Page last updated: 2024-11-03

risperidone and Bone Loss, Osteoclastic

risperidone has been researched along with Bone Loss, Osteoclastic in 6 studies

Risperidone: A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.
risperidone : A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.

Research Excerpts

ExcerptRelevanceReference
"The aims of this study were to investigate bone mass, body composition and light microscopic pathology examinations of femur in an animal model of schizophrenia (pharmacologically induced by postnatally administered phencyclidine-PCP) and to further examine the effects of chronic treatment with risperidone on these parameters in rats."7.79Chronic risperidone exposure does not show any evidence of bone mass deterioration in animal model of schizophrenia. ( Doknic, M; Jasovic-Gasic, M; Maric, N; Pekic, S; Petronijevic, M; Petronijevic, N; Popovic, V; Radonjic, N; Sopta, J, 2013)
"Risperidone was added to culture medium in clinically relevant doses of 0, 2."5.38Trabecular bone loss after administration of the second-generation antipsychotic risperidone is independent of weight gain. ( Baron, R; Bornstein, S; de Paula, FJ; Dick-de-Paula, I; Houseknecht, KL; Lotinun, S; Maloney, AE; Motyl, KJ; Rosen, CJ, 2012)
" The objective of this study was to determine the prevalence of low BMD in patients with schizophrenia treated with conventional antipsychotics or risperidone and to evaluate any potential relationship with treatment."5.17Bone loss associated with hyperprolactinemia in patients with schizophrenia. ( Jacob, J; Kinon, BJ; Liu-Seifert, H; Stauffer, VL, 2013)
"The aims of this study were to investigate bone mass, body composition and light microscopic pathology examinations of femur in an animal model of schizophrenia (pharmacologically induced by postnatally administered phencyclidine-PCP) and to further examine the effects of chronic treatment with risperidone on these parameters in rats."3.79Chronic risperidone exposure does not show any evidence of bone mass deterioration in animal model of schizophrenia. ( Doknic, M; Jasovic-Gasic, M; Maric, N; Pekic, S; Petronijevic, M; Petronijevic, N; Popovic, V; Radonjic, N; Sopta, J, 2013)
"Risperidone was added to culture medium in clinically relevant doses of 0, 2."1.38Trabecular bone loss after administration of the second-generation antipsychotic risperidone is independent of weight gain. ( Baron, R; Bornstein, S; de Paula, FJ; Dick-de-Paula, I; Houseknecht, KL; Lotinun, S; Maloney, AE; Motyl, KJ; Rosen, CJ, 2012)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Amini, A1
Namvarpour, Z1
Namvarpour, M1
Raoofi, A1
Motyl, KJ2
Beauchemin, M1
Barlow, D1
Le, PT1
Nagano, K1
Treyball, A1
Contractor, A1
Baron, R2
Rosen, CJ2
Houseknecht, KL2
Petronijevic, N1
Sopta, J1
Doknic, M1
Radonjic, N1
Petronijevic, M1
Pekic, S1
Maric, N1
Jasovic-Gasic, M1
Popovic, V1
Lozano, R1
Marin, R1
Santacruz, MJ1
Dick-de-Paula, I1
Maloney, AE1
Lotinun, S1
Bornstein, S1
de Paula, FJ1
Kinon, BJ1
Liu-Seifert, H1
Stauffer, VL1
Jacob, J1

Trials

1 trial available for risperidone and Bone Loss, Osteoclastic

ArticleYear
Bone loss associated with hyperprolactinemia in patients with schizophrenia.
    Clinical schizophrenia & related psychoses, 2013, Volume: 7, Issue:3

    Topics: Adult; Antipsychotic Agents; Bone Density; Bone Resorption; Cross-Sectional Studies; Estradiol; Fema

2013

Other Studies

5 other studies available for risperidone and Bone Loss, Osteoclastic

ArticleYear
Risperidone accelerates bone loss in rats with autistic-like deficits induced by maternal lipopolysaccharides exposure.
    Life sciences, 2020, Oct-01, Volume: 258

    Topics: Animals; Animals, Newborn; Autistic Disorder; Behavior, Animal; Biomechanical Phenomena; Bone Resorp

2020
A novel role for dopamine signaling in the pathogenesis of bone loss from the atypical antipsychotic drug risperidone in female mice.
    Bone, 2017, Volume: 103

    Topics: Animals; Antipsychotic Agents; Bone Resorption; Dopamine; Female; Mice; Mice, Inbred C57BL; Ovariect

2017
Chronic risperidone exposure does not show any evidence of bone mass deterioration in animal model of schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Oct-01, Volume: 46

    Topics: Animals; Animals, Newborn; Antipsychotic Agents; Bone Density; Bone Resorption; Female; Male; Pregna

2013
Pathological bone mineral density in patients on long-term risperidone.
    Clinical schizophrenia & related psychoses, 2014, Volume: 8, Issue:3

    Topics: Antipsychotic Agents; Bone Resorption; Female; Humans; Hyperprolactinemia; Male; Risperidone; Schizo

2014
Trabecular bone loss after administration of the second-generation antipsychotic risperidone is independent of weight gain.
    Bone, 2012, Volume: 50, Issue:2

    Topics: Adiposity; Administration, Oral; Animals; Antipsychotic Agents; Bone Density; Bone Resorption; Cell

2012