risedronic acid has been researched along with Osteoarthritis in 9 studies
Risedronic Acid: A pyridine and diphosphonic acid derivative that acts as a CALCIUM CHANNEL BLOCKER and inhibits BONE RESORPTION.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteoarthritis was surgically induced on one knee of 32 New Zealand White rabbits using the contralateral as healthy controls." | 5.40 | Effects of glucosamine and risedronate alone or in combination in an experimental rabbit model of osteoarthritis. ( Caeiro, JR; González-Cantalapiedra, A; Guede, D; López-Peña, M; Muñoz, F; Permuy, M, 2014) |
| "Osteoarthritis is thought to be the most prevalent chronic and disabling joint disease in animals and humans and its treatment is a major orthopaedic challenge because there is no ideal drug treatment to preserve joint structure and function, as well as to ameliorate the symptomatology of the disease." | 1.42 | Comparison of various SYSADOA for the osteoarthritis treatment: an experimental study in rabbits. ( Caeiro, JR; González-Cantalapiedra, A; Guede, D; López-Peña, M; Muñoz, F; Permuy, M, 2015) |
| "Osteoarthritis was surgically induced on one knee of 32 New Zealand White rabbits using the contralateral as healthy controls." | 1.40 | Effects of glucosamine and risedronate alone or in combination in an experimental rabbit model of osteoarthritis. ( Caeiro, JR; González-Cantalapiedra, A; Guede, D; López-Peña, M; Muñoz, F; Permuy, M, 2014) |
| " In two groups, anterior cruciate ligament transection was performed and half were left untreated, and the other half dosed with risedronate (0." | 1.35 | Preservation of periarticular cancellous morphology and mechanical stiffness in post-traumatic experimental osteoarthritis by antiresorptive therapy. ( Boyd, SK; Doschak, MR; MacNeil, JA; Zernicke, RF, 2008) |
| " We surgically transected the anterior cruciate ligament (ACLX) in two groups of rabbits; the first group was dosed with BP (risedronate, 0." | 1.32 | Antiresorptive therapy conserves some periarticular bone and ligament mechanical properties after anterior cruciate ligament disruption in the rabbit knee. ( Bray, RC; Doschak, MR; Hanley, DA; Wohl, GR; Zernicke, RF, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thomsen, JS | 1 |
| Straarup, TS | 1 |
| Danielsen, CC | 1 |
| Oxlund, H | 1 |
| Brüel, A | 1 |
| Permuy, M | 2 |
| Guede, D | 2 |
| López-Peña, M | 2 |
| Muñoz, F | 2 |
| González-Cantalapiedra, A | 2 |
| Caeiro, JR | 2 |
| Bruyère, O | 1 |
| Burlet, N | 1 |
| Delmas, PD | 1 |
| Rizzoli, R | 1 |
| Cooper, C | 1 |
| Reginster, JY | 1 |
| Yemisci, OU | 1 |
| Yalbuzdag, SA | 1 |
| Karatas, M | 1 |
| Doschak, MR | 2 |
| Wohl, GR | 1 |
| Hanley, DA | 1 |
| Bray, RC | 1 |
| Zernicke, RF | 2 |
| Felson, DT | 1 |
| Kim, YJ | 1 |
| MacNeil, JA | 1 |
| Boyd, SK | 1 |
| Kawasaki, T | 1 |
| Kurosawa, H | 1 |
| Ikeda, H | 1 |
| Kim, SG | 1 |
| Osawa, A | 1 |
| Takazawa, Y | 1 |
| Kubota, M | 1 |
| Ishijima, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Placebo Controlled Trial Testing The Effect of Zoledronic Acid on Hip Osteoarthritis[NCT04303026] | Phase 3 | 70 participants (Anticipated) | Interventional | 2020-03-02 | Recruiting | ||
| Pilot, Open Non-controled Trial to Assess the Feasibility of Implementing Objective Parameters as Primary Endpoints in a Clinical Trial With Patients Affected by Knee Osteoarthritis[NCT03421054] | 8 participants (Actual) | Interventional | 2018-03-19 | Completed | |||
| Double Blind, Placebo Controlled Trial to Evaluate the Effects of a Nutraceutical Containing High-Molecular-Weight Hyaluronic Acid (HA) and Acetyl-11-Keto-Beta-Boswellic Acid (AKBA) in Patients Affected by Knee Osteoarthritis[NCT03612986] | 72 participants (Actual) | Interventional | 2018-08-22 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for risedronic acid and Osteoarthritis
| Article | Year |
|---|---|
Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system.
Topics: Anthraquinones; Antirheumatic Agents; Calcitonin; Chondroitin Sulfates; Clinical Trials as Topic; Et | 2008 |
Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system.
Topics: Anthraquinones; Antirheumatic Agents; Calcitonin; Chondroitin Sulfates; Clinical Trials as Topic; Et | 2008 |
Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system.
Topics: Anthraquinones; Antirheumatic Agents; Calcitonin; Chondroitin Sulfates; Clinical Trials as Topic; Et | 2008 |
Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system.
Topics: Anthraquinones; Antirheumatic Agents; Calcitonin; Chondroitin Sulfates; Clinical Trials as Topic; Et | 2008 |
The futility of current approaches to chondroprotection.
Topics: Anti-Bacterial Agents; Bone Density Conservation Agents; Cartilage, Articular; Chondrocytes; Doxycyc | 2007 |
1 trial available for risedronic acid and Osteoarthritis
| Article | Year |
|---|---|
Additive effects of glucosamine or risedronate for the treatment of osteoarthritis of the knee combined with home exercise: a prospective randomized 18-month trial.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; | 2008 |
6 other studies available for risedronic acid and Osteoarthritis
| Article | Year |
|---|---|
No effect of risedronate on articular cartilage damage in the Dunkin Hartley guinea pig model of osteoarthritis.
Topics: Animals; Bone Density Conservation Agents; Bone Resorption; Calcification, Physiologic; Cartilage, A | 2013 |
Effects of glucosamine and risedronate alone or in combination in an experimental rabbit model of osteoarthritis.
Topics: Animals; Bone Density Conservation Agents; Etidronic Acid; Female; Glucosamine; Humans; Osteoarthrit | 2014 |
Comparison of various SYSADOA for the osteoarthritis treatment: an experimental study in rabbits.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Arthrography; Bone Density Conservation Agents; C | 2015 |
Risedronate-induced arthritis.
Topics: Bone Density Conservation Agents; Etidronic Acid; Female; Humans; Middle Aged; Osteoarthritis; Osteo | 2010 |
Antiresorptive therapy conserves some periarticular bone and ligament mechanical properties after anterior cruciate ligament disruption in the rabbit knee.
Topics: Animals; Anterior Cruciate Ligament; Biomechanical Phenomena; Bone Density; Etidronic Acid; Osteoart | 2004 |
Preservation of periarticular cancellous morphology and mechanical stiffness in post-traumatic experimental osteoarthritis by antiresorptive therapy.
Topics: Animals; Bone Density Conservation Agents; Bone Resorption; Computer Simulation; Disease Models, Ani | 2008 |