Qin, L | 1 |
| Nagi, C | 1 |
| Hilsenbeck, SG | 1 |
| Kapali, J | 1 |
| Podsypanina, K | 1 |
| Nangia, J | 1 |
| Li, Y | 1 |
| Yeh, WL | 1 |
| Lin, HY | 1 |
| Wu, HM | 1 |
| Chen, DR | 1 |
| Reutfors, J | 1 |
| Wingård, L | 1 |
| Brandt, L | 1 |
| Wang, Y | 1 |
| Qiu, H | 1 |
| Kieler, H | 1 |
| Bahmanyar, S | 1 |
4 other studies available for risperidone and Breast Neoplasms
| Article | Year |
|---|---|
Association between long-term use of prolactin-elevating antipsychotics in women and the risk of breast cancer: What are the clinical implications?
Topics: Antipsychotic Agents; Breast Neoplasms; Female; Humans; Prolactin; Risperidone; Schizophrenia | 2023 |
Hyperprolactinemia-inducing antipsychotics increase breast cancer risk by activating JAK-STAT5 in precancerous lesions.
Topics: Animals; Antipsychotic Agents; Apoptosis; Breast; Breast Neoplasms; Cell Differentiation; Female; Hu | 2018 |
Combination treatment of tamoxifen with risperidone in breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Drug Therapy, Combination; Endoplasmic Re | 2014 |
Risk of breast cancer in risperidone users: A nationwide cohort study.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Antipsychotic Agents; Breast Neoplasms | 2017 |