Page last updated: 2024-11-03

risperidone and Borderline Personality Disorder

risperidone has been researched along with Borderline Personality Disorder in 9 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Borderline Personality Disorder: A personality disorder marked by a pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts. (DSM-IV)

Research Excerpts

ExcerptRelevanceReference
"The association between 5 ANKK1, 54 DRD2, and 11 HTR2C SNPs and weight change during 8 weeks of olanzapine treatment was assessed in 4 pooled studies of 205 white patients with diagnoses other than schizophrenia who were generally likely to have had limited previous antipsychotic exposure."9.16Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia. ( Bishop, JR; Conley, RR; Ellingrod, VL; Fijal, BA; Houston, JP; Kohler, J; Ostbye, KM; Poole Hoffmann, V; Zhao, F, 2012)
"Of the various Axis II disorders, borderline personality disorder (BPD) is among the more critical to treat."6.70Treatment of borderline personality disorder with risperidone. ( Bogetto, F; Cocuzza, E; Marchiaro, L; Rocca, P, 2002)
"The association between 5 ANKK1, 54 DRD2, and 11 HTR2C SNPs and weight change during 8 weeks of olanzapine treatment was assessed in 4 pooled studies of 205 white patients with diagnoses other than schizophrenia who were generally likely to have had limited previous antipsychotic exposure."5.16Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia. ( Bishop, JR; Conley, RR; Ellingrod, VL; Fijal, BA; Houston, JP; Kohler, J; Ostbye, KM; Poole Hoffmann, V; Zhao, F, 2012)
"Of the various Axis II disorders, borderline personality disorder (BPD) is among the more critical to treat."2.70Treatment of borderline personality disorder with risperidone. ( Bogetto, F; Cocuzza, E; Marchiaro, L; Rocca, P, 2002)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's5 (55.56)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Houston, JP1
Kohler, J1
Bishop, JR1
Ellingrod, VL1
Ostbye, KM1
Zhao, F1
Conley, RR1
Poole Hoffmann, V1
Fijal, BA1
Carrasco, JL1
Palomares, N1
Marsá, MD1
Grootens, KP1
Verkes, RJ1
Weiden, P1
Marchesi, C1
Tonna, M1
Maggini, C1
Friedel, RO1
Jackson, WT1
Huston, CS1
May, RS1
Kirby, NL1
Stoves, A1
Khouzam, HR1
Donnelly, NJ1
Szigethy, EM1
Schulz, SC1
Rocca, P1
Marchiaro, L1
Cocuzza, E1
Bogetto, F1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Olanzapine in Patients With Borderline Personality Disorder: A Randomized Double-Blind Comparison With Placebo[NCT00088036]Phase 3450 participants Interventional2004-02-29Completed
Olanzapine Versus Divalproex and Placebo in the Treatment of Mild to Moderate Mania Associated With Bipolar I Disorder[NCT00094549]Phase 4500 participants Interventional2004-10-31Completed
The Study of Olanzapine Plus Fluoxetine in Combination for Treatment-Resistant Depression Without Psychotic Features[NCT00035321]Phase 3600 participants Interventional2002-04-30Completed
Efficacy and Safety of Olanzapine in Patients With Borderline Personality Disorder: A Randomized Flexible Dose Double-Blind Comparison With Placebo[NCT00091650]Phase 3300 participants Interventional2004-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for risperidone and Borderline Personality Disorder

ArticleYear
Emerging evidence for the use of atypical antipsychotics in borderline personality disorder.
    Pharmacopsychiatry, 2005, Volume: 38, Issue:1

    Topics: Antipsychotic Agents; Benzodiazepines; Borderline Personality Disorder; Clinical Trials as Topic; Cl

2005

Trials

3 trials available for risperidone and Borderline Personality Disorder

ArticleYear
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Pharmacogenomic associations with weight gain in olanzapine treatment of patients without schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Borderline Personality Diso

2012
Effectiveness and tolerability of long-acting intramuscular risperidone as adjuvant treatment in refractory borderline personality disorder.
    Psychopharmacology, 2012, Volume: 224, Issue:2

    Topics: Adolescent; Adult; Antipsychotic Agents; Borderline Personality Disorder; Delayed-Action Preparation

2012
Treatment of borderline personality disorder with risperidone.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:3

    Topics: Adult; Aggression; Antipsychotic Agents; Borderline Personality Disorder; Dopamine Antagonists; Fema

2002

Other Studies

5 other studies available for risperidone and Borderline Personality Disorder

ArticleYear
Splitting and pill splitting.
    Psychiatric services (Washington, D.C.), 2007, Volume: 58, Issue:2

    Topics: Adult; Aged; Borderline Personality Disorder; Cost Savings; Defense Mechanisms; Drug Costs; Female;

2007
Obsessive-compulsive disorder followed by psychotic episode in long-term ecstasy misuse.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 2

    Topics: Adolescent; Amphetamine-Related Disorders; Antidepressive Agents, Tricyclic; Antipsychotic Agents; B

2009
Risperidone treatment of borderline personality disorder assessed by a borderline personality disorder-specific outcome measure: a pilot study.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:3

    Topics: Adult; Antipsychotic Agents; Borderline Personality Disorder; Dose-Response Relationship, Drug; Drug

2008
Remission of self-mutilation in a patient with borderline personality during risperidone therapy.
    The Journal of nervous and mental disease, 1997, Volume: 185, Issue:5

    Topics: Adult; Borderline Personality Disorder; Female; Humans; Impulsive Behavior; Risperidone; Self Mutila

1997
Risperidone in comorbid borderline personality disorder and dysthymia.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:4

    Topics: Adult; Alcoholism; Antipsychotic Agents; Borderline Personality Disorder; Comorbidity; Dysthymic Dis

1997