rimantadine has been researched along with Orthomyxoviridae Infections in 33 studies
Rimantadine: An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Orthomyxoviridae Infections: Virus diseases caused by the ORTHOMYXOVIRIDAE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rimantadine was administered (30 mg/kg, p." | 2.69 | Pharmacokinetics and therapeutic efficacy of rimantadine in horses experimentally infected with influenza virus A2. ( Chambers, TM; Harkins, JD; Holland, RE; Lehner, AF; Lu, M; Rees, WA; Tobin, T, 1999) |
| "By attaching multiple copies of the influenza M2 ion channel inhibitors amantadine (1) and rimantadine (2) to polymeric chains, we endeavored to recover their potency in inhibiting drug-resistant influenza viruses." | 1.39 | Conjugation to polymeric chains of influenza drugs targeting M2 ion channels partially restores inhibition of drug-resistant mutants. ( Chen, J; Klibanov, AM; Larson, AM, 2013) |
| " At higher dosage (0." | 1.38 | Prophylactic and therapeutic combination effects of rimantadine and oseltamivir against influenza virus A (H3N2) infection in mice. ( Galabov, AS; Gegova, G; Simeonova, L, 2012) |
| " The pharmacokinetic parameters and bioavailability of TZV were calculated after the administration of TZV to rabbits." | 1.36 | Antiviral properties, metabolism, and pharmacokinetics of a novel azolo-1,2,4-triazine-derived inhibitor of influenza A and B virus replication. ( Charushin, V; Chupakhin, O; Deev, S; Deeva, E; Ivanov, A; Karpenko, I; Kiselev, O; Kochetkov, S; Kukhanova, M; Rusinov, V; Smirnova, O; Ulomsky, E; Yanvarev, D, 2010) |
| "Rimantadine hydrochloride was used as the positive control drug." | 1.35 | Antiviral activity of nano carbon fullerene lipidosome against influenza virus in vitro. ( Cheng, L; Geng, C; Gong, M; Ji, H; Jiang, W; Wang, Z; Xiao, H; Yang, Z, 2008) |
| "Rimantadine HCl was assessed for its effect on influenza A virus titer in lungs of infected BALB/c mice." | 1.28 | Efficacy of rimantadine hydrochloride in the treatment of influenza infection of mice. ( Bruns, M; Ennis, FA; Herrmann, JE; West, K, 1989) |
| "5 h after oral administration, and the elimination half-life was 1." | 1.27 | Pharmacokinetics and metabolism of rimantadine hydrochloride in mice and dogs. ( Blasecki, JW; Gaylord, JC; Hoffman, HE; Shalaby, LM; Whitney, CC, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (30.30) | 18.7374 |
| 1990's | 7 (21.21) | 18.2507 |
| 2000's | 9 (27.27) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Karpenko, I | 1 |
| Deev, S | 1 |
| Kiselev, O | 1 |
| Charushin, V | 1 |
| Rusinov, V | 1 |
| Ulomsky, E | 1 |
| Deeva, E | 1 |
| Yanvarev, D | 1 |
| Ivanov, A | 1 |
| Smirnova, O | 1 |
| Kochetkov, S | 1 |
| Chupakhin, O | 1 |
| Kukhanova, M | 1 |
| Khomenko, TM | 1 |
| Zarubaev, VV | 1 |
| Kireeva, MV | 1 |
| Volobueva, AS | 1 |
| Slita, AV | 1 |
| Borisevich, SS | 1 |
| Korchagina, DV | 1 |
| Komarova, NI | 1 |
| Volcho, KP | 1 |
| Salakhutdinov, NF | 1 |
| Larson, AM | 1 |
| Chen, J | 1 |
| Klibanov, AM | 1 |
| Ji, H | 1 |
| Yang, Z | 1 |
| Jiang, W | 1 |
| Geng, C | 1 |
| Gong, M | 1 |
| Xiao, H | 1 |
| Wang, Z | 1 |
| Cheng, L | 1 |
| Zoidis, G | 1 |
| Tsotinis, A | 1 |
| Kolocouris, N | 1 |
| Kelly, JM | 1 |
| Prathalingam, SR | 1 |
| Naesens, L | 1 |
| De Clercq, E | 2 |
| Loginova, SIa | 1 |
| Borisevich, SV | 1 |
| Maksimov, VA | 1 |
| Bondarev, VP | 1 |
| Nebol'sin, VE | 2 |
| Du, QS | 1 |
| Huang, RB | 1 |
| Wang, SQ | 1 |
| Chou, KC | 1 |
| Bantia, S | 1 |
| Kellogg, D | 1 |
| Parker, CD | 1 |
| Babu, YS | 1 |
| Shishkina, LN | 1 |
| Skarnovich, MO | 1 |
| Kabanov, AS | 1 |
| Sergeev, AA | 1 |
| Erdyneeva, UB | 1 |
| Serova, OA | 1 |
| Demina, OK | 1 |
| Agafonov, AP | 1 |
| Stavskiĭ, EA | 1 |
| Drozdov, IG | 1 |
| Simeonova, L | 2 |
| Gegova, G | 5 |
| Galabov, AS | 2 |
| Serkedjieva, J | 2 |
| Roeva, I | 1 |
| Angelova, M | 1 |
| Dolashka, P | 1 |
| Voelter, WG | 1 |
| Härtl, A | 1 |
| Sauerbrei, A | 1 |
| Stelzner, A | 1 |
| Wutzler, P | 1 |
| Tonew, E | 1 |
| Indulen, MK | 1 |
| Dzeguze, DR | 1 |
| Shneĭder, MA | 1 |
| Shtil'bans, EB | 1 |
| Rachkovskaia, LA | 1 |
| Vetlugina, LA | 1 |
| Nikitina, ET | 1 |
| Denys, A | 1 |
| Korczak, E | 1 |
| Kulig, A | 1 |
| Błoch, P | 1 |
| Sygut, J | 1 |
| Aleksandrov, BA | 1 |
| Pozharisskiĭ, KM | 1 |
| Likhachev, AIa | 1 |
| Anisimov, WN | 1 |
| Okulov, VB | 1 |
| Manolova, N | 3 |
| Serkedzhieva, Iu | 2 |
| Maksimova, V | 2 |
| Uzunov, S | 1 |
| Dzeguze, D | 1 |
| Indulen, M | 1 |
| Ivanova, E | 1 |
| Rees, WA | 1 |
| Harkins, JD | 1 |
| Lu, M | 1 |
| Holland, RE | 1 |
| Lehner, AF | 1 |
| Tobin, T | 1 |
| Chambers, TM | 1 |
| Kandel, R | 1 |
| Hartshorn, KL | 1 |
| Tantcheva, L | 1 |
| Pavlova, E | 1 |
| Savov, V | 1 |
| Galabov, A | 1 |
| Mileva, M | 1 |
| Braykova, A | 1 |
| Kamyshentsev, MV | 1 |
| Volchek, IV | 1 |
| Platonov, VG | 1 |
| Isakov, VA | 1 |
| Zolotukhin, NN | 1 |
| Pancheva, S | 1 |
| Sweet, C | 1 |
| Hayden, FG | 2 |
| Jakeman, KJ | 1 |
| Grambas, S | 1 |
| Hay, AJ | 1 |
| Herrmann, JE | 2 |
| West, K | 2 |
| Bruns, M | 2 |
| Ennis, FA | 2 |
| Zhirnov, OP | 1 |
| Hoffman, HE | 1 |
| Gaylord, JC | 1 |
| Blasecki, JW | 1 |
| Shalaby, LM | 1 |
| Whitney, CC | 1 |
| Maksimova-Todorova, V | 1 |
| Webster, RG | 1 |
| Kawaoka, Y | 1 |
| Bean, WJ | 1 |
1 review available for rimantadine and Orthomyxoviridae Infections
| Article | Year |
|---|---|
Prophylaxis and treatment of influenza virus infection.
Topics: Amantadine; Antiviral Agents; Humans; Influenza Vaccines; Neuraminidase; Orthomyxoviridae Infections | 2001 |
1 trial available for rimantadine and Orthomyxoviridae Infections
| Article | Year |
|---|---|
Pharmacokinetics and therapeutic efficacy of rimantadine in horses experimentally infected with influenza virus A2.
Topics: Administration, Oral; Animals; Antibodies, Viral; Antiviral Agents; Area Under Curve; Biological Ava | 1999 |
31 other studies available for rimantadine and Orthomyxoviridae Infections
| Article | Year |
|---|---|
Antiviral properties, metabolism, and pharmacokinetics of a novel azolo-1,2,4-triazine-derived inhibitor of influenza A and B virus replication.
Topics: Animals; Antiviral Agents; Azoles; Disease Models, Animal; Dogs; Drug Design; Hepatocytes; Humans; I | 2010 |
New type of anti-influenza agents based on benzo[d][1,3]dithiol core.
Topics: Animals; Antiviral Agents; Dogs; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A V | 2020 |
Conjugation to polymeric chains of influenza drugs targeting M2 ion channels partially restores inhibition of drug-resistant mutants.
Topics: Amantadine; Animals; Antiviral Agents; Cell Line; Dogs; Drug Carriers; Drug Resistance, Viral; Human | 2013 |
Antiviral activity of nano carbon fullerene lipidosome against influenza virus in vitro.
Topics: Animals; Antiviral Agents; Carbon; Cell Line; Dogs; Dose-Response Relationship, Drug; Drug Delivery | 2008 |
Design and synthesis of bioactive 1,2-annulated adamantane derivatives.
Topics: Amantadine; Animals; Antiviral Agents; Drug Design; Influenza A Virus, H3N2 Subtype; Orthomyxovirida | 2008 |
[Therapeutic efficacy of Ingavirin, a new domestic formulation against influenza A virus (H3N2)].
Topics: Amides; Animals; Antiviral Agents; Caproates; Dicarboxylic Acids; Imidazoles; Indoles; Influenza A V | 2008 |
Designing inhibitors of M2 proton channel against H1N1 swine influenza virus.
Topics: Adamantane; Amino Acid Sequence; Animals; Antiviral Agents; Binding Sites; Drug Design; Drug Resista | 2010 |
Combination of peramivir and rimantadine demonstrate synergistic antiviral effects in sub-lethal influenza A (H3N2) virus mouse model.
Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Cyclopentanes; Disease Models, Animal; Dose-Response | 2010 |
[In vivo efficacy of Ingavirin against pandemic A (H1N1/09)v influenza virus].
Topics: Amides; Animals; Antiviral Agents; Caproates; Dicarboxylic Acids; Female; Imidazoles; Influenza A Vi | 2010 |
Prophylactic and therapeutic combination effects of rimantadine and oseltamivir against influenza virus A (H3N2) infection in mice.
Topics: Animals; Antiviral Agents; Chemoprevention; Disease Models, Animal; Drug Therapy, Combination; Influ | 2012 |
Combined protective effect of a fungal Cu/Zn-containing superoxide dismutase and rimantadine hydrochloride in experimental murine influenza a virus infection.
Topics: Animals; Antiviral Agents; Aprotinin; Copper; Drug Synergism; Drug Therapy, Combination; Lung; Mice; | 2003 |
Influenza infection of the embryonated hen's egg/an alternative model for in vivo evaluation of antiviral compounds.
Topics: Amantadine; Animals; Antiviral Agents; Chick Embryo; Drug Evaluation, Preclinical; Guanidines; Influ | 2004 |
Influenza virus inhibitors available for the chemotherapy and/or chemoprophylaxis of influenza virus infections.
Topics: Amantadine; Animals; Antibiotic Prophylaxis; Antiviral Agents; Humans; Neuraminidase; Orthomyxovirid | 2006 |
Rimantadine and oseltamivir demonstrate synergistic combination effect in an experimental infection with type A (H3N2) influenza virus in mice.
Topics: Administration, Oral; Animals; Antiviral Agents; Cell Line; Cells, Cultured; Disease Models, Animal; | 2006 |
Antiviral action of dipyridamole and its derivatives against influenza virus A.
Topics: Animals; Antiviral Agents; Dipyridamole; Influenza A virus; Mice; Orthomyxoviridae Infections; Riman | 1982 |
[Virus-inhibiting properties of the carbonyl-conjugated pentaene roseofungin].
Topics: Animals; Antiviral Agents; Influenza A virus; Mice; Orthomyxoviridae Infections; Polyenes; Rimantadi | 1984 |
[Antiviral activity of remantadine evaluated by a pathomorphological study of the lungs of mice infected by influenza virus].
Topics: Adamantane; Animals; Influenza A virus; Lung; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections | 1984 |
[Results of tests for carcinogenic, teratogenic and embryotoxic action of remantadin].
Topics: Abnormalities, Drug-Induced; Adamantane; Animals; Embryo, Mammalian; Female; Male; Mice; Neoplasms, | 1982 |
Combined effect of selected antiviral substances of natural and synthetic origin. II. Anti-influenza activity of a combination of a polyphenolic complex isolated from Geranium sanguineum L. and rimantadine in vivo.
Topics: Animals; Antiviral Agents; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; | 1993 |
Combined protective effect of an immunostimulatory bacterial preparation and rimantadine in experimental influenza A virus infection.
Topics: Adjuvants, Immunologic; Animals; Escherichia coli; Female; Influenza A virus; Male; Mice; Orthomyxov | 1997 |
Free radical lipid peroxidation and monooxygenase activity in experimental influenza virus infection after treatment with rimantadine.
Topics: Animals; Antiviral Agents; Disease Models, Animal; Free Radicals; Influenza A virus; Lipid Peroxidat | 2001 |
[Concept of the mechanism of the therapeutic effect of flu chemotherapy].
Topics: Animals; Influenza A virus; Lipid Peroxidation; Mice; Mice, Inbred CBA; Orthomyxoviridae Infections; | 1992 |
[The anti-influenza effect of rimantadine and isoprinosine when used in combination in mice].
Topics: Adjuvants, Immunologic; Animals; Birds; Chick Embryo; Dose-Response Relationship, Drug; Drug Evaluat | 1990 |
Virulence of rimantadine-resistant human influenza A (H3N2) viruses in ferrets.
Topics: Animals; Disease Models, Animal; Drug Resistance, Microbial; Ferrets; Influenza A virus; Influenza A | 1991 |
Effect of rimantadine on cytotoxic T lymphocyte responses and immunity to reinfection in mice infected with influenza A virus.
Topics: Adamantane; Animals; Antibodies, Viral; Influenza A virus; Male; Mice; Mice, Inbred BALB C; Orthomyx | 1990 |
High protection of animals lethally infected with influenza virus by aprotinin-rimantadine combination.
Topics: Adamantane; Animals; Aprotinin; Drug Combinations; Drug Synergism; Influenza A virus; Lung; Mice; Or | 1987 |
Efficacy of rimantadine hydrochloride in the treatment of influenza infection of mice.
Topics: Adamantane; Administration, Oral; Animals; Disease Models, Animal; Influenza A virus; Injections, In | 1989 |
Pharmacokinetics and metabolism of rimantadine hydrochloride in mice and dogs.
Topics: Adamantane; Administration, Oral; Amantadine; Animals; Biological Availability; Dogs; Dose-Response | 1988 |
[Combined action of antiviral substances of natural and synthetic origin. I. The anti-influenza action of a combination of the polyphenol complex isolated from Geranium sanguineum L. and remantadine in vitro and in ovo].
Topics: Adamantane; Animals; Antiviral Agents; Chick Embryo; Culture Techniques; Drug Evaluation, Preclinica | 1986 |
Vaccination as a strategy to reduce the emergence of amantadine- and rimantadine-resistant strains of A/Chick/Pennsylvania/83 (H5N2) influenza virus.
Topics: Adamantane; Amantadine; Animals; Drug Resistance, Microbial; Influenza A virus; Influenza A Virus, H | 1986 |
Combinations of antiviral agents for treatment of influenza virus infections.
Topics: Amantadine; Animals; Antiviral Agents; Drug Synergism; Drug Therapy, Combination; In Vitro Technique | 1986 |