riluzole has been researched along with Retrolental Fibroplasia in 2 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study examined the effects of riluzole, a Food and Drug Administration-approved drug for amyotrophic lateral sclerosis, on VEGF-stimulated endothelial cell proliferation in culture, and on neovascularization in a rat model of retinopathy of prematurity (ROP)." | 7.73 | Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo. ( Hyun, HJ; Koh, JY; Yoo, MH; Yoon, YH, 2005) |
| "The present study examined the effects of riluzole, a Food and Drug Administration-approved drug for amyotrophic lateral sclerosis, on VEGF-stimulated endothelial cell proliferation in culture, and on neovascularization in a rat model of retinopathy of prematurity (ROP)." | 3.73 | Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo. ( Hyun, HJ; Koh, JY; Yoo, MH; Yoon, YH, 2005) |
| "Riluzole is a Food and Drug Administration-approved anti-ALS drug with a favorable adverse effect profile." | 1.34 | Insulin increases retinal hemorrhage in mild oxygen-induced retinopathy in the rat: inhibition by riluzole. ( Cho, KS; Chung, H; Koh, JY; Yoo, MH; Yoon, YH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoo, MH | 2 |
| Hyun, HJ | 1 |
| Koh, JY | 2 |
| Yoon, YH | 2 |
| Chung, H | 1 |
| Cho, KS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Vascular Endothelial Growth Factor Levels in Aqueous, Vitreous and Subretinal Fluid in Patients With Retinopathy of Prematurity Stage V.[NCT00500396] | Phase 4 | 15 participants (Anticipated) | Interventional | 2007-03-31 | Completed | ||
| Vascular Endothelial Growth Factor Levels in Aqueous, Vitreous and Subretinal Fluid in Patients With Retinopathy of Prematurity Stage IV and V[NCT00563121] | Phase 4 | 16 participants (Actual) | Interventional | 2007-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for riluzole and Retrolental Fibroplasia
| Article | Year |
|---|---|
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
Topics: Adolescent; Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Proliferation; Disease | 2005 |
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
Topics: Adolescent; Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Proliferation; Disease | 2005 |
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
Topics: Adolescent; Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Proliferation; Disease | 2005 |
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
Topics: Adolescent; Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Proliferation; Disease | 2005 |
Insulin increases retinal hemorrhage in mild oxygen-induced retinopathy in the rat: inhibition by riluzole.
Topics: Animals; Animals, Newborn; Blotting, Western; Dextrans; Disease Models, Animal; Enzyme-Linked Immuno | 2007 |