Page last updated: 2024-11-04

risedronic acid and Body Weight

risedronic acid has been researched along with Body Weight in 18 studies

Risedronic Acid: A pyridine and diphosphonic acid derivative that acts as a CALCIUM CHANNEL BLOCKER and inhibits BONE RESORPTION.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Retrospective single-center cohort study of osteoporosis patients treated with alendronate or risedronate for at least 2 years and then discontinued their bisphosphonate for a drug holiday."3.83Determinants of change in bone mineral density and fracture risk during bisphosphonate holiday. ( Adams-Huet, B; Maalouf, NM; Poindexter, JR; Xu, LH, 2016)
" Long-term use of bisphosphonates prevented reductions in BMI and body weight, usually observed in elderly women."1.48Bisphosphonates prevent age-related weight loss in Japanese postmenopausal women. ( Inoue, S; Kuroda, T; Shiraki, M; Tanaka, S; Uenishi, K; Urano, F; Urano, T, 2018)
"The purpose of the present study was to examine the effect of pretreatment with risedronate and/or vitamin K2 and treatment continuation with reduced dosing frequency of the drugs on the early cancellous bone loss induced by ovariectomy (OVX) in rats."1.33Beneficial effect of pretreatment and treatment continuation with risedronate and vitamin K2 on cancellous bone loss after ovariectomy in rats: a bone histomorphometry study. ( Iwamoto, J; Sato, Y; Shen, CL; Takeda, T; Yeh, JK, 2006)
"The relationship between bone turnover and bone tissue and material properties was examined in ovariectomized (OVX) rats treated with risedronate in combination with or without vitamin K2."1.32Regulation of mineral-to-matrix ratio of lumbar trabecular bone in ovariectomized rats treated with risedronate in combination with or without vitamin K2. ( Ikeda, S; Ito, M; Nakamura, T; Otomo, H; Phipps, RJ; Sakai, A; Tanaka, S, 2004)
" The study was designed as a dose-response study, and the site-specific effects of immobilization and of treatment are described."1.31Treatment with risedronate or alendronate prevents hind-limb immobilization-induced loss of bone density and strength in adult female rats. ( Mackey, MS; Mosekilde, L; Phipps, RJ; Thomsen, JS, 2000)
" These findings indicated that the long-term administration of PGE2 alone cannot maintain or continue to add bone mass in ovx rats but that co-treatment of a PGE2 with an anti-resorptive or activation agent can resist the influence of the mechanostat induced bone loss as well as continue to add bone."1.29Co-treatment of PGE2 and risedronate is better than PGE2 alone in the long-term treatment of ovariectomized-induced osteopenic rats. ( Chen, YY; Ijiri, K; Jee, WS; Ke, HZ; Ma, Y, 1995)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (22.22)18.2507
2000's10 (55.56)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Urano, T1
Shiraki, M1
Kuroda, T1
Tanaka, S2
Urano, F1
Uenishi, K1
Inoue, S1
Xu, LH1
Adams-Huet, B1
Poindexter, JR1
Maalouf, NM1
Iwamoto, J4
Matsumoto, H1
Takeda, T4
Sato, Y4
Liu, X1
Yeh, JK4
Matsumoto, Y1
Mikuni-Takagaki, Y1
Kozai, Y1
Miyagawa, K1
Naruse, K1
Wakao, H1
Kawamata, R1
Kashima, I1
Sakurai, T1
Fujita, Y1
Watanabe, K1
Uchikanbori, S1
Maki, K1
Sugiyama, T1
Meakin, LB1
Galea, GL1
Jackson, BF1
Lanyon, LE1
Ebetino, FH1
Russell, RG1
Price, JS1
Erben, RG1
Mosekilde, L2
Thomsen, JS2
Weber, K1
Stahr, K1
Leyshon, A1
Smith, SY1
Phipps, R1
Otomo, H1
Sakai, A1
Ikeda, S1
Ito, M1
Phipps, RJ3
Nakamura, T1
Seki, A2
Yamada, H2
Shen, CL2
Fuchs, RK1
Burr, DB1
Jee, WS3
Lin, BY1
Ma, YF1
Ke, HZ3
Hall, DG1
Stoica, G1
Ma, Y1
Chen, YY1
Ijiri, K1
Mackey, MS1
Libouban, H1
Moreau, MF1
Legrand, E1
Baslé, MF1
Audran, M1
Chappard, D1
Tang, LY1
Kimmel, DB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Neoadjuvant Chemotherapy With or Without Zometa on Occult Micrometastases and Bone Density in Women With Locally Advanced Breast Cancer[NCT00242203]Phase 2120 participants (Actual)Interventional2002-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

18 other studies available for risedronic acid and Body Weight

ArticleYear
Bisphosphonates prevent age-related weight loss in Japanese postmenopausal women.
    Journal of bone and mineral metabolism, 2018, Volume: 36, Issue:6

    Topics: Aged; Alendronate; Asian People; Biomarkers; Body Composition; Body Mass Index; Body Weight; Bone De

2018
Determinants of change in bone mineral density and fracture risk during bisphosphonate holiday.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2016, Volume: 27, Issue:5

    Topics: Aged; Alendronate; Body Weight; Bone Density; Bone Density Conservation Agents; Diphosphonates; Fema

2016
Effects of vitamin K(2) and risedronate on bone formation and resorption, osteocyte lacunar system, and porosity in the cortical bone of glucocorticoid-treated rats.
    Calcified tissue international, 2008, Volume: 83, Issue:2

    Topics: Animals; Body Weight; Bone Density Conservation Agents; Bone Resorption; Disease Models, Animal; Dru

2008
Prior treatment with vitamin K(2) significantly improves the efficacy of risedronate.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2009, Volume: 20, Issue:11

    Topics: Animals; Body Weight; Bone Density Conservation Agents; Drug Administration Schedule; Drug Evaluatio

2009
Effects of risedronate on cortical and trabecular bone of the mandible in glucocorticoid-treated growing rats.
    American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 2011, Volume: 139, Issue:3

    Topics: Anatomy, Cross-Sectional; Animals; Body Weight; Bone Density; Bone Density Conservation Agents; Etid

2011
Risedronate does not reduce mechanical loading-related increases in cortical and trabecular bone mass in mice.
    Bone, 2011, Volume: 49, Issue:1

    Topics: Animals; Body Weight; Bone and Bones; Etidronic Acid; Female; Fluorescent Dyes; Mice; Mice, Inbred C

2011
Prevention of bone loss in ovariectomized rats by combined treatment with risedronate and 1alpha,25-dihydroxyvitamin D3.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2002, Volume: 17, Issue:8

    Topics: Animals; Biomechanical Phenomena; Body Weight; Bone Density; Calcitriol; Etidronic Acid; Female; Ost

2002
Regulation of mineral-to-matrix ratio of lumbar trabecular bone in ovariectomized rats treated with risedronate in combination with or without vitamin K2.
    Journal of bone and mineral metabolism, 2004, Volume: 22, Issue:5

    Topics: Absorptiometry, Photon; Amino Acids; Animals; Biomechanical Phenomena; Body Weight; Bone Density; Bo

2004
Comparative effects of risedronate and calcitriol on cancellous bone in rats with glucocorticoid-induced osteopenia.
    Journal of nutritional science and vitaminology, 2006, Volume: 52, Issue:1

    Topics: Animals; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Density; Bone Diseases, Metaboli

2006
Beneficial effect of pretreatment and treatment continuation with risedronate and vitamin K2 on cancellous bone loss after ovariectomy in rats: a bone histomorphometry study.
    Journal of nutritional science and vitaminology, 2006, Volume: 52, Issue:5

    Topics: Absorptiometry, Photon; Analysis of Variance; Animals; Body Weight; Bone Density; Bone Density Conse

2006
Effect of risedronate on the cortical and cancellous bone mass and mechanical properties in ovariectomized rats: a comparison with the effects of alfacalcidol.
    Journal of nutritional science and vitaminology, 2006, Volume: 52, Issue:6

    Topics: Analysis of Variance; Animals; Body Weight; Bone Density; Bone Density Conservation Agents; Bone Res

2006
Recovery of trabecular and cortical bone turnover after discontinuation of risedronate and alendronate therapy in ovariectomized rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2008, Volume: 23, Issue:10

    Topics: Alendronate; Animals; Body Weight; Bone Density; Bone Density Conservation Agents; Bone Remodeling;

2008
Extra cancellous bone induced by combined prostaglandin E2 and risedronate administration is maintained after their withdrawal in older female rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:6

    Topics: Aging; Analysis of Variance; Animals; Body Weight; Bone Development; Bone Resorption; Calcium Channe

1995
Effect of the bisphosphonate risedronate on bone metastases in a rat mammary adenocarcinoma model system.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1994, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Analysis of Variance; Animals; Body Weight; Bone and Bones; Bone Neoplasms; Bone Res

1994
Co-treatment of PGE2 and risedronate is better than PGE2 alone in the long-term treatment of ovariectomized-induced osteopenic rats.
    Bone, 1995, Volume: 17, Issue:4 Suppl

    Topics: Aging; Animals; Body Weight; Bone Development; Bone Diseases, Metabolic; Dinoprostone; Drug Therapy,

1995
Treatment with risedronate or alendronate prevents hind-limb immobilization-induced loss of bone density and strength in adult female rats.
    Bone, 2000, Volume: 27, Issue:5

    Topics: Alendronate; Animals; Body Weight; Etidronic Acid; Female; Femur; Hindlimb Suspension; Osteoporosis;

2000
Comparison insight dual X-ray absorptiometry (DXA), histomorphometry, ash weight, and morphometric indices for bone evaluation in an animal model (the orchidectomized rat) of male osteoporosis.
    Calcified tissue international, 2001, Volume: 68, Issue:1

    Topics: Absorptiometry, Photon; Animals; Body Weight; Bone and Bones; Bone Density; Climacteric; Disease Mod

2001
Restoring and maintaining bone in osteopenic female rat skeleton: I. Changes in bone mass and structure.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1992, Volume: 7, Issue:9

    Topics: Aging; Animals; Body Weight; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Bone Resorption

1992