Page last updated: 2024-11-04

risedronic acid and Pain

risedronic acid has been researched along with Pain in 17 studies

Risedronic Acid: A pyridine and diphosphonic acid derivative that acts as a CALCIUM CHANNEL BLOCKER and inhibits BONE RESORPTION.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Although etidronate is effective, risedronate offers a shorter duration of therapy, better and longer-lasting remission, significant reductions in pain, and provides additional remission in subjects who exhibited an incomplete response to previous etidronate treatment."5.09A randomized, double-blind comparison of risedronate and etidronate in the treatment of Paget's disease of bone. Paget's Risedronate/Etidronate Study Group. ( Axelrod, DW; Bekker, PJ; Brown, JP; Hoseyni, MS; Miller, PD; Siris, ES, 1999)
"Back and knee pain is a widespread health problem and a serious threat to the quality of life (QOL) in middle-aged and older adults, as it frequently accompanies osteoporosis and osteoarthritis."2.76Comparison of the effects of elcatonin and risedronate on back and knee pain by electroalgometry using fall of skin impedance and quality of life assessment using SF-36. ( Fujii, Y; Fujita, T; Miyauchi, A; Nakajima, M; Ohue, M; Takagi, Y, 2011)
"After the pain is resolved and the examination shows improvement, patients may gradually increase their level of activity."2.47Stress fractures: diagnosis, treatment, and prevention. ( Kapil, N; Patel, DS; Roth, M, 2011)
"Comorbid factors such as ischemic heart disease, hip osteoarthritis, and higher values of FRAX blunted the effects of QOL of the treatment."1.38The effect of risedronate (17.5 mg/week) treatment on quality of life in Japanese women with osteoporosis: a prospective observational study. ( Hayakawa, Y; Iinuma, N; Itoh, M; Iwayama, S; Kamisaki, T; Nakamura, T; Nishikawa, M; Osawa, M; Suzuki, H; Yamaguchi, H, 2012)
"Risedronate decreased bone cancer-related bone destruction and pain-related behavior and decreased the spinal expression of glial fibrillary acidic protein, whereas NE-10790 had no effect on these parameters."1.35Cancer-induced bone loss and associated pain-related behavior is reduced by risedronate but not its phosphonocarboxylate analog NE-10790. ( Croucher, PI; Ding, M; Ebetino, FH; Gallagher, O; Hald, A; Hansen, RR; Heegaard, AM; Kassem, M; Thomsen, MW, 2009)
"Pamidronate treatment (60 mg/day for 3 days) was repeated in patients without evidence of PDB remission at day 120."1.32Risedronate and pamidronate treatment in the clinical management of patients with severe Paget's disease of bone and acquired resistance to bisphosphonates. ( Mossetti, G; Nunziata, V; Rendina, D; Sorrentino, M; Viceconti, R, 2004)
"Up to 80-90% of patients with treatment-requiring osteoporosis are not receiving specific treatment."1.31[Weeks of pain, vertebral body fractures during sleep, invalidism. Save your osteoporosis patients from this fate]. ( Begerow, B; Hinz, C; Minne, HW; Pfeifer, M; Pollähne, W, 2002)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (17.65)18.2507
2000's8 (47.06)29.6817
2010's6 (35.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amin, NL1
James, RM1
Phillips, R1
Imai, T1
Tanaka, S1
Kawakami, K1
Miyazaki, T1
Hagino, H1
Shiraki, M1
Hald, A1
Hansen, RR1
Thomsen, MW1
Ding, M1
Croucher, PI1
Gallagher, O1
Ebetino, FH1
Kassem, M1
Heegaard, AM1
Fujita, T1
Ohue, M1
Nakajima, M1
Fujii, Y1
Miyauchi, A1
Takagi, Y1
Patel, DS1
Roth, M1
Kapil, N1
Meulenbeld, HJ1
van Werkhoven, ED1
Coenen, JL1
Creemers, GJ1
Loosveld, OJ1
de Jong, PC1
Ten Tije, AJ1
Fosså, SD1
Polee, M1
Gerritsen, W1
Dalesio, O1
de Wit, R1
Nakamura, T1
Osawa, M1
Itoh, M1
Yamaguchi, H1
Iinuma, N1
Hayakawa, Y1
Suzuki, H1
Kamisaki, T1
Iwayama, S1
Nishikawa, M1
Minne, HW1
Pollähne, W1
Pfeifer, M1
Begerow, B1
Hinz, C1
Rendina, D1
Mossetti, G1
Viceconti, R1
Sorrentino, M1
Nunziata, V1
Wysowski, DK1
Chang, JT1
Wright, SA1
Millar, AM1
Coward, SM1
Finch, MB1
Carvalho, AP1
Bezerra, MM1
Girão, VC1
Cunha, FQ1
Rocha, FA1
Bingham, CO1
Buckland-Wright, JC1
Garnero, P1
Cohen, SB1
Dougados, M1
Adami, S1
Clauw, DJ1
Spector, TD1
Pelletier, JP1
Raynauld, JP1
Strand, V1
Simon, LS1
Meyer, JM1
Cline, GA1
Beary, JF1
Felson, DT1
Kim, YJ1
Hosking, DJ1
Eusebio, RA1
Chines, AA1
Miller, PD2
Brown, JP1
Siris, ES1
Hoseyni, MS1
Axelrod, DW1
Bekker, PJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Placebo Controlled Trial Testing The Effect of Zoledronic Acid on Hip Osteoarthritis[NCT04303026]Phase 370 participants (Anticipated)Interventional2020-03-02Recruiting
Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention[NCT05204836]Phase 156 participants (Anticipated)Interventional2023-05-16Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for risedronic acid and Pain

ArticleYear
QUESTION 1: Should we be using bisphosphonates for osteonecrosis complicating childhood acute lymphoblastic leukaemia?
    Archives of disease in childhood, 2016, Volume: 101, Issue:3

    Topics: Adolescent; Alendronate; Antineoplastic Agents; Bone Density Conservation Agents; Diphosphonates; Fe

2016
Stress fractures: diagnosis, treatment, and prevention.
    American family physician, 2011, Jan-01, Volume: 83, Issue:1

    Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; Calcium, Diet

2011
The futility of current approaches to chondroprotection.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:5

    Topics: Anti-Bacterial Agents; Bone Density Conservation Agents; Cartilage, Articular; Chondrocytes; Doxycyc

2007
The use of risedronate in Paget's disease.
    Bone, 1999, Volume: 24, Issue:5 Suppl

    Topics: Alkaline Phosphatase; Bone Resorption; Clinical Trials as Topic; Etidronic Acid; Fibrous Dysplasia,

1999

Trials

5 trials available for risedronic acid and Pain

ArticleYear
Health state utility values and patient-reported outcomes before and after vertebral and non-vertebral fractures in an osteoporosis clinical trial.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2017, Volume: 28, Issue:6

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Bone Density Conservation Agents; Drug Therapy,

2017
Comparison of the effects of elcatonin and risedronate on back and knee pain by electroalgometry using fall of skin impedance and quality of life assessment using SF-36.
    Journal of bone and mineral metabolism, 2011, Volume: 29, Issue:5

    Topics: Aged; Back Pain; Bone Density Conservation Agents; Calcitonin; Etidronic Acid; Female; Humans; Knee

2011
Randomised phase II/III study of docetaxel with or without risedronate in patients with metastatic Castration Resistant Prostate Cancer (CRPC), the Netherlands Prostate Study (NePro).
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:16

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Phytogenic; Antineoplastic Com

2012
Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis st
    Arthritis and rheumatism, 2006, Volume: 54, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Bone Density Conservation Agents; Cartilage; Disease Pro

2006
Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis st
    Arthritis and rheumatism, 2006, Volume: 54, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Bone Density Conservation Agents; Cartilage; Disease Pro

2006
Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis st
    Arthritis and rheumatism, 2006, Volume: 54, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Bone Density Conservation Agents; Cartilage; Disease Pro

2006
Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis st
    Arthritis and rheumatism, 2006, Volume: 54, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Bone Density Conservation Agents; Cartilage; Disease Pro

2006
A randomized, double-blind comparison of risedronate and etidronate in the treatment of Paget's disease of bone. Paget's Risedronate/Etidronate Study Group.
    The American journal of medicine, 1999, Volume: 106, Issue:5

    Topics: Administration, Oral; Aged; Alkaline Phosphatase; Bone and Bones; Calcium Channel Blockers; Double-B

1999

Other Studies

8 other studies available for risedronic acid and Pain

ArticleYear
Cancer-induced bone loss and associated pain-related behavior is reduced by risedronate but not its phosphonocarboxylate analog NE-10790.
    International journal of cancer, 2009, Sep-01, Volume: 125, Issue:5

    Topics: Acid Phosphatase; Animals; Behavior, Animal; Bone Density Conservation Agents; Bone Neoplasms; Bone

2009
The effect of risedronate (17.5 mg/week) treatment on quality of life in Japanese women with osteoporosis: a prospective observational study.
    Journal of bone and mineral metabolism, 2012, Volume: 30, Issue:6

    Topics: Aged; Aged, 80 and over; Asian People; Bone Density; Bone Density Conservation Agents; Comorbidity;

2012
[Weeks of pain, vertebral body fractures during sleep, invalidism. Save your osteoporosis patients from this fate].
    MMW Fortschritte der Medizin, 2002, Oct-31, Volume: 144, Issue:44

    Topics: Activities of Daily Living; Age Factors; Alendronate; Analgesics, Opioid; Anti-Inflammatory Agents,

2002
Risedronate and pamidronate treatment in the clinical management of patients with severe Paget's disease of bone and acquired resistance to bisphosphonates.
    Calcified tissue international, 2004, Volume: 75, Issue:3

    Topics: Administration, Oral; Alkaline Phosphatase; Calcitriol; Clodronic Acid; Diphosphonates; Drug Toleran

2004
Alendronate and risedronate: reports of severe bone, joint, and muscle pain.
    Archives of internal medicine, 2005, Feb-14, Volume: 165, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alendronate; Arthralgia; Bone and Bones; Child; Etidroni

2005
Chronic diffuse sclerosing osteomyelitis treated with risedronate.
    The Journal of rheumatology, 2005, Volume: 32, Issue:7

    Topics: Adult; Calcium Channel Blockers; Chronic Disease; Etidronic Acid; Female; Humans; Osteomyelitis; Pai

2005
Anti-inflammatory and anti-nociceptive activity of risedronate in experimental pain models in rats and mice.
    Clinical and experimental pharmacology & physiology, 2006, Volume: 33, Issue:7

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Diphosphonates;

2006
Paget's disease of bone: reduction of disease activity with oral risedronate.
    Bone, 1998, Volume: 22, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alkaline Phosphatase; Calcium; Calcium Channel Blocke

1998